메뉴 건너뛰기




Volumn 19, Issue 3, 2013, Pages 247-262

Locally advanced lung cancer: An optimal setting for vaccines and other immunotherapies

Author keywords

Abscopal effect; Chemotherapy; Cytotoxic T lymphocyte associated antigen 4 (CTLA 4); Immunotherapy; Locally advanced; Lung cancer; Programmed death 1 (PD 1); Radiation therapy; Stage 3; Vaccines

Indexed keywords

AGATOLIMOD; BELAGENPUMATUCEL L; BMS 936559; CANCER VACCINE; CARBOPLATIN; CD28 ANTIGEN; CIMAVAX; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; EMEPEPIMUT S; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IPILIMUMAB; MAGEA 3; MDX 1105; MELANOMA ANTIGEN 3; MK 3475; NIVOLUMAB; PACLITAXEL; TALACTOFERRIN; TG 4010; TICILIMUMAB; TUMOR ANTIGEN; UNCLASSIFIED DRUG;

EID: 84880099830     PISSN: 15289117     EISSN: 1540336X     Source Type: Journal    
DOI: 10.1097/PPO.0b013e318292e51a     Document Type: Review
Times cited : (16)

References (112)
  • 1
    • 84867054956 scopus 로고    scopus 로고
    • Nonmelanoma skin cancer in solid organ transplant recipients: Update on epidemiology, risk factors, and management
    • Tessari G, Girolomoni G. Nonmelanoma skin cancer in solid organ transplant recipients: update on epidemiology, risk factors, and management. Dermatol Surg. 2012;38:1622-1630.
    • (2012) Dermatol Surg , vol.38 , pp. 1622-1630
    • Tessari, G.1    Girolomoni, G.2
  • 2
    • 84871714329 scopus 로고    scopus 로고
    • Incidence of primary and second cancers in renal transplant recipients: A multicenter cohort study
    • Tessari G, Naldi L, Boschiero L, et al. Incidence of primary and second cancers in renal transplant recipients: a multicenter cohort study. Am J Transplant. 2013;13:214-221.
    • (2013) Am J Transplant , vol.13 , pp. 214-221
    • Tessari, G.1    Naldi, L.2    Boschiero, L.3
  • 3
    • 0030792989 scopus 로고    scopus 로고
    • Anti-Hu antibodies in patients with small-cell lung cancer: Association with complete response to therapy and improved survival
    • Graus F, Dalmou J, Rene R, et al. Anti-Hu antibodies in patients with small-cell lung cancer: association with complete response to therapy and improved survival. J Clin Oncol. 1997;15:2866-2872.
    • (1997) J Clin Oncol , vol.15 , pp. 2866-2872
    • Graus, F.1    Dalmou, J.2    Rene, R.3
  • 4
    • 84875535374 scopus 로고    scopus 로고
    • Trial watch: Prognostic and predictive value of the immune infiltrate in cancer
    • Senovilla L, Vacchelli E, Galon J, et al. Trial watch: prognostic and predictive value of the immune infiltrate in cancer. Oncoimmunology. 2012;1:1323-1343.
    • (2012) Oncoimmunology , vol.1 , pp. 1323-1343
    • Senovilla, L.1    Vacchelli, E.2    Galon, J.3
  • 5
    • 33646371011 scopus 로고    scopus 로고
    • Foxp3 expressing CD4+ CD25+ and CD8+CD28- T regulatory cells in the peripheral blood of patients with lung cancer and pleural mesothelioma
    • Meloni F, Morosini M, Solari N, et al. Foxp3 expressing CD4+ CD25+ and CD8+CD28- T regulatory cells in the peripheral blood of patients with lung cancer and pleural mesothelioma. Hum Immunol. 2006;67:1-12.
    • (2006) Hum Immunol , vol.67 , pp. 1-12
    • Meloni, F.1    Morosini, M.2    Solari, N.3
  • 6
    • 24944580634 scopus 로고    scopus 로고
    • Regulatory T cells and cytokines in malignant pleural effusions secondary to mesothelioma and carcinoma
    • DeLong P, Carroll RG, Henry AC, et al. Regulatory T cells and cytokines in malignant pleural effusions secondary to mesothelioma and carcinoma. Cancer Biol Ther. 2005;4:342-346.
    • (2005) Cancer Biol Ther , vol.4 , pp. 342-346
    • Delong, P.1    Carroll, R.G.2    Henry, A.C.3
  • 7
    • 41149162625 scopus 로고    scopus 로고
    • Effects of chemoradiation on tumor-host interactions: The immunologic side
    • author reply 3
    • Formenti SC, Demaria S. Effects of chemoradiation on tumor-host interactions: the immunologic side. J Clin Oncol. 2008;26:1562-1563; author reply 3.
    • (2008) J Clin Oncol , vol.26 , pp. 1562-1563
    • Formenti, S.C.1    Demaria, S.2
  • 8
    • 0037598759 scopus 로고    scopus 로고
    • Radiation-induced leukocyte adhesion to endothelium in normal pancreas and in pancreatic carcinoma of the rat
    • Ryschich E, Harms W, Loeffler T, et al. Radiation-induced leukocyte adhesion to endothelium in normal pancreas and in pancreatic carcinoma of the rat. Int J Cancer. 2003;105:506-511.
    • (2003) Int J Cancer , vol.105 , pp. 506-511
    • Ryschich, E.1    Harms, W.2    Loeffler, T.3
  • 9
    • 78049265321 scopus 로고    scopus 로고
    • A pilot study on the immunogenicity of dendritic cell vaccination during adjuvant oxaliplatin/capecitabine chemotherapy in colon cancer patients
    • Lesterhuis WJ, de Vries IJ, Aarntzen EA, et al. A pilot study on the immunogenicity of dendritic cell vaccination during adjuvant oxaliplatin/capecitabine chemotherapy in colon cancer patients. Br J Cancer. 2010;103:1415-1421.
    • (2010) Br J Cancer , vol.103 , pp. 1415-1421
    • Lesterhuis, W.J.1    De Vries, I.J.2    Aarntzen, E.A.3
  • 10
    • 77953701142 scopus 로고    scopus 로고
    • Immunogenic tumor cell death for optimal anticancer therapy: The calreticulin exposure pathway
    • Zitvogel L, Kepp O, Senovilla L, et al. Immunogenic tumor cell death for optimal anticancer therapy: the calreticulin exposure pathway. Clin Cancer Res. 2010;16:3100-3104.
    • (2010) Clin Cancer Res , vol.16 , pp. 3100-3104
    • Zitvogel, L.1    Kepp, O.2    Senovilla, L.3
  • 11
    • 84880088056 scopus 로고    scopus 로고
    • Loss of antigen crosspresentation after complete tumor resection is associated with the generation of protective tumor-specific CD8(+) T-cell immunity
    • Brown MD, van der Most R, Vivian JB, et al. Loss of antigen crosspresentation after complete tumor resection is associated with the generation of protective tumor-specific CD8(+) T-cell immunity. Oncoimmunology. 2012;1:1084-1094.
