-
2
-
-
0033568130
-
Clinical significance of alterations of chromosome 8 in highgrade, advanced, nonmetastatic prostate carcinoma
-
Sato K, Qian J, Slezak JM, Lieber MM, Bostwick DG, Bergstralh EJ, et al. Clinical significance of alterations of chromosome 8 in highgrade, advanced, nonmetastatic prostate carcinoma. J Natl Cancer Inst 1999;91:1574-80.
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 1574-1580
-
-
Sato, K.1
Qian, J.2
Slezak, J.M.3
Lieber, M.M.4
Bostwick, D.G.5
Bergstralh, E.J.6
-
3
-
-
0141569009
-
Myc-driven murine prostate cancer shares molecular features with human prostate tumors
-
Ellwood-Yen K, Graeber TG, Wongvipat J, Iruela-Arispe ML, Zhang J, Matusik R, et al. Myc-driven murine prostate cancer shares molecular features with human prostate tumors. Cancer Cell 2003;4:223-38.
-
(2003)
Cancer Cell
, vol.4
, pp. 223-238
-
-
Ellwood-Yen, K.1
Graeber, T.G.2
Wongvipat, J.3
Iruela-Arispe, M.L.4
Zhang, J.5
Matusik, R.6
-
4
-
-
37549008310
-
Widespread microRNA repression by Myc contributes to tumorigenesis
-
Chang TC, Yu D, Lee YS, Wentzel EA, Arking DE, West KM, et al. Widespread microRNA repression by Myc contributes to tumorigenesis. Nat Genet 2008;40:43-50.
-
(2008)
Nat Genet
, vol.40
, pp. 43-50
-
-
Chang, T.C.1
Yu, D.2
Lee, Y.S.3
Wentzel, E.A.4
Arking, D.E.5
West, K.M.6
-
5
-
-
33748522684
-
Balance of Yin and Yang: Ubiquitylationmediated regulation of p53 and c-Myc
-
Dai MS, Jin Y, Gallegos JR, Lu H. Balance of Yin and Yang: ubiquitylationmediated regulation of p53 and c-Myc. Neoplasia 2006;8:630-44.
-
(2006)
Neoplasia
, vol.8
, pp. 630-644
-
-
Dai, M.S.1
Jin, Y.2
Gallegos, J.R.3
Lu, H.4
-
6
-
-
20444467290
-
A microRNA polycistron as a potential human oncogene
-
He L, Thomson JM, Hemann MT, Hernando-Monge E, Mu D, Goodson S, et al. A microRNA polycistron as a potential human oncogene. Nature 2005;435:828-33.
-
(2005)
Nature
, vol.435
, pp. 828-833
-
-
He, L.1
Thomson, J.M.2
Hemann, M.T.3
Hernando-Monge, E.4
Mu, D.5
Goodson, S.6
-
7
-
-
34347401998
-
The ubiquitin-specific protease USP28 is required for MYC stability
-
Popov N, Wanzel M, Madiredjo M, Zhang D, Beijersbergen R, Bernards R, et al. The ubiquitin-specific protease USP28 is required for MYC stability. Nat Cell Biol 2007;9:765-74.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 765-774
-
-
Popov, N.1
Wanzel, M.2
Madiredjo, M.3
Zhang, D.4
Beijersbergen, R.5
Bernards, R.6
-
8
-
-
51349157982
-
The MYCN oncogene is a direct target of miR-34a
-
Wei JS, Song YK, Durinck S, Chen QR, Cheuk AT, Tsang P, et al. The MYCN oncogene is a direct target of miR-34a. Oncogene 2008;27:5204-13.
-
(2008)
Oncogene
, vol.27
, pp. 5204-5213
-
-
Wei, J.S.1
Song, Y.K.2
Durinck, S.3
Chen, Q.R.4
Cheuk, A.T.5
Tsang, P.6
-
9
-
-
51049123624
-
Genomic profiling of microRNA and messenger RNA reveals deregulated microRNA expression in prostate cancer
-
Ambs S, Prueitt RL, Yi M, Hudson RS, Howe TM, Petrocca F, et al. Genomic profiling of microRNA and messenger RNA reveals deregulated microRNA expression in prostate cancer. Cancer Res 2008;68:6162-70.
