메뉴 건너뛰기




Volumn 324, Issue 2, 2012, Pages 126-132

MAGE-A antigens as targets in tumour therapy

Author keywords

Drug targets; MAGE A; Melanoma antigen; RING finger proteins; Transcription factors

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; AZACITIDINE; CANCER VACCINE; MELANOMA ANTIGEN; MELANOMA ANTIGEN 1; MELANOMA ANTIGEN 2; MELANOMA ANTIGEN 3; MELANOMA ASSOCIATED ANTIGEN A; MELANOMA ASSOCIATED ANTIGEN A11; MELANOMA ASSOCIATED ANTIGEN C2; MELANOMA ASSOCIATED ANTIGEN G1; PROTEIN KAP1; PROTEIN MDM2; PROTEIN P53; REPRESSOR PROTEIN; TUMOR ANTIGEN; UNCLASSIFIED DRUG; VALPROIC ACID;

EID: 84864380076     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2012.05.011     Document Type: Review
Times cited : (79)

References (48)
  • 2
    • 0035879005 scopus 로고    scopus 로고
    • An overview of the MAGE gene family with the identification of all human members of the family
    • Chomez P., De Backer O., Bertrand M., De Plaen E., Boon T., Lucas S. An overview of the MAGE gene family with the identification of all human members of the family. Cancer Res. 2001, 61:5544-5551.
    • (2001) Cancer Res. , vol.61 , pp. 5544-5551
    • Chomez, P.1    De Backer, O.2    Bertrand, M.3    De Plaen, E.4    Boon, T.5    Lucas, S.6
  • 4
    • 54249136353 scopus 로고    scopus 로고
    • The melanoma-associated antigen A3 mediates fibronectin-controlled cancer progression and metastasis
    • Liu W., Cheng S., Asa S.L., Ezzat S. The melanoma-associated antigen A3 mediates fibronectin-controlled cancer progression and metastasis. Cancer Res. 2008, 68:8104-8112.
    • (2008) Cancer Res. , vol.68 , pp. 8104-8112
    • Liu, W.1    Cheng, S.2    Asa, S.L.3    Ezzat, S.4
  • 5
    • 79551703479 scopus 로고    scopus 로고
    • Androgen receptor molecular biology and potential targets in prostate cancer
    • Wilson E.M. Androgen receptor molecular biology and potential targets in prostate cancer. Ther. Adv. Urol. 2010, 2:105-117.
    • (2010) Ther. Adv. Urol. , vol.2 , pp. 105-117
    • Wilson, E.M.1
  • 6
    • 77956936946 scopus 로고    scopus 로고
    • MAGE-RING protein complexes comprise a family of E3 ubiquitin ligases
    • Doyle J.M., Gao J., Wang J., Yang M., Potts P.R. MAGE-RING protein complexes comprise a family of E3 ubiquitin ligases. Mol. Cell 2010, 39:963-974.
    • (2010) Mol. Cell , vol.39 , pp. 963-974
    • Doyle, J.M.1    Gao, J.2    Wang, J.3    Yang, M.4    Potts, P.R.5
  • 9
    • 0036813331 scopus 로고    scopus 로고
    • Cancer/testis antigens: an expanding family of targets for cancer immunotherapy
    • Scanlan M.J., Gure A.O., Jungbluth A.A., Old L.J., Chen Y.T. Cancer/testis antigens: an expanding family of targets for cancer immunotherapy. Immunol. Rev. 2002, 188:22-32.
    • (2002) Immunol. Rev. , vol.188 , pp. 22-32
    • Scanlan, M.J.1    Gure, A.O.2    Jungbluth, A.A.3    Old, L.J.4    Chen, Y.T.5
  • 12
    • 42149157253 scopus 로고    scopus 로고
    • Expression of MAGE and GAGE genes in medulloblastoma and modulation of resistance to chemotherapy. Laboratory investigation
    • Kasuga C., Nakahara Y., Ueda S., Hawkins C., Taylor M.D., Smith C.A., Rutka J.T. Expression of MAGE and GAGE genes in medulloblastoma and modulation of resistance to chemotherapy. Laboratory investigation. J. Neurosurg. Pediatr. 2008, 1:305-313.
