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Volumn 169, Issue 3, 2006, Pages 916-926

Macrophage-specific expression of human lysosomal acid lipase corrects inflammation and pathogenic phenotypes in lal-/- mice

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL ESTER; DOXYCYCLINE; LYSOSOMAL ACID LIPASE; LYSOSOME ENZYME; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 33748782801     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.2353/ajpath.2006.051327     Document Type: Article
Times cited : (64)

References (22)
  • 1
    • 0038336760 scopus 로고    scopus 로고
    • Overexpression of dominant negative retinoic acid receptor alpha causes alveolar abnormality in transgenic neonatal lungs
    • Yang L, Naltner A, Yan C: Overexpression of dominant negative retinoic acid receptor alpha causes alveolar abnormality in transgenic neonatal lungs. Endocrinology 2003, 144:3004-3011
    • (2003) Endocrinology , vol.144 , pp. 3004-3011
    • Yang, L.1    Naltner, A.2    Yan, C.3
  • 3
    • 0037307026 scopus 로고    scopus 로고
    • A macrophage colony-stimulating factor receptor-green fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse
    • Sasmono RT, Oceandy D, Pollard JW, Tong W, Pavli P, Wainwright BJ, Ostrowski MC, Himes SR, Hume DA: A macrophage colony-stimulating factor receptor-green fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse. Blood 2003, 101:1155-1163
    • (2003) Blood , vol.101 , pp. 1155-1163
    • Sasmono, R.T.1    Oceandy, D.2    Pollard, J.W.3    Tong, W.4    Pavli, P.5    Wainwright, B.J.6    Ostrowski, M.C.7    Himes, S.R.8    Hume, D.A.9
  • 4
    • 0031657974 scopus 로고    scopus 로고
    • Targeted disruption of the mouse lysosomal acid lipase gene: Long-term survival with massive cholesteryl ester and triglyceride storage
    • Du H, Duanmu M, Witte D, Grabowski GA: Targeted disruption of the mouse lysosomal acid lipase gene: long-term survival with massive cholesteryl ester and triglyceride storage. Hum Mol Genet 1998, 7:1347-1354
    • (1998) Hum Mol Genet , vol.7 , pp. 1347-1354
    • Du, H.1    Duanmu, M.2    Witte, D.3    Grabowski, G.A.4
  • 5
    • 1642379630 scopus 로고    scopus 로고
    • Lysosomal acid lipase deficiency causes respiratory inflammation and destruction in the lung
    • Lian X, Yan C, Yang L, Xu Y, Du H: Lysosomal acid lipase deficiency causes respiratory inflammation and destruction in the lung. Am J Physiol Lung Cell Mol Physiol 2004, 286:L801-L807
    • (2004) Am J Physiol Lung Cell Mol Physiol , vol.286
    • Lian, X.1    Yan, C.2    Yang, L.3    Xu, Y.4    Du, H.5
  • 6
    • 0035064152 scopus 로고    scopus 로고
    • Lysosomal acid lipase-deficient mice: Depletion of white and brown fat, severe hepatosplenomegaly, and shortened life span
    • Du H, Heur M, Duanmu M, Grabowski GA, Hui DY, Witte DP, Mishra J: Lysosomal acid lipase-deficient mice: depletion of white and brown fat, severe hepatosplenomegaly, and shortened life span. J Lipid Res 2001, 42:489-500
    • (2001) J Lipid Res , vol.42 , pp. 489-500
    • Du, H.1    Heur, M.2    Duanmu, M.3    Grabowski, G.A.4    Hui, D.Y.5    Witte, D.P.6    Mishra, J.7
  • 7
    • 24044508876 scopus 로고    scopus 로고
    • Neutral lipids and peroxisome proliferator-activated receptor-{gamma} control pulmonary gene expression and inflammation-triggered pathogenesis in lysosomal acid lipase knockout mice
    • Lian X, Yan C, Qin Y, Knox L, Li T, Du H: Neutral lipids and peroxisome proliferator-activated receptor-{gamma} control pulmonary gene expression and inflammation-triggered pathogenesis in lysosomal acid lipase knockout mice. Am J Pathol 2005, 167:813-821
    • (2005) Am J Pathol , vol.167 , pp. 813-821
    • Lian, X.1    Yan, C.2    Qin, Y.3    Knox, L.4    Li, T.5    Du, H.6
  • 9
    • 84855414679 scopus 로고    scopus 로고
    • Key stages in the acute inflammatory response and their relevance as therapeutic targets
    • Winyard PG: Key stages in the acute inflammatory response and their relevance as therapeutic targets. Methods Mol Biol 2003, 225:3-6
    • (2003) Methods Mol Biol , vol.225 , pp. 3-6
    • Winyard, P.G.1
  • 10
    • 0028972025 scopus 로고
    • 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma
    • Forman BM, Tontonoz P, Chen J, Brun RP, Spiegelman BM, Evans RM: 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma. Cell 1995, 83:803-812
    • (1995) Cell , vol.83 , pp. 803-812