-
(2008)
Cancer Res
, vol.68
, pp. 6162-6170
-
-
Ambs, S.1
Prueitt, R.L.2
Yi, M.3
Hudson, R.S.4
Howe, T.M.5
Petrocca, F.6
-
10
-
-
33144490646
-
A microRNA expression signature of human solid tumors defines cancer gene targets
-
Volinia S, Calin GA, Liu CG, Ambs S, Cimmino A, Petrocca F, et al. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci U S A 2006;103:2257-61.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 2257-2261
-
-
Volinia, S.1
Calin, G.A.2
Liu, C.G.3
Ambs, S.4
Cimmino, A.5
Petrocca, F.6
-
11
-
-
34247593034
-
Impaired microRNA processing enhances cellular transformation and tumorigenesis
-
Kumar MS, Lu J, Mercer KL, Golub TR, Jacks T. Impaired microRNA processing enhances cellular transformation and tumorigenesis. Nat Genet 2007;39:673-7.
-
(2007)
Nat Genet
, vol.39
, pp. 673-677
-
-
Kumar, M.S.1
Lu, J.2
Mercer, K.L.3
Golub, T.R.4
Jacks, T.5
-
12
-
-
36549026364
-
Prediction and preliminary validation of oncogene regulation by miRNAs
-
Koscianska E, Baev V, Skreka K, Oikonomaki K, Rusinov V, Tabler M, et al. Prediction and preliminary validation of oncogene regulation by miRNAs. BMC Mol Biol 2007;8:79.
-
(2007)
BMC Mol Biol
, vol.8
, pp. 79
-
-
Koscianska, E.1
Baev, V.2
Skreka, K.3
Oikonomaki, K.4
Rusinov, V.5
Tabler, M.6
-
13
-
-
57149097456
-
MYC translocation-negative classical Burkitt lymphoma cases: An alternative pathogenetic mechanism involving miRNA deregulation
-
Leucci E, Cocco M, Onnis A, De Falco G, van Cleef P, Bellan C, et al. MYC translocation-negative classical Burkitt lymphoma cases: an alternative pathogenetic mechanism involving miRNA deregulation. J Pathol 2008;216:440-50.
-
(2008)
J Pathol
, vol.216
, pp. 440-450
-
-
Leucci, E.1
Cocco, M.2
Onnis, A.3
De Falco, G.4
van Cleef, P.5
Bellan, C.6
-
14
-
-
62549148270
-
p53 represses c-Myc through induction of the tumor suppressor miR-145
-
Sachdeva M, Zhu S, Wu F, Wu H, Walia V, Kumar S, et al. p53 represses c-Myc through induction of the tumor suppressor miR-145. Proc Natl Acad Sci U S A 2009;106:3207-12.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 3207-3212
-
-
Sachdeva, M.1
Zhu, S.2
Wu, F.3
Wu, H.4
Walia, V.5
Kumar, S.6
-
15
-
-
35449003175
-
MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells
-
Sampson VB, Rong NH, Han J, Yang Q, Aris V, Soteropoulos P, et al. MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells. Cancer Res 2007;67:9762-70.
-
(2007)
Cancer Res
, vol.67
, pp. 9762-9770
-
-
Sampson, V.B.1
Rong, N.H.2
Han, J.3
Yang, Q.4
Aris, V.5
Soteropoulos, P.6
-
16
-
-
20444479428
-
c-Myc-regulated microRNAs modulate E2F1 expression
-
O'Donnell KA, Wentzel EA, Zeller KI, Dang CV, Mendell JT. c-Myc-regulated microRNAs modulate E2F1 expression. Nature 2005;435:839-43.
-
(2005)
Nature
, vol.435
, pp. 839-843
-
-
O'Donnell, K.A.1
Wentzel, E.A.2
Zeller, K.I.3
Dang, C.V.4
Mendell, J.T.5
-
17
-
-
28344456279
-
A genomic and functional inventory of deubiquitinating enzymes
-
Nijman SM, Luna-Vargas MP, Velds A, Brummelkamp TR, Dirac AM, Sixma TK, et al. A genomic and functional inventory of deubiquitinating enzymes. Cell 2005;123:773-86.
-
(2005)
Cell
, vol.123
, pp. 773-786
-
-
Nijman, S.M.1
Luna-Vargas, M.P.2
Velds, A.3
Brummelkamp, T.R.4
Dirac, A.M.5
Sixma, T.K.6
-
18
-
-
3242774545
-
HAUSP is required for p53 destabilization
-
Cummins JM, Vogelstein B. HAUSP is required for p53 destabilization. Cell Cycle 2004;3:689-92.