    • (2008) J. Neurosurg. Pediatr. , vol.1 , pp. 305-313
    • Kasuga, C.1    Nakahara, Y.2    Ueda, S.3    Hawkins, C.4    Taylor, M.D.5    Smith, C.A.6    Rutka, J.T.7
  • 13
    • 33746610114 scopus 로고    scopus 로고
    • MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents
    • Monte M., Simonatto M., Peche L.Y., Bublik D.R., Gobessi S., Pierotti M.A., Rodolfo M., Schneider C. MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents. Proc. Natl. Acad. Sci. USA 2006, 103:11160-11165.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 11160-11165
    • Monte, M.1    Simonatto, M.2    Peche, L.Y.3    Bublik, D.R.4    Gobessi, S.5    Pierotti, M.A.6    Rodolfo, M.7    Schneider, C.8
  • 15
    • 0037206266 scopus 로고    scopus 로고
    • HMAGE-A1 overexpression reduces TNF-alpha cytotoxicity in ME-180 cells
    • Park J.H., Kong G.H., Lee S.W. HMAGE-A1 overexpression reduces TNF-alpha cytotoxicity in ME-180 cells. Mol. Cells 2002, 14:122-129.
    • (2002) Mol. Cells , vol.14 , pp. 122-129
    • Park, J.H.1    Kong, G.H.2    Lee, S.W.3
  • 17
    • 0032694084 scopus 로고    scopus 로고
    • DNA methylation is the primary silencing mechanism for a set of germ line- and tumor-specific genes with a CpG-rich promoter
    • De Smet C., Lurquin C., Lethe B., Martelange V., Boon T. DNA methylation is the primary silencing mechanism for a set of germ line- and tumor-specific genes with a CpG-rich promoter. Mol. Cell. Biol. 1999, 19:7327-7335.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 7327-7335
    • De Smet, C.1    Lurquin, C.2    Lethe, B.3    Martelange, V.4    Boon, T.5
  • 18
    • 33744829728 scopus 로고    scopus 로고
    • Promoter demethylation and histone acetylation mediate gene expression of MAGE-A1, -A2, -A3, and -A12 in human cancer cells
    • Wischnewski F., Pantel K., Schwarzenbach H. Promoter demethylation and histone acetylation mediate gene expression of MAGE-A1, -A2, -A3, and -A12 in human cancer cells. Mol. Cancer Res. 2006, 4:339-349.
    • (2006) Mol. Cancer Res. , vol.4 , pp. 339-349
    • Wischnewski, F.1    Pantel, K.2    Schwarzenbach, H.3
  • 19
    • 42249103085 scopus 로고    scopus 로고
    • Fibroblast growth factor 2 and estrogen control the balance of histone 3 modifications targeting MAGE-A3 in pituitary neoplasia
    • Zhu X., Asa S.L., Ezzat S. Fibroblast growth factor 2 and estrogen control the balance of histone 3 modifications targeting MAGE-A3 in pituitary neoplasia. Clin. Cancer Res. 2008, 14:1984-1996.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 1984-1996
    • Zhu, X.1    Asa, S.L.2    Ezzat, S.3
  • 20
    • 0037086294 scopus 로고    scopus 로고
    • The MAGE proteins: emerging roles in cell cycle progression, apoptosis, and neurogenetic disease
    • Barker P.A., Salehi A. The MAGE proteins: emerging roles in cell cycle progression, apoptosis, and neurogenetic disease. J. Neurosci. Res. 2002, 67:705-712.
    • (2002) J. Neurosci. Res. , vol.67 , pp. 705-712
    • Barker, P.A.1    Salehi, A.2
  • 21
    • 34548073030 scopus 로고    scopus 로고
    • The cancer/testis antigen melanoma-associated antigen-A3/A6 is a novel target of fibroblast growth factor receptor 2-IIIb through histone H3 modifications in thyroid cancer
    • Kondo T., Zhu X., Asa S.L., Ezzat S. The cancer/testis antigen melanoma-associated antigen-A3/A6 is a novel target of fibroblast growth factor receptor 2-IIIb through histone H3 modifications in thyroid cancer. Clin. Cancer Res. 2007, 13:4713-4720.