    • (2012) Oncoimmunology , vol.1 , pp. 1084-1094
    • Brown, M.D.1    Van Der Most, R.2    Vivian, J.B.3
  • 14
    • 84863690997 scopus 로고    scopus 로고
    • The effects of TLR activation on T-cell development and differentiation
    • Jin B, Sun T, Yu XH, et al. The effects of TLR activation on T-cell development and differentiation. Clin Dev Immunol. 2012;2012: 836485.
    • (2012) Clin Dev Immunol , vol.2012 , pp. 836485
    • Jin, B.1    Sun, T.2    Yu, X.H.3
  • 15
    • 84875169169 scopus 로고    scopus 로고
    • Alarmins, inflammasomes and immunity
    • Said-Sadier N, Ojcius DM. Alarmins, inflammasomes and immunity. Biomed J. 2012;35:437-449.
    • (2012) Biomed J , vol.35 , pp. 437-449
    • Said-Sadier, N.1    Ojcius, D.M.2
  • 16
    • 84934440020 scopus 로고    scopus 로고
    • Progress and trends in complement therapeutics
    • Ricklin D, Lambris JD. Progress and trends in complement therapeutics. Adv Exp Med Biol. 2013;735:1-22.
    • (2013) Adv Exp Med Biol , vol.735 , pp. 1-22
    • Ricklin, D.1    Lambris, J.D.2
  • 17
    • 84874205582 scopus 로고    scopus 로고
    • Toward a molecular understanding of adaptive immunity: A chronology, part i
    • Smith KA. Toward a molecular understanding of adaptive immunity: a chronology, part I. Frontiers in immunology. 2012;3:369.
    • (2012) Frontiers in Immunology , vol.3 , pp. 369
    • Smith, K.A.1
  • 19
    • 84874318264 scopus 로고    scopus 로고
    • Protecting and rescuing the effectors: Roles of differentiation and survival in the control of memory T cell development
    • Kurtulus S, Tripathi P, Hildeman DA. Protecting and rescuing the effectors: roles of differentiation and survival in the control of memory T cell development. Front Immunol. 2012;3:404.
    • (2012) Front Immunol , vol.3 , pp. 404
    • Kurtulus, S.1    Tripathi, P.2    Hildeman, D.A.3
  • 20
    • 84880109398 scopus 로고    scopus 로고
    • Targeting the MHC class II antigen presentation pathway in cancer immunotherapy
    • Thibodeau J, Bourgeois-Daigneault MC, Lapointe R. Targeting the MHC class II antigen presentation pathway in cancer immunotherapy. Oncoimmunology. 2012;1:908-916.
    • (2012) Oncoimmunology , vol.1 , pp. 908-916
    • Thibodeau, J.1    Bourgeois-Daigneault, M.C.2    Lapointe, R.3
  • 21
    • 84862122547 scopus 로고    scopus 로고
    • The role of classical and non-classical HLA class I antigens in human tumors
    • Bukur J, Jasinski S, Seliger B. The role of classical and non-classical HLA class I antigens in human tumors. Semin Cancer Biol. 2012;22: 350-358.
    • (2012) Semin Cancer Biol , vol.22 , pp. 350-358
    • Bukur, J.1    Jasinski, S.2    Seliger, B.3
  • 22
    • 84873129546 scopus 로고    scopus 로고
    • CTLA-4 blockade in tumor models: An overview of preclinical and translational research
    • Grosso JF, Jure-Kunkel MN. CTLA-4 blockade in tumor models: an overview of preclinical and translational research. Cancer Immun. 2013;13:5.
    • (2013) Cancer Immun , vol.13 , pp. 5
    • Grosso, J.F.1    Jure-Kunkel, M.N.2
  • 23
    • 84858766182 scopus 로고    scopus 로고
    • The blockade of immune checkpoints in cancer immunotherapy
    • Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer. 2012;12:252-264.
    • (2012) Nat Rev Cancer , vol.12 , pp. 252-264
    • Pardoll, D.M.1
  • 24
    • 79952775415 scopus 로고    scopus 로고
    • Clinical development of mAbs to block the PD1 pathway as an immunotherapy for cancer
    • Kline J, Gajewski TF. Clinical development of mAbs to block the PD1 pathway as an immunotherapy for cancer. Curr Opin Investig Drugs. 2010;11:1354-1359.
    • (2010) Curr Opin Investig Drugs , vol.11 , pp. 1354-1359
    • Kline, J.1    Gajewski, T.F.2
  • 25
    • 78449237499 scopus 로고    scopus 로고
    • Clinical experiences with anti-CD137 and anti-PD1 therapeutic antibodies
    • Ascierto PA, Simeone E, Sznol M, et al. Clinical experiences with anti-CD137 and anti-PD1 therapeutic antibodies. Semin Oncol. 2010;37: 508-516.
    • (2010) Semin Oncol , vol.37 , pp. 508-516
    • Ascierto, P.A.1    Simeone, E.2    Sznol, M.3
  • 26
    • 84861713665 scopus 로고    scopus 로고
    • Adjuvant immunotherapy for non-small cell lung cancer
    • Tucker ZC, Laguna BA, Moon E, et al. Adjuvant immunotherapy for non-small cell lung cancer. Cancer Treat Rev. 2012;38:650-661.
    • (2012) Cancer Treat Rev , vol.38 , pp. 650-661
    • Tucker, Z.C.1    Laguna, B.A.2    Moon, E.3
  • 27
    • 84880101488 scopus 로고    scopus 로고
    • Effects of ionizing radiation on the immune system with special emphasis on the interaction of dendritic and T cells
    • Manda K, Glasow A, Paape D, et al. Effects of ionizing radiation on the immune system with special emphasis on the interaction of dendritic and T cells. Front Oncol. 2012;2:102.
    • (2012) Front Oncol , vol.2 , pp. 102
    • Manda, K.1    Glasow, A.2    Paape, D.3
  • 28
    • 84880090380 scopus 로고    scopus 로고
    • Radiation-induced effects and the immune system in cancer
    • Kaur P, Asea A. Radiation-induced effects and the immune system in cancer. Front Oncol. 2012;2:191.
    • (2012) Front Oncol , vol.2 , pp. 191
    • Kaur, P.1    Asea, A.2
  • 29
    • 84865782617 scopus 로고    scopus 로고
    • Optimizing cancer treatments to induce an acute immune response: Radiation abscopal effects, PAMPs, and DAMPs
    • Ludgate CM. Optimizing cancer treatments to induce an acute immune response: radiation abscopal effects, PAMPs, and DAMPs. Clin Cancer Res. 2012;18:4522-4525.
    • (2012) Clin Cancer Res , vol.18 , pp. 4522-4525
    • Ludgate, C.M.1
  • 30
    • 33646704729 scopus 로고    scopus 로고
    • Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy
    • Reits EA, Hodge JW, Herberts CA, et al. Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy. J Exp Med. 2006;203:1259-1271.
