메뉴 건너뛰기




Volumn 2 AUG, Issue , 2012, Pages

Effects of ionizing radiation on the immune system with special emphasis on the interaction of dendritic and T cells

Author keywords

Dendritic cells; Immune system; Ionizing radiation; Low dose; T cells

Indexed keywords

B7 ANTIGEN; CD40 ANTIGEN; CD86 ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 12; STAT PROTEIN; T6 ANTIGEN;

EID: 84880101488     PISSN: None     EISSN: 2234943X     Source Type: Journal    
DOI: 10.3389/fonc.2012.00102     Document Type: Review
Times cited : (122)

References (94)
  • 1
    • 75649111947 scopus 로고    scopus 로고
    • Calcifying tendonitis of the shoulder joint: predictive value of pretreatment sonography for the response to low-dose radiotherapy
    • Adamietz, B., Schulz-Wendtland, R., Alibek, S., Uder, M., Sauer, R., Ott, O., and Keilholz, L. (2010). Calcifying tendonitis of the shoulder joint: predictive value of pretreatment sonography for the response to low-dose radiotherapy. Strahlenther. Onkol. 186, 18-23.
    • (2010) Strahlenther. Onkol. , vol.186 , pp. 18-23
    • Adamietz, B.1    Schulz-Wendtland, R.2    Alibek, S.3    Uder, M.4    Sauer, R.5    Ott, O.6    Keilholz, L.7
  • 2
    • 3543053363 scopus 로고    scopus 로고
    • Immature dendritic cells phagocytose apoptotic cells via alphavbeta5 and CD36, and cross-present antigens to cytotoxic T lymphocytes
    • Albert, M. L., Pearce, S. F., Francisco, L. M., Sauter, B., Roy, P., Silverstein, R. L., and Bhardwaj, N. (1998). Immature dendritic cells phagocytose apoptotic cells via alphavbeta5 and CD36, and cross-present antigens to cytotoxic T lymphocytes. J. Exp. Med. 188, 1359-1368.
    • (1998) J. Exp. Med. , vol.188 , pp. 1359-1368
    • Albert, M.L.1    Pearce, S.F.2    Francisco, L.M.3    Sauter, B.4    Roy, P.5    Silverstein, R.L.6    Bhardwaj, N.7
  • 3
    • 51349132659 scopus 로고    scopus 로고
    • Mechanisms and consequences of dendritic cell migration
    • Alvarez, D., Vollmann, E. H., and von Andrian, U. H. (2008). Mechanisms and consequences of dendritic cell migration. Immunity 29, 325-342.
    • (2008) Immunity , vol.29 , pp. 325-342
    • Alvarez, D.1    Vollmann, E.H.2    von Andrian, U.H.3
  • 4
    • 45849102067 scopus 로고    scopus 로고
    • Functional genomics and a new era in radiation biology and oncology
    • Amundson, S. A. (2008). Functional genomics and a new era in radiation biology and oncology. Bioscience 58, 491-500.
    • (2008) Bioscience , vol.58 , pp. 491-500
    • Amundson, S.A.1
  • 5
    • 0017257355 scopus 로고
    • Ionizing radiation and the immune response
    • Anderson, R. E., and Warner, N. L. (1976). Ionizing radiation and the immune response. Adv. Immunol. 24, 215-335.
    • (1976) Adv. Immunol. , vol.24 , pp. 215-335
    • Anderson, R.E.1    Warner, N.L.2
  • 6
    • 0031938507 scopus 로고    scopus 로고
    • Generation of dendritic cells from peripheral blood adherent cells in medium with human serum
    • Anton, D., Dabadghao, S., Palucka, K., Holm, G., and Yi, Q. (1998). Generation of dendritic cells from peripheral blood adherent cells in medium with human serum. Scand. J. Immunol. 47, 116-121.
    • (1998) Scand. J. Immunol. , vol.47 , pp. 116-121
    • Anton, D.1    Dabadghao, S.2    Palucka, K.3    Holm, G.4    Yi, Q.5
  • 8
    • 77951692771 scopus 로고    scopus 로고
    • Plasticity in programming of effector and memory CD8 T-cell formation
    • Arens, R., and Schoenberger, S. P. (2010). Plasticity in programming of effector and memory CD8 T-cell formation. Immunol. Rev. 235, 190-205.
    • (2010) Immunol. Rev. , vol.235 , pp. 190-205
    • Arens, R.1    Schoenberger, S.P.2
  • 9
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau, J., and Steinman, R. M. (1998). Dendritic cells and the control of immunity. Nature 392, 245-252.
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 10
    • 84863264554 scopus 로고    scopus 로고
    • Cancer and radiation therapy: current advances and future directions
    • Baskar, R., Lee, K. A., Yeo, R., and Yeoh, K. W. U. (2012). Cancer and radiation therapy: current advances and future directions. Int. J. Med. Sci. 9, 193-199.
