메뉴 건너뛰기




Volumn 136, Issue 7, 2013, Pages 2239-2252

In vivo characterization of the early states of the amyloid-beta network

Author keywords

Alzheimer's disease; amyloid; early stages; graph theory; network

Indexed keywords

AMYLOID BETA PROTEIN; PITTSBURGH COMPOUND B;

EID: 84879914396     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awt146     Document Type: Article
Times cited : (103)

References (110)
  • 1
    • 0033061647 scopus 로고    scopus 로고
    • Cerebrospinal fluid beta-Amyloid(1-42) in alzheimer disease: Differences between early-And late-onset alzheimer disease and stability during the course of disease
    • Andreasen N, Hesse C, Davidsson P, Minthon L, Wallin A, Winblad B, et al. Cerebrospinal fluid beta-Amyloid(1-42) in Alzheimer disease: Differences between early-And late-onset Alzheimer disease and stability during the course of disease. Arch Neurol 1999; 56: 673-80
    • (1999) Arch Neurol , vol.56 , pp. 673-680
    • Andreasen, N.1    Hesse, C.2    Davidsson, P.3    Minthon, L.4    Wallin, A.5    Winblad, B.6
  • 2
    • 0025717816 scopus 로고
    • The topographical and neuroanatomical distribution of neurofibrillary tangles and neuritic plaques in the cerebral cortex of patients with alzheimer's disease
    • Arnold SE, Hyman BT, Flory J, Damasio AR, Van Hoesen GW. The topographical and neuroanatomical distribution of neurofibrillary tangles and neuritic plaques in the cerebral cortex of patients with Alzheimer's disease. Cereb Cortex 1991; 1: 103-16
    • (1991) Cereb Cortex , vol.1 , pp. 103-116
    • Arnold, S.E.1    Hyman, B.T.2    Flory, J.3    Damasio, A.R.4    Van Hoesen, G.W.5
  • 3
    • 0142123057 scopus 로고    scopus 로고
    • Four-Dimensional multiphoton imaging of brain entry, amyloid binding, and clearance of an amyloid-beta ligand in transgenic mice
    • Bacskai BJ, Hickey GA, Skoch J, Kajdasz ST, Wang Y, Huang GF, et al. Four-Dimensional multiphoton imaging of brain entry, amyloid binding, and clearance of an amyloid-beta ligand in transgenic mice. Proc Natl Acad Sci USA 2003; 100: 12462-7
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 12462-12467
    • Bacskai, B.J.1    Hickey, G.A.2    Skoch, J.3    Kajdasz, S.T.4    Wang, Y.5    Huang, G.F.6
  • 4
    • 78650373804 scopus 로고    scopus 로고
    • Network medicine: A networkbased approach to human disease
    • Barabasi AL, Gulbahce N, Loscalzo J. Network medicine: A networkbased approach to human disease. Nat Rev Genet 2011; 12: 56-68
    • (2011) Nat Rev Genet , vol.12 , pp. 56-68
    • Barabasi, A.L.1    Gulbahce, N.2    Loscalzo, J.3
  • 6
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Benjamini Y, Hochberg Y. Controlling the false discovery rate: A practical and powerful approach to multiple testing. J R Statist Soc 1995; 57: 289-300
    • (1995) J R Statist Soc , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 7
    • 84859064398 scopus 로고    scopus 로고
    • Bidirectional relationship between functional connectivity and amyloidbeta deposition in mouse brain
    • Bero AW, Bauer AQ, Stewart FR, White BR, Cirrito JR, Raichle ME, et al. Bidirectional relationship between functional connectivity and amyloidbeta deposition in mouse brain. J Neurosci 2012; 32: 4334-40
    • (2012) J Neurosci , vol.32 , pp. 4334-4340
    • Bero, A.W.1    Bauer, A.Q.2    Stewart, F.R.3    White, B.R.4    Cirrito, J.R.5    Raichle, M.E.6
  • 8
    • 79960809092 scopus 로고    scopus 로고
    • Neuronal activity regulates the regional vulnerability to amyloid-beta deposition
    • Bero AW, Yan P, Roh JH, Cirrito JR, Stewart FR, Raichle ME, et al. Neuronal activity regulates the regional vulnerability to amyloid-beta deposition. Nat Neurosci 2011; 14: 750-6
    • (2011) Nat Neurosci , vol.14 , pp. 750-756
    • Bero, A.W.1    Yan, P.2    Roh, J.H.3    Cirrito, J.R.4    Stewart, F.R.5    Raichle, M.E.6
  • 9
    • 33746852686 scopus 로고    scopus 로고
    • Separating respiratoryvariation-related fluctuations from neuronal-Activity-related fluctuations in fMRI
    • Birn RM, Diamond JB, Smith MA, Bandettini PA. Separating respiratoryvariation-related fluctuations from neuronal-Activity-related fluctuations in fMRI. Neuroimage 2006; 31: 1536-48
    • (2006) Neuroimage , vol.31 , pp. 1536-1548
    • Birn, R.M.1    Diamond, J.B.2    Smith, M.A.3    Bandettini, P.A.4
  • 10
    • 0029166541 scopus 로고
    • Functional connectivity in the motor cortex of resting human brain using echo-planar MRI
    • Biswal B, Yetkin FZ, Haughton VM, Hyde JS. Functional connectivity in the motor cortex of resting human brain using echo-planar MRI. Magn Reson Med 1995; 34: 537-41