    • (2006) J Exp Med , vol.203 , pp. 1259-1271
    • Reits, E.A.1    Hodge, J.W.2    Herberts, C.A.3
  • 31
    • 84870996402 scopus 로고    scopus 로고
    • Combined immunotherapy with Listeria monocytogenes-based PSAvaccine and radiation therapy leads to a therapeutic response in a murine model of prostate cancer
    • Hannan R, Zhang H, Wallecha A, et al. Combined immunotherapy with Listeria monocytogenes-based PSAvaccine and radiation therapy leads to a therapeutic response in a murine model of prostate cancer. Cancer Immunol Immunother. 2012;61:2227-2238.
    • (2012) Cancer Immunol Immunother , vol.61 , pp. 2227-2238
    • Hannan, R.1    Zhang, H.2    Wallecha, A.3
  • 32
    • 33748085015 scopus 로고    scopus 로고
    • The combination of ionizing radiation and peripheral vaccination produces long-term survival of mice bearing established invasive GL261 gliomas
    • Newcomb EW, Demaria S, Lukyanov Y, et al. The combination of ionizing radiation and peripheral vaccination produces long-term survival of mice bearing established invasive GL261 gliomas. Clin Cancer Res. 2006;12:4730-4737.
    • (2006) Clin Cancer Res , vol.12 , pp. 4730-4737
    • Newcomb, E.W.1    Demaria, S.2    Lukyanov, Y.3
  • 33
    • 84871230007 scopus 로고    scopus 로고
    • Synergy of topical Toll-like receptor 7 agonist with radiation and low-dose cyclophosphamide in a mouse model of cutaneous breast cancer
    • Dewan MZ, Vanpouille-Box C, Kawashima N, et al. Synergy of topical Toll-like receptor 7 agonist with radiation and low-dose cyclophosphamide in a mouse model of cutaneous breast cancer. Clin Cancer Res. 2012;18:6668-6678.
    • (2012) Clin Cancer Res , vol.18 , pp. 6668-6678
    • Dewan, M.Z.1    Vanpouille-Box, C.2    Kawashima, N.3
  • 34
    • 84861630513 scopus 로고    scopus 로고
    • An in situ autologous tumor vaccination with combined radiation therapy and TLR9 agonist therapy
    • Zhang H, Liu L, Yu D, et al. An in situ autologous tumor vaccination with combined radiation therapy and TLR9 agonist therapy. PLoS One. 2012;7:e38111.
    • (2012) PLoS One , vol.7
    • Zhang, H.1    Liu, L.2    Yu, D.3
  • 35
    • 84870880129 scopus 로고    scopus 로고
    • Cytokines in radiobiological responses: A review
    • Schaue D, Kachikwu EL, McBride WH. Cytokines in radiobiological responses: a review. Radiat Res. 2012;178:505-523.
    • (2012) Radiat Res , vol.178 , pp. 505-523
    • Schaue, D.1    Kachikwu, E.L.2    McBride, W.H.3
  • 36
    • 84871538731 scopus 로고    scopus 로고
    • Clinical opportunities in combining immunotherapy with radiation therapy
    • Finkelstein SE, Fishman M. Clinical opportunities in combining immunotherapy with radiation therapy. Front Oncol. 2012;2:169.
    • (2012) Front Oncol , vol.2 , pp. 169
    • Finkelstein, S.E.1    Fishman, M.2
  • 37
    • 84255173555 scopus 로고    scopus 로고
    • Combination of external beam radiotherapy (EBRT) with intratumoral injection of dendritic cells as neo-adjuvant treatment of high-risk soft tissue sarcoma patients
    • Finkelstein SE, Iclozan C, Bui MM, et al. Combination of external beam radiotherapy (EBRT) with intratumoral injection of dendritic cells as neo-adjuvant treatment of high-risk soft tissue sarcoma patients. Int J Radiat Oncol Biol Phys. 2012;82:924-932.
    • (2012) Int J Radiat Oncol Biol Phys , vol.82 , pp. 924-932
    • Finkelstein, S.E.1    Iclozan, C.2    Bui, M.M.3
  • 38
    • 14744275172 scopus 로고    scopus 로고
    • Combination of conformal radiotherapy and intratumoral injection of adoptive dendritic cell immunotherapy in refractory hepatoma
    • Chi KH, Liu SJ, Li CP, et al. Combination of conformal radiotherapy and intratumoral injection of adoptive dendritic cell immunotherapy in refractory hepatoma. J Immunother. 2005;28:129-135.
    • (2005) J Immunother , vol.28 , pp. 129-135
    • Chi, K.H.1    Liu, S.J.2    Li, C.P.3
  • 39
    • 84860503128 scopus 로고    scopus 로고
    • Induction of abscopal antitumor immunity and immunogenic tumor cell death by ionizing irradiation - Implications for cancer therapies
    • Frey B, Rubner Y, Wunderlich R, et al. Induction of abscopal antitumor immunity and immunogenic tumor cell death by ionizing irradiation - implications for cancer therapies. Curr Med Chem. 2012;19:1751-1764.
    • (2012) Curr Med Chem , vol.19 , pp. 1751-1764
    • Frey, B.1    Rubner, Y.2    Wunderlich, R.3
  • 40
    • 84862124594 scopus 로고    scopus 로고
    • Phase 1 study of stereotactic body radiotherapy and interleukin-2-tumor and immunological responses
    • Seung SK, Curti BD, Crittenden M, et al. Phase 1 study of stereotactic body radiotherapy and interleukin-2-tumor and immunological responses. Sci Transl Med. 2012;4:137ra74.
    • (2012) Sci Transl Med , vol.4
    • Seung, S.K.1    Curti, B.D.2    Crittenden, M.3
  • 41
    • 84857815877 scopus 로고    scopus 로고
    • Immunologic correlates of the abscopal effect in a patient with melanoma
    • Postow MA, Callahan MK, Barker CA, et al. Immunologic correlates of the abscopal effect in a patient with melanoma. N Engl J Med. 2012;366:925-931.
    • (2012) N Engl J Med , vol.366 , pp. 925-931
    • Postow, M.A.1    Callahan, M.K.2    Barker, C.A.3
  • 42
    • 0037376788 scopus 로고    scopus 로고
    • Cell surface death receptor signaling in normal and cancer cells
    • Ozoren N, El-Deiry WS. Cell surface death receptor signaling in normal and cancer cells. Semin Cancer Biol. 2003;13:135-147.
    • (2003) Semin Cancer Biol , vol.13 , pp. 135-147
    • Ozoren, N.1    El-Deiry, W.S.2
  • 44
    • 1842865745 scopus 로고    scopus 로고
    • Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells
    • Kanzawa T, Germano IM, Komata T, et al. Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells. Cell Death Differ. 2004;11:448-457.
