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Volumn 61, Issue 12, 2012, Pages 2227-2238

Combined immunotherapy with Listeria monocytogenes-based PSA vaccine and radiation therapy leads to a therapeutic response in a murine model of prostate cancer

Author keywords

Immunotherapy; Listeria PSA vaccine; Prostate cancer; Radiation therapy

Indexed keywords

ADXS 31 142; CANCER VACCINE; CYTOKINE; GAMMA INTERFERON; LISTERIA MONOCYTOGENES PROSTATE SPECIFIC ANTIGEN VACCINE; TETRAMER; UNCLASSIFIED DRUG;

EID: 84870996402     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-012-1257-x     Document Type: Article
Times cited : (37)

References (66)
  • 2
    • 0346363495 scopus 로고    scopus 로고
    • Radical prostatectomy, external beam radiotherapy \72 Gy, external beam radiotherapy[ or = 72 Gy, permanent seed implantation, or combined seeds/external beam radiotherapy for stage T1-T2 prostate cancer
    • Kupelian PA, Potters L, Khuntia D, Ciezki JP, Reddy CA, Reuther AM, Carlson TP, Klein EA (2004) Radical prostatectomy, external beam radiotherapy \72 Gy, external beam radiotherapy[ or = 72 Gy, permanent seed implantation, or combined seeds/external beam radiotherapy for stage T1-T2 prostate cancer. Int J Radiat Oncol Biol Phys 58(1):25-33
    • (2004) Int J Radiat Oncol Biol Phys , vol.58 , Issue.1 , pp. 25-33
    • Kupelian, P.A.1    Potters, L.2    Khuntia, D.3    Ciezki, J.P.4    Reddy, C.A.5    Reuther, A.M.6    Carlson, T.P.7    Klein, E.A.8
  • 3
    • 30344481399 scopus 로고    scopus 로고
    • Long-term prognostic significance of primary Gleason pattern in patients with Gleason score 7 prostate cancer: Impact on prostate cancer specific survival
    • doi 101016/S0022-547-551 doi53470500152
    • Tollefson MK, Leibovich BC, Slezak JM, Zincke H, Blute ML (2006) Long-term prognostic significance of primary Gleason pattern in patients with Gleason score 7 prostate cancer: Impact on prostate cancer specific survival. J Urol 175(2):547-551. doi: 10.1016/S0022-5347(05)00152-7
    • (2006) J Urol , vol.175 , Issue.2 , pp. 547-551
    • Tollefson, M.K.1    Leibovich, B.C.2    Slezak, J.M.3    Zincke, H.4    Blute, M.L.5
  • 5
    • 4043153049 scopus 로고    scopus 로고
    • 6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: A randomized controlled trial
    • doi101001/jama2927821
    • D'Amico AV, Manola J, Loffredo M, Renshaw AA, DellaCroce A, Kantoff PW (2004) 6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: A randomized controlled trial. JAMA 292(7):821-827. doi:10.1001/jama.292.7.821
    • (2004) JAMA , vol.292 , Issue.7 , pp. 821-827
    • D'Amico, A.V.1    Manola, J.2    Loffredo, M.3    Renshaw, A.A.4    DellaCroce, A.5    Kantoff, P.W.6
  • 8
    • 25844459044 scopus 로고    scopus 로고
    • Combining radiotherapy and immunotherapy: A revived partnership
    • doi101016/ jijrobp2005.06032
    • Demaria S, Bhardwaj N, McBride WH, Formenti SC (2005) Combining radiotherapy and immunotherapy: A revived partnership. Int J Radiat Oncol Biol Phys 63(3):655-666. doi:10.1016/ j.ijrobp.2005.06.032
    • (2005) Int J Radiat Oncol Biol Phys , vol.63 , Issue.3 , pp. 655-666
    • Demaria, S.1    Bhardwaj, N.2    McBride, W.H.3    Formenti, S.C.4
  • 9
    • 52649153457 scopus 로고    scopus 로고
    • Synergizing radiation therapy and immunotherapy for curing incurable cancers. Opportunities and challenges
    • (discussion 1075, 1080-1061, 1084