    • (2012) Int. J. Med. Sci. , vol.9 , pp. 193-199
    • Baskar, R.1    Lee, K.A.2    Yeo, R.3    Yeoh, K.W.U.4
  • 12
    • 79956084444 scopus 로고    scopus 로고
    • Understand memory, design better vaccines
    • Bevan, M. J. (2011). Understand memory, design better vaccines. Nat. Immunol. 12, 463-465.
    • (2011) Nat. Immunol. , vol.12 , pp. 463-465
    • Bevan, M.J.1
  • 13
    • 0035087883 scopus 로고    scopus 로고
    • Deceleration of carcinogenic potential by adaptation with low dose gamma irradiation
    • Bhattacharjee, D., and Ito, A. (2001). Deceleration of carcinogenic potential by adaptation with low dose gamma irradiation. In Vivo 15, 87-92.
    • (2001) In Vivo , vol.15 , pp. 87-92
    • Bhattacharjee, D.1    Ito, A.2
  • 15
    • 1242270633 scopus 로고    scopus 로고
    • Gamma irradiation of human dendritic cells influences proliferation and cytokine profile of T cells in autologous mixed lymphocyte reaction
    • Cao, M. D., Chen, Z. D., and Xing, Y. (2004). Gamma irradiation of human dendritic cells influences proliferation and cytokine profile of T cells in autologous mixed lymphocyte reaction. Cell Biol. Int. 28, 223-228.
    • (2004) Cell Biol. Int. , vol.28 , pp. 223-228
    • Cao, M.D.1    Chen, Z.D.2    Xing, Y.3
  • 16
    • 0027340164 scopus 로고
    • A TH1 → TH2 switch is a critical step in the etiology of HIV infection
    • Clerici, M., and Shearer, G. M. (1993). A TH1 → TH2 switch is a critical step in the etiology of HIV infection. Immunol. Today 14, 107-111.
    • (1993) Immunol. Today , vol.14 , pp. 107-111
    • Clerici, M.1    Shearer, G.M.2
  • 19
    • 12244252335 scopus 로고    scopus 로고
    • Immune-mediated inhibition of metastases after treatment with local radiation and CTLA-4 blockade in a mouse model of breast cancer
    • Demaria, S., Kawashima, N., Yang, A. M., Devitt, M. L., Babb, J. S., Allison, J. P., and Formenti, S. C. (2005b). Immune-mediated inhibition of metastases after treatment with local radiation and CTLA-4 blockade in a mouse model of breast cancer. Clin. Cancer Res. 11(Pt 1), 728-734.
    • (2005) Clin. Cancer Res. , vol.11 , Issue.PART 1 , pp. 728-734
    • Demaria, S.1    Kawashima, N.2    Yang, A.M.3    Devitt, M.L.4    Babb, J.S.5    Allison, J.P.6    Formenti, S.C.7
  • 21
    • 2942534196 scopus 로고    scopus 로고
    • Recent progress in immunotherapy for malignant glioma: treatment strategies and results from clinical trials
    • Ehtesham, M., Black, K. L., and Yu, J. S. (2004). Recent progress in immunotherapy for malignant glioma: treatment strategies and results from clinical trials. Cancer Control 11, 192-207.
    • (2004) Cancer Control , vol.11 , pp. 192-207
    • Ehtesham, M.1    Black, K.L.2    Yu, J.S.3
  • 22
    • 0035889125 scopus 로고    scopus 로고
    • Calcium signaling inhibits interleukin-12 production and activates CD83(+) dendritic cells that induce Th2 cell development
    • Faries, M. B., Bedrosian, I., Xu, S., Koski, G., Roros, J. G., Moise, M. A., Nguyen, H. Q., Engels, F. H., Cohen, P. A., and Czerniecki, B. J. (2001). Calcium signaling inhibits interleukin-12 production and activates CD83(+) dendritic cells that induce Th2 cell development. Blood 98, 2489-2497.
    • (2001) Blood , vol.98 , pp. 2489-2497
    • Faries, M.B.1    Bedrosian, I.2    Xu, S.3    Koski, G.4    Roros, J.G.5    Moise, M.A.6    Nguyen, H.Q.7    Engels, F.H.8    Cohen, P.A.9    Czerniecki, B.J.10
  • 23
    • 77952559812 scopus 로고    scopus 로고
    • Immunological aspects of local radiotherapy: clinical relevance
    • Formenti, S. C. (2010). Immunological aspects of local radiotherapy: clinical relevance. Discov. Med. 9, 119-124.
    • (2010) Discov. Med. , vol.9 , pp. 119-124
    • Formenti, S.C.1
  • 24
    • 20444431560 scopus 로고    scopus 로고
    • Hsp70 surface-positive tumor-exosomes stimulate migratory and cytolytic activity of NK cells
    • Gastpar, R., Gehrmann, M., Bausero, M., Asea, A., Gross, C., Schroeder, J., and Multhoff, G. (2005). Hsp70 surface-positive tumor-exosomes stimulate migratory and cytolytic activity of NK cells. Cancer Res. 65, 5238-5247.