    • (2004) Cell Death Differ , vol.11 , pp. 448-457
    • Kanzawa, T.1    Germano, I.M.2    Komata, T.3
  • 45
    • 50549088118 scopus 로고    scopus 로고
    • Immunogenic anticancer chemotherapy as an emerging concept
    • Haynes NM, van der Most RG, Lake RA, et al. Immunogenic anticancer chemotherapy as an emerging concept. Curr Opin Immunol. 2008;20:545-557.
    • (2008) Curr Opin Immunol , vol.20 , pp. 545-557
    • Haynes, N.M.1    Van Der Most, R.G.2    Lake, R.A.3
  • 46
    • 37349062063 scopus 로고    scopus 로고
    • Decoding dangerous death: How cytotoxic chemotherapy invokes inflammation, immunity or nothing at all
    • van der Most RG, Currie AJ, Robinson BW, et al. Decoding dangerous death: how cytotoxic chemotherapy invokes inflammation, immunity or nothing at all. Cell Death Differ. 2008;15:13-20.
    • (2008) Cell Death Differ , vol.15 , pp. 13-20
    • Van Der Most, R.G.1    Currie, A.J.2    Robinson, B.W.3
  • 47
    • 18344375283 scopus 로고    scopus 로고
    • Immunotherapy and chemotherapy - A practical partnership
    • Lake RA, Robinson BW. Immunotherapy and chemotherapy - a practical partnership. Nat Rev Cancer. 2005;5:397-405.
    • (2005) Nat Rev Cancer , vol.5 , pp. 397-405
    • Lake, R.A.1    Robinson, B.W.2
  • 48
    • 85027939228 scopus 로고    scopus 로고
    • Contribution of the immune system to the chemotherapeutic response
    • McDonnell AM, Nowak AK, Lake RA. Contribution of the immune system to the chemotherapeutic response. Semin Immunopathol. 2011; 33:353-367.
    • (2011) Semin Immunopathol , vol.33 , pp. 353-367
    • McDonnell, A.M.1    Nowak, A.K.2    Lake, R.A.3
  • 49
    • 84866920006 scopus 로고    scopus 로고
    • Post-chemotherapy T-cell recovery is a marker of improved survival in patients with advanced thoracic malignancies
    • McCoy MJ, Lake RA, van der Most RG, et al. Post-chemotherapy T-cell recovery is a marker of improved survival in patients with advanced thoracic malignancies. Br J Cancer. 2012;107:1107-1115.
    • (2012) Br J Cancer , vol.107 , pp. 1107-1115
    • McCoy, M.J.1    Lake, R.A.2    Van Der Most, R.G.3
  • 50
    • 84864935156 scopus 로고    scopus 로고
    • Vaccines in non-small cell lung cancer: Rationale, combination strategies and update on clinical trials
    • De Pas T, Giovannini M, Rescigno M, et al. Vaccines in non-small cell lung cancer: rationale, combination strategies and update on clinical trials. Crit Rev Oncol Hematol. 2012;83:432-443.
    • (2012) Crit Rev Oncol Hematol , vol.83 , pp. 432-443
    • De Pas, T.1    Giovannini, M.2    Rescigno, M.3
  • 51
    • 80053369273 scopus 로고    scopus 로고
    • Lung cancer vaccines
    • Kelly RJ, Giaccone G. Lung cancer vaccines. Cancer J. 2011;17: 302-308.
    • (2011) Cancer J , vol.17 , pp. 302-308
    • Kelly, R.J.1    Giaccone, G.2
  • 52
    • 79955859969 scopus 로고    scopus 로고
    • Adjuvants for enhancing the immunogenicity of whole tumor cell vaccines
    • Chiang CL, Kandalaft LE, Coukos G. Adjuvants for enhancing the immunogenicity of whole tumor cell vaccines. Int Rev Immunol. 2011;30:150-182.
    • (2011) Int Rev Immunol , vol.30 , pp. 150-182
    • Chiang, C.L.1    Kandalaft, L.E.2    Coukos, G.3
  • 53
    • 79151482353 scopus 로고    scopus 로고
    • GM-CSF-secreting vaccines for solid tumors: Moving forward
    • Gupta R, Emens LA. GM-CSF-secreting vaccines for solid tumors: moving forward. Discov Med. 2010;10:52-60.
    • (2010) Discov Med , vol.10 , pp. 52-60
    • Gupta, R.1    Emens, L.A.2
  • 54
    • 84871574719 scopus 로고    scopus 로고
    • Beyond the standard of care: A review of novel immunotherapy trials for the treatment of lung cancer
    • Hall RD, Gray JE, Chiappori AA. Beyond the standard of care: a review of novel immunotherapy trials for the treatment of lung cancer. Cancer Control. 2013;20:22-31.
    • (2013) Cancer Control , vol.20 , pp. 22-31
    • Hall, R.D.1    Gray, J.E.2    Chiappori, A.A.3
  • 55
    • 84865567620 scopus 로고    scopus 로고
    • What future opportunities may immuno-oncology provide for improving the treatment of patients with lung cancer?
    • Reck M. What future opportunities may immuno-oncology provide for improving the treatment of patients with lung cancer? Ann Oncol. 2012;23(suppl 8):viii28-viii34.
    • (2012) Ann Oncol , vol.23 , Issue.SUPPL. 8
    • Reck, M.1
  • 56
    • 81255127285 scopus 로고    scopus 로고
    • Therapeutic vaccination with TG4010 and first-line chemotherapy in advanced non-small-cell lung cancer: A controlled phase 2B trial
    • Quoix E, Ramlau R, Westeel V, et al. Therapeutic vaccination with TG4010 and first-line chemotherapy in advanced non-small-cell lung cancer: a controlled phase 2B trial. Lancet Oncol. 2011;12:1125-1133.
    • (2011) Lancet Oncol , vol.12 , pp. 1125-1133
    • Quoix, E.1    Ramlau, R.2    Westeel, V.3
  • 57
    • 77953621768 scopus 로고    scopus 로고
    • Vaccines based on abnormal self-antigens as tumor-associated antigens: Immune regulation
    • Farkas AM, Finn OJ. Vaccines based on abnormal self-antigens as tumor-associated antigens: immune regulation. Semin Immunol. 2010; 22:125-131.
    • (2010) Semin Immunol , vol.22 , pp. 125-131
    • Farkas, A.M.1    Finn, O.J.2
  • 58
    • 84861731964 scopus 로고    scopus 로고
    • Vaccination therapy for non-small-cell lung cancer: Review of agents in phase III development
    • Decoster L, Wauters I, Vansteenkiste JF. Vaccination therapy for non-small-cell lung cancer: review of agents in phase III development. Ann Oncol. 2012;23:1387-1393.
    • (2012) Ann Oncol , vol.23 , pp. 1387-1393
    • Decoster, L.1    Wauters, I.2    Vansteenkiste, J.F.3
  • 59
    • 45549092607 scopus 로고    scopus 로고
    • Cancer immunology
    • Finn OJ. Cancer immunology. N Engl J Med. 2008;358:2704-2715.
