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Volumn 45, Issue 7, 2013, Pages 739-746

Zbtb7a suppresses prostate cancer through repression of a Sox9-dependent pathway for cellular senescence bypass and tumor invasion

(19)  Wang, Guocan a,b,c   Lunardi, Andrea a   Zhang, Jiangwen d   Chen, Zhenbang c,g   Ala, Ugo a   Webster, Kaitlyn A a   Tay, Yvonne a   Gonzalez Billalabeitia, Enrique a   Egia, Ainara a   Shaffer, David R c,h   Carver, Brett c   Liu, Xue Song a   Taulli, Riccardo a   Kuo, Winston Patrick e   Nardella, Caterina a,c   Signoretti, Sabina a,f   Cordon Cardo, Carlos c,i   Gerald, William L c   Pandolfi, Pier Paolo a,c  


Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; MICRORNA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; TRANSCRIPTION FACTOR SOX9;

EID: 84879645484     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.2654     Document Type: Article
Times cited : (123)

References (75)
  • 1
    • 12744269233 scopus 로고    scopus 로고
    • Role of the proto-oncogene Pokemon in cellular transformation and ARF repression
    • Maeda, T. et al. Role of the proto-oncogene Pokemon in cellular transformation and ARF repression. Nature 433, 278-285 (2005).
    • (2005) Nature , vol.433 , pp. 278-285
    • Maeda, T.1
  • 2
    • 0036196574 scopus 로고    scopus 로고
    • FBI-1 can stimulate HIV-1 Tat activity and is targeted to a novel subnuclear domain that includes the Tat-P-TEFb-containing nuclear speckles
    • Pendergrast, P.S., Wang, C., Hernandez, N. & Huang, S. FBI-1 can stimulate HIV-1 Tat activity and is targeted to a novel subnuclear domain that includes the Tat-P-TEFb-containing nuclear speckles. Mol. Biol. Cell 13, 915-929 (2002).
    • (2002) Mol. Biol. Cell , vol.13 , pp. 915-929
    • Pendergrast, P.S.1    Wang, C.2    Hernandez, N.3    Huang, S.4
  • 3
    • 0033568579 scopus 로고    scopus 로고
    • Osteoclast-derived zinc finger (OCZF) protein with POZ domain, a possible transcriptional repressor, is involved in osteoclastogenesis
    • Kukita, A. et al. Osteoclast-derived zinc finger (OCZF) protein with POZ domain, a possible transcriptional repressor, is involved in osteoclastogenesis. Blood 94, 1987-1997 (1999).
    • (1999) Blood , vol.94 , pp. 1987-1997
    • Kukita, A.1
  • 4
    • 0033552908 scopus 로고    scopus 로고
    • Novel BTB/POZ domain zinc-finger protein, LRF, is a potential target of the LAZ-3/BCL-6 oncogene
    • Davies, J.M. et al. Novel BTB/POZ domain zinc-finger protein, LRF, is a potential target of the LAZ-3/BCL-6 oncogene. Oncogene 18, 365-375 (1999).
    • (1999) Oncogene , vol.18 , pp. 365-375
    • Davies, J.M.1
  • 5
    • 0037459050 scopus 로고    scopus 로고
    • Transcriptional profiling of Kruppel-like factor 4 reveals a function in cell cycle regulation and epithelial differentiation
    • Chen, X., Whitney, E.M., Gao, S.Y. & Yang, V.W. Transcriptional profiling of Kruppel-like factor 4 reveals a function in cell cycle regulation and epithelial differentiation. J. Mol. Biol. 326, 665-677 (2003).
    • (2003) J. Mol. Biol. , vol.326 , pp. 665-677
    • Chen, X.1    Whitney, E.M.2    Gao, S.Y.3    Yang, V.W.4
  • 6
    • 2642550555 scopus 로고    scopus 로고
    • Essential role of Plzf in maintenance of spermatogonial stem cells
    • Costoya, J.A. et al. Essential role of Plzf in maintenance of spermatogonial stem cells. Nat. Genet. 36, 653-659 (2004).