-
(2004)
Cell Cycle
, vol.3
, pp. 689-692
-
-
Cummins, J.M.1
Vogelstein, B.2
-
19
-
-
0037061508
-
Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization
-
Li M, Chen D, Shiloh A, Luo J, Nikolaev AY, Qin J, et al. Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization. Nature 2002;416:648-53.
-
(2002)
Nature
, vol.416
, pp. 648-653
-
-
Li, M.1
Chen, D.2
Shiloh, A.3
Luo, J.4
Nikolaev, A.Y.5
Qin, J.6
-
20
-
-
19444367393
-
Loss of HAUSP-mediated deubiquitination contributes to DNA damage-induced destabilization of Hdmx and Hdm2
-
Meulmeester E, Maurice MM, Boutell C, Teunisse AF, Ovaa H, Abraham TE, et al. Loss of HAUSP-mediated deubiquitination contributes to DNA damage-induced destabilization of Hdmx and Hdm2. Mol Cell 2005;18:565-76.
-
(2005)
Mol Cell
, vol.18
, pp. 565-576
-
-
Meulmeester, E.1
Maurice, M.M.2
Boutell, C.3
Teunisse, A.F.4
Ovaa, H.5
Abraham, T.E.6
-
21
-
-
70449105984
-
Suppression of cancer cell growth by promoting cyclin D1 degradation
-
Shan J, Zhao W, Gu W. Suppression of cancer cell growth by promoting cyclin D1 degradation. Mol Cell 2009;36:469-76.
-
(2009)
Mol Cell
, vol.36
, pp. 469-476
-
-
Shan, J.1
Zhao, W.2
Gu, W.3
-
22
-
-
33847212425
-
The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2
-
Stevenson LF, Sparks A, Allende-Vega N, Xirodimas DP, Lane DP, Saville MK. The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2. Embo J 2007;26:976-86.
-
(2007)
Embo J
, vol.26
, pp. 976-986
-
-
Stevenson, L.F.1
Sparks, A.2
Allende-Vega, N.3
Xirodimas, D.P.4
Lane, D.P.5
Saville, M.K.6
-
23
-
-
12144286902
-
The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer
-
Graner E, Tang D, Rossi S, Baron A, Migita T, Weinstein LJ, et al. The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer. Cancer Cell 2004;5:253-61.
-
(2004)
Cancer Cell
, vol.5
, pp. 253-261
-
-
Graner, E.1
Tang, D.2
Rossi, S.3
Baron, A.4
Migita, T.5
Weinstein, L.J.6
-
24
-
-
33746820622
-
The isopeptidase USP2a protects human prostate cancer from apoptosis
-
Priolo C, Tang D, Brahamandan M, Benassi B, Sicinska E, Ogino S, et al. The isopeptidase USP2a protects human prostate cancer from apoptosis. Cancer Res 2006;66:8625-32.
-
(2006)
Cancer Res
, vol.66
, pp. 8625-8632
-
-
Priolo, C.1
Tang, D.2
Brahamandan, M.3
Benassi, B.4
Sicinska, E.5
Ogino, S.6
-
25
-
-
38049100559
-
An androgen-regulated miRNA suppresses Bak1 expression and induces androgenindependent growth of prostate cancer cells
-
Shi XB, Xue L, Yang J, Ma AH, Zhao J, Xu M, et al. An androgen-regulated miRNA suppresses Bak1 expression and induces androgenindependent growth of prostate cancer cells. Proc Natl Acad Sci U S A 2007;104:19983-8.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 19983-19988
-
-
Shi, X.B.1
Xue, L.2
Yang, J.3
Ma, A.H.4
Zhao, J.5
Xu, M.6
-
26
-
-
60149087720
-
MicroRNA profile analysis of human prostate cancers
-
Tong AW, Fulgham P, Jay C, Chen P, Khalil I, Liu S, et al. MicroRNA profile analysis of human prostate cancers. Cancer Gene Ther 2009;16:206-16.
-
(2009)
Cancer Gene Ther
, vol.16
, pp. 206-216
-
-
Tong, A.W.1
Fulgham, P.2
Jay, C.3
Chen, P.4
Khalil, I.5
Liu, S.6
-
27
-
-
10844295905
-
-
Berger R, Febbo PG, Majumder PK, Zhao JJ, Mukherjee S, Signoretti S, et al. Androgen-induced differentiation and tumorigenicity of human prostate epithelial cells. 2004;64:8867.