    • Forman, B.M.1    Tontonoz, P.2    Chen, J.3    Brun, R.P.4    Spiegelman, B.M.5    Evans, R.M.6
  • 11
    • 0032540325 scopus 로고    scopus 로고
    • Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma
    • Nagy L, Tontonoz P, Alvarez JG, Chen H, Evans RM: Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma. Cell 1998, 93:229-240
    • (1998) Cell , vol.93 , pp. 229-240
    • Nagy, L.1    Tontonoz, P.2    Alvarez, J.G.3    Chen, H.4    Evans, R.M.5
  • 12
    • 0034923501 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma and metabolic disease
    • Willson TM, Lambert MH, Kliewer SA: Peroxisome proliferator-activated receptor gamma and metabolic disease. Annu Rev Biochem 2001, 70:341-367
    • (2001) Annu Rev Biochem , vol.70 , pp. 341-367
    • Willson, T.M.1    Lambert, M.H.2    Kliewer, S.A.3
  • 13
    • 19644399543 scopus 로고    scopus 로고
    • Who tidies up the lung?: Listen to cox-2 and nrf2
    • Uhlig S: Who tidies up the lung?: listen to cox-2 and nrf2. Am J Respir Crit Care Med 2005, 171:1198-1199
    • (2005) Am J Respir Crit Care Med , vol.171 , pp. 1198-1199
    • Uhlig, S.1
  • 14
    • 30044449982 scopus 로고    scopus 로고
    • Resolution of inflammation: The beginning programs the end
    • Serhan CN, Savill J: Resolution of inflammation: the beginning programs the end. Nat Immunol 2005, 6:1191-1197
    • (2005) Nat Immunol , vol.6 , pp. 1191-1197
    • Serhan, C.N.1    Savill, J.2
  • 15
    • 0033960059 scopus 로고    scopus 로고
    • Molecular cloning, genomic organization and cell-binding characteristics of mouse Spalpha
    • Gebe JA, Llewellyn M, Hoggatt H, Aruffo A: Molecular cloning, genomic organization and cell-binding characteristics of mouse Spalpha. Immunology 2000, 99:78-86
    • (2000) Immunology , vol.99 , pp. 78-86
    • Gebe, J.A.1    Llewellyn, M.2    Hoggatt, H.3    Aruffo, A.4
  • 16
    • 0033579824 scopus 로고    scopus 로고
    • Increased susceptibility of thymocytes to apoptosis in mice lacking AIM, a novel murine macrophage-derived soluble factor belonging to the scavenger receptor cysteine-rich domain superfamily
    • Miyazaki T, Hirokami Y, Matsuhashi N, Takatsuka H, Naito M: Increased susceptibility of thymocytes to apoptosis in mice lacking AIM, a novel murine macrophage-derived soluble factor belonging to the scavenger receptor cysteine-rich domain superfamily. J Exp Med 1999, 189:413-422
    • (1999) J Exp Med , vol.189 , pp. 413-422
    • Miyazaki, T.1    Hirokami, Y.2    Matsuhashi, N.3    Takatsuka, H.4    Naito, M.5
  • 17
    • 0030698250 scopus 로고    scopus 로고
    • The Maf transcription factors: Regulators of differentiation
    • Blank V, Andrews NC: The Maf transcription factors: regulators of differentiation. Trends Biochem Sci 1997, 22:437-441
    • (1997) Trends Biochem Sci , vol.22 , pp. 437-441
    • Blank, V.1    Andrews, N.C.2
  • 18
    • 0028072795 scopus 로고
    • MafB, a new Maf family transcription activator that can associate with Maf and Fos but not with Jun
    • Kataoka K, Fujiwara KT, Noda M, Nishizawa M: MafB, a new Maf family transcription activator that can associate with Maf and Fos but not with Jun. Mol Cell Biol 1994, 14:7581-7591
    • (1994) Mol Cell Biol , vol.14 , pp. 7581-7591
    • Kataoka, K.1    Fujiwara, K.T.2    Noda, M.3    Nishizawa, M.4
  • 19
    • 0039550799 scopus 로고    scopus 로고
    • Spi-C, a novel Ets protein that is temporally regulated during B lymphocyte development
    • Bemark M, Martensson A, Liberg D, Leanderson T: Spi-C, a novel Ets protein that is temporally regulated during B lymphocyte development. J Biol Chem 1999, 274:10259-10267
    • (1999) J Biol Chem , vol.274 , pp. 10259-10267
    • Bemark, M.1    Martensson, A.2    Liberg, D.3    Leanderson, T.4
  • 21
    • 0033146096 scopus 로고    scopus 로고
    • Matrix metalloproteinases, matrix degradation and more
    • Shapiro SD, Senior RM: Matrix metalloproteinases, matrix degradation and more. Am J Respir Cell Mol Biol 1999, 20:1100-1102
    • (1999) Am J Respir Cell Mol Biol , vol.20 , pp. 1100-1102
    • Shapiro, S.D.1    Senior, R.M.2
  • 22
    • 0037693895 scopus 로고    scopus 로고
    • Matrix metalloproteinases and tissue inhibitors of metalloproteinases: Structure, function, and biochemistry
    • Visse R, Naguse H: Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry. Circ Res 92:827-839
    • Circ Res , vol.92 , pp. 827-839
    • Visse, R.1    Naguse, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.