    • (2004) Nat. Genet. , vol.36 , pp. 653-659
    • Costoya, J.A.1
  • 7
    • 14544288635 scopus 로고    scopus 로고
    • The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment
    • He, X. et al. The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment. Nature 433, 826-833 (2005).
    • (2005) Nature , vol.433 , pp. 826-833
    • He, X.1
  • 8
    • 0038243177 scopus 로고    scopus 로고
    • Mutations of the BCL6 proto-oncogene disrupt its negative autoregulation in diffuse large B-cell lymphoma
    • Pasqualucci, L. et al. Mutations of the BCL6 proto-oncogene disrupt its negative autoregulation in diffuse large B-cell lymphoma. Blood 101, 2914-2923 (2003).
    • (2003) Blood , vol.101 , pp. 2914-2923
    • Pasqualucci, L.1
  • 9
    • 16844375768 scopus 로고    scopus 로고
    • The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection
    • Sun, G. et al. The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection. Nat. Immunol. 6, 373-381 (2005).
    • (2005) Nat. Immunol. , vol.6 , pp. 373-381
    • Sun, G.1
  • 10
    • 78650278812 scopus 로고    scopus 로고
    • Overexpression of proto-oncogene FBI-1 activates membrane type 1-matrix metalloproteinase in association with adverse outcome in ovarian cancers
    • Jiang, L. et al. Overexpression of proto-oncogene FBI-1 activates membrane type 1-matrix metalloproteinase in association with adverse outcome in ovarian cancers. Mol. Cancer 9, 318 (2010).
    • (2010) Mol. Cancer , vol.9 , pp. 318
    • Jiang, L.1
  • 11
    • 77956444364 scopus 로고    scopus 로고
    • Expression of leukemia/lymphoma-related factor (LRF/POKEMON) in human breast carcinoma and other cancers
    • Aggarwal, A. et al. Expression of leukemia/lymphoma-related factor (LRF/POKEMON) in human breast carcinoma and other cancers. Exp. Mol. Pathol. 89, 140-148 (2010).
    • (2010) Exp. Mol. Pathol. , vol.89 , pp. 140-148
    • Aggarwal, A.1
  • 12
    • 77953206108 scopus 로고    scopus 로고
    • ZBTB7 overexpression contributes to malignancy in breast cancer
    • Qu, H. et al. ZBTB7 overexpression contributes to malignancy in breast cancer. Cancer Invest. 28, 672-678 (2010).
    • (2010) Cancer Invest. , vol.28 , pp. 672-678
    • Qu, H.1
  • 13
    • 77649224375 scopus 로고    scopus 로고
    • Functional identification of LRF as an oncogene that bypasses RASV12-induced senescence via upregulation of CYCLIN e
    • Vredeveld, L.C., Rowland, B.D., Douma, S., Bernards, R. & Peeper, D.S. Functional identification of LRF as an oncogene that bypasses RASV12-induced senescence via upregulation of CYCLIN E. Carcinogenesis 31, 201-207 (2010).
    • (2010) Carcinogenesis , vol.31 , pp. 201-207
    • Vredeveld, L.C.1    Rowland, B.D.2    Douma, S.3    Bernards, R.4    Peeper, D.S.5
  • 14
    • 52149103352 scopus 로고    scopus 로고
    • Overexpression of Pokemon in non-small cell lung cancer and foreshowing tumor biological behavior as well as clinical results
    • Zhao, Z.H. et al. Overexpression of Pokemon in non-small cell lung cancer and foreshowing tumor biological behavior as well as clinical results. Lung Cancer 62, 113-119 (2008).