    • Hodge JW, Guha C, Neefjes J, Gulley JL (2008) Synergizing radiation therapy and immunotherapy for curing incurable cancers. Opportunities and challenges. Oncology (Williston Park) 22 ):1064-1070 (discussion 1075, 1080-1061, 1084
    • (2008) Oncology (Williston Park , vol.22 , pp. 1064-1070
    • Hodge, J.W.1    Guha, C.2    Neefjes, J.3    Gulley, J.L.4
  • 11
    • 0034614897 scopus 로고    scopus 로고
    • Consequences of cell death: Exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells
    • Sauter B, Albert ML, Francisco L, Larsson M, Somersan S, Bhardwaj N (2000) Consequences of cell death: Exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells. J Exp Med 191(3):423-434
    • (2000) J Exp Med , vol.191 , Issue.3 , pp. 423-434
    • Sauter, B.1    Albert, M.L.2    Francisco, L.3    Larsson, M.4    Somersan, S.5    Bhardwaj, N.6
  • 12
    • 27544487075 scopus 로고    scopus 로고
    • Irradiated pancreatic cancer cells undergo both apoptosis and necrosis, and could be phagocytized by dendritic cells
    • doi101159/000087868
    • Shimamura H, Sunamura M, Tsuchihara K, Egawa S, Takeda K, Matsuno S (2005) Irradiated pancreatic cancer cells undergo both apoptosis and necrosis, and could be phagocytized by dendritic cells. Eur Surg Res 37(4):228-234. doi:10.1159/000087868
    • (2005) Eur Surg Res , vol.37 , Issue.4 , pp. 228-234
    • Shimamura, H.1    Sunamura, M.2    Tsuchihara, K.3    Egawa, S.4    Takeda, K.5    Matsuno, S.6
  • 14
    • 34548576109 scopus 로고    scopus 로고
    • Calreticulin exposure is required for the immunogenicity of gamma-irradiation and UVC light-induced apoptosis
    • doi:10.1038/sj.cdd.4402201
    • Obeid M, Panaretakis T, Joza N, Tufi R, Tesniere A, van Endert P, Zitvogel L, Kroemer G (2007) Calreticulin exposure is required for the immunogenicity of gamma-irradiation and UVC light-induced apoptosis. Cell Death Differ 14(10):1848-1850. doi:10.1038/sj.cdd.4402201
    • (2007) Cell Death Differ , vol.14 , Issue.10 , pp. 1848-1850
    • Obeid, M.1    Panaretakis, T.2    Joza, N.3    Tufi, R.4    Tesniere, A.5    Van Endert, P.6    Zitvogel, L.7    Kroemer, G.8
  • 17
    • 0037942745 scopus 로고    scopus 로고
    • Irradiation of tumor cells up-regulates Fas and enhances CTL lytic activity and CTL adoptive immunotherapy
    • Chakraborty M, Abrams SI, Camphausen K, Liu K, Scott T, Coleman CN, Hodge JW (2003) Irradiation of tumor cells up-regulates Fas and enhances CTL lytic activity and CTL adoptive immunotherapy. J Immunol 170(12):6338-6347
    • (2003) J Immunol , vol.170 , Issue.12 , pp. 6338-6347
    • Chakraborty, M.1    Abrams, S.I.2    Camphausen, K.3    Liu, K.4    Scott, T.5    Coleman, C.N.6    Hodge, J.W.7
  • 18
    • 7444258053 scopus 로고    scopus 로고
    • Sublethal irradiation of human tumor cells modulates phenotype resulting in enhanced killing by cytotoxic T lymphocytes
    • doi101158/0008-5472CAN-04-1525
    • Garnett CT, Palena C, Chakraborty M, Tsang KY, Schlom J, Hodge JW (2004) Sublethal irradiation of human tumor cells modulates phenotype resulting in enhanced killing by cytotoxic T lymphocytes. Cancer Res 64(21):7985-7994. doi:10.1158/0008-5472.CAN-04-1525
    • (2004) Cancer Res , vol.64 , Issue.21 , pp. 7985-7994
    • Garnett, C.T.1    Palena, C.2    Chakraborty, M.3    Tsang, K.Y.4    Schlom, J.5    Hodge, J.W.6
  • 19
    • 0030890586 scopus 로고    scopus 로고