    • (1995) Magn Reson Med , vol.34 , pp. 537-541
    • Biswal, B.1    Yetkin, F.Z.2    Haughton, V.M.3    Hyde, J.S.4
  • 11
    • 33749150163 scopus 로고    scopus 로고
    • Staging of Alzheimer disease-Associated neurofibrillary pathology using paraffin sections and immunocytochemistry
    • Braak H, Alafuzoff I, Arzberger T, Kretzschmar H, Del Tredici K. Staging of Alzheimer disease-Associated neurofibrillary pathology using paraffin sections and immunocytochemistry. Acta Neuropathol 2006; 112: 389-404
    • (2006) Acta Neuropathol , vol.112 , pp. 389-404
    • Braak, H.1    Alafuzoff, I.2    Arzberger, T.3    Kretzschmar, H.4    Del Tredici, K.5
  • 12
    • 0026134421 scopus 로고
    • Demonstration of amyloid deposits and neurofibrillary changes in whole brain sections
    • Braak H, Braak E. Demonstration of amyloid deposits and neurofibrillary changes in whole brain sections. Brain Pathol 1991a; 1: 213-6
    • (1991) Brain Pathol , vol.1 , pp. 213-216
    • Braak, H.1    Braak, E.2
  • 13
    • 0025863618 scopus 로고
    • Neuropathological stageing of Alzheimer-related changes
    • Braak H, Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 1991b; 82: 239-59
    • (1991) Acta Neuropathol , vol.82 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 14
    • 0024371547 scopus 로고
    • Alzheimer's disease: Mismatch between amyloid plaques and neuritic plaques
    • Braak H, Braak E, Ohm T, Bohl J. Alzheimer's disease: Mismatch between amyloid plaques and neuritic plaques. Neurosci Lett 1989; 103: 24-8
    • (1989) Neurosci Lett , vol.103 , pp. 24-28
    • Braak, H.1    Braak, E.2    Ohm, T.3    Bohl, J.4
  • 16
    • 41949121294 scopus 로고    scopus 로고
    • The brain's default network: Anatomy, function, and relevance to disease
    • Buckner RL, Andrews-Hanna JR, Schacter DL. The brain's default network: Anatomy, function, and relevance to disease. Ann N Y Acad Sci 2008; 1124: 1-38
    • (2008) Ann N y Acad Sci , vol.1124 , pp. 1-38
    • Buckner, R.L.1    Andrews-Hanna, J.R.2    Schacter, D.L.3
  • 17
    • 60849136325 scopus 로고    scopus 로고
    • Cortical hubs revealed by intrinsic functional connectivity: Mapping, assessment of stability, and relation to Alzheimer's disease
    • Buckner RL, Sepulcre J, Talukdar T, Krienen FM, Liu H, Hedden T, et al. Cortical hubs revealed by intrinsic functional connectivity: Mapping, assessment of stability, and relation to Alzheimer's disease. J Neurosci 2009; 29: 1860-73
    • (2009) J Neurosci , vol.29 , pp. 1860-1873
    • Buckner, R.L.1    Sepulcre, J.2    Talukdar, T.3    Krienen, F.M.4    Liu, H.5    Hedden, T.6
  • 18
    • 60549103853 scopus 로고    scopus 로고
    • Complex brain networks: Graph theoretical analysis of structural and functional systems
    • Bullmore E, Sporns O. Complex brain networks: Graph theoretical analysis of structural and functional systems. Nat Rev Neurosci 2009; 10: 186-98
    • (2009) Nat Rev Neurosci , vol.10 , pp. 186-198
    • Bullmore, E.1    Sporns, O.2
  • 19
    • 0032402095 scopus 로고    scopus 로고
    • Alzheimer amyloid protein precursor in the rat hippocampus: Transport and processing through the perforant path
    • Buxbaum JD, Thinakaran G, Koliatsos V, O'Callahan J, Slunt HH, Price DL, et al. Alzheimer amyloid protein precursor in the rat hippocampus: Transport and processing through the perforant path. J Neurosci 1998; 18: 9629-37
    • (1998) J Neurosci , vol.18 , pp. 9629-9637
    • Buxbaum, J.D.1    Thinakaran, G.2    Koliatsos, V.3    O'Callahan, J.4    Slunt, H.H.5    Price, D.L.6
  • 23
    • 33749506795 scopus 로고    scopus 로고
    • Two-year follow-up of amyloid deposition in patients with Alzheimer's disease
    • Engler H, Forsberg A, Almkvist O, Blomquist G, Larsson E, Savitcheva I, et al. Two-year follow-up of amyloid deposition in patients with Alzheimer's disease. Brain 2006; 129: 2856-66
    • (2006) Brain , vol.129 , pp. 2856-2866
    • Engler, H.1    Forsberg, A.2    Almkvist, O.3    Blomquist, G.4    Larsson, E.5    Savitcheva, I.6
  • 24
    • 0025161935 scopus 로고
    • A quantitative study of the neurofibrillary tangles and the choline acetyltransferase activity in the cerebral cortex and the amygdala in Alzheimer's disease
    • Esiri MM, Pearson RC, Steele JE, Bowen DM, Powell TP. A quantitative study of the neurofibrillary tangles and the choline acetyltransferase activity in the cerebral cortex and the amygdala in Alzheimer's disease. J Neurol Neurosurg Psychiatry 1990; 53: 161-5
    • (1990) J Neurol Neurosurg Psychiatry , vol.53 , pp. 161-165
    • Esiri, M.M.1    Pearson, R.C.2    Steele, J.E.3    Bowen, D.M.4    Powell, T.P.5