    • (2005) Cancer Res. , vol.65 , pp. 5238-5247
    • Gastpar, R.1    Gehrmann, M.2    Bausero, M.3    Asea, A.4    Gross, C.5    Schroeder, J.6    Multhoff, G.7
  • 25
    • 26844563179 scopus 로고    scopus 로고
    • Medical management of radiological casualties
    • Goans, R. E., and Waselenko, J. K. (2005). Medical management of radiological casualties. Health Phys. 89, 505-512.
    • (2005) Health Phys. , vol.89 , pp. 505-512
    • Goans, R.E.1    Waselenko, J.K.2
  • 26
    • 4344652144 scopus 로고    scopus 로고
    • Diminished cellular and humoral immunity in workers occupationally exposed to low levels of ionizing radiation
    • Godekmerdan, A., Ozden, M., Ayar, A., Gursu, M. F., Ozan, A. T., and Serhatlioglu, S. (2004). Diminished cellular and humoral immunity in workers occupationally exposed to low levels of ionizing radiation. Arch. Med. Res. 35, 324-328.
    • (2004) Arch. Med. Res. , vol.35 , pp. 324-328
    • Godekmerdan, A.1    Ozden, M.2    Ayar, A.3    Gursu, M.F.4    Ozan, A.T.5    Serhatlioglu, S.6
  • 27
    • 64949143960 scopus 로고    scopus 로고
    • Low dose, low dose rate photon radiation modifies distribution and gene expression in CD4+ T cells
    • Gridley, D. S., Rizvi, A., Luo-Owen, X., Makinde, A. Y., and Pecaut, M. J. (2009). Low dose, low dose rate photon radiation modifies distribution and gene expression in CD4+ T cells. J. Radiat. Res. 50, 139-150.
    • (2009) J. Radiat. Res. , vol.50 , pp. 139-150
    • Gridley, D.S.1    Rizvi, A.2    Luo-Owen, X.3    Makinde, A.Y.4    Pecaut, M.J.5
  • 29
    • 1842837930 scopus 로고    scopus 로고
    • Gamma irradiation-reduced IFN-gamma expression, STAT1 signals, and cell-mediated immunity
    • Han, S. K., Song, J. Y., Yun, Y. S., and Yi, S. Y. (2002). Gamma irradiation-reduced IFN-gamma expression, STAT1 signals, and cell-mediated immunity. J. Biochem. Mol. Biol. 35, 583-589.
    • (2002) J. Biochem. Mol. Biol. , vol.35 , pp. 583-589
    • Han, S.K.1    Song, J.Y.2    Yun, Y.S.3    Yi, S.Y.4
  • 30
    • 33750043209 scopus 로고    scopus 로고
    • Effect of gamma radiation on cytokine expression and cytokine-receptor mediated STAT activation
    • Han, S. K., Song, J. Y., Yun, Y. S., and Yi, S. Y. (2006). Effect of gamma radiation on cytokine expression and cytokine-receptor mediated STAT activation. Int. J. Radiat. Biol. 82, 686-697.
    • (2006) Int. J. Radiat. Biol. , vol.82 , pp. 686-697
    • Han, S.K.1    Song, J.Y.2    Yun, Y.S.3    Yi, S.Y.4
  • 31
    • 0033051757 scopus 로고    scopus 로고
    • The suppression of metastases and the change in host immune response after low-dose total-body irradiation in tumor-bearing rats
    • Hashimoto, S., Shirato, H., Hosokawa, M., Nishioka, T., Kuramitsu, Y., Matushita, K., Kobayashi, M., and Miyasaka, K. (1999). The suppression of metastases and the change in host immune response after low-dose total-body irradiation in tumor-bearing rats. Radiat. Res. 151, 717-724.
    • (1999) Radiat. Res. , vol.151 , pp. 717-724
    • Hashimoto, S.1    Shirato, H.2    Hosokawa, M.3    Nishioka, T.4    Kuramitsu, Y.5    Matushita, K.6    Kobayashi, M.7    Miyasaka, K.8
  • 33
    • 33846453267 scopus 로고    scopus 로고
    • Radiation therapy for painful heel spurs: results of a prospective randomized study
    • Heyd, R., Tselis, N., Ackermann, H., Röddiger, S. J., and Zamboglou, N. (2007). Radiation therapy for painful heel spurs: results of a prospective randomized study. Strahlenther. Onkol. 183, 3-9.
    • (2007) Strahlenther. Onkol. , vol.183 , pp. 3-9
    • Heyd, R.1    Tselis, N.2    Ackermann, H.3    Röddiger, S.J.4    Zamboglou, N.5
  • 34
    • 77951296033 scopus 로고    scopus 로고
    • Non-cancer diseases and non-targeted effects
    • Hildebrandt, G. (2010). Non-cancer diseases and non-targeted effects. Mutat. Res. 687, 73-77.
    • (2010) Mutat. Res. , vol.687 , pp. 73-77
    • Hildebrandt, G.1
  • 37
    • 77958111199 scopus 로고    scopus 로고
    • Dynamics of dendritic cell-T cell interactions: a role in T cell outcome
    • Hugues, S. (2010). Dynamics of dendritic cell-T cell interactions: a role in T cell outcome. Semin. Immunopathol. 32, 227-238.