    • (2008) N Engl J Med , vol.358 , pp. 2704-2715
    • Finn, O.J.1
  • 60
    • 84864380076 scopus 로고    scopus 로고
    • MAGE-A antigens as targets in tumour therapy
    • Meek DW, Marcar L. MAGE-A antigens as targets in tumour therapy. Cancer Lett. 2012;324:126-132.
    • (2012) Cancer Lett , vol.324 , pp. 126-132
    • Meek, D.W.1    Marcar, L.2
  • 61
    • 84862236855 scopus 로고    scopus 로고
    • Immune alterations and emerging immunotherapeutic approaches in lung cancer
    • Dasanu CA, Sethi N, Ahmed N. Immune alterations and emerging immunotherapeutic approaches in lung cancer. Expert Opin Biol Ther. 2012;12:923-937.
    • (2012) Expert Opin Biol Ther , vol.12 , pp. 923-937
    • Dasanu, C.A.1    Sethi, N.2    Ahmed, N.3
  • 62
    • 84867196968 scopus 로고    scopus 로고
    • Role of inflammatory dendritic cells in innate and adaptive immunity
    • Hespel C, Moser M. Role of inflammatory dendritic cells in innate and adaptive immunity. Eur J Immunol. 2012;42:2535-2543.
    • (2012) Eur J Immunol , vol.42 , pp. 2535-2543
    • Hespel, C.1    Moser, M.2
  • 63
    • 84865553173 scopus 로고    scopus 로고
    • Combination immunotherapy approaches
    • Drake CG. Combination immunotherapy approaches. Ann Oncol. 2012;23(suppl 8):viii41-viii6.
    • (2012) Ann Oncol , vol.23 , Issue.SUPPL. 8
    • Drake, C.G.1
  • 64
    • 71049153709 scopus 로고    scopus 로고
    • Cancer/testis (CT) antigens: Potential targets for immunotherapy
    • Caballero OL, Chen YT. Cancer/testis (CT) antigens: potential targets for immunotherapy. Cancer Sci. 2009;100:2014-2021.
    • (2009) Cancer Sci , vol.100 , pp. 2014-2021
    • Caballero, O.L.1    Chen, Y.T.2
  • 65
    • 0036894242 scopus 로고    scopus 로고
    • Tissue microarray evaluation of melanoma antigen e (MAGE) tumor-associated antigen expression: Potential indications for specific immunotherapy and prognostic relevance in squamous cell lung carcinoma
    • discussion 93
    • Bolli M, Kocher T, Adamina M, et al. Tissue microarray evaluation of melanoma antigen E (MAGE) tumor-associated antigen expression: potential indications for specific immunotherapy and prognostic relevance in squamous cell lung carcinoma. Ann Surg. 2002;236:785-793; discussion 93.
    • (2002) Ann Surg , vol.236 , pp. 785-793
    • Bolli, M.1    Kocher, T.2    Adamina, M.3
  • 66
    • 28144457350 scopus 로고    scopus 로고
    • Cancer-testis genes are coordinately expressed and are markers of poor outcome in non-small cell lung cancer
    • Gure AO, Chua R, Williamson B, et al. Cancer-testis genes are coordinately expressed and are markers of poor outcome in non-small cell lung cancer. Clin Cancer Res. 2005;11:8055-8062.
    • (2005) Clin Cancer Res , vol.11 , pp. 8055-8062
    • Gure, A.O.1    Chua, R.2    Williamson, B.3
  • 67
    • 0347364737 scopus 로고    scopus 로고
    • Melanoma associated antigen (MAGE)-A3 expression in Stages I and II non-small cell lung cancer: Results of a multi-center study
    • Sienel W, Varwerk C, Linder A, et al. Melanoma associated antigen (MAGE)-A3 expression in Stages I and II non-small cell lung cancer: results of a multi-center study. Eur J Cardiothorac Surg. 2004;25: 131-134.
    • (2004) Eur J Cardiothorac Surg , vol.25 , pp. 131-134
    • Sienel, W.1    Varwerk, C.2    Linder, A.3
  • 68
    • 84872600972 scopus 로고    scopus 로고
    • Patient and tumor characteristics impacting on MAGE-A3 expression: Screening data from the MAGRIT phase III trial
    • (abstract M021.08)
    • Kim JH, Zo J, Nakayama H. Patient and tumor characteristics impacting on MAGE-A3 expression: screening data from the MAGRIT phase III trial. J Thorac Oncol. 2011;6:S662 (abstract M021.08).
    • (2011) J Thorac Oncol , vol.6
    • Kim, J.H.1    Zo, J.2    Nakayama, H.3
  • 69
    • 10744229438 scopus 로고    scopus 로고
    • Vaccine-induced CD4+ T cell responses to MAGE-3 protein in lung cancer patients
    • Atanackovic D, Altorki NK, Stockert E, et al. Vaccine-induced CD4+ T cell responses to MAGE-3 protein in lung cancer patients. J Immunol. 2004;172:3289-3296.
    • (2004) J Immunol , vol.172 , pp. 3289-3296
    • Atanackovic, D.1    Altorki, N.K.2    Stockert, E.3
  • 70
    • 74049130382 scopus 로고    scopus 로고
    • Phase II randomized study of MAGE-A3 immunotherapy as adjuvant therapy in stage IB/II nonsmall cell lung cancer (NSCLC): 44 month follow-up, humoral and cellular immune response data
    • (abstract 1480)
    • Vansteenkiste J, Zielinski M, Linder A. Phase II randomized study of MAGE-A3 immunotherapy as adjuvant therapy in stage IB/II nonsmall cell lung cancer (NSCLC): 44 month follow-up, humoral and cellular immune response data. J Thorac Oncol. 2008;3:S55-S56 (abstract 1480).
    • (2008) J Thorac Oncol , vol.3
    • Vansteenkiste, J.1    Zielinski, M.2    Linder, A.3
  • 71
    • 77958012775 scopus 로고    scopus 로고
    • Gene signature in melanoma associated with clinical activity: A potential clue to unlock cancer immunotherapy
    • Gajewski TF, Louahed J, Brichard VG. Gene signature in melanoma associated with clinical activity: a potential clue to unlock cancer immunotherapy. Cancer J. 2010;16:399-403.
    • (2010) Cancer J , vol.16 , pp. 399-403
    • Gajewski, T.F.1    Louahed, J.2    Brichard, V.G.3
  • 72
    • 0025029968 scopus 로고
    • Molecular cloning and expression of human tumor-associated polymorphic epithelial mucin
    • Gendler SJ, Lancaster CA, Taylor-Papadimitriou J, et al. Molecular cloning and expression of human tumor-associated polymorphic epithelial mucin. J Biol Chem. 1990;265:15286-15293.
    • (1990) J Biol Chem , vol.265 , pp. 15286-15293
    • Gendler, S.J.1    Lancaster, C.A.2    Taylor-Papadimitriou, J.3
  • 73
    • 34547661985 scopus 로고    scopus 로고
    • L-BLP25: A peptide vaccine strategy in non small cell lung cancer
    • Sangha R, Butts C. L-BLP25: a peptide vaccine strategy in non small cell lung cancer. Clin Cancer Res. 2007;13:s4652-s4.