    • Cellular responses to interferon-gamma
    • doi:10.1146/annurev.immunol.15.1.749
    • Boehm U, Klamp T, Groot M, Howard JC (1997) Cellular responses to interferon-gamma. Annu Rev Immunol 15:749-795. doi:10.1146/annurev.immunol.15.1. 749
    • (1997) Annu Rev Immunol , vol.15 , pp. 749-795
    • Boehm, U.1    Klamp, T.2    Groot, M.3    Howard, J.C.4
  • 20
    • 79953295544 scopus 로고    scopus 로고
    • The efficacy of radiotherapy relies upon induction of type i interferon-dependent innate and adaptive immunity
    • doi 101158/0008-5472CAN-10-2820
    • Burnette BC, Liang H, Lee Y, Chlewicki L, Khodarev NN, Weichselbaum RR, Fu YX, Auh SL (2011) The efficacy of radiotherapy relies upon induction of type i interferon-dependent innate and adaptive immunity. Cancer Res 71(7):2488-2496. doi: 10.1158/0008-5472.CAN-10-2820
    • (2011) Cancer Res , vol.71 , Issue.7 , pp. 2488-2496
    • Burnette, B.C.1    Liang, H.2    Lee, Y.3    Chlewicki, L.4    Khodarev, N.N.5    Weichselbaum, R.R.6    Fu, Y.X.7    Auh, S.L.8
  • 21
    • 20444406500 scopus 로고    scopus 로고
    • Local radiation therapy of B16 melanoma tumors increases the generation of tumor antigen-specific effector cells that traffic to the tumor
    • Lugade AA, Moran JP, Gerber SA, Rose RC, Frelinger JG, Lord EM (2005) Local radiation therapy of B16 melanoma tumors increases the generation of tumor antigen-specific effector cells that traffic to the tumor. J Immunol 174(12):7516-7523
    • (2005) J Immunol , vol.174 , Issue.12 , pp. 7516-7523
    • Lugade, A.A.1    Moran, J.P.2    Gerber, S.A.3    Rose, R.C.4    Frelinger, J.G.5    Lord, E.M.6
  • 22
    • 45449090985 scopus 로고    scopus 로고
    • Radiation-induced IFN-gamma production within the tumor microenvironment influences antitumor immunity
    • Lugade AA, Sorensen EW, Gerber SA, Moran JP, Frelinger JG, Lord EM (2008) Radiation-induced IFN-gamma production within the tumor microenvironment influences antitumor immunity. J Immunol 180(5):3132-3139
    • (2008) J Immunol , vol.180 , Issue.5 , pp. 3132-3139
    • Lugade, A.A.1    Sorensen, E.W.2    Gerber, S.A.3    Moran, J.P.4    Frelinger, J.G.5    Lord, E.M.6
  • 24
    • 0030346620 scopus 로고    scopus 로고
    • Clinical utility ofmeasurements of free and total prostate-specific antigen (PSA): A review
    • CatalonaWJ(1996) Clinical utility ofmeasurements of free and total prostate-specific antigen (PSA): A review. Prostate Suppl 7:64-69
    • (1996) Prostate Suppl , vol.7 , pp. 64-69
    • Catalona, W.J.1
  • 25
    • 0028245516 scopus 로고
    • The prostate specific antigen. Its use as a tumor marker for prostate cancer
    • Kantoff PW, Talcott JA (1994) The prostate specific antigen. Its use as a tumor marker for prostate cancer. Hematol Oncol Clin North Am 8(3):555-572
    • (1994) Hematol Oncol Clin North Am , vol.8 , Issue.3 , pp. 555-572
    • Kantoff, P.W.1    Talcott, J.A.2
  • 26
    • 0031033872 scopus 로고    scopus 로고
    • In vitro generation of human cytotoxic T lymphocytes specific for peptides derived from prostate-specific antigen
    • Correale P, Walmsley K, Nieroda C, Zaremba S, Zhu M, Schlom J, Tsang KY (1997) In vitro generation of human cytotoxic T lymphocytes specific for peptides derived from prostate-specific antigen. J Natl Cancer Inst 89(4):293-300
    • (1997) J Natl Cancer Inst , vol.89 , Issue.4 , pp. 293-300