    • (2010) Semin. Immunopathol. , vol.32 , pp. 227-238
    • Hugues, S.1
  • 38
    • 0028452659 scopus 로고
    • Enhancement of concanavalin A-induced proliferation of spleno-lymphocytes by low-dose-irradiated macrophages
    • Ibuki, Y., and Goto, R. (1994). Enhancement of concanavalin A-induced proliferation of spleno-lymphocytes by low-dose-irradiated macrophages. J. Radiat. Res. 35, 83-91.
    • (1994) J. Radiat. Res. , vol.35 , pp. 83-91
    • Ibuki, Y.1    Goto, R.2
  • 39
    • 1642580863 scopus 로고    scopus 로고
    • Prolongation of life span associated with immunological modification by chronic low-dose-rate irradiation in MRL-lpr/lpr mice
    • Ina, Y., and Sakai, K. (2004). Prolongation of life span associated with immunological modification by chronic low-dose-rate irradiation in MRL-lpr/lpr mice. Radiat. Res. 161, 168-173.
    • (2004) Radiat. Res. , vol.161 , pp. 168-173
    • Ina, Y.1    Sakai, K.2
  • 40
    • 32044458629 scopus 로고    scopus 로고
    • Activation of immunological network by chronic low-dose-rate irradiation in wild-type mouse strains: analysis of immune cell populations and surface molecules
    • Ina, Y., and Sakai, K. (2005). Activation of immunological network by chronic low-dose-rate irradiation in wild-type mouse strains: analysis of immune cell populations and surface molecules. Int. J. Radiat. Biol. 81, 721-729.
    • (2005) Int. J. Radiat. Biol. , vol.81 , pp. 721-729
    • Ina, Y.1    Sakai, K.2
  • 43
    • 0032773089 scopus 로고    scopus 로고
    • In vitro apoptosis in peripheral blood mononuclear cells induced by low-dose radiotherapy displays a discontinuous dose-dependence
    • Kern, P., Keilholz, L., Forster, C., Seegenschmiedt, M. H., Sauer, R., and Herrmann, M. (1999). In vitro apoptosis in peripheral blood mononuclear cells induced by low-dose radiotherapy displays a discontinuous dose-dependence. Int. J. Radiat. Biol. 75, 995-1003.
    • (1999) Int. J. Radiat. Biol. , vol.75 , pp. 995-1003
    • Kern, P.1    Keilholz, L.2    Forster, C.3    Seegenschmiedt, M.H.4    Sauer, R.5    Herrmann, M.6
  • 44
    • 0034161882 scopus 로고    scopus 로고
    • Low-dose radiotherapy selectively reduces adhesion of peripheral blood mononuclear cells to endothelium in vitro
    • Kern, P. M., Keilholz, L., Forster, C., Hallmann, R., Herrmann, M., and Seegenschmiedt, M. H. (2000). Low-dose radiotherapy selectively reduces adhesion of peripheral blood mononuclear cells to endothelium in vitro. Radiother. Oncol. 54, 273-282.
    • (2000) Radiother. Oncol. , vol.54 , pp. 273-282
    • Kern, P.M.1    Keilholz, L.2    Forster, C.3    Hallmann, R.4    Herrmann, M.5    Seegenschmiedt, M.H.6
  • 46
    • 84858019892 scopus 로고    scopus 로고
    • T-cell biology in aging, with a focus on lung disease
    • Lee, N., Shin, M. S., and Kang, I. (2012). T-cell biology in aging, with a focus on lung disease. J. Gerontol. A Biol. Sci. Med. Sci. 67, 254-263.
    • (2012) J. Gerontol. A Biol. Sci. Med. Sci. , vol.67 , pp. 254-263
    • Lee, N.1    Shin, M.S.2    Kang, I.3
  • 47
    • 0031788842 scopus 로고    scopus 로고
    • Indications and treatment schedules for irradiation of benign diseases: a survey
    • Leer, J. W. H., van Houtte, P., and Davelaara, J. (1998). Indications and treatment schedules for irradiation of benign diseases: a survey. Radiother. Oncol. 48, 249-257.
    • (1998) Radiother. Oncol. , vol.48 , pp. 249-257
    • Leer, J.W.H.1    van Houtte, P.2    Davelaara, J.3
  • 49
    • 80855144226 scopus 로고    scopus 로고
    • Macropinocytosis: an endocytic pathway for internalising large gulps
    • Lim, J. P., and Gleeson, P. A. (2011). Macropinocytosis: an endocytic pathway for internalising large gulps. Immunol. Cell Biol. 89, 836-843.
    • (2011) Immunol. Cell Biol. , vol.89 , pp. 836-843
    • Lim, J.P.1    Gleeson, P.A.2
  • 50
    • 15344346408 scopus 로고    scopus 로고
    • Nonlinear dose-response relationship in the immune system following exposure to ionizing radiation: mechanisms and implications
    • Liu, S. Z. (2003). Nonlinear dose-response relationship in the immune system following exposure to ionizing radiation: mechanisms and implications. Nonlinearity Biol. Toxicol. Med. 1, 71-92.