-
(2004)
Androgen-induced differentiation and tumorigenicity of human prostate epithelial cells
, vol.64
, pp. 8867
-
-
Berger, R.1
Febbo, P.G.2
Majumder, P.K.3
Zhao, J.J.4
Mukherjee, S.5
Signoretti, S.6
-
28
-
-
34250163202
-
Peroxisome proliferator-activated receptor alpha regulates a microRNA-mediated signaling cascade responsible for hepatocellular proliferation
-
Shah YM, Morimura K, Yang Q, Tanabe T, Takagi M, Gonzalez FJ. Peroxisome proliferator-activated receptor alpha regulates a microRNA-mediated signaling cascade responsible for hepatocellular proliferation. Mol Cell Biol 2007;27:4238-47.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 4238-4247
-
-
Shah, Y.M.1
Morimura, K.2
Yang, Q.3
Tanabe, T.4
Takagi, M.5
Gonzalez, F.J.6
-
29
-
-
77954255681
-
Integrative genomic profiling of human prostate cancer
-
Taylor BS, Schultz N, Hieronymus H, Gopalan A, Xiao Y, Carver BS, et al. Integrative genomic profiling of human prostate cancer. Cancer Cell 2010;18:11-22.
-
(2010)
Cancer Cell
, vol.18
, pp. 11-22
-
-
Taylor, B.S.1
Schultz, N.2
Hieronymus, H.3
Gopalan, A.4
Xiao, Y.5
Carver, B.S.6
-
30
-
-
34548803950
-
MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth
-
Corney DC, Flesken-Nikiti A, Godwin AK, Wang W, Nikitin AY. MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth. Cancer Res 2007;67:8433-8.
-
(2007)
Cancer Res
, vol.67
, pp. 8433-8438
-
-
Corney, D.C.1
Flesken-Nikiti, A.2
Godwin, A.K.3
Wang, W.4
Nikitin, A.Y.5
-
31
-
-
35748961986
-
p53 enters the microRNA world
-
Hermeking H. p53 enters the microRNA world. Cancer Cell 2007;12:414-8.
-
(2007)
Cancer Cell
, vol.12
, pp. 414-418
-
-
Hermeking, H.1
-
32
-
-
84872996399
-
-
Available at
-
Available at: www.http://astor.som.jhmi.edu/~marchion/labML/benassi. html
-
-
-
-
33
-
-
31144459985
-
Oncogenic pathway signatures in human cancers as a guide to targeted therapies
-
Bild AH, Yao G, Chang JT, Wang Q, Potti A, Chasse D, et al. Oncogenic pathway signatures in human cancers as a guide to targeted therapies. Nature 2006;439:353-7.
-
(2006)
Nature
, vol.439
, pp. 353-357
-
-
Bild, A.H.1
Yao, G.2
Chang, J.T.3
Wang, Q.4
Potti, A.5
Chasse, D.6
-
35
-
-
0037183697
-
Transcriptional regulation during p21WAF1/CIP1-induced apoptosis in human ovarian cancer cells
-
Wu Q, Kirschmeier P, Hockenberry T, Yang TY, Brassard DL, Wang L, et al. Transcriptional regulation during p21WAF1/CIP1-induced apoptosis in human ovarian cancer cells. J Biol Chem 2002;277:36329-37.
-
(2002)
J Biol Chem
, vol.277
, pp. 36329-36337
-
-
Wu, Q.1
Kirschmeier, P.2
Hockenberry, T.3
Yang, T.Y.4
Brassard, D.L.5
Wang, L.6
-
36
-
-
33845884027
-
Integrative molecular concept modeling of prostate cancer progression
-
Tomlins SA, Mehra R, Rhodes DR, Cao X, Wang L, Dhanasekaran SM, et al. Integrative molecular concept modeling of prostate cancer progression. Nat Genet 2007;39:41-51.
-
(2007)
Nat Genet
, vol.39
, pp. 41-51
-
-
Tomlins, S.A.1
Mehra, R.2
Rhodes, D.R.3
Cao, X.4
Wang, L.5
Dhanasekaran, S.M.6
-
37
-
-
0026665523
-
Transcriptional activation by the human c-Myc oncoprotein in yeast requires interaction with Max
-
Amati B, Dalton S, Brooks MW, Littlewood TD, Evan GI, Land H. Transcriptional activation by the human c-Myc oncoprotein in yeast requires interaction with Max. Nature 1992;359:423-6.