    • (2008) Lung Cancer , vol.62 , pp. 113-119
    • Zhao, Z.H.1
  • 15
    • 23244460597 scopus 로고    scopus 로고
    • Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
    • Chen, Z. et al. Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature 436, 725-730 (2005).
    • (2005) Nature , vol.436 , pp. 725-730
    • Chen, Z.1
  • 16
    • 0035113825 scopus 로고    scopus 로고
    • Generation of a prostate epithelial cell-specific Cre transgenic mouse model for tissue-specific gene ablation
    • Wu, X. et al. Generation of a prostate epithelial cell-specific Cre transgenic mouse model for tissue-specific gene ablation. Mech. Dev. 101, 61-69 (2001).
    • (2001) Mech. Dev. , vol.101 , pp. 61-69
    • Wu, X.1
  • 17
    • 4243110417 scopus 로고    scopus 로고
    • Pten dose dictates cancer progression in the prostate
    • Trotman, L.C. et al. Pten dose dictates cancer progression in the prostate. PLoS Biol. 1, E59 (2003).
    • (2003) PLoS Biol. , vol.1
    • Trotman, L.C.1
  • 18
    • 77951765345 scopus 로고    scopus 로고
    • Subtle variations in Pten dose determine cancer susceptibility
    • Alimonti, A. et al. Subtle variations in Pten dose determine cancer susceptibility. Nat. Genet. 42, 454-458 (2010).
    • (2010) Nat. Genet. , vol.42 , pp. 454-458
    • Alimonti, A.1
  • 19
    • 79951512852 scopus 로고    scopus 로고
    • SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression
    • Ding, Z. et al. SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression. Nature 470, 269-273 (2011).
    • (2011) Nature , vol.470 , pp. 269-273
    • Ding, Z.1
  • 20
    • 48449092237 scopus 로고    scopus 로고
    • A prostatic intraepithelial neoplasia-dependent p27Kip1 checkpoint induces senescence and inhibits cell proliferation and cancer progression
    • Majumder, P.K. et al. A prostatic intraepithelial neoplasia-dependent p27Kip1 checkpoint induces senescence and inhibits cell proliferation and cancer progression. Cancer Cell 14, 146-155 (2008).
    • (2008) Cancer Cell , vol.14 , pp. 146-155
    • Majumder, P.K.1
  • 21
    • 70350443240 scopus 로고    scopus 로고
    • Differential p53-independent outcomes of p19Arf loss in oncogenesis
    • Chen, Z. et al. Differential p53-independent outcomes of p19Arf loss in oncogenesis. Sci. Signal. 2, ra44 (2009).
    • (2009) Sci. Signal. , vol.2
    • Chen, Z.1
  • 22
    • 33748869724 scopus 로고    scopus 로고
    • Expression of p14ARF, p15INK4b, p16INK4a, and DCR2 increases during prostate cancer progression
    • Zhang, Z., Rosen, D.G., Yao, J.L., Huang, J. & Liu, J. Expression of p14ARF, p15INK4b, p16INK4a, and DCR2 increases during prostate cancer progression. Mod. Pathol. 19, 1339-1343 (2006).
    • (2006) Mod. Pathol. , vol.19 , pp. 1339-1343
    • Zhang, Z.1    Rosen, D.G.2    Yao, J.L.3    Huang, J.4    Liu, J.5
  • 23
    • 0032922670 scopus 로고    scopus 로고
    • Trans-activation of the mouse cartilage-derived retinoic acid-sensitive protein gene by Sox9
    • Xie, W.F., Zhang, X., Sakano, S., Lefebvre, V. & Sandell, L.J. Trans-activation of the mouse cartilage-derived retinoic acid-sensitive protein gene by Sox9. J. Bone Miner. Res. 14, 757-763 (1999).
