Nanomolar e-selectin antagonists with prolonged half-lives by a fragment-based approach

Journal of the American Chemical Society

Volumn 135, Issue 26, 2013, Pages 9820-9828

  Egger, Jonas ^a   Weckerle, Céline ^a   Cutting, Brian ^a   Schwardt, Oliver ^a   Rabbani, Said ^a   Lemme, Katrin ^a   Ernst, Beat ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-INFLAMMATORY DRUGS; C-TYPE LECTINS; CLOSE PROXIMITY; E-SELECTIN ANTAGONIST; INFLAMMATORY DISEASE; SIALYL LEWIS X; TETRASACCHARIDES; THERAPEUTIC APPLICATION;

DISEASES; PROTEINS;

LIGANDS;

CARBOHYDRATE; E SELECTIN ANTAGONIST; LECTIN; LIGAND; SELECTIN ANTAGONIST; SIALYL LEWIS X ANTIGEN; TRIAZOLE; UNCLASSIFIED DRUG;

ARTICLE; CLICK CHEMISTRY; CYCLOADDITION; DERIVATIZATION; DRUG HALF LIFE; FRAGMENTATION REACTION; HYDROGEN BOND; NUCLEAR MAGNETIC RESONANCE; SPIN LABELING; SURFACE PLASMON RESONANCE;

E-SELECTIN; MOLECULAR CONFORMATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR;

EID: 84879768571     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja4029582     Document Type: Article

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