    • (2003) Nonlinearity Biol. Toxicol. Med. , vol.1 , pp. 71-92
    • Liu, S.Z.1
  • 51
    • 0028456120 scopus 로고
    • Changes in lymphocyte reactivity to modulatory factors following low dose ionizing radiation
    • Liu, S. Z., Han, Z. B., and Liu, W. H. (1994a). Changes in lymphocyte reactivity to modulatory factors following low dose ionizing radiation. Biomed. Environ. Sci. 7, 130-135.
    • (1994) Biomed. Environ. Sci. , vol.7 , pp. 130-135
    • Liu, S.Z.1    Han, Z.B.2    Liu, W.H.3
  • 52
    • 0028453816 scopus 로고
    • Signal transduction in lymphocytes after low dose radiation
    • Liu, S. Z., SuXu, Zhang, Y. C., and Zhao, Y. (1994b). Signal transduction in lymphocytes after low dose radiation. Chin. Med. J. (Engl.) 107, 431-436.
    • (1994) Chin. Med. J. (Engl.) , vol.107 , pp. 431-436
    • Liu, S.Z.1    SuXu Zhang, Y.C.2    Zhao, Y.3
  • 53
    • 2542486713 scopus 로고    scopus 로고
    • Role of CD28/B7 costimulation and IL-12/IL-10 interaction in the radiation-induced immune changes
    • doi: 10.1186/1471-2172-2-8
    • Liu, S. Z., Jin, S. Z., Liu, X. D., and Sun, Y. M. (2001). Role of CD28/B7 costimulation and IL-12/IL-10 interaction in the radiation-induced immune changes. BMC Immunol. 2, 1-8. doi: 10.1186/1471-2172-2-8
    • (2001) BMC Immunol. , vol.2 , pp. 1-8
    • Liu, S.Z.1    Jin, S.Z.2    Liu, X.D.3    Sun, Y.M.4
  • 54
    • 0020398149 scopus 로고
    • Physiological benefits from low levels of ionizing radiation
    • Luckey, T. D. (1982). Physiological benefits from low levels of ionizing radiation. Health Phys. 43, 771-789.
    • (1982) Health Phys. , vol.43 , pp. 771-789
    • Luckey, T.D.1
  • 55
    • 77954284275 scopus 로고    scopus 로고
    • Low-dose radiation-induced responses: focusing on epigenetic regulation
    • Ma, S., Liu, X., Jiao, B., Yang, Y., and Liu, X. (2010). Low-dose radiation-induced responses: focusing on epigenetic regulation. Int. J. Radiat. Biol. 86, 517-528.
    • (2010) Int. J. Radiat. Biol. , vol.86 , pp. 517-528
    • Ma, S.1    Liu, X.2    Jiao, B.3    Yang, Y.4    Liu, X.5
  • 57
    • 0029911692 scopus 로고    scopus 로고
    • A life stage of particle-laden rat dendritic cells in vivo: their terminal division, active phagocytosis, and translocation from the liver to the draining lymph
    • Matsuno, K., Ezaki, T., Kudo, S., and Uehara, Y. (1996). A life stage of particle-laden rat dendritic cells in vivo: their terminal division, active phagocytosis, and translocation from the liver to the draining lymph. J. Exp. Med. 183, 1865-1878.
    • (1996) J. Exp. Med. , vol.183 , pp. 1865-1878
    • Matsuno, K.1    Ezaki, T.2    Kudo, S.3    Uehara, Y.4
  • 58
    • 0035838984 scopus 로고    scopus 로고
    • Dendritic cells: specialized and regulated antigen processing machines
    • Mellman, I., and Steinman, R. M. (2001). Dendritic cells: specialized and regulated antigen processing machines. Cell 106, 255-258.
    • (2001) Cell , vol.106 , pp. 255-258
    • Mellman, I.1    Steinman, R.M.2
  • 59
    • 36849079233 scopus 로고    scopus 로고
    • Low doses of radiation reduce risk in vivo
    • Mitchel, R. E. (2006). Low doses of radiation reduce risk in vivo. Dose Response 5, 1-10.
    • (2006) Dose Response , vol.5 , pp. 1-10
    • Mitchel, R.E.1
  • 60
    • 0037336832 scopus 로고    scopus 로고
    • Low doses of radiation increase the latency of spontaneous lymphomas and spinal osteosarcomas in cancer-prone, radiation-sensitive Trp53 heterozygous mice
    • Mitchel, R. E., Jackson, J. S., Morrison, D. P., and Carlisle, S. M. (2003). Low doses of radiation increase the latency of spontaneous lymphomas and spinal osteosarcomas in cancer-prone, radiation-sensitive Trp53 heterozygous mice. Radiat. Res. 159, 320-327.
