메뉴 건너뛰기




Volumn 7, Issue 5, 2012, Pages

An in situ autologous tumor vaccination with combined radiation therapy and TLR9 agonist therapy

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN G ANTIBODY; INTERLEUKIN 10; TOLL LIKE RECEPTOR 9; TOLL LIKE RECEPTOR AGONIST; ANTINEOPLASTIC AGENT; CANCER ANTIBODY; TUMOR ANTIGEN;

EID: 84861630513     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0038111     Document Type: Article
Times cited : (52)

References (39)
  • 1
    • 0029639928 scopus 로고
    • Recent advances in radiation oncology
    • Lichter AS, Lawrence TS, (1995) Recent advances in radiation oncology. N Engl J Med 332: 371-379.
    • (1995) N Engl J Med , vol.332 , pp. 371-379
    • Lichter, A.S.1    Lawrence, T.S.2
  • 2
    • 29244443382 scopus 로고    scopus 로고
    • Radiation-enhanced immune response to cancer: workshop, Anaheim, CA, April 17, 2005
    • Sutherland RM, (2006) Radiation-enhanced immune response to cancer: workshop, Anaheim, CA, April 17, 2005. Int J Radiat Oncol Biol Phys 64: 3-5.
    • (2006) Int J Radiat Oncol Biol Phys , vol.64 , pp. 3-5
    • Sutherland, R.M.1
  • 3
    • 0035988623 scopus 로고    scopus 로고
    • Immune modulation by ionizing radiation and its implications for cancer immunotherapy
    • Friedman EJ, (2002) Immune modulation by ionizing radiation and its implications for cancer immunotherapy. Curr Pharm Des 8: 1765-1780.
    • (2002) Curr Pharm Des , vol.8 , pp. 1765-1780
    • Friedman, E.J.1
  • 5
    • 78049428921 scopus 로고    scopus 로고
    • Harnessing innate immunity to suppress lymphoma
    • Stevenson FK, Johnson PW, (2010) Harnessing innate immunity to suppress lymphoma. J Clin Oncol 28: 4295-4296.
    • (2010) J Clin Oncol , vol.28 , pp. 4295-4296
    • Stevenson, F.K.1    Johnson, P.W.2
  • 6
    • 33646704729 scopus 로고    scopus 로고
    • Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy
    • Reits EA, Hodge JW, Herberts CA, Groothuis TA, Chakraborty M, et al. (2006) Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy. J Exp Med 203: 1259-1271.
    • (2006) J Exp Med , vol.203 , pp. 1259-1271
    • Reits, E.A.1    Hodge, J.W.2    Herberts, C.A.3    Groothuis, T.A.4    Chakraborty, M.5
  • 7
    • 33747616867 scopus 로고    scopus 로고
    • Gamma-radiation upregulates MHC class I/II and ICAM-I molecules in multiple myeloma cell lines and primary tumors
    • Chiriva-Internati M, Grizzi F, Pinkston J, Morrow KJ, D'Cunha N, et al. (2006) Gamma-radiation upregulates MHC class I/II and ICAM-I molecules in multiple myeloma cell lines and primary tumors. In Vitro Cell Dev Biol Anim 42: 89-95.
    • (2006) In Vitro Cell Dev Biol Anim , vol.42 , pp. 89-95
    • Chiriva-Internati, M.1    Grizzi, F.2    Pinkston, J.3    Morrow, K.J.4    D'Cunha, N.5
  • 8
    • 51549088023 scopus 로고    scopus 로고
    • Radiation-induced CXCL16 release by breast cancer cells attracts effector T cells
    • Matsumura S, Wang B, Kawashima N, Braunstein S, Badura M, et al. (2008) Radiation-induced CXCL16 release by breast cancer cells attracts effector T cells. J Immunol 181: 3099-3107.
    • (2008) J Immunol , vol.181 , pp. 3099-3107
    • Matsumura, S.1    Wang, B.2    Kawashima, N.3    Braunstein, S.4    Badura, M.5
  • 9
    • 45449090985 scopus 로고    scopus 로고
    • Radiation-induced IFN-gamma production within the tumor microenvironment influences antitumor immunity
    • Lugade AA, Sorensen EW, Gerber SA, Moran JP, Frelinger JG, et al. (2008) Radiation-induced IFN-gamma production within the tumor microenvironment influences antitumor immunity. J Immunol 180: 3132-3139.