    • (2007) Clin Cancer Res , vol.13
    • Sangha, R.1    Butts, C.2
  • 74
    • 10744220453 scopus 로고    scopus 로고
    • Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents
    • Ren J, Agata N, Chen D, et al. Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents. Cancer Cell. 2004;5:163-175.
    • (2004) Cancer Cell , vol.5 , pp. 163-175
    • Ren, J.1    Agata, N.2    Chen, D.3
  • 75
    • 0029743771 scopus 로고    scopus 로고
    • Pre-immunotherapy serum CA27.29 (MUC-1) mucin level and CD69+ lymphocytes correlate with effects of theratope sialyl-Tn-KLH cancer vaccine in active specific immunotherapy
    • Reddish MA, MacLean GD, Poppema S, et al. Pre-immunotherapy serum CA27.29 (MUC-1) mucin level and CD69+ lymphocytes correlate with effects of theratope sialyl-Tn-KLH cancer vaccine in active specific immunotherapy. Cancer Immunol Immunother. 1996;42: 303-309.
    • (1996) Cancer Immunol Immunother , vol.42 , pp. 303-309
    • Reddish, M.A.1    MacLean, G.D.2    Poppema, S.3
  • 76
    • 80054742888 scopus 로고    scopus 로고
    • Updated survival analysis in patients with stage IIIB or IV non-small-cell lung cancer receiving BLP25 liposome vaccine (L-BLP25): Phase IIB randomized, multicenter, open-label trial
    • Butts C, Maksymiuk A, Goss G, et al. Updated survival analysis in patients with stage IIIB or IV non-small-cell lung cancer receiving BLP25 liposome vaccine (L-BLP25): phase IIB randomized, multicenter, open-label trial. J Cancer Res Clin Oncol. 2011;137: 1337-1342.
    • (2011) J Cancer Res Clin Oncol , vol.137 , pp. 1337-1342
    • Butts, C.1    Maksymiuk, A.2    Goss, G.3
  • 77
    • 0034789572 scopus 로고    scopus 로고
    • Phase I study of the BLP25 (MUC1 peptide) liposomal vaccine for active specific immunotherapy in stage IIIB/IV non-small-cell lung cancer
    • Palmer M, Parker J, Modi S, et al. Phase I study of the BLP25 (MUC1 peptide) liposomal vaccine for active specific immunotherapy in stage IIIB/IV non-small-cell lung cancer. Clin Lung Cancer. 2001;3:49-57.
    • (2001) Clin Lung Cancer , vol.3 , pp. 49-57
    • Palmer, M.1    Parker, J.2    Modi, S.3
  • 78
    • 79955862560 scopus 로고    scopus 로고
    • Safety of BLP25 liposome vaccine (L-BLP25) in Japanese patients with unresectable stage III NSCLC after primary chemoradiotherapy: Preliminary results from a phase I/II study
    • Ohyanagi F, Horai T, Sekine I, et al. Safety of BLP25 liposome vaccine (L-BLP25) in Japanese patients with unresectable stage III NSCLC after primary chemoradiotherapy: preliminary results from a phase I/II study. Jpn J Clin Oncol. 2011;41:718-722.
    • (2011) Jpn J Clin Oncol , vol.41 , pp. 718-722
    • Ohyanagi, F.1    Horai, T.2    Sekine, I.3
  • 79
    • 50349090322 scopus 로고    scopus 로고
    • A phase II study of Tg4010 (Mva-Muc1-Il2) in association with chemotherapy in patients with stage III/IV non-small cell lung cancer
    • Ramlau R, Quoix E, Rolski J, et al. A phase II study of Tg4010 (Mva-Muc1-Il2) in association with chemotherapy in patients with stage III/IV non-small cell lung cancer. J Thorac Oncol. 2008;3:735-744.
    • (2008) J Thorac Oncol , vol.3 , pp. 735-744
    • Ramlau, R.1    Quoix, E.2    Rolski, J.3
  • 80
    • 77952896646 scopus 로고    scopus 로고
    • TGFbeta signalling: A complex web in cancer progression
    • Ikushima H, Miyazono K. TGFbeta signalling: a complex web in cancer progression. Nat Rev Cancer. 2010;10:415-424.
    • (2010) Nat Rev Cancer , vol.10 , pp. 415-424
    • Ikushima, H.1    Miyazono, K.2
  • 81
    • 0033229730 scopus 로고    scopus 로고
    • Plasma transforming growth factor-beta1 level before radiotherapy correlates with long term outcome of patients with lung carcinoma
    • Kong F, Jirtle RL, Huang DH, et al. Plasma transforming growth factor-beta1 level before radiotherapy correlates with long term outcome of patients with lung carcinoma. Cancer. 1999;86:1712-1719.
    • (1999) Cancer , vol.86 , pp. 1712-1719
    • Kong, F.1    Jirtle, R.L.2    Huang, D.H.3
  • 82
    • 33750586798 scopus 로고    scopus 로고
    • Phase II study of belagenpumatucel-L, a transforming growth factor beta-2 antisense gene-modified allogeneic tumor cell vaccine in non-small-cell lung cancer
    • Nemunaitis J, Dillman RO, Schwarzenberger PO, et al. Phase II study of belagenpumatucel-L, a transforming growth factor beta-2 antisense gene-modified allogeneic tumor cell vaccine in non-small-cell lung cancer. J Clin Oncol. 2006;24:4721-4730.
    • (2006) J Clin Oncol , vol.24 , pp. 4721-4730
    • Nemunaitis, J.1    Dillman, R.O.2    Schwarzenberger, P.O.3
  • 83
    • 67651091694 scopus 로고    scopus 로고
    • Phase II trial of Belagenpumatucel-L, a TGF-beta2 antisense gene modified allogeneic tumor vaccine in advanced non small cell lung cancer (NSCLC) patients
    • Nemunaitis J, Nemunaitis M, Senzer N, et al. Phase II trial of Belagenpumatucel-L, a TGF-beta2 antisense gene modified allogeneic tumor vaccine in advanced non small cell lung cancer (NSCLC) patients. Cancer Gene Ther. 2009;16:620-624.
    • (2009) Cancer Gene Ther , vol.16 , pp. 620-624
    • Nemunaitis, J.1    Nemunaitis, M.2    Senzer, N.3
  • 84
    • 0035182192 scopus 로고    scopus 로고
    • Efficient identification of novel HLA-A(*)0201-presented cytotoxic T lymphocyte epitopes in the widely expressed tumor antigen PRAME by proteasome-mediated digestion analysis
    • Kessler JH, Beekman NJ, Bres-Vloemans SA, et al. Efficient identification of novel HLA-A(*)0201-presented cytotoxic T lymphocyte epitopes in the widely expressed tumor antigen PRAME by proteasome-mediated digestion analysis. J Exp Med. 2001;193:73-88.