    • (2003) Radiat. Res. , vol.159 , pp. 320-327
    • Mitchel, R.E.1    Jackson, J.S.2    Morrison, D.P.3    Carlisle, S.M.4
  • 61
    • 77955602249 scopus 로고    scopus 로고
    • Key concepts in immunology
    • Moser, M., and Leo, O. (2010). Key concepts in immunology. Vaccine 28, C2-C13.
    • (2010) Vaccine , vol.28
    • Moser, M.1    Leo, O.2
  • 62
    • 77956216229 scopus 로고    scopus 로고
    • Repeated gamma irradiation attenuates collagen-induced arthritis via upregulation of regulatory T cells but not by damaging lymphocytes directly
    • Nakatsukasa, H., Tsukimoto, M., Tokunaga, A., and Kojima, S. (2010). Repeated gamma irradiation attenuates collagen-induced arthritis via upregulation of regulatory T cells but not by damaging lymphocytes directly. Radiat. Res. 174, 313-324.
    • (2010) Radiat. Res. , vol.174 , pp. 313-324
    • Nakatsukasa, H.1    Tsukimoto, M.2    Tokunaga, A.3    Kojima, S.4
  • 63
    • 17844367103 scopus 로고    scopus 로고
    • Molecular targets in radiation-induced blood-brain barrier disruption
    • Nordal, R. A., and Wong, C. S. (2005). Molecular targets in radiation-induced blood-brain barrier disruption. Int. J. Radiat. Oncol. Biol. Phys. 62, 279-287.
    • (2005) Int. J. Radiat. Oncol. Biol. Phys. , vol.62 , pp. 279-287
    • Nordal, R.A.1    Wong, C.S.2
  • 64
    • 64749085291 scopus 로고    scopus 로고
    • Current concepts and newer developments in the treatment of malignant gliomas
    • Omay, S. B., and Vogelbaum, M. A. (2009). Current concepts and newer developments in the treatment of malignant gliomas. Indian J. Cancer 46, 88-95.
    • (2009) Indian J. Cancer , vol.46 , pp. 88-95
    • Omay, S.B.1    Vogelbaum, M.A.2
  • 65
    • 21344461912 scopus 로고    scopus 로고
    • Factors effecting the Th2-like immune response after gamma-irradiation: low production of IL-12 heterodimer in antigen-presenting cells and small expression of the IL-12 receptor in T cells
    • Park, H. R., Jo, S. K., and Paik, S. G. (2005). Factors effecting the Th2-like immune response after gamma-irradiation: low production of IL-12 heterodimer in antigen-presenting cells and small expression of the IL-12 receptor in T cells. Int. J. Radiat. Biol. 81, 221-231.
    • (2005) Int. J. Radiat. Biol. , vol.81 , pp. 221-231
    • Park, H.R.1    Jo, S.K.2    Paik, S.G.3
  • 67
    • 73149113538 scopus 로고    scopus 로고
    • Perspective on the use of LNT for radiation protection and risk assessment by the U.S. Environmental Protection Agency
    • Puskin, J. S. (2009). Perspective on the use of LNT for radiation protection and risk assessment by the U.S. Environmental Protection Agency. Dose Response 7, 284-291.
    • (2009) Dose Response , vol.7 , pp. 284-291
    • Puskin, J.S.1
  • 68
    • 33947720523 scopus 로고    scopus 로고
    • Development in motion: helper T cells at work
    • Reiner, S. L. (2007). Development in motion: helper T cells at work. Cell 129, 33-36.
    • (2007) Cell , vol.129 , pp. 33-36
    • Reiner, S.L.1
  • 69
    • 27744469306 scopus 로고    scopus 로고
    • The effect of low dose gamma irradiation on the differentiation and maturation of monocyte derived dendritic cells
    • Reuben, J. M., Korbling, M., Gao, H., and Lee, B. N. (2004). The effect of low dose gamma irradiation on the differentiation and maturation of monocyte derived dendritic cells. J. Gravit. Physiol. 11, 49-52.
    • (2004) J. Gravit. Physiol. , vol.11 , pp. 49-52
    • Reuben, J.M.1    Korbling, M.2    Gao, H.3    Lee, B.N.4
  • 70
    • 78149361497 scopus 로고    scopus 로고
    • Discontinuous induction of X-linked inhibitor of apoptosis in EA.hy.926 endothelial cells is linked to NF-κB activation and mediates the anti-inflammatory properties of low-dose ionising-radiation
    • Rödel, F., Frey, B., Capalbo, G., Gaipl, U., Keilholz, L., Voll, R., Hildebrandt, G., and Rödel, C. (2010). Discontinuous induction of X-linked inhibitor of apoptosis in EA.hy.926 endothelial cells is linked to NF-κB activation and mediates the anti-inflammatory properties of low-dose ionising-radiation. Radiother. Oncol. 97, 346-351.