  • 29
    • 52049121840 scopus 로고    scopus 로고
    • Resting-state functional connectivity in neuropsychiatric disorders
    • Greicius M. Resting-state functional connectivity in neuropsychiatric disorders. Curr Opin Neurol 2008; 21: 424-30
    • (2008) Curr Opin Neurol , vol.21 , pp. 424-430
    • Greicius, M.1
  • 30
    • 1842427969 scopus 로고    scopus 로고
    • Default-mode network activity distinguishes alzheimer's disease from healthy aging: Evidence from functional mri
    • Greicius MD, Srivastava G, Reiss AL, Menon V. Default-mode network activity distinguishes Alzheimer's disease from healthy aging: Evidence from functional MRI. Proc Natl Acad Sci USA 2004; 101: 4637-42
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 4637-4642
    • Greicius, M.D.1    Srivastava, G.2    Reiss, A.L.3    Menon, V.4
  • 31
    • 78049427912 scopus 로고    scopus 로고
    • Progression of cerebral amyloid load is associated with the apolipoprotein e epsilon4 genotype in Alzheimer's disease
    • Grimmer T, Tholen S, Yousefi BH, Alexopoulos P, Forschler A, Forstl H, et al. Progression of cerebral amyloid load is associated with the apolipoprotein E epsilon4 genotype in Alzheimer's disease. Biol Psychiatry 2010; 68: 879-84
    • (2010) Biol Psychiatry , vol.68 , pp. 879-884
    • Grimmer, T.1    Tholen, S.2    Yousefi, B.H.3    Alexopoulos, P.4    Forschler, A.5    Forstl, H.6
  • 32
    • 0035486838 scopus 로고    scopus 로고
    • Searching for a baseline: Functional imaging and the resting human brain
    • Gusnard DA, Raichle ME. Searching for a baseline: Functional imaging and the resting human brain. Nat Rev Neurosci 2001; 2: 685-94
    • (2001) Nat Rev Neurosci , vol.2 , pp. 685-694
    • Gusnard, D.A.1    Raichle, M.E.2
  • 33
    • 0026546599 scopus 로고
    • An ánatomical cascade hypo thesis' for alzheimer's disease
    • Hardy J. An ánatomical cascade hypothesis' for Alzheimer's disease. Trends Neurosci 1992; 15: 200-1
    • (1992) Trends Neurosci , vol.15 , pp. 200-201
    • Hardy, J.1
  • 34
    • 0026597063 scopus 로고
    • Alzheimer's disease: The amyloid cascade hypothesis
    • Hardy JA, Higgins GA. Alzheimer's disease: The amyloid cascade hypothesis. Science 1992; 256: 184-5
    • (1992) Science , vol.256 , pp. 184-185
    • Hardy, J.A.1    Higgins, G.A.2
  • 36
    • 70349876480 scopus 로고    scopus 로고
    • Disruption of functional connectivity in clinically normal older adults harboring amyloid burden
    • Hedden T, Van Dijk KR, Becker JA, Mehta A, Sperling RA, Johnson KA, et al. Disruption of functional connectivity in clinically normal older adults harboring amyloid burden. J Neurosci 2009; 29: 12686-94
    • (2009) J Neurosci , vol.29 , pp. 12686-12694
    • Hedden, T.1    Van Dijk, K.R.2    Becker, J.A.3    Mehta, A.4    Sperling, R.A.5    Johnson, K.A.6
  • 37
    • 0018928275 scopus 로고
    • Amygdaloid changes in aging and dementia
    • Herzog AG, Kemper TL. Amygdaloid changes in aging and dementia. Arch Neurol 1980; 37: 625-9
    • (1980) Arch Neurol , vol.37 , pp. 625-629
    • Herzog, A.G.1    Kemper, T.L.2
  • 39
    • 84856002055 scopus 로고    scopus 로고
    • National institute on aging-Alzheimer's association guidelines for the neuropathologic assessment of alzheimer's disease
    • Hyman BT, Phelps CH, Beach TG, Bigio EH, Cairns NJ, Carrillo MC, et al. National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease. Alzheimers Dement 2012; 8: 1-13
    • (2012) Alzheimers Dement , vol.8 , pp. 1-13
    • Hyman, B.T.1    Phelps, C.H.2    Beach, T.G.3    Bigio, E.H.4    Cairns, N.J.5    Carrillo, M.C.6
  • 40
    • 0021145680 scopus 로고
    • Alzheimer's disease: Cell-specific pathology isolates the hippocampal formation
    • Hyman BT, Van Hoesen GW, Damasio AR, Barnes CL. Alzheimer's disease: Cell-specific pathology isolates the hippocampal formation. Science 1984; 225: 1168-70
    • (1984) Science , vol.225 , pp. 1168-1170
    • Hyman, B.T.1    Van Hoesen, G.W.2    Damasio, A.R.3    Barnes, C.L.4
  • 41
    • 43849083580 scopus 로고    scopus 로고
    • Post-mortem correlates of in vivo pib-pet amyloid imaging in a typical case of alzheimer's disease
    • Ikonomovic MD, Klunk WE, Abrahamson EE, Mathis CA, Price JC, Tsopelas ND, et al. Post-mortem correlates of in vivo PIB-PET amyloid imaging in a typical case of Alzheimer's disease. Brain 2008; 131: 1630-45
    • (2008) Brain , vol.131 , pp. 1630-1645
    • Ikonomovic, M.D.1    Klunk, W.E.2    Abrahamson, E.E.3    Mathis, C.A.4    Price, J.C.5    Tsopelas, N.D.6
  • 43
    • 66549106850 scopus 로고    scopus 로고
    • Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer's disease: Implications for sequence of pathological events in Alzheimer's disease
    • Jack CR Jr, Lowe VJ, Weigand SD, Wiste HJ, Senjem ML, Knopman DS, et al. Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer's disease: Implications for sequence of pathological events in Alzheimer's disease. Brain 2009; 132: 1355-65
    • (2009) Brain , vol.132 , pp. 1355-1365
    • Jack Jr., C.R.1    Lowe, V.J.2    Weigand, S.D.3    Wiste, H.J.4    Senjem, M.L.5    Knopman, D.S.6
  • 45
    • 78650698306 scopus 로고    scopus 로고
    • Positron emission tomography imaging and clinical progression in relation to molecular pathology in the first pittsburgh compound b positron emission tomography patient with alzheimer's disease
    • Kadir A, Marutle A, Gonzalez D, Scholl M, Almkvist O, Mousavi M, et al. Positron emission tomography imaging and clinical progression in relation to molecular pathology in the first Pittsburgh Compound B positron emission tomography patient with Alzheimer's disease. Brain 2011; 134: 301-17
    • (2011) Brain , vol.134 , pp. 301-317
    • Kadir, A.1    Marutle, A.2    Gonzalez, D.3    Scholl, M.4    Almkvist, O.5    Mousavi, M.6
  • 46
    • 0024380601 scopus 로고
    • The presubicular region in Alzheimer's disease: Topography of amyloid deposits and neurofibrillary changes
    • Kalus P, Braak H, Braak E, Bohl J. The presubicular region in Alzheimer's disease: Topography of amyloid deposits and neurofibrillary changes. Brain Res 1989; 494: 198-203
    • (1989) Brain Res , vol.494 , pp. 198-203
    • Kalus, P.1    Braak, H.2    Braak, E.3    Bohl, J.4
  • 49
    • 34248231779 scopus 로고    scopus 로고
    • PET amyloid ligand [11C] PIB uptake is increased in mild cognitive impairment
    • Kemppainen NM, Aalto S, Wilson IA, Nagren K, Helin S, Bruck A, et al. PET amyloid ligand [11C]PIB uptake is increased in mild cognitive impairment. Neurology 2007; 68: 1603-6
    • (2007) Neurology , vol.68 , pp. 1603-1606
    • Kemppainen, N.M.1    Aalto, S.2    Wilson, I.A.3    Nagren, K.4    Helin, S.5    Bruck, A.6
  • 51
    • 0035902875 scopus 로고    scopus 로고
    • Uncharged thioflavin-T derivatives bind to amyloid-beta protein with high affinity and readily enter the brain
    • Klunk WE, Wang Y, Huang GF, Debnath ML, Holt DP, Mathis CA. Uncharged thioflavin-T derivatives bind to amyloid-beta protein with high affinity and readily enter the brain. Life Sci 2001; 69: 1471-84
    • (2001) Life Sci , vol.69 , pp. 1471-1484
    • Klunk, W.E.1    Wang, Y.2    Huang, G.F.3    Debnath, M.L.4    Holt, D.P.5    Mathis, C.A.6
  • 52
    • 79953177902 scopus 로고    scopus 로고
    • Amyloid PET imaging in patients with mild cognitive impairment: A 2-year follow-up study
    • Koivunen J, Scheinin N, Virta JR, Aalto S, Vahlberg T, Nagren K, et al. Amyloid PET imaging in patients with mild cognitive impairment: A 2-year follow-up study. Neurology 2011; 76: 1085-90
    • (2011) Neurology , vol.76 , pp. 1085-1090
    • Koivunen, J.1    Scheinin, N.2    Virta, J.R.3    Aalto, S.4    Vahlberg, T.5    Nagren, K.6
  • 54
    • 0037111837 scopus 로고    scopus 로고
    • Evidence that synaptically released beta-Amyloid accumulates as extracellular deposits in the hippocampus of transgenic mice
    • Lazarov O, Lee M, Peterson DA, Sisodia SS. Evidence that synaptically released beta-Amyloid accumulates as extracellular deposits in the hippocampus of transgenic mice. J Neurosci 2002; 22: 9785-93
    • (2002) J Neurosci , vol.22 , pp. 9785-9793
    • Lazarov, O.1    Lee, M.2    Peterson, D.A.3    Sisodia, S.S.4
  • 55
    • 0023222380 scopus 로고
    • Laminar and regional distributions of neurofibrillary tangles and neuritic plaques in Alzheimer's disease: A quantitative study of visual and auditory cortices
    • Lewis DA, Campbell MJ, Terry RD, Morrison JH. Laminar and regional distributions of neurofibrillary tangles and neuritic plaques in Alzheimer's disease: A quantitative study of visual and auditory cortices. J Neurosci 1987; 7: 1799-808
    • (1987) J Neurosci , vol.7 , pp. 1799-1808
    • Lewis, D.A.1    Campbell, M.J.2    Terry, R.D.3    Morrison, J.H.4
  • 56
    • 0025127930 scopus 로고
    • Graphical analysis of reversible radioligand binding from time-Activity measurements applied to [N-11C-methyl]-(-)-cocaine PET studies in human subjects
    • Logan J, Fowler JS, Volkow ND, Wolf AP, Dewey SL, Schlyer DJ, et al. Graphical analysis of reversible radioligand binding from time-Activity measurements applied to [N-11C-methyl]-(-)-cocaine PET studies in human subjects. J Cereb Blood Flow Metab 1990; 10: 740-7