    • (2001) J Exp Med , vol.193 , pp. 73-88
    • Kessler, J.H.1    Beekman, N.J.2    Bres-Vloemans, S.A.3
  • 85
    • 0030962059 scopus 로고    scopus 로고
    • Characterization of an antigen that is recognized on a melanoma showing partial HLA loss by CTL expressing an NK inhibitory receptor
    • Ikeda H, Lethe B, Lehmann F, et al. Characterization of an antigen that is recognized on a melanoma showing partial HLA loss by CTL expressing an NK inhibitory receptor. Immunity. 1997;6:199-208.
    • (1997) Immunity , vol.6 , pp. 199-208
    • Ikeda, H.1    Lethe, B.2    Lehmann, F.3
  • 86
    • 72549094017 scopus 로고    scopus 로고
    • Identification of genes associated with non-small-cell lung cancer promotion and progression
    • Bankovic J, Stojsic J, Jovanovic D, et al. Identification of genes associated with non-small-cell lung cancer promotion and progression. Lung Cancer. 2010;67:151-159.
    • (2010) Lung Cancer , vol.67 , pp. 151-159
    • Bankovic, J.1    Stojsic, J.2    Jovanovic, D.3
  • 87
    • 25144503301 scopus 로고    scopus 로고
    • The human tumor antigen PRAME is a dominant repressor of retinoic acid receptor signaling
    • Epping MT, Wang L, Edel MJ, et al. The human tumor antigen PRAME is a dominant repressor of retinoic acid receptor signaling. Cell. 2005;122:835-847.
    • (2005) Cell , vol.122 , pp. 835-847
    • Epping, M.T.1    Wang, L.2    Edel, M.J.3
  • 88
    • 0031775979 scopus 로고    scopus 로고
    • A novel cancer vaccine composed of human-recombinant epidermal growth factor linked to a carrier protein: Report of a pilot clinical trial
    • Gonzalez G, Crombet T, Catala M, et al. A novel cancer vaccine composed of human-recombinant epidermal growth factor linked to a carrier protein: report of a pilot clinical trial. Ann Oncol. 1998;9: 431-435.
    • (1998) Ann Oncol , vol.9 , pp. 431-435
    • Gonzalez, G.1    Crombet, T.2    Catala, M.3
  • 89
    • 41149159650 scopus 로고    scopus 로고
    • Phase II randomized controlled trial of an epidermal growth factor vaccine in advanced non-small-cell lung cancer
    • Neninger Vinageras E, de la Torre A, Osorio Rodriguez M, et al. Phase II randomized controlled trial of an epidermal growth factor vaccine in advanced non-small-cell lung cancer. J Clin Oncol. 2008;26:1452-1458.
    • (2008) J Clin Oncol , vol.26 , pp. 1452-1458
    • Neninger Vinageras, E.1    De La Torre, A.2    Osorio Rodriguez, M.3
  • 90
    • 0037441842 scopus 로고    scopus 로고
    • Vaccination with irradiated autologous tumor cells engineered to secrete granulocyte-macrophage colony-stimulating factor augments antitumor immunity in some patients with metastatic non-small-cell lung carcinoma
    • Salgia R, Lynch T, Skarin A, et al. Vaccination with irradiated autologous tumor cells engineered to secrete granulocyte-macrophage colony-stimulating factor augments antitumor immunity in some patients with metastatic non-small-cell lung carcinoma. J Clin Oncol. 2003;21:624-630.
    • (2003) J Clin Oncol , vol.21 , pp. 624-630
    • Salgia, R.1    Lynch, T.2    Skarin, A.3
  • 91
    • 10744229445 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor gene-modified autologous tumor vaccines in non-small-cell lung cancer
    • Nemunaitis J, Sterman D, Jablons D, et al. Granulocyte-macrophage colony-stimulating factor gene-modified autologous tumor vaccines in non-small-cell lung cancer. J Natl Cancer Inst. 2004;96:326-331.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 326-331
    • Nemunaitis, J.1    Sterman, D.2    Jablons, D.3
  • 92
    • 84863911486 scopus 로고    scopus 로고
    • Ipilimumab in combination with paclitaxel and carboplatin as first-line treatment in stage IIIB/IV non-small-cell lung cancer: Results from a randomized, double-blind, multicenter phase II study
    • Lynch TJ, Bondarenko I, Luft A, et al. Ipilimumab in combination with paclitaxel and carboplatin as first-line treatment in stage IIIB/IV non-small-cell lung cancer: results from a randomized, double-blind, multicenter phase II study. J Clin Oncol. 2012;30:2046-2054.
    • (2012) J Clin Oncol , vol.30 , pp. 2046-2054
    • Lynch, T.J.1    Bondarenko, I.2    Luft, A.3
  • 93
    • 76749084659 scopus 로고    scopus 로고
    • Randomized phase II clinical trial comparing tremelimumab (CP-675,206) with best supportive care (BSC) following first-line platinum-based therapy in patients (pts) with advanced non-small cell lung cancer (NSCLC)
    • abstract 8071
    • Zatloukal P, Heo DS, Park K, et al. Randomized phase II clinical trial comparing tremelimumab (CP-675,206) with best supportive care (BSC) following first-line platinum-based therapy in patients (pts) with advanced non-small cell lung cancer (NSCLC). J Clin Oncol. 2009;27: (suppl; abstract 8071).
    • (2009) J Clin Oncol , vol.27 , Issue.SUPPL.
    • Zatloukal, P.1    Heo, D.S.2    Park, K.3
  • 94
    • 84862859820 scopus 로고    scopus 로고
    • Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
    • Topalian SL, Hodi FS, Brahmer JR, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med. 2012;366: 2443-2454.
    • (2012) N Engl J Med , vol.366 , pp. 2443-2454
    • Topalian, S.L.1    Hodi, F.S.2    Brahmer, J.R.3
  • 95
    • 84862903106 scopus 로고    scopus 로고
    • Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
    • Brahmer JR, Tykodi SS, Chow LQ, et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med. 2012;366:2455-2465.
    • (2012) N Engl J Med , vol.366 , pp. 2455-2465
    • Brahmer, J.R.1    Tykodi, S.S.2    Chow, L.Q.3
  • 96
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • Akira S, Takeda K. Toll-like receptor signalling. Nat Rev Immunol. 2004;4:499-511.
    • (2004) Nat Rev Immunol , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 97
    • 25444470242 scopus 로고    scopus 로고
    • Human lung cancer cells express functionally active Toll-like receptor 9
    • Droemann D, Albrecht D, Gerdes J, et al. Human lung cancer cells express functionally active Toll-like receptor 9. Respir Res. 2005;6:1.