    • Correale, P.1    Walmsley, K.2    Nieroda, C.3    Zaremba, S.4    Zhu, M.5    Schlom, J.6    Tsang, K.Y.7
  • 27
    • 0031020088 scopus 로고    scopus 로고
    • Induction of human cytotoxic T lymphocytes specific for prostate-specific antigen
    • Xue BH, Zhang Y, Sosman JA, Peace DJ (1997) Induction of human cytotoxic T lymphocytes specific for prostate-specific antigen. Prostate 30(2):73-78
    • (1997) Prostate , vol.30 , Issue.2 , pp. 73-78
    • Xue, B.H.1    Zhang, Y.2    Sosman, J.A.3    Peace, D.J.4
  • 28
    • 0035892365 scopus 로고    scopus 로고
    • Immunization with type 5 adenovirus recombinant for a tumor antigen in combination with recombinant canarypox virus (ALVAC) cytokine gene delivery induces destruction of established prostate tumors
    • Elzey BD, Siemens DR, Ratliff TL, Lubaroff DM (2001) Immunization with type 5 adenovirus recombinant for a tumor antigen in combination with recombinant canarypox virus (ALVAC) cytokine gene delivery induces destruction of established prostate tumors. Int J Cancer 94(6):842-849
    • (2001) Int J Cancer , vol.94 , Issue.6 , pp. 842-849
    • Elzey, B.D.1    Siemens, D.R.2    Ratliff, T.L.3    Lubaroff, D.M.4
  • 30
    • 8644277992 scopus 로고    scopus 로고
    • Comparison of PSA-specific CD8? CTL responses and antitumor immunity generated by plasmid DNA vaccines encoding PSA-HSP chimeric proteins
    • Pavlenko M, Roos AK, Leder C, Hansson LO, Kiessling R, Levitskaya E, Pisa P (2004) Comparison of PSA-specific CD8? CTL responses and antitumor immunity generated by plasmid DNA vaccines encoding PSA-HSP chimeric proteins. Cancer Immunol Immunother 53(12):1085-1092
    • (2004) Cancer Immunol Immunother , vol.53 , Issue.12 , pp. 1085-1092
    • Pavlenko, M.1    Roos, A.K.2    Leder, C.3    Hansson, L.O.4    Kiessling, R.5    Levitskaya, E.6    Pisa, P.7
  • 31
    • 45849139670 scopus 로고    scopus 로고
    • Development of a Listeria monocytogenes based vaccine against prostate cancer
    • doi:10.1007/s00262-008-0463-z
    • Shahabi V, Reyes-Reyes M, Wallecha A, Rivera S, Paterson Y, Maciag P (2008) Development of a Listeria monocytogenes based vaccine against prostate cancer. Cancer Immunol Immunother 57(9):1301-1313. doi:10.1007/s00262-008-0463-z
    • (2008) Cancer Immunol Immunother , vol.57 , Issue.9 , pp. 1301-1313
    • Shahabi, V.1    Reyes-Reyes, M.2    Wallecha, A.3    Rivera, S.4    Paterson, Y.5    Maciag, P.6
  • 33
    • 58149376077 scopus 로고    scopus 로고
    • Construction and characterization of an attenuated Listeria monocytogenes strain for clinical use in cancer immunotherapy
    • doi101128/CVI00274-96-103 doi101128/CVI00208
    • Wallecha A, Maciag PC, Rivera S, Paterson Y, Shahabi V (2009) Construction and characterization of an attenuated Listeria monocytogenes strain for clinical use in cancer immunotherapy. Clin Vaccine Immunol 16(1):96-103. doi:10.1128/CVI.00274-08
    • (2009) Clin Vaccine Immunol , vol.16 , Issue.1 , pp. 96-103
    • Wallecha, A.1    Maciag, P.C.2    Rivera, S.3    Paterson, Y.4    Shahabi, V.5
  • 34
    • 0026603805 scopus 로고
    • Pathogenicity and immunogenicity of Listeria monocytogenes smallplaque mutants defective for intracellular growth and cell-to-cell spread
    • Barry RA, Bouwer HG, Portnoy DA, Hinrichs DJ (1992) Pathogenicity and immunogenicity of Listeria monocytogenes smallplaque mutants defective for intracellular growth and cell-to-cell spread. Infect Immun 60(4):1625-1632