    • (1990) J Cereb Blood Flow Metab , vol.10 , pp. 740-747
    • Logan, J.1    Fowler, J.S.2    Volkow, N.D.3    Wolf, A.P.4    Dewey, S.L.5    Schlyer, D.J.6
  • 57
    • 33644876596 scopus 로고    scopus 로고
    • Simplified quantification of Pittsburgh Compound B amyloid imaging PET studies: A comparative analysis
    • Lopresti BJ, Klunk WE, Mathis CA, Hoge JA, Ziolko SK, Lu X, et al. Simplified quantification of Pittsburgh Compound B amyloid imaging PET studies: A comparative analysis. J Nucl Med 2005; 46: 1959-72
    • (2005) J Nucl Med , vol.46 , pp. 1959-1972
    • Lopresti, B.J.1    Klunk, W.E.2    Mathis, C.A.3    Hoge, J.A.4    Ziolko, S.K.5    Lu, X.6
  • 59
    • 0028260083 scopus 로고
    • Senile plaques in temporal lobe epilepsy
    • Mackenzie IR, Miller LA. Senile plaques in temporal lobe epilepsy. Acta Neuropathol 1994; 87: 504-10
    • (1994) Acta Neuropathol , vol.87 , pp. 504-510
    • MacKenzie, I.R.1    Miller, L.A.2
  • 60
    • 0022414320 scopus 로고
    • The neuropathology of Alzheimer's disease: A review with pathogenetic, aetiological and therapeutic considerations
    • Mann DM. The neuropathology of Alzheimer's disease: A review with pathogenetic, aetiological and therapeutic considerations. Mech Ageing Dev 1985; 31: 213-55
    • (1985) Mech Ageing Dev , vol.31 , pp. 213-255
    • Mann, D.M.1
  • 61
    • 0023225114 scopus 로고
    • The topographic distribution of senile plaques and neurofibrillary tangles in the brains of non-Demented persons of different ages
    • Mann DM, Tucker CM, Yates PO. The topographic distribution of senile plaques and neurofibrillary tangles in the brains of non-Demented persons of different ages. Neuropathol Appl Neurobiol 1987; 13: 123-39
    • (1987) Neuropathol Appl Neurobiol , vol.13 , pp. 123-139
    • Mann, D.M.1    Tucker, C.M.2    Yates, P.O.3
  • 63
    • 0038792263 scopus 로고    scopus 로고
    • Synthesis and evaluation of 11C-labeled 6-substituted 2-Arylbenzothiazoles as amyloid imaging agents
    • Mathis CA, Wang Y, Holt DP, Huang GF, Debnath ML, Klunk WE. Synthesis and evaluation of 11C-labeled 6-substituted 2-Arylbenzothiazoles as amyloid imaging agents. J Med Chem 2003; 46: 2740-54
    • (2003) J Med Chem , vol.46 , pp. 2740-2754
    • Mathis, C.A.1    Wang, Y.2    Holt, D.P.3    Huang, G.F.4    Debnath, M.L.5    Klunk, W.E.6
  • 64
    • 3943092621 scopus 로고    scopus 로고
    • Pathways towards and away from Alzheimer's disease
    • Mattson MP. Pathways towards and away from Alzheimer's disease. Nature 2004; 430: 631-9
    • (2004) Nature , vol.430 , pp. 631-639
    • Mattson, M.P.1
  • 65
    • 0021271971 scopus 로고
    • Clinical diagnosis of alzheimer's disease: Report of the nincdsadrda work group under the auspices of department of health and human services task force on alzheimer's disease
    • McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: Report of the NINCDSADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984; 34: 939-44
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3    Katzman, R.4    Price, D.5    Stadlan, E.M.6
  • 66
    • 0021319490 scopus 로고
    • Neural inputs into the nucleus basalis of the substantia innominata (Ch4) in the rhesus monkey
    • Mesulam MM, Mufson EJ. Neural inputs into the nucleus basalis of the substantia innominata (Ch4) in the rhesus monkey. Brain 1984; 107 (Pt 1): 253-74
    • (1984) Brain , vol.107 , Issue.PART 1 , pp. 253-274
    • Mesulam, M.M.1    Mufson, E.J.2
  • 67
    • 0030874251 scopus 로고    scopus 로고
    • Metabolic reduction in the posterior cingulate cortex in very early Alzheimer's disease
    • Minoshima S, Giordani B, Berent S, Frey KA, Foster NL, Kuhl DE. Metabolic reduction in the posterior cingulate cortex in very early Alzheimer's disease. Ann Neurol 1997; 42: 85-94
    • (1997) Ann Neurol , vol.42 , pp. 85-94
    • Minoshima, S.1    Giordani, B.2    Berent, S.3    Frey, K.A.4    Foster, N.L.5    Kuhl, D.E.6
  • 68
    • 33747048954 scopus 로고    scopus 로고
    • 11c] pib in a nondemented population: Potential antecedent marker of alzheimer disease
    • Mintun MA, Larossa GN, Sheline YI, Dence CS, Lee SY, Mach RH, et al. [11C]PIB in a nondemented population: Potential antecedent marker of Alzheimer disease. Neurology 2006; 67: 446-52
    • (2006) Neurology , vol.67 , pp. 446-452
    • Mintun, M.A.1    Larossa, G.N.2    Sheline, Y.I.3    Dence, C.S.4    Lee, S.Y.5    MacH, R.H.6
  • 69
    • 0027425211 scopus 로고
    • The Clinical Dementia Rating (CDR): Current version and scoring rules
    • Morris JC. The Clinical Dementia Rating (CDR): Current version and scoring rules. Neurology 1993; 43: 2412-4.