    • (2010) Radiother. Oncol. , vol.97 , pp. 346-351
    • Rödel, F.1    Frey, B.2    Capalbo, G.3    Gaipl, U.4    Keilholz, L.5    Voll, R.6    Hildebrandt, G.7    Rödel, C.8
  • 72
    • 38149070927 scopus 로고    scopus 로고
    • The anti-inflammatory effect of low-dose radiation therapy involves a diminished CCL20 chemokine expression and granulocyte/endothelial cell adhesion
    • Rödel, F., Hofmann, D., Auer, J., Keilholz, L., Röllinghoff, M., Sauer, R., and Beuscher, H. U. (2008). The anti-inflammatory effect of low-dose radiation therapy involves a diminished CCL20 chemokine expression and granulocyte/endothelial cell adhesion. Strahlenther. Onkol. 184, 41-47.
    • (2008) Strahlenther. Onkol. , vol.184 , pp. 41-47
    • Rödel, F.1    Hofmann, D.2    Auer, J.3    Keilholz, L.4    Röllinghoff, M.5    Sauer, R.6    Beuscher, H.U.7
  • 73
    • 0036144547 scopus 로고    scopus 로고
    • Functional and molecular aspects of anti-inflammatory effects of low-dose radiotherapy
    • Rödel, F., Kamprad, F., Sauer, R., and Hildebrandt, G. (2002). Functional and molecular aspects of anti-inflammatory effects of low-dose radiotherapy. Strahlenther. Onkol. 178, 1-9.
    • (2002) Strahlenther. Onkol. , vol.178 , pp. 1-9
    • Rödel, F.1    Kamprad, F.2    Sauer, R.3    Hildebrandt, G.4
  • 74
    • 34248550946 scopus 로고    scopus 로고
    • Radiobiological mechanisms in inflammatory diseases of low-dose radiation therapy
    • Rödel, F., Keilholz, L., Herrmann, M., Sauer, R., and Hildebrandt, G. (2007). Radiobiological mechanisms in inflammatory diseases of low-dose radiation therapy. Int. J. Radiat. Biol. 83, 357-366.
    • (2007) Int. J. Radiat. Biol. , vol.83 , pp. 357-366
    • Rödel, F.1    Keilholz, L.2    Herrmann, M.3    Sauer, R.4    Hildebrandt, G.5
  • 75
    • 0034121358 scopus 로고    scopus 로고
    • The immunobiology of low-dose total-body irradiation: more questions than answers
    • Safwat, A. (2000). The immunobiology of low-dose total-body irradiation: more questions than answers. Radiat. Res. 153, 599-604.
    • (2000) Radiat. Res. , vol.153 , pp. 599-604
    • Safwat, A.1
  • 76
    • 2442484053 scopus 로고    scopus 로고
    • Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses
    • Sakaguchi, S. (2004). Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses. Annu. Rev. Immunol. 22, 531-562.
    • (2004) Annu. Rev. Immunol. , vol.22 , pp. 531-562
    • Sakaguchi, S.1
  • 77
    • 0028348192 scopus 로고
    • Ionizing radiation and autoimmunity. Induction of autoimmune disease in mice by high dose fractionated total lymphoid irradiation and its prevention by inoculating normal T cells
    • Sakaguchi, N., Miyai, K., and Sakaguchi, S. (1994). Ionizing radiation and autoimmunity. Induction of autoimmune disease in mice by high dose fractionated total lymphoid irradiation and its prevention by inoculating normal T cells. J. Immunol. 152, 2586-2595.
    • (1994) J. Immunol. , vol.152 , pp. 2586-2595
    • Sakaguchi, N.1    Miyai, K.2    Sakaguchi, S.3
  • 78
    • 0033554726 scopus 로고    scopus 로고
    • Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
    • Sallusto, F., Lenig, D., Forster, R., Lipp, M., and Lanzavecchia, A. (1999). Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 401, 708-712.
    • (1999) Nature , vol.401 , pp. 708-712
    • Sallusto, F.1    Lenig, D.2    Forster, R.3    Lipp, M.4    Lanzavecchia, A.5
  • 79
    • 1542351347 scopus 로고    scopus 로고
    • Current developments of immunotherapy in the clinic
    • Scott, A., Mulé, J. J., and Weber, S. J. (2004). Current developments of immunotherapy in the clinic. Curr. Opin. Immunol. 16, 130-136.
    • (2004) Curr. Opin. Immunol. , vol.16 , pp. 130-136
    • Scott, A.1    Mulé, J.J.2    Weber, S.J.3
  • 80
    • 0036177177 scopus 로고    scopus 로고
    • Accommodative responses to chronic irradiation: effects of dose, dose rate, and pharmacological response modifiers
    • Seed, T. M., Inal, C., Dobson, M. E., Ghose, S., Hilyard, E., Tolle, D., and Fritz, T. E. (2002). Accommodative responses to chronic irradiation: effects of dose, dose rate, and pharmacological response modifiers. Mil. Med. 167, 82-86.
    • (2002) Mil. Med. , vol.167 , pp. 82-86
    • Seed, T.M.1    Inal, C.2    Dobson, M.E.3    Ghose, S.4    Hilyard, E.5    Tolle, D.6    Fritz, T.E.7
  • 81
    • 11144291517 scopus 로고    scopus 로고
    • Radiation therapy for nonmalignant diseases in Germany
    • German Cooperative Group on Benign Diseases (GCG-BD).