    • (1992) Infect Immun , vol.60 , Issue.4 , pp. 1625-1632
    • Barry, R.A.1    Bouwer, H.G.2    Portnoy, D.A.3    Hinrichs, D.J.4
  • 35
    • 0024741693 scopus 로고
    • Actin filaments and the growth, movement, and spread of the intracellular bacterial parasite, Listeria monocytogenes
    • Tilney LG, Portnoy DA (1989) Actin filaments and the growth, movement, and spread of the intracellular bacterial parasite, Listeria monocytogenes. J Cell Biol 109(4 Pt 1):1597-1608
    • (1989) J Cell Biol , vol.109 , Issue.4 PART 1 , pp. 1597-1608
    • Tilney, L.G.1    Portnoy, D.A.2
  • 37
    • 0027959410 scopus 로고
    • Delivery of a viral antigen to the class I processing and presentation pathway by Listeria monocytogenes
    • Ikonomidis G, Paterson Y, Kos FJ, Portnoy DA (1994) Delivery of a viral antigen to the class I processing and presentation pathway by Listeria monocytogenes. J Exp Med 180(6):2209-2218
    • (1994) J Exp Med , vol.180 , Issue.6 , pp. 2209-2218
    • Ikonomidis, G.1    Paterson, Y.2    Kos, F.J.3    Portnoy, D.A.4
  • 38
    • 0034836062 scopus 로고    scopus 로고
    • Regulation of tumor growth by IFN-gamma in cancer immunotherapy
    • doi101385/IR242201
    • Beatty GL, Paterson Y (2001) Regulation of tumor growth by IFN-gamma in cancer immunotherapy. Immunol Res 24(2):201-210. doi:10.1385/IR:24:2:201
    • (2001) Immunol Res , vol.24 , Issue.2 , pp. 201-210
    • Beatty, G.L.1    Paterson, Y.2
  • 40
    • 0035576230 scopus 로고    scopus 로고
    • Two Listeria monocytogenes vaccine vectors that express different molecular forms of human papilloma virus-16 (HPV-16) E7 induce qualitatively different T cell immunity that correlates with their ability to induce regression of established tumors immortalized by HPV-16
    • Gunn GR, Zubair A, Peters C, Pan ZK, Wu TC, Paterson Y (2001) Two Listeria monocytogenes vaccine vectors that express different molecular forms of human papilloma virus-16 (HPV-16) E7 induce qualitatively different T cell immunity that correlates with their ability to induce regression of established tumors immortalized by HPV-16. J Immunol 167(11):6471-6479
    • (2001) J Immunol , vol.167 , Issue.11 , pp. 6471-6479
    • Gunn, G.R.1    Zubair, A.2    Peters, C.3    Pan, Z.K.4    Wu, T.C.5    Paterson, Y.6
  • 41
    • 4344608083 scopus 로고    scopus 로고
    • CD4? CD25? regulatory T cells that secrete TGFbeta and IL-10 are preferentially induced by a vaccine vector
    • Hussain SF, Paterson Y (2004) CD4? CD25? regulatory T cells that secrete TGFbeta and IL-10 are preferentially induced by a vaccine vector. J Immunother 27(5):339-346
    • (2004) J Immunother , vol.27 , Issue.5 , pp. 339-346
    • Hussain, S.F.1    Paterson, Y.2
  • 42
    • 54249117270 scopus 로고    scopus 로고
    • Cancer immunotherapy targeting the high molecular weight melanoma-associated antigen protein results in a broad antitumor response and reduction of pericytes in the tumor vasculature
    • doi101158/0008-5472CAN-08-0287
    • Maciag PC, Seavey MM, Pan ZK, Ferrone S, Paterson Y (2008) Cancer immunotherapy targeting the high molecular weight melanoma-associated antigen protein results in a broad antitumor response and reduction of pericytes in the tumor vasculature. Cancer Res 68(19):8066-8075. doi:10.1158/0008-5472.CAN-08- 0287
    • (2008) Cancer Res , vol.68 , Issue.19 , pp. 8066-8075