    • (1999) J. Bone Miner. Res. , vol.14 , pp. 757-763
    • Xie, W.F.1    Zhang, X.2    Sakano, S.3    Lefebvre, V.4    Sandell, L.J.5
  • 24
    • 77951684109 scopus 로고    scopus 로고
    • Aberrant epithelial-mesenchymal Hedgehog signaling characterizes Barrett's metaplasia
    • Wang, D.H. et al. Aberrant epithelial-mesenchymal Hedgehog signaling characterizes Barrett's metaplasia. Gastroenterology 138, 1810-1822 (2010).
    • (2010) Gastroenterology , vol.138 , pp. 1810-1822
    • Wang, D.H.1
  • 25
    • 77955283528 scopus 로고    scopus 로고
    • Type II collagen expression is regulated by tissue-specific miR-675 in human articular chondrocytes
    • Dudek, K.A., Lafont, J.E., Martinez-Sanchez, A. & Murphy, C.L. Type II collagen expression is regulated by tissue-specific miR-675 in human articular chondrocytes. J. Biol. Chem. 285, 24381-24387 (2010).
    • (2010) J. Biol. Chem. , vol.285 , pp. 24381-24387
    • Dudek, K.A.1    Lafont, J.E.2    Martinez-Sanchez, A.3    Murphy, C.L.4
  • 27
    • 20144370200 scopus 로고    scopus 로고
    • OPOSSUM: Identification of over-represented transcription factor binding sites in co-expressed genes
    • Ho Sui, S.J. et al. oPOSSUM: identification of over-represented transcription factor binding sites in co-expressed genes. Nucleic Acids Res. 33, 3154-3164 (2005).
    • (2005) Nucleic Acids Res. , vol.33 , pp. 3154-3164
    • Ho Sui, S.J.1
  • 28
    • 84883191963 scopus 로고    scopus 로고
    • OPOSSUM-3: Advanced analysis of regulatory motif over-representation across genes or ChIP-Seq datasets
    • Kwon, A.T., Arenillas, D.J., Worsley Hunt, R. & Wasserman, W.W. oPOSSUM-3: advanced analysis of regulatory motif over-representation across genes or ChIP-Seq datasets. G3 (Bethesda) 2, 987-1002 (2012).
    • (2012) G3 (Bethesda) , vol.2 , pp. 987-1002
    • Kwon, A.T.1    Arenillas, D.J.2    Worsley Hunt, R.3    Wasserman, W.W.4
  • 29
    • 0038054341 scopus 로고    scopus 로고
    • PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
    • Mootha, V.K. et al. PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat. Genet. 34, 267-273 (2003).
    • (2003) Nat. Genet. , vol.34 , pp. 267-273
    • Mootha, V.K.1
  • 30
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
    • Subramanian, A. et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc. Natl. Acad. Sci. USA 102, 15545-15550 (2005).
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 15545-15550
    • Subramanian, A.1
  • 31
    • 76249098305 scopus 로고    scopus 로고
    • SOX9 elevation in the prostate promotes proliferation and cooperates with PTEN loss to drive tumor formation
    • Thomsen, M.K. et al. SOX9 elevation in the prostate promotes proliferation and cooperates with PTEN loss to drive tumor formation. Cancer Res. 70, 979-987 (2010).
    • (2010) Cancer Res. , vol.70 , pp. 979-987
    • Thomsen, M.K.1
  • 32
    • 40949145618 scopus 로고    scopus 로고
    • SOX9 is expressed in human fetal prostate epithelium and enhances prostate cancer invasion
    • Wang, H. et al. SOX9 is expressed in human fetal prostate epithelium and enhances prostate cancer invasion. Cancer Res. 68, 1625-1630 (2008).
    • (2008) Cancer Res. , vol.68 , pp. 1625-1630
    • Wang, H.1
  • 33
    • 0033974686 scopus 로고    scopus 로고
    • Up-regulation of the chondrogenic Sox9 gene by fibroblast growth factors is mediated by the mitogen-activated protein kinase pathway
    • Murakami, S., Kan, M., McKeehan, W.L. & de Crombrugghe, B. Up-regulation of the chondrogenic Sox9 gene by fibroblast growth factors is mediated by the mitogen-activated protein kinase pathway. Proc. Natl. Acad. Sci. USA 97, 1113-1118 (2000).