    • (1993) Neurology , vol.43 , pp. 2412-2414
    • Morris, J.C.1
  • 70
    • 73549092137 scopus 로고    scopus 로고
    • Pittsburgh Compound B imaging and prediction of progression from cognitive normality to symptomatic Alzheimer disease
    • Morris JC, Roe CM, Grant EA, Head D, Storandt M, Goate AM, et al. Pittsburgh Compound B imaging and prediction of progression from cognitive normality to symptomatic Alzheimer disease. Arch Neurol 2009; 66: 1469-75
    • (2009) Arch Neurol , vol.66 , pp. 1469-1475
    • Morris, J.C.1    Roe, C.M.2    Grant, E.A.3    Head, D.4    Storandt, M.5    Goate, A.M.6
  • 71
    • 0027209083 scopus 로고
    • Release of amyloid beta-protein precursor derivatives by electrical depolarization of rat hippocampal slices
    • Nitsch RM, Farber SA, Growdon JH, Wurtman RJ. Release of amyloid beta-protein precursor derivatives by electrical depolarization of rat hippocampal slices. Proc Natl Acad Sci USA 1993; 90: 5191-3
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 5191-5193
    • Nitsch, R.M.1    Farber, S.A.2    Growdon, J.H.3    Wurtman, R.J.4
  • 72
    • 4644283049 scopus 로고    scopus 로고
    • PET imaging of amyloid in Alzheimer's disease
    • Nordberg A. PET imaging of amyloid in Alzheimer's disease. Lancet Neurol 2004; 3: 519-27
    • (2004) Lancet Neurol , vol.3 , pp. 519-527
    • Nordberg, A.1
  • 73
    • 0024601426 scopus 로고
    • Betaprotein amyloid is widely distributed in the central nervous system of patients with Alzheimer's disease
    • Ogomori K, Kitamoto T, Tateishi J, Sato Y, Suetsugu M, Abe M. Betaprotein amyloid is widely distributed in the central nervous system of patients with Alzheimer's disease. Am J Pathol 1989; 134: 243-51
    • (1989) Am J Pathol , vol.134 , pp. 243-251
    • Ogomori, K.1    Kitamoto, T.2    Tateishi, J.3    Sato, Y.4    Suetsugu, M.5    Abe, M.6
  • 74
    • 0022521048 scopus 로고
    • Excitatory amino acid-releasing and cholinergic neurones in Alzheimer's disease
    • Palmer AM, Procter AW, Stratmann GC, Bowen DM. Excitatory amino acid-releasing and cholinergic neurones in Alzheimer's disease. Neurosci Lett 1986; 66: 199-204
    • (1986) Neurosci Lett , vol.66 , pp. 199-204
    • Palmer, A.M.1    Procter, A.W.2    Stratmann, G.C.3    Bowen, D.M.4
  • 75
    • 33750339228 scopus 로고    scopus 로고
    • A network dysfunction perspective on neurodegenerative diseases
    • Palop JJ, Chin J, Mucke L. A network dysfunction perspective on neurodegenerative diseases. Nature 2006; 443: 768-73
    • (2006) Nature , vol.443 , pp. 768-773
    • Palop, J.J.1    Chin, J.2    Mucke, L.3
  • 76
    • 77954132249 scopus 로고    scopus 로고
    • Amyloid-beta-induced neuronal dysfunction in alzheimer's disease: From synapses toward neural networks
    • Palop JJ, Mucke L. Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: From synapses toward neural networks. Nat Neurosci 2010; 13: 812-8
    • (2010) Nat Neurosci , vol.13 , pp. 812-818
    • Palop, J.J.1    Mucke, L.2
  • 77
    • 0024369761 scopus 로고
    • The neuroanatomy of Alzheimer's disease
    • Pearson RC, Powell TP. The neuroanatomy of Alzheimer's disease. Rev Neurosci 1989; 2: 101-22
    • (1989) Rev Neurosci , vol.2 , pp. 101-122
    • Pearson, R.C.1    Powell, T.P.2
  • 78
    • 72049120104 scopus 로고    scopus 로고
    • Alzheimer's disease: Progress in prediction
    • Petersen RC. Alzheimer's disease: Progress in prediction. Lancet Neurol 2010; 9: 4-5
    • (2010) Lancet Neurol , vol.9 , pp. 4-5
    • Petersen, R.C.1
  • 79
    • 80053383653 scopus 로고    scopus 로고
    • Amygdala atrophy is prominent in early Alzheimer's disease and relates to symptom severity
    • Poulin SP, Dautoff R, Morris JC, Barrett LF, Dickerson BC. Amygdala atrophy is prominent in early Alzheimer's disease and relates to symptom severity. Psychiatry Res 2011; 194: 7-13
    • (2011) Psychiatry Res , vol.194 , pp. 7-13
    • Poulin, S.P.1    Dautoff, R.2    Morris, J.C.3    Barrett, L.F.4    Dickerson, B.C.5
  • 80
    • 84858648349 scopus 로고    scopus 로고
    • A network diffusion model of disease progression in dementia
    • Raj A, Kuceyeski A, Weiner M. A network diffusion model of disease progression in dementia. Neuron 2012; 73: 1204-15
    • (2012) Neuron , vol.73 , pp. 1204-1215
    • Raj, A.1    Kuceyeski, A.2    Weiner, M.3
  • 83
    • 85039793023 scopus 로고    scopus 로고
    • A tangled web (eletters
    • Royall DR. A Tangled Web (eLetters). J Neurosci 2010; 29: 1860-73