    • Maciag, P.C.1    Seavey, M.M.2    Pan, Z.K.3    Ferrone, S.4    Paterson, Y.5
  • 43
    • 24744433094 scopus 로고    scopus 로고
    • Fusion to Listeriolysin O and delivery by Listeria monocytogenes enhances the immunogenicity of HER-2/neu and reveals subdominant epitopes in the FVB/N mouse
    • Singh R, Dominiecki ME, Jaffee EM, Paterson Y (2005) Fusion to Listeriolysin O and delivery by Listeria monocytogenes enhances the immunogenicity of HER-2/neu and reveals subdominant epitopes in the FVB/N mouse. J Immunol 175(6): 3663-3673
    • (2005) J Immunol , vol.175 , Issue.6 , pp. 3663-3673
    • Singh, R.1    Dominiecki, M.E.2    Jaffee, E.M.3    Paterson, Y.4
  • 44
    • 33947244053 scopus 로고    scopus 로고
    • In the FVB/N HER-2/neu transgenic mouse both peripheral and central tolerance limit the immune response targeting HER-2/neu induced by Listeria monocytogenes-based vaccines
    • doi101007/s00262-006-0237-0244
    • Singh R, Paterson Y (2007) In the FVB/N HER-2/neu transgenic mouse both peripheral and central tolerance limit the immune response targeting HER-2/neu induced by Listeria monocytogenes-based vaccines. Cancer Immunol Immunother 56(6):927-938. doi:10.1007/s00262-006-0237-4
    • (2007) Cancer Immunol Immunother , vol.56 , Issue.6 , pp. 927-938
    • Singh, R.1    Paterson, Y.2
  • 45
    • 33750560447 scopus 로고    scopus 로고
    • Flt3L therapy following localized tumor irradiation generates long-term protective immune response in metastatic lung cancer: Its implication in designing a vaccination strategy
    • doi 101159/000096288
    • Chakravarty PK, Guha C, Alfieri A, Beri V, Niazova Z, Deb NJ, Fan Z, Thomas EK, Vikram B (2006) Flt3L therapy following localized tumor irradiation generates long-term protective immune response in metastatic lung cancer: Its implication in designing a vaccination strategy. Oncology 70(4):245-254. doi: 10.1159/000096288
    • (2006) Oncology , vol.70 , Issue.4 , pp. 245-254
    • Chakravarty, P.K.1    Guha, C.2    Alfieri, A.3    Beri, V.4    Niazova, Z.5    Deb, N.J.6    Fan, Z.7    Thomas, E.K.8    Vikram, B.9
  • 48
    • 3042569675 scopus 로고    scopus 로고
    • External beam radiation of tumors alters phenotype of tumor cells to render them susceptible to vaccinemediated T-cell killing
    • doi 101158/0008-5472CAN-04-0073
    • Chakraborty M, Abrams SI, Coleman CN, Camphausen K, Schlom J, Hodge JW (2004) External beam radiation of tumors alters phenotype of tumor cells to render them susceptible to vaccinemediated T-cell killing. Cancer Res 64(12):4328-4337. doi: 10.1158/0008-5472.CAN-04-0073
    • (2004) Cancer Res , vol.64 , pp. 124328-4337
    • Chakraborty, M.1    Abrams, S.I.2    Coleman, C.N.3    Camphausen, K.4    Schlom, J.5    Hodge, J.W.6
  • 50
    • 19544385574 scopus 로고    scopus 로고
    • Identification of an immunodominant H-2D(b)-restricted CTL epitope of human PSA
    • doi101002/ros 20221
    • Pavlenko M, Leder C, Roos AK, Levitsky V, Pisa P (2005) Identification of an immunodominant H-2D(b)-restricted CTL epitope of human PSA. Prostate 64(1):50-59. doi:10.1002/pros. 20221
    • (2005) Prostate , vol.64 , Issue.1 , pp. 50-59
    • Pavlenko, M.1    Leder, C.2    Roos, A.K.3    Levitsky, V.4    Pisa, P.5
  • 52
    • 34248594934 scopus 로고    scopus 로고
    • Is the alpha/beta value for prostate tumours low enough to be safely used in clinical trials?