    • (2008) J Immunol , vol.180 , pp. 3132-3139
    • Lugade, A.A.1    Sorensen, E.W.2    Gerber, S.A.3    Moran, J.P.4    Frelinger, J.G.5
  • 10
    • 3042569675 scopus 로고    scopus 로고
    • External beam radiation of tumors alters phenotype of tumor cells to render them susceptible to vaccine-mediated T-cell killing
    • Chakraborty M, Abrams SI, Coleman CN, Camphausen K, Schlom J, et al. (2004) External beam radiation of tumors alters phenotype of tumor cells to render them susceptible to vaccine-mediated T-cell killing. Cancer Res 64: 4328-4337.
    • (2004) Cancer Res , vol.64 , pp. 4328-4337
    • Chakraborty, M.1    Abrams, S.I.2    Coleman, C.N.3    Camphausen, K.4    Schlom, J.5
  • 12
    • 37849002321 scopus 로고    scopus 로고
    • Toll-like receptor 9 (TLR9) agonists in the treatment of cancer
    • Krieg AM, (2008) Toll-like receptor 9 (TLR9) agonists in the treatment of cancer. Oncogene 27: 161-167.
    • (2008) Oncogene , vol.27 , pp. 161-167
    • Krieg, A.M.1
  • 13
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira S, Uematsu S, Takeuchi O, (2006) Pathogen recognition and innate immunity. Cell 124: 783-801.
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 14
    • 34250698370 scopus 로고    scopus 로고
    • Ligand-induced conformational changes allosterically activate Toll-like receptor 9
    • Latz E, Verma A, Visintin A, Gong M, Sirois CM, et al. (2007) Ligand-induced conformational changes allosterically activate Toll-like receptor 9. Nat Immunol 8: 772-779.
    • (2007) Nat Immunol , vol.8 , pp. 772-779
    • Latz, E.1    Verma, A.2    Visintin, A.3    Gong, M.4    Sirois, C.M.5
  • 15
    • 5444262511 scopus 로고    scopus 로고
    • Toll-like receptor control of the adaptive immune responses
    • Iwasaki A, Medzhitov R, (2004) Toll-like receptor control of the adaptive immune responses. Nat Immunol 5: 987-995.
    • (2004) Nat Immunol , vol.5 , pp. 987-995
    • Iwasaki, A.1    Medzhitov, R.2
  • 16
    • 84872747134 scopus 로고    scopus 로고
    • Interleukin-18 and the toll-like receptor 9 ligand CpG stimulate murine splenic natural killer dendritic cells (NKDC) to proliferate and secrete IFN-gamma
    • Chaudhry U, Kingham P, Plitas G, Katz S, Stabelford J, et al. (2006) Interleukin-18 and the toll-like receptor 9 ligand CpG stimulate murine splenic natural killer dendritic cells (NKDC) to proliferate and secrete IFN-gamma. Journal of the American College of Surgeons 203: S79-S80.
    • (2006) Journal of the American College of Surgeons , vol.203
    • Chaudhry, U.1    Kingham, P.2    Plitas, G.3    Katz, S.4    Stabelford, J.5
  • 17
    • 33751266583 scopus 로고    scopus 로고
    • Combined Stimulation with Interleukin-18 and CpG Induces Murine Natural Killer Dendritic Cells to Produce IFN-{gamma} and Inhibit Tumor Growth
    • Chaudhry UI, Kingham TP, Plitas G, Katz SC, Raab JR, et al. (2006) Combined Stimulation with Interleukin-18 and CpG Induces Murine Natural Killer Dendritic Cells to Produce IFN-{gamma} and Inhibit Tumor Growth. Cancer Res 66: 10497-10504.
    • (2006) Cancer Res , vol.66 , pp. 10497-10504
    • Chaudhry, U.I.1    Kingham, T.P.2    Plitas, G.3    Katz, S.C.4    Raab, J.R.5
  • 18
    • 33745946911 scopus 로고    scopus 로고
    • Therapeutic potential of Toll-like receptor 9 activation
    • Krieg AM, (2006) Therapeutic potential of Toll-like receptor 9 activation. Nat Rev Drug Discov 5: 471-484.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 471-484
    • Krieg, A.M.1
  • 19
    • 63449142715 scopus 로고    scopus 로고
    • Treatment of mammary carcinomas in HER-2 transgenic mice through combination of genetic vaccine and an agonist of Toll-like receptor 9
    • Aurisicchio L, Peruzzi D, Conforti A, Dharmapuri S, Biondo A, et al. (2009) Treatment of mammary carcinomas in HER-2 transgenic mice through combination of genetic vaccine and an agonist of Toll-like receptor 9. Clin Cancer Res 15: 1575-1584.