-
(1992)
Nature
, vol.359
, pp. 423-426
-
-
Amati, B.1
Dalton, S.2
Brooks, M.W.3
Littlewood, T.D.4
Evan, G.I.5
Land, H.6
-
38
-
-
50249133616
-
Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesis
-
Gurel B, Iwata T, Koh CM, Jenkins RB, Lan F, Van Dang C, et al. Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesis. Mod Pathol 2008;21:1156-67.
-
(2008)
Mod Pathol
, vol.21
, pp. 1156-1167
-
-
Gurel, B.1
Iwata, T.2
Koh, C.M.3
Jenkins, R.B.4
Lan, F.5
Van Dang, C.6
-
39
-
-
23144464363
-
Transcriptional regulation and transformation by Myc proteins
-
Adhikary S, Eilers M. Transcriptional regulation and transformation by Myc proteins. Nat Rev Mol Cell Biol 2005;6:635-45.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 635-645
-
-
Adhikary, S.1
Eilers, M.2
-
40
-
-
0027408096
-
Mad: A heterodimeric partner for Max that antagonizes Myc transcriptional activity
-
Ayer DE, Kretzner L, Eisenman RN. Mad: a heterodimeric partner for Max that antagonizes Myc transcriptional activity. Cell 1993;72:211-22.
-
(1993)
Cell
, vol.72
, pp. 211-222
-
-
Ayer, D.E.1
Kretzner, L.2
Eisenman, R.N.3
-
41
-
-
33646236796
-
Decrease in c-Myc activity enhances cancer cell sensitivity to vinblastine
-
Bressin C, Bourgarel-Rey V, Carre M, Pourroy B, Arango D, Braguer D, et al. Decrease in c-Myc activity enhances cancer cell sensitivity to vinblastine. Anticancer Drugs 2006;17:181-7.
-
(2006)
Anticancer Drugs
, vol.17
, pp. 181-187
-
-
Bressin, C.1
Bourgarel-Rey, V.2
Carre, M.3
Pourroy, B.4
Arango, D.5
Braguer, D.6
-
42
-
-
0030998763
-
Role of oncogenes in resistance and killing by cancer therapeutic agents
-
el-Deiry WS. Role of oncogenes in resistance and killing by cancer therapeutic agents. Curr Opin Oncol 1997;9:79-87.
-
(1997)
Curr Opin Oncol
, vol.9
, pp. 79-87
-
-
el-Deiry, W.S.1
-
43
-
-
62149098010
-
Mechanisms of gene amplification and evidence of coamplification in drug-resistant human osteosarcoma cell lines
-
Hattinger CM, Stoico G, Michelacci F, Pasello M, Scionti I, Remondini D, et al. Mechanisms of gene amplification and evidence of coamplification in drug-resistant human osteosarcoma cell lines. Genes Chromosomes Cancer 2009;48:289-309.
-
(2009)
Genes Chromosomes Cancer
, vol.48
, pp. 289-309
-
-
Hattinger, C.M.1
Stoico, G.2
Michelacci, F.3
Pasello, M.4
Scionti, I.5
Remondini, D.6
-
45
-
-
2642551603
-
Development of the proteasome inhibitor Velcade (Bortezomib)
-
Adams J, Kauffman M. Development of the proteasome inhibitor Velcade (Bortezomib). Cancer Invest 2004;22:304-11.
-
(2004)
Cancer Invest
, vol.22
, pp. 304-311
-
-
Adams, J.1
Kauffman, M.2
-
46
-
-
12444269118
-
Discovery of inhibitors that elucidate the role of UCH-L1 activity in the H1299 lung cancer cell line
-
Liu Y, Lashuel HA, Choi S, Xing X, Case A, Ni J, et al. Discovery of inhibitors that elucidate the role of UCH-L1 activity in the H1299 lung cancer cell line. Chem Biol 2003;10:837-46.
-
(2003)
Chem Biol
, vol.10
, pp. 837-846
-
-
Liu, Y.1
Lashuel, H.A.2
Choi, S.3
Xing, X.4
Case, A.5
Ni, J.6
-
47
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C[T]) method
-
Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C[T]) method. Methods 2001;25:402-8.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
48
-
-
19044391072
-
Gene expression correlates of clinical prostate cancer behavior
-
Singh D, Febbo PG, Ross K, Jackson DG, Manola J, Ladd C, et al. Gene expression correlates of clinical prostate cancer behavior. Cancer Cell 2002;1:203-9.
-
(2002)
Cancer Cell
, vol.1
, pp. 203-209
-
-
Singh, D.1
Febbo, P.G.2
Ross, K.3
Jackson, D.G.4
Manola, J.5
Ladd, C.6
|