    • doi101016/jclon2007.02.007
    • Dasu A (2007) Is the alpha/beta value for prostate tumours low enough to be safely used in clinical trials? Clin Oncol (R Coll Radiol) 19(5):289-301. doi:10.1016/j.clon.2007.02.007
    • (2007) Clin Oncol (R Coll Radiol , vol.19 , Issue.5 , pp. 289-301
    • Dasu, A.1
  • 53
    • 0035450897 scopus 로고    scopus 로고
    • A simple analytic derivation suggests that prostate cancer alpha/beta ratio is low
    • King CR, Fowler JF (2001) A simple analytic derivation suggests that prostate cancer alpha/beta ratio is low. Int J Radiat Oncol Biol Phys 51(1):213-214
    • (2001) Int J Radiat Oncol Biol Phys , vol.51 , Issue.1 , pp. 213-214
    • King, C.R.1    Fowler, J.F.2
  • 56
    • 68549135290 scopus 로고    scopus 로고
    • Integrated data from 2 randomized, double-blind, placebo-controlled, phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer
    • doi:10.1002/cncr. 24429
    • Higano CS, Schellhammer PF, Small EJ, Burch PA, Nemunaitis J, Yuh L, Provost N, Frohlich MW (2009) Integrated data from 2 randomized, double-blind, placebo-controlled, phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer. Cancer 115(16):3670-3679. doi:10.1002/cncr. 24429
    • (2009) Cancer , vol.115 , Issue.16 , pp. 3670-3679
    • Higano, C.S.1    Schellhammer, P.F.2    Small, E.J.3    Burch, P.A.4    Nemunaitis, J.5    Yuh, L.6    Provost, N.7    Frohlich, M.W.8
  • 57
    • 38649120894 scopus 로고    scopus 로고
    • Listeriolysin O is an improved protein carrier for lymphoma immunoglobulin idiotype and provides systemic protection against 38C13 lymphoma
    • doi101007/ s00262-493-505 doi101007/ s00007
    • Neeson P, Pan ZK, Paterson Y (2008) Listeriolysin O is an improved protein carrier for lymphoma immunoglobulin idiotype and provides systemic protection against 38C13 lymphoma. Cancer Immunol Immunother 57(4):493-505. doi:10.1007/ s00262-007-0388-y
    • (2008) Cancer Immunol Immunother , vol.57 , Issue.4 , pp. 493-505
    • Neeson, P.1    Pan, Z.K.2    Paterson, Y.3
  • 58
    • 0036787490 scopus 로고    scopus 로고
    • Phase I study of a vaccine using recombinant vaccinia virus expressing PSA (rV-PSA) in patients with metastatic androgen-independent prostate cancer
    • doi101002/ros10130
    • Gulley J, Chen AP, Dahut W, Arlen PM, Bastian A, Steinberg SM, Tsang K, Panicali D, Poole D, Schlom J, Michael Hamilton J (2002) Phase I study of a vaccine using recombinant vaccinia virus expressing PSA (rV-PSA) in patients with metastatic androgen-independent prostate cancer. Prostate 53(2):109-117. doi:10.1002/pros.10130
    • (2002) Prostate , vol.53 , Issue.2 , pp. 109-117
    • Gulley, J.1    Chen, A.P.2    Dahut, W.3    Arlen, P.M.4    Bastian, A.5    Steinberg, S.M.6    Tsang, K.7    Panicali, D.8    Poole, D.9    Schlom, J.10    Michael Hamilton, J.11
  • 59
    • 0036167308 scopus 로고    scopus 로고
    • Autologous dendritic cells transfected with prostate-specific antigen RNA stimulate CTL responses against metastatic prostate tumors
    • doi101172/JCI14364