    • (2010) J Neurosci , vol.29 , pp. 1860-1873
    • Royall, D.R.1
  • 84
    • 84867307852 scopus 로고    scopus 로고
    • The association between a polygenic Alzheimer score and cortical thickness in clinically normal subjects
    • Sabuncu MR, Buckner RL, Smoller JW, Lee PH, Fischl B, Sperling RA. The association between a polygenic Alzheimer score and cortical thickness in clinically normal subjects. Cereb Cortex 2012; 22: 2653-61
    • (2012) Cereb Cortex , vol.22 , pp. 2653-2661
    • Sabuncu, M.R.1    Buckner, R.L.2    Smoller, J.W.3    Lee, P.H.4    Fischl, B.5    Sperling, R.A.6
  • 86
    • 0023473468 scopus 로고
    • Axonal and transneuronal transport in the transmission of neurological disease: Potential role in system degenerations, including alzheimer's disease
    • Saper CB, Wainer BH, German DC. Axonal and transneuronal transport in the transmission of neurological disease: Potential role in system degenerations, including Alzheimer's disease. Neuroscience 1987; 23: 389-98
    • (1987) Neuroscience , vol.23 , pp. 389-398
    • Saper, C.B.1    Wainer, B.H.2    German, D.C.3
  • 88
    • 33745923170 scopus 로고    scopus 로고
    • The ups and downs of Abeta
    • Selkoe DJ. The ups and downs of Abeta. Nat Med 2006; 12: 758-9; discussion 759
    • (2006) Nat Med , vol.12 , pp. 758-759
    • Selkoe, D.J.1
  • 91
    • 84863724428 scopus 로고    scopus 로고
    • Stepwise connectivity of the modal cortex reveals the multimodal organization of the human brain
    • Sepulcre J, Sabuncu MR, Yeo TB, Liu H, Johnson KA. Stepwise connectivity of the modal cortex reveals the multimodal organization of the human brain. J Neurosci 2012b; 32: 10649-61
    • (2012) J Neurosci , vol.32 , pp. 10649-10661
    • Sepulcre, J.1    Sabuncu, M.R.2    Yeo, T.B.3    Liu, H.4    Johnson, K.A.5
  • 92
    • 79955768543 scopus 로고    scopus 로고
    • Longitudinal patterns of beta-Amyloid deposition in nondemented older adults
    • Sojkova J, Zhou Y, An Y, Kraut MA, Ferrucci L, Wong DF, et al. Longitudinal patterns of beta-Amyloid deposition in nondemented older adults. Arch Neurol 2011; 68: 644-9
    • (2011) Arch Neurol , vol.68 , pp. 644-649
    • Sojkova, J.1    Zhou, Y.2    An, Y.3    Kraut, M.A.4    Ferrucci, L.5    Wong, D.F.6
  • 93
    • 79956098248 scopus 로고    scopus 로고
    • Toward defining the preclinical stages of alzheimer's disease: Recommendations from the national institute on aging-Alzheimer's association workgroups on diagnostic guidelines for alzheimer's disease
    • Sperling RA, Aisen PS, Beckett LA, Bennett DA, Craft S, Fagan AM, et al. Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 2011; 7: 280-92
    • (2011) Alzheimers Dement , vol.7 , pp. 280-292
    • Sperling, R.A.1    Aisen, P.S.2    Beckett, L.A.3    Bennett, D.A.4    Craft, S.5    Fagan, A.M.6
  • 94
    • 67650875899 scopus 로고    scopus 로고
    • Amyloid deposition is associated with impaired default network function in older persons without dementia
    • Sperling RA, Laviolette PS, O'Keefe K, O'Brien J, Rentz DM, Pihlajamaki M, et al. Amyloid deposition is associated with impaired default network function in older persons without dementia. Neuron 2009; 63: 178-88
    • (2009) Neuron , vol.63 , pp. 178-188
    • Sperling, R.A.1    Laviolette, P.S.2    O'Keefe, K.3    O'Brien, J.4    Rentz, D.M.5    Pihlajamaki, M.6
  • 95
    • 4444318641 scopus 로고    scopus 로고
    • Organization, development and function of complex brain networks
    • Sporns O, Chialvo DR, Kaiser M, Hilgetag CC. Organization, development and function of complex brain networks. Trends Cogn Sci 2004; 8: 418-25
    • (2004) Trends Cogn Sci , vol.8 , pp. 418-425
    • Sporns, O.1    Chialvo, D.R.2    Kaiser, M.3    Hilgetag, C.C.4
  • 96
    • 0037172826 scopus 로고    scopus 로고
    • Phases of A beta-Deposition in the human brain and its relevance for the development of AD
    • Thal DR, Rub U, Orantes M, Braak H. Phases of A beta-Deposition in the human brain and its relevance for the development of AD. Neurology 2002; 58: 1791-800
    • (2002) Neurology , vol.58 , pp. 1791-1800
    • Thal, D.R.1    Rub, U.2    Orantes, M.3    Braak, H.4
  • 97
    • 79953647082 scopus 로고    scopus 로고
    • Spatial patterns of brain amyloid-beta burden and atrophy rate associations in mild cognitive impairment
    • Tosun D, Schuff N, Mathis CA, Jagust W, Weiner MW. Spatial patterns of brain amyloid-beta burden and atrophy rate associations in mild cognitive impairment. Brain 2011; 134: 1077-88