    • (2007) Clin. Cancer Res. , vol.13 , pp. 4713-4720
    • Kondo, T.1    Zhu, X.2    Asa, S.L.3    Ezzat, S.4
  • 24
    • 0033695190 scopus 로고    scopus 로고
    • NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin receptor and facilitates nerve growth factor-dependent apoptosis
    • Salehi A.H., Roux P.P., Kubu C.J., Zeindler C., Bhakar A., Tannis L.L., Verdi J.M., Barker P.A. NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin receptor and facilitates nerve growth factor-dependent apoptosis. Neuron 2000, 27:279-288.
    • (2000) Neuron , vol.27 , pp. 279-288
    • Salehi, A.H.1    Roux, P.P.2    Kubu, C.J.3    Zeindler, C.4    Bhakar, A.5    Tannis, L.L.6    Verdi, J.M.7    Barker, P.A.8
  • 25
    • 0035955631 scopus 로고    scopus 로고
    • Neurotrophin receptor-interacting mage homologue is an inducible inhibitor of apoptosis protein-interacting protein that augments cell death
    • Jordan B.W., Dinev D., LeMellay V., Troppmair J., Gotz R., Wixler L., Sendtner M., Ludwig S., Rapp U.R. Neurotrophin receptor-interacting mage homologue is an inducible inhibitor of apoptosis protein-interacting protein that augments cell death. J. Biol. Chem. 2001, 276:39985-39989.
    • (2001) J. Biol. Chem. , vol.276 , pp. 39985-39989
    • Jordan, B.W.1    Dinev, D.2    LeMellay, V.3    Troppmair, J.4    Gotz, R.5    Wixler, L.6    Sendtner, M.7    Ludwig, S.8    Rapp, U.R.9
  • 26
    • 0035966108 scopus 로고    scopus 로고
    • The trophinin gene encodes a novel group of MAGE proteins, magphinins, and regulates cell proliferation during gametogenesis in the mouse
    • Saburi S., Nadano D., Akama T.O., Hirama K., Yamanouchi K., Naito K., Tojo H., Tachi C., Fukuda M.N. The trophinin gene encodes a novel group of MAGE proteins, magphinins, and regulates cell proliferation during gametogenesis in the mouse. J. Biol. Chem. 2001, 276:49378-49389.
    • (2001) J. Biol. Chem. , vol.276 , pp. 49378-49389
    • Saburi, S.1    Nadano, D.2    Akama, T.O.3    Hirama, K.4    Yamanouchi, K.5    Naito, K.6    Tojo, H.7    Tachi, C.8    Fukuda, M.N.9
  • 27
    • 0033522919 scopus 로고    scopus 로고
    • Physical and functional interactions of neuronal growth suppressor necdin with p53
    • Taniura H., Matsumoto K., Yoshikawa K. Physical and functional interactions of neuronal growth suppressor necdin with p53. J. Biol. Chem. 1999, 274:16242-16248.
    • (1999) J. Biol. Chem. , vol.274 , pp. 16242-16248
    • Taniura, H.1    Matsumoto, K.2    Yoshikawa, K.3
  • 29
    • 80051858712 scopus 로고    scopus 로고
    • MAGE I transcription factors regulate KAP1 and KRAB domain zinc finger transcription factor mediated gene repression
    • Xiao T.Z., Bhatia N., Urrutia R., Lomberk G.A., Simpson A., Longley B.J. MAGE I transcription factors regulate KAP1 and KRAB domain zinc finger transcription factor mediated gene repression. PLoS One 2011, 6:e23747.
    • (2011) PLoS One , vol.6
    • Xiao, T.Z.1    Bhatia, N.2    Urrutia, R.3    Lomberk, G.A.4    Simpson, A.5    Longley, B.J.6
  • 30
    • 79953214941 scopus 로고    scopus 로고
    • When MAGE meets RING: insights into biological functions of MAGE proteins
    • Feng Y., Gao J., Yang M. When MAGE meets RING: insights into biological functions of MAGE proteins. Protein Cell 2011, 2:7-12.