    • Heiser A, Coleman D, Dannull J, Yancey D, Maurice MA, Lallas CD, Dahm P, Niedzwiecki D, Gilboa E, Vieweg J (2002) Autologous dendritic cells transfected with prostate-specific antigen RNA stimulate CTL responses against metastatic prostate tumors. J Clin Invest 109(3):409-417. doi:10.1172/JCI14364
    • (2002) J Clin Invest , vol.109 , Issue.3 , pp. 409-417
    • Heiser, A.1    Coleman, D.2    Dannull, J.3    Yancey, D.4    Maurice, M.A.5    Lallas, C.D.6    Dahm, P.7    Niedzwiecki, D.8    Gilboa, E.9    Vieweg, J.10
  • 60
    • 77951833365 scopus 로고    scopus 로고
    • Prostate-specific antigen (PSA) is activated by KLK2 in prostate cancer ex vivo models and in prostate-targeted PSA/ KLK2 double transgenic mice
    • doi: 10.1002/pros.21111
    • Williams SA, Xu Y, De Marzo AM, Isaacs JT, Denmeade SR (2010) Prostate-specific antigen (PSA) is activated by KLK2 in prostate cancer ex vivo models and in prostate-targeted PSA/ KLK2 double transgenic mice. Prostate 70(7):788-796. doi: 10.1002/pros.21111
    • (2010) Prostate , vol.70 , Issue.7 , pp. 788-796
    • Williams, S.A.1    Xu, Y.2    De Marzo, A.M.3    Isaacs, J.T.4    Denmeade, S.R.5
  • 62
    • 1542267898 scopus 로고    scopus 로고
    • High dose rate brachytherapy asprostate cancer monotherapy reduces toxicity compared to low dose rate palladium seeds
    • doi 101097/01ju00001132993440422
    • Grills IS, Martinez AA, Hollander M, Huang R, Goldman K, Chen PY, Gustafson GS (2004) High dose rate brachytherapy asprostate cancer monotherapy reduces toxicity compared to low dose rate palladium seeds. J Urol 171(3):1098-1104. doi: 10.1097/01.ju.0000113299.34404.22
    • (2004) J Urol , vol.171 , Issue.3 , pp. 1098-1104
    • Grills, I.S.1    Martinez, A.A.2    Hollander, M.3    Huang, R.4    Goldman, K.5    Chen, P.Y.6    Gustafson, G.S.7
  • 64
    • 46449111825 scopus 로고    scopus 로고
    • Risk of prostate cancer recurrence in men treated with radiation alone or in conjunction with combined or less than combined androgen suppression therapy
    • doi101200/JCO2007.159699
    • D'Amico AV, Chen MH, Renshaw AA, Loffredo B, Kantoff PW (2008) Risk of prostate cancer recurrence in men treated with radiation alone or in conjunction with combined or less than combined androgen suppression therapy. J Clin Oncol 26(18):2979-2983. doi:10.1200/JCO.2007.15.9699
    • (2008) J Clin Oncol , vol.26 , Issue.18 , pp. 2979-2983
    • D'Amico, A.V.1    Chen, M.H.2    Renshaw, A.A.3    Loffredo, B.4    Kantoff, P.W.5
  • 65
    • 67349153373 scopus 로고    scopus 로고
    • The first clinical use of a live-attenuated Listeria monocytogenes vaccine: A phase I safety study of Lm-LLO-E7 in patients with advanced carcinoma of the cervix
    • doi101016/jvaccine 2009.04041
    • Maciag PC, Radulovic S, Rothman J (2009) The first clinical use of a live-attenuated Listeria monocytogenes vaccine: A phase I safety study of Lm-LLO-E7 in patients with advanced carcinoma of the cervix. Vaccine 27(30):3975-3983. doi:10.1016/j.vaccine. 2009.04.041
    • (2009) Vaccine , vol.27 , Issue.30 , pp. 3975-3983
    • Maciag, P.C.1    Radulovic, S.2    Rothman, J.3


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