    • (2009) Clin Cancer Res , vol.15 , pp. 1575-1584
    • Aurisicchio, L.1    Peruzzi, D.2    Conforti, A.3    Dharmapuri, S.4    Biondo, A.5
  • 20
    • 55249107642 scopus 로고    scopus 로고
    • Toll-like receptors: lessons to learn from normal and malignant human B cells
    • Chiron D, Bekeredjian-Ding I, Pellat-Deceunynck C, Bataille R, Jego G, (2008) Toll-like receptors: lessons to learn from normal and malignant human B cells. Blood 112: 2205-2213.
    • (2008) Blood , vol.112 , pp. 2205-2213
    • Chiron, D.1    Bekeredjian-Ding, I.2    Pellat-Deceunynck, C.3    Bataille, R.4    Jego, G.5
  • 21
    • 34547619033 scopus 로고    scopus 로고
    • TLR9 agonist acts by different mechanisms synergizing with bevacizumab in sensitive and cetuximab-resistant colon cancer xenografts
    • Damiano V, Caputo R, Garofalo S, Bianco R, Rosa R, et al. (2007) TLR9 agonist acts by different mechanisms synergizing with bevacizumab in sensitive and cetuximab-resistant colon cancer xenografts. Proc Natl Acad Sci U S A 104: 12468-12473.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 12468-12473
    • Damiano, V.1    Caputo, R.2    Garofalo, S.3    Bianco, R.4    Rosa, R.5
  • 22
    • 0034142182 scopus 로고    scopus 로고
    • Delineation of a CpG phosphorothioate oligodeoxynucleotide for activating primate immune responses in vitro and in vivo
    • Hartmann G, Weeratna RD, Ballas ZK, Payette P, Blackwell S, et al. (2000) Delineation of a CpG phosphorothioate oligodeoxynucleotide for activating primate immune responses in vitro and in vivo. J Immunol 164: 1617-1624.
    • (2000) J Immunol , vol.164 , pp. 1617-1624
    • Hartmann, G.1    Weeratna, R.D.2    Ballas, Z.K.3    Payette, P.4    Blackwell, S.5
  • 24
    • 0037809185 scopus 로고    scopus 로고
    • Divergent synthetic nucleotide motif recognition pattern: design and development of potent immunomodulatory oligodeoxyribonucleotide agents with distinct cytokine induction profiles
    • Kandimalla ER, Bhagat L, Wang D, Yu D, Zhu FG, et al. (2003) Divergent synthetic nucleotide motif recognition pattern: design and development of potent immunomodulatory oligodeoxyribonucleotide agents with distinct cytokine induction profiles. Nucleic Acids Res 31: 2393-2400.
    • (2003) Nucleic Acids Res , vol.31 , pp. 2393-2400
    • Kandimalla, E.R.1    Bhagat, L.2    Wang, D.3    Yu, D.4    Zhu, F.G.5
  • 25
    • 15044356671 scopus 로고    scopus 로고
    • Oral administration of second-generation immunomodulatory oligonucleotides induces mucosal Th1 immune responses and adjuvant activity
    • Wang D, Kandimalla ER, Yu D, Tang JX, Agrawal S, (2005) Oral administration of second-generation immunomodulatory oligonucleotides induces mucosal Th1 immune responses and adjuvant activity. Vaccine 23: 2614-2622.
    • (2005) Vaccine , vol.23 , pp. 2614-2622
    • Wang, D.1    Kandimalla, E.R.2    Yu, D.3    Tang, J.X.4    Agrawal, S.5
  • 26
    • 33746092105 scopus 로고    scopus 로고
    • Chemotherapy and chemosensitization of non-small cell lung cancer with a novel immunomodulatory oligonucleotide targeting Toll-like receptor 9
    • Wang H, Rayburn ER, Wang W, Kandimalla ER, Agrawal S, et al. (2006) Chemotherapy and chemosensitization of non-small cell lung cancer with a novel immunomodulatory oligonucleotide targeting Toll-like receptor 9. Molecular Cancer Therapeutics 5: 1585-1592.