    • Seegenschmiedt, M. H., Micke, O., Willich, N., and the German Cooperative Group on Benign Diseases (GCG-BD). (2004). Radiation therapy for nonmalignant diseases in Germany. Strahlenther. Onkol. 180, 718-730.
    • (2004) Strahlenther. Onkol. , vol.180 , pp. 718-730
    • Seegenschmiedt, M.H.1    Micke, O.2    Willich, N.3
  • 82
    • 33748428203 scopus 로고    scopus 로고
    • T-cell costimulation-biology, therapeutic potential, and challenges
    • Sharpe, A. H., and Abbas, A. K. (2006). T-cell costimulation-biology, therapeutic potential, and challenges. N. Engl. J. Med. 355, 973-975.
    • (2006) N. Engl. J. Med. , vol.355 , pp. 973-975
    • Sharpe, A.H.1    Abbas, A.K.2
  • 85
    • 0031867535 scopus 로고    scopus 로고
    • Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells
    • Sparwasser, T., Koch, E. S., Vabulas, R. M., Heeg, K., Lipford, G. B., Ellwart, J. W., and Wagner, H. (1998). Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells. Eur. J. Immunol. 28, 2045-2054.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 2045-2054
    • Sparwasser, T.1    Koch, E.S.2    Vabulas, R.M.3    Heeg, K.4    Lipford, G.B.5    Ellwart, J.W.6    Wagner, H.7
  • 87
    • 23044451429 scopus 로고    scopus 로고
    • Maturation requirements for dendritic cells in T cell stimulation leading to tolerance versus immunity
    • Tan, J. K., and O'Neill, H. C. (2005). Maturation requirements for dendritic cells in T cell stimulation leading to tolerance versus immunity. J. Leukoc. Biol. 78, 319-324.
    • (2005) J. Leukoc. Biol. , vol.78 , pp. 319-324
    • Tan, J.K.1    O'Neill, H.C.2
  • 88
    • 55249119122 scopus 로고    scopus 로고
    • Repeated 0.5-Gy γ irradiation attenuates experimental autoimmune encephalomyelitis with up-regulation of regulatory T cells and suppression of IL17 production
    • Tsukimoto, M., Nakatsukasa, H., Sugawara, K., Yamashita, K., and Kojima, S. (2008). Repeated 0.5-Gy γ irradiation attenuates experimental autoimmune encephalomyelitis with up-regulation of regulatory T cells and suppression of IL17 production. Radiat. Res. 170, 429-436.
    • (2008) Radiat. Res. , vol.170 , pp. 429-436
    • Tsukimoto, M.1    Nakatsukasa, H.2    Sugawara, K.3    Yamashita, K.4    Kojima, S.5
  • 89
    • 0036360019 scopus 로고    scopus 로고
    • The enemy within: keeping self-reactive T cells at bay in the periphery
    • Walker, L. S. K., and Abbas, A. K. (2002). The enemy within: keeping self-reactive T cells at bay in the periphery. Nat. Rev. Immunol. 2, 11-19.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 11-19
    • Walker, L.S.K.1    Abbas, A.K.2
  • 90
    • 0033053344 scopus 로고    scopus 로고
    • Th2 cells as effectors in postirradiation pulmonary damage preceding fibrosis in the rat
    • Westermann, W., Schöbl, R., Rieber, E. P., and Frank, K. H. (1999). Th2 cells as effectors in postirradiation pulmonary damage preceding fibrosis in the rat. Int. J. Radiat. Biol. 75, 629-638.
    • (1999) Int. J. Radiat. Biol. , vol.75 , pp. 629-638
    • Westermann, W.1    Schöbl, R.2    Rieber, E.P.3    Frank, K.H.4
  • 91
    • 0034975464 scopus 로고    scopus 로고
    • Maturation of dendritic cells by recombinant human CD40L-trimer leads to a homogeneous cell population with enhanced surface marker expression and increased cytokine production
    • Würtzen, P. A., Nissen, M. H., and Claesson, M. H. (2001). Maturation of dendritic cells by recombinant human CD40L-trimer leads to a homogeneous cell population with enhanced surface marker expression and increased cytokine production. Scand. J. Immunol. 53, 579-587.
    • (2001) Scand. J. Immunol. , vol.53 , pp. 579-587
    • Würtzen, P.A.1    Nissen, M.H.2    Claesson, M.H.3
  • 92
    • 0037220923 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells suppress differentiation and functions of Th1 and Th2 cells, Leishmania major infection, and colitis in mice
    • Xu, D., Liu, H., Komai-Koma, M., Campbell, C., McSharry, C., Alexander, J., and Liew, F. Y. (2003). CD4+CD25+ regulatory T cells suppress differentiation and functions of Th1 and Th2 cells, Leishmania major infection, and colitis in mice. J Immunol. 170, 394-399.
    • (2003) J Immunol. , vol.170 , pp. 394-399
    • Xu, D.1    Liu, H.2    Komai-Koma, M.3    Campbell, C.4    McSharry, C.5    Alexander, J.6    Liew, F.Y.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.