    • (2011) Brain , vol.134 , pp. 1077-1088
    • Tosun, D.1    Schuff, N.2    Mathis, C.A.3    Jagust, W.4    Weiner, M.W.5
  • 98
    • 0036322886 scopus 로고    scopus 로고
    • Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI singlesubject brain
    • Tzourio-Mazoyer N, Landeau B, Papathanassiou D, Crivello F, Etard O, Delcroix N, et al. Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI singlesubject brain. Neuroimage 2002; 15: 273-89
    • (2002) Neuroimage , vol.15 , pp. 273-289
    • Tzourio-Mazoyer, N.1    Landeau, B.2    Papathanassiou, D.3    Crivello, F.4    Etard, O.5    Delcroix, N.6
  • 99
    • 74049156284 scopus 로고    scopus 로고
    • Intrinsic functional connectivity as a tool for human connectomics: Theory, properties, and optimization
    • Van Dijk KR, Hedden T, Venkataraman A, Evans KC, Lazar SW, Buckner RL. Intrinsic functional connectivity as a tool for human connectomics: Theory, properties, and optimization. J Neurophysiol 2010; 103: 297-321
    • (2010) J Neurophysiol , vol.103 , pp. 297-321
    • Van Dijk, K.R.1    Hedden, T.2    Venkataraman, A.3    Evans, K.C.4    Lazar, S.W.5    Buckner, R.L.6
  • 100
    • 36348988250 scopus 로고    scopus 로고
    • Surface-based and probabilistic atlases of primate cerebral cortex
    • Van Essen DC, Dierker DL. Surface-based and probabilistic atlases of primate cerebral cortex. Neuron 2007; 56: 209-25
    • (2007) Neuron , vol.56 , pp. 209-225
    • Van Essen, D.C.1    Dierker, D.L.2
  • 101
    • 84863198003 scopus 로고    scopus 로고
    • Regional dynamics of amyloid-beta deposition in healthy elderly, mild cognitive impairment and Alzheimer's disease: A voxelwise PIB-PET longitudinal study
    • Villain N, Chetelat G, Grassiot B, Bourgeat P, Jones G, Ellis KA, et al. Regional dynamics of amyloid-beta deposition in healthy elderly, mild cognitive impairment and Alzheimer's disease: A voxelwise PIB-PET longitudinal study. Brain 2012; 135 (Pt 7): 2126-39
    • (2012) Brain , vol.135 , Issue.PART 7 , pp. 2126-2139
    • Villain, N.1    Chetelat, G.2    Grassiot, B.3    Bourgeat, P.4    Jones, G.5    Ellis, K.A.6
  • 102
    • 78049472063 scopus 로고    scopus 로고
    • Sequential relationships between grey matter and white matter atrophy and brain metabolic abnormalities in early Alzheimer's disease
    • Villain N, Fouquet M, Baron JC, Mezenge F, Landeau B, de La Sayette V, et al. Sequential relationships between grey matter and white matter atrophy and brain metabolic abnormalities in early Alzheimer's disease. Brain 2010; 133: 3301-14
    • (2010) Brain , vol.133 , pp. 3301-3314
    • Villain, N.1    Fouquet, M.2    Baron, J.C.3    Mezenge, F.4    Landeau, B.5    De La Sayette, V.6
  • 104
    • 83255181779 scopus 로고    scopus 로고
    • Amyloid-beta plaque growth in cognitively normal adults: Longitudinal [11c] pittsburgh compound b data
    • Vlassenko AG, Mintun MA, Xiong C, Sheline YI, Goate AM, Benzinger TL, et al. Amyloid-beta plaque growth in cognitively normal adults: Longitudinal [11C]Pittsburgh compound B data. Ann Neurol 2011; 70: 857-61
    • (2011) Ann Neurol , vol.70 , pp. 857-861
    • Vlassenko, A.G.1    Mintun, M.A.2    Xiong, C.3    Sheline, Y.I.4    Goate, A.M.5    Benzinger, T.L.6
  • 106
    • 84892680540 scopus 로고    scopus 로고
    • Mechanisms of protein seeding in neurodegenerative diseases
    • Walker LC, Diamond MI, Duff KE, Hyman BT. Mechanisms of protein seeding in neurodegenerative diseases. Arch Neurol 2012; 10: 1-7
    • (2012) Arch Neurol , vol.10 , pp. 1-7
    • Walker, L.C.1    Diamond, M.I.2    Duff, K.E.3    Hyman, B.T.4
  • 107
    • 2542427690 scopus 로고    scopus 로고
    • Oligomers on the brain: The emerging role of soluble protein aggregates in neurodegeneration
    • Walsh DM, Selkoe DJ. Oligomers on the brain: The emerging role of soluble protein aggregates in neurodegeneration. Protein Pept Lett 2004; 11: 213-28
    • (2004) Protein Pept Lett , vol.11 , pp. 213-228
    • Walsh, D.M.1    Selkoe, D.J.2
  • 109
  • 110
    • 84863337784 scopus 로고    scopus 로고
    • Predicting regional neurodegeneration from the healthy brain functional connectome
    • Zhou J, Gennatas ED, Kramer JH, Miller BL, Seeley WW. Predicting regional neurodegeneration from the healthy brain functional connectome. Neuron 2012; 73: 1216-27
    • (2012) Neuron , vol.73 , pp. 1216-1227
    • Zhou, J.1    Gennatas, E.D.2    Kramer, J.H.3    Miller, B.L.4    Seeley, W.W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.