    • (2006) Molecular Cancer Therapeutics , vol.5 , pp. 1585-1592
    • Wang, H.1    Rayburn, E.R.2    Wang, W.3    Kandimalla, E.R.4    Agrawal, S.5
  • 27
    • 1842841708 scopus 로고    scopus 로고
    • Immunopharmacological and antitumor effects of second-generation immunomodulatory oligonucleotides containing synthetic CpR motifs
    • Wang D, Li Y, Yu D, Song SS, Kandimalla ER, et al. (2004) Immunopharmacological and antitumor effects of second-generation immunomodulatory oligonucleotides containing synthetic CpR motifs. Int J Oncol 24: 901-908.
    • (2004) Int J Oncol , vol.24 , pp. 901-908
    • Wang, D.1    Li, Y.2    Yu, D.3    Song, S.S.4    Kandimalla, E.R.5
  • 28
    • 77956488040 scopus 로고    scopus 로고
    • Tumor vaccine composed of C-class CpG oligodeoxynucleotides and irradiated tumor cells induces long-term antitumor immunity
    • Cerkovnik P, Novakovic BJ, Stegel V, Novakovic S, (2010) Tumor vaccine composed of C-class CpG oligodeoxynucleotides and irradiated tumor cells induces long-term antitumor immunity. BMC Immunol 11: 45.
    • (2010) BMC Immunol , vol.11 , pp. 45
    • Cerkovnik, P.1    Novakovic, B.J.2    Stegel, V.3    Novakovic, S.4
  • 29
    • 65349097349 scopus 로고    scopus 로고
    • Combination immunotherapy with radiation and CpG-based tumor vaccination for the eradication of radio- and immuno-resistant lung carcinoma cells
    • Chamoto K, Takeshima T, Wakita D, Ohkuri T, Ashino S, et al. (2009) Combination immunotherapy with radiation and CpG-based tumor vaccination for the eradication of radio- and immuno-resistant lung carcinoma cells. Cancer Sci 100: 934-939.
    • (2009) Cancer Sci , vol.100 , pp. 934-939
    • Chamoto, K.1    Takeshima, T.2    Wakita, D.3    Ohkuri, T.4    Ashino, S.5
  • 30
    • 11344265206 scopus 로고    scopus 로고
    • Targeting toll-like receptor 9 with CpG oligodeoxynucleotides enhances tumor response to fractionated radiotherapy
    • Mason KA, Ariga H, Neal R, Valdecanas D, Hunter N, et al. (2005) Targeting toll-like receptor 9 with CpG oligodeoxynucleotides enhances tumor response to fractionated radiotherapy. Clin Cancer Res 11: 361-369.
    • (2005) Clin Cancer Res , vol.11 , pp. 361-369
    • Mason, K.A.1    Ariga, H.2    Neal, R.3    Valdecanas, D.4    Hunter, N.5
  • 31
    • 3442879246 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotide enhances tumor response to radiation
    • Milas L, Mason KA, Ariga H, Hunter N, Neal R, et al. (2004) CpG oligodeoxynucleotide enhances tumor response to radiation. Cancer Res 64: 5074-5077.
    • (2004) Cancer Res , vol.64 , pp. 5074-5077
    • Milas, L.1    Mason, K.A.2    Ariga, H.3    Hunter, N.4    Neal, R.5
  • 32
    • 0037109211 scopus 로고    scopus 로고
    • Immunomers'-novel 3'-3'-linked CpG oligodeoxyribonucleotides as potent immunomodulatory agents
    • Yu D, Kandimalla ER, Bhagat L, Tang JY, Cong Y, et al. (2002) 'Immunomers'-novel 3'-3'-linked CpG oligodeoxyribonucleotides as potent immunomodulatory agents. Nucleic Acids Res 30: 4460-4469.
    • (2002) Nucleic Acids Res , vol.30 , pp. 4460-4469
    • Yu, D.1    Kandimalla, E.R.2    Bhagat, L.3    Tang, J.Y.4    Cong, Y.5
  • 33
    • 0033595632 scopus 로고    scopus 로고
    • Humoral immune responses of cancer patients against "Cancer-Testis" antigen NY-ESO-1: correlation with clinical events
    • Jager E, Stockert E, Zidianakis Z, Chen YT, Karbach J, et al. (1999) Humoral immune responses of cancer patients against "Cancer-Testis" antigen NY-ESO-1: correlation with clinical events. Int J Cancer 84: 506-510.