    • (2011) Protein Cell , vol.2 , pp. 7-12
    • Feng, Y.1    Gao, J.2    Yang, M.3
  • 31
    • 78650390294 scopus 로고    scopus 로고
    • Mage-A cancer/testis antigens inhibit p53 function by blocking its interaction with chromatin
    • Marcar L., Maclaine N.J., Hupp T.R., Meek D.W. Mage-A cancer/testis antigens inhibit p53 function by blocking its interaction with chromatin. Cancer Res. 2010, 70:10362-10370.
    • (2010) Cancer Res. , vol.70 , pp. 10362-10370
    • Marcar, L.1    Maclaine, N.J.2    Hupp, T.R.3    Meek, D.W.4
  • 34
    • 84860709673 scopus 로고    scopus 로고
    • MageA2 restrains cellular senescence by targeting the function of PMLIV/p53 axis at the PML-NBs
    • Peche L.Y., Scolz M., Ladelfa M.F., Monte M., Schneider C. MageA2 restrains cellular senescence by targeting the function of PMLIV/p53 axis at the PML-NBs. Cell Death Differ. 2012, 19:926-936.
    • (2012) Cell Death Differ. , vol.19 , pp. 926-936
    • Peche, L.Y.1    Scolz, M.2    Ladelfa, M.F.3    Monte, M.4    Schneider, C.5
  • 36
    • 0030479071 scopus 로고    scopus 로고
    • A novel member of the RING finger family, KRIP-1, associates with the KRAB-A transcriptional repressor domain of zinc finger proteins
    • Kim S.S., Chen Y.M., O'Leary E., Witzgall R., Vidal M., Bonventre J.V. A novel member of the RING finger family, KRIP-1, associates with the KRAB-A transcriptional repressor domain of zinc finger proteins. Proc. Natl. Acad. Sci. USA 1996, 93:15299-15304.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 15299-15304
    • Kim, S.S.1    Chen, Y.M.2    O'Leary, E.3    Witzgall, R.4    Vidal, M.5    Bonventre, J.V.6
  • 37
    • 0030459738 scopus 로고    scopus 로고
    • Transcriptional repression by RING finger protein TIF1 beta that interacts with the KRAB repressor domain of KOX1
    • Moosmann P., Georgiev O., Le Douarin B., Bourquin J.P., Schaffner W. Transcriptional repression by RING finger protein TIF1 beta that interacts with the KRAB repressor domain of KOX1. Nucleic Acids Res. 1996, 24:4859-4867.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 4859-4867
    • Moosmann, P.1    Georgiev, O.2    Le Douarin, B.3    Bourquin, J.P.4    Schaffner, W.5
  • 38
    • 25144496653 scopus 로고    scopus 로고
    • MDM2 interaction with nuclear corepressor KAP1 contributes to p53 inactivation
    • Wang C., Ivanov A., Chen L., Fredericks W.J., Seto E., Rauscher F.J., Chen J. MDM2 interaction with nuclear corepressor KAP1 contributes to p53 inactivation. EMBO J. 2005, 24:3279-3290.
    • (2005) EMBO J. , vol.24 , pp. 3279-3290
    • Wang, C.1    Ivanov, A.2    Chen, L.3    Fredericks, W.J.4    Seto, E.5    Rauscher, F.J.6    Chen, J.7
  • 39
    • 70349438994 scopus 로고    scopus 로고
    • Tumour suppression by p53: a role for the DNA damage response?
    • Meek D.W. Tumour suppression by p53: a role for the DNA damage response?. Nat. Rev. Cancer 2009, 9:714-723.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 714-723
    • Meek, D.W.1
  • 40
    • 34748815649 scopus 로고    scopus 로고
    • GSK's antigen-specific cancer immunotherapy programme: pilot results leading to Phase III clinical development
    • Brichard V.G., Lejeune D. GSK's antigen-specific cancer immunotherapy programme: pilot results leading to Phase III clinical development. Vaccine 2007, 25(Suppl. 2):B61-B71.