    • (2005) Respir Res , vol.6 , pp. 1
    • Droemann, D.1    Albrecht, D.2    Gerdes, J.3
  • 98
    • 33745946911 scopus 로고    scopus 로고
    • Therapeutic potential of Toll-like receptor 9 activation
    • Krieg AM. Therapeutic potential of Toll-like receptor 9 activation. Nat Rev Drug Discov. 2006;5:471-484.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 471-484
    • Krieg, A.M.1
  • 99
    • 50549084485 scopus 로고    scopus 로고
    • Randomized phase II trial of a Toll-like receptor 9 agonist oligodeoxynucleotide, PF-3512676, in combination with first-line taxane plus platinum chemotherapy for advanced-stage non-small-cell lung cancer
    • Manegold C, Gravenor D, Woytowitz D, et al. Randomized phase II trial of a Toll-like receptor 9 agonist oligodeoxynucleotide, PF-3512676, in combination with first-line taxane plus platinum chemotherapy for advanced-stage non-small-cell lung cancer. J Clin Oncol. 2008;26:3979-3986.
    • (2008) J Clin Oncol , vol.26 , pp. 3979-3986
    • Manegold, C.1    Gravenor, D.2    Woytowitz, D.3
  • 100
    • 84855184648 scopus 로고    scopus 로고
    • A phase III randomized study of gemcitabine and cisplatin with or without PF-3512676 (TLR9 agonist) as first-line treatment of advanced non-small-cell lung cancer
    • Manegold C, van Zandwijk N, Szczesna A, et al. A phase III randomized study of gemcitabine and cisplatin with or without PF-3512676 (TLR9 agonist) as first-line treatment of advanced non-small-cell lung cancer. Ann Oncol. 2012;23:72-77.
    • (2012) Ann Oncol , vol.23 , pp. 72-77
    • Manegold, C.1    Van Zandwijk, N.2    Szczesna, A.3
  • 101
    • 79960110662 scopus 로고    scopus 로고
    • Randomized phase III trial of paclitaxel/carboplatin with or without PF-3512676 (Toll-like receptor 9 agonist) as first-line treatment for advanced non-small-cell lung cancer
    • Hirsh V, Paz-Ares L, Boyer M, et al. Randomized phase III trial of paclitaxel/carboplatin with or without PF-3512676 (Toll-like receptor 9 agonist) as first-line treatment for advanced non-small-cell lung cancer. J Clin Oncol. 2011;29:2667-2674.
    • (2011) J Clin Oncol , vol.29 , pp. 2667-2674
    • Hirsh, V.1    Paz-Ares, L.2    Boyer, M.3
  • 102
    • 80755143443 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled phase II study of single-agent oral talactoferrin in patients with locally advanced or metastatic non-small-cell lung cancer that progressed after chemotherapy
    • Parikh PM, Vaid A, Advani SH, et al. Randomized, double-blind, placebo-controlled phase II study of single-agent oral talactoferrin in patients with locally advanced or metastatic non-small-cell lung cancer that progressed after chemotherapy. J Clin Oncol. 2011;29:4129-4136.
    • (2011) J Clin Oncol , vol.29 , pp. 4129-4136
    • Parikh, P.M.1    Vaid, A.2    Advani, S.H.3
  • 103
    • 79958111407 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled, phase II study of oral talactoferrin in combination with carboplatin and paclitaxel in previously untreated locally advanced or metastatic non-small cell lung cancer
    • Digumarti R, Wang Y, Raman G, et al. A randomized, double-blind, placebo-controlled, phase II study of oral talactoferrin in combination with carboplatin and paclitaxel in previously untreated locally advanced or metastatic non-small cell lung cancer. J Thorac Oncol. 2011; 6:1098-1103.
    • (2011) J Thorac Oncol , vol.6 , pp. 1098-1103
    • Digumarti, R.1    Wang, Y.2    Raman, G.3
  • 106
    • 33846057130 scopus 로고    scopus 로고
    • Calreticulin exposure dictates the immunogenicity of cancer cell death
    • Obeid M, Tesniere A, Ghiringhelli F, et al. Calreticulin exposure dictates the immunogenicity of cancer cell death. Nat Med. 2007;13: 54-61.
    • (2007) Nat Med , vol.13 , pp. 54-61
    • Obeid, M.1    Tesniere, A.2    Ghiringhelli, F.3
  • 107
    • 0038326676 scopus 로고    scopus 로고
    • Induction of tumor cell apoptosis in vivo increases tumor antigen cross-presentation, crosspriming rather than cross-tolerizing host tumor-specific CD8 T cells
    • Nowak AK, Lake RA, Marzo AL, et al. Induction of tumor cell apoptosis in vivo increases tumor antigen cross-presentation, crosspriming rather than cross-tolerizing host tumor-specific CD8 T cells. J Immunol. 2003;170:4905-4913.
    • (2003) J Immunol , vol.170 , pp. 4905-4913
    • Nowak, A.K.1    Lake, R.A.2    Marzo, A.L.3
  • 108
    • 34948820602 scopus 로고    scopus 로고
    • Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy
    • Apetoh L, Ghiringhelli F, Tesniere A, et al. Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy. Nat Med. 2007;13:1050-1059.
    • (2007) Nat Med , vol.13 , pp. 1050-1059
    • Apetoh, L.1    Ghiringhelli, F.2    Tesniere, A.3
  • 109
    • 51549088023 scopus 로고    scopus 로고
    • Radiation-induced CXCL16 release by breast cancer cells attracts effector T cells
    • Matsumura S, Wang B, Kawashima N, et al. Radiation-induced CXCL16 release by breast cancer cells attracts effector T cells. J Immunol. 2008;181:3099-3107.
    • (2008) J Immunol , vol.181 , pp. 3099-3107
    • Matsumura, S.1    Wang, B.2    Kawashima, N.3
  • 110
    • 0029803150 scopus 로고    scopus 로고
    • Cell adhesion molecules mediate radiation-induced leukocyte adhesion to the vascular endothelium
    • Hallahan D, Kuchibhotla J, Wyble C. Cell adhesion molecules mediate radiation-induced leukocyte adhesion to the vascular endothelium. Cancer Res. 1996;56:5150-5155.
    • (1996) Cancer Res , vol.56 , pp. 5150-5155
    • Hallahan, D.1    Kuchibhotla, J.2    Wyble, C.3
  • 111
    • 0042591416 scopus 로고    scopus 로고
    • Synergy between chemotherapy and immunotherapy in the treatment of established murine solid tumors
    • Nowak AK, Robinson BW, Lake RA. Synergy between chemotherapy and immunotherapy in the treatment of established murine solid tumors. Cancer Res. 2003;63:4490-4496.
    • (2003) Cancer Res , vol.63 , pp. 4490-4496
    • Nowak, A.K.1    Robinson, B.W.2    Lake, R.A.3
  • 112
    • 0034796870 scopus 로고    scopus 로고
    • Development of tumorinfiltrating lymphocytes in breast cancer after neoadjuvant paclitaxel chemotherapy
    • Demaria S, Volm MD, Shapiro RL, et al. Development of tumorinfiltrating lymphocytes in breast cancer after neoadjuvant paclitaxel chemotherapy. Clin Cancer Res. 2001;7:3025-3030.
    • (2001) Clin Cancer Res , vol.7 , pp. 3025-3030
    • Demaria, S.1    Volm, M.D.2    Shapiro, R.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.