    • (1999) Int J Cancer , vol.84 , pp. 506-510
    • Jager, E.1    Stockert, E.2    Zidianakis, Z.3    Chen, Y.T.4    Karbach, J.5
  • 34
    • 10744227784 scopus 로고    scopus 로고
    • A dinucleotide motif in oligonucleotides shows potent immunomodulatory activity and overrides species-specific recognition observed with CpG motif
    • Kandimalla ER, Bhagat L, Zhu FG, Yu D, Cong YP, et al. (2003) A dinucleotide motif in oligonucleotides shows potent immunomodulatory activity and overrides species-specific recognition observed with CpG motif. Proc Natl Acad Sci U S A 100: 14303-14308.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 14303-14308
    • Kandimalla, E.R.1    Bhagat, L.2    Zhu, F.G.3    Yu, D.4    Cong, Y.P.5
  • 35
    • 14044269485 scopus 로고    scopus 로고
    • Natural killer dendritic cells have both antigen presenting and lytic function and in response to CpG produce IFN-gamma via autocrine IL-12
    • Pillarisetty VG, Katz SC, Bleier JI, Shah AB, Dematteo RP, (2005) Natural killer dendritic cells have both antigen presenting and lytic function and in response to CpG produce IFN-gamma via autocrine IL-12. J Immunol 174: 2612-2618.
    • (2005) J Immunol , vol.174 , pp. 2612-2618
    • Pillarisetty, V.G.1    Katz, S.C.2    Bleier, J.I.3    Shah, A.B.4    Dematteo, R.P.5
  • 36
    • 69949085196 scopus 로고    scopus 로고
    • Fractionated but not single-dose radiotherapy induces an immune-mediated abscopal effect when combined with anti-CTLA-4 antibody
    • Dewan MZ, Galloway AE, Kawashima N, Dewyngaert JK, Babb JS, et al. (2009) Fractionated but not single-dose radiotherapy induces an immune-mediated abscopal effect when combined with anti-CTLA-4 antibody. Clin Cancer Res 15: 5379-5388.
    • (2009) Clin Cancer Res , vol.15 , pp. 5379-5388
    • Dewan, M.Z.1    Galloway, A.E.2    Kawashima, N.3    Dewyngaert, J.K.4    Babb, J.S.5
  • 37
    • 33846057130 scopus 로고    scopus 로고
    • Calreticulin exposure dictates the immunogenicity of cancer cell death
    • Obeid M, Tesniere A, Ghiringhelli F, Fimia GM, Apetoh L, et al. (2007) Calreticulin exposure dictates the immunogenicity of cancer cell death. Nat Med 13: 54-61.
    • (2007) Nat Med , vol.13 , pp. 54-61
    • Obeid, M.1    Tesniere, A.2    Ghiringhelli, F.3    Fimia, G.M.4    Apetoh, L.5
  • 38
    • 52649153457 scopus 로고    scopus 로고
    • Synergizing radiation therapy and immunotherapy for curing incurable cancers. Opportunities and challenges
    • discussion 1075, 1080-1061, 1084
    • Hodge JW, Guha C, Neefjes J, Gulley JL, (2008) Synergizing radiation therapy and immunotherapy for curing incurable cancers. Opportunities and challenges. Oncology (Williston Park) 22: 1064-1070; discussion 1075, 1080-1061, 1084.
    • (2008) Oncology (Williston Park) , vol.22 , pp. 1064-1070
    • Hodge, J.W.1    Guha, C.2    Neefjes, J.3    Gulley, J.L.4
  • 39
    • 84855405251 scopus 로고    scopus 로고
    • TLR9 agonist protects mice from radiation-induced gastrointestinal syndrome
    • Saha S, Bhanja P, Liu L, Alfieri AA, Yu D, et al. (2012) TLR9 agonist protects mice from radiation-induced gastrointestinal syndrome. PLoS One 7: e29357.
    • (2012) PLoS One , vol.7
    • Saha, S.1    Bhanja, P.2    Liu, L.3    Alfieri, A.A.4    Yu, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.