    • (2007) Vaccine , vol.25 , Issue.SUPPL. 2
    • Brichard, V.G.1    Lejeune, D.2
  • 41
    • 47549093234 scopus 로고    scopus 로고
    • Cancer immunotherapy targeting tumour-specific antigens: towards a new therapy for minimal residual disease
    • Brichard V.G., Lejeune D. Cancer immunotherapy targeting tumour-specific antigens: towards a new therapy for minimal residual disease. Expert Opin. Biol. Ther. 2008, 8:951-968.
    • (2008) Expert Opin. Biol. Ther. , vol.8 , pp. 951-968
    • Brichard, V.G.1    Lejeune, D.2
  • 42
    • 59849122181 scopus 로고    scopus 로고
    • The cancer vaccine roller coaster
    • Goldman B., DeFrancesco L. The cancer vaccine roller coaster. Nat. Biotechnol. 2009, 27:129-139.
    • (2009) Nat. Biotechnol. , vol.27 , pp. 129-139
    • Goldman, B.1    DeFrancesco, L.2
  • 43
    • 79957709717 scopus 로고    scopus 로고
    • Vaccines for the treatment of non-small cell lung cancer: investigational approaches and clinical experience
    • Mellstedt H., Vansteenkiste J., Thatcher N. Vaccines for the treatment of non-small cell lung cancer: investigational approaches and clinical experience. Lung Cancer 2011, 73:11-17.
    • (2011) Lung Cancer , vol.73 , pp. 11-17
    • Mellstedt, H.1    Vansteenkiste, J.2    Thatcher, N.3
  • 44
    • 77956924038 scopus 로고    scopus 로고
    • Induction of a CD8+ T-cell response to the MAGE cancer testis antigen by combined treatment with azacitidine and sodium valproate in patients with acute myeloid leukemia and myelodysplasia
    • Goodyear O., Agathanggelou A., Novitzky-Basso I., Siddique S., McSkeane T., Ryan G., Vyas P., Cavenagh J., Stankovic T., Moss P., Craddock C. Induction of a CD8+ T-cell response to the MAGE cancer testis antigen by combined treatment with azacitidine and sodium valproate in patients with acute myeloid leukemia and myelodysplasia. Blood 2010, 116:1908-1918.
    • (2010) Blood , vol.116 , pp. 1908-1918
    • Goodyear, O.1    Agathanggelou, A.2    Novitzky-Basso, I.3    Siddique, S.4    McSkeane, T.5    Ryan, G.6    Vyas, P.7    Cavenagh, J.8    Stankovic, T.9    Moss, P.10    Craddock, C.11
  • 46
    • 78649808686 scopus 로고    scopus 로고
    • Stapled peptides in the p53 pathway: computer simulations reveal novel interactions of the staples with the target protein
    • Joseph T.L., Lane D., Verma C.S. Stapled peptides in the p53 pathway: computer simulations reveal novel interactions of the staples with the target protein. Cell Cycle 2010, 9:4560-4568.
    • (2010) Cell Cycle , vol.9 , pp. 4560-4568
    • Joseph, T.L.1    Lane, D.2    Verma, C.S.3
  • 47
    • 33845901313 scopus 로고    scopus 로고
    • MDM2 inhibitors for cancer therapy
    • Vassilev L.T. MDM2 inhibitors for cancer therapy. Trends Mol. Med. 2007, 13:23-31.
    • (2007) Trends Mol. Med. , vol.13 , pp. 23-31
    • Vassilev, L.T.1
  • 48
    • 79952673381 scopus 로고    scopus 로고
    • Identification of novel small molecules that inhibit protein-protein interactions between MAGE and KAP-1
    • Bhatia N., Yang B., Xiao T.Z., Peters N., Hoffmann M.F., Longley B.J. Identification of novel small molecules that inhibit protein-protein interactions between MAGE and KAP-1. Arch. Biochem. Biophys. 2011, 508:217-221.
    • (2011) Arch. Biochem. Biophys. , vol.508 , pp. 217-221
    • Bhatia, N.1    Yang, B.2    Xiao, T.Z.3    Peters, N.4    Hoffmann, M.F.5    Longley, B.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.