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 1113-1118
    • Murakami, S.1    Kan, M.2    McKeehan, W.L.3    De Crombrugghe, B.4
  • 34
    • 84856236340 scopus 로고    scopus 로고
    • Deleted in malignant brain tumors 1 is present in the vascular extracellular matrix and promotes angiogenesis
    • Müller, H. et al. Deleted in malignant brain tumors 1 is present in the vascular extracellular matrix and promotes angiogenesis. Arterioscler. Thromb. Vasc. Biol. 32, 442-448 (2012).
    • (2012) Arterioscler. Thromb. Vasc. Biol. , vol.32 , pp. 442-448
    • Müller, H.1
  • 35
    • 23844549936 scopus 로고    scopus 로고
    • DMBT1 expression and glycosylation during the adenoma-carcinoma sequence in colorectal cancer
    • Robbe, C. et al. DMBT1 expression and glycosylation during the adenoma-carcinoma sequence in colorectal cancer. Biochem. Soc. Trans. 33, 730-732 (2005).
    • (2005) Biochem. Soc. Trans. , vol.33 , pp. 730-732
    • Robbe, C.1
  • 36
    • 22344442480 scopus 로고    scopus 로고
    • Induction of DMBT1 expression by reduced ERK activity during a gastric mucosa differentiation-like process and its association with human gastric cancer
    • Kang, W. et al. Induction of DMBT1 expression by reduced ERK activity during a gastric mucosa differentiation-like process and its association with human gastric cancer. Carcinogenesis 26, 1129-1137 (2005).
    • (2005) Carcinogenesis , vol.26 , pp. 1129-1137
    • Kang, W.1
  • 37
    • 53449083436 scopus 로고    scopus 로고
    • Application of a global proteomic approach to archival precursor lesions: Deleted in malignant brain tumors 1 and tissue transglutaminase 2 are upregulated in pancreatic cancer precursors
    • Cheung, W. et al. Application of a global proteomic approach to archival precursor lesions: deleted in malignant brain tumors 1 and tissue transglutaminase 2 are upregulated in pancreatic cancer precursors. Pancreatology 8, 608-616 (2008).
    • (2008) Pancreatology , vol.8 , pp. 608-616
    • Cheung, W.1
  • 38
    • 14244263015 scopus 로고    scopus 로고
    • The putative tumor suppressor deleted in malignant brain tumors 1 is an estrogen-regulated gene in rodent and primate endometrial epithelium
    • Tynan, S. et al. The putative tumor suppressor deleted in malignant brain tumors 1 is an estrogen-regulated gene in rodent and primate endometrial epithelium. Endocrinology 146, 1066-1073 (2005).
    • (2005) Endocrinology , vol.146 , pp. 1066-1073
    • Tynan, S.1
  • 39
    • 0037430972 scopus 로고    scopus 로고
    • DMBT1, a regulator of mucosal homeostasis through the linking of mucosal defense and regeneration?
    • Kang, W. & Reid, K.B. DMBT1, a regulator of mucosal homeostasis through the linking of mucosal defense and regeneration? FEBS Lett. 540, 21-25 (2003).
    • (2003) FEBS Lett. , vol.540 , pp. 21-25
    • Kang, W.1    Reid, K.B.2
  • 40
    • 68549139989 scopus 로고    scopus 로고
    • Processing of MIA protein during melanoma cell migration
    • Schmidt, J. & Bosserhoff, A.K. Processing of MIA protein during melanoma cell migration. Int. J. Cancer 125, 1587-1594 (2009).
    • (2009) Int. J. Cancer , vol.125 , pp. 1587-1594
    • Schmidt, J.1    Bosserhoff, A.K.2
  • 41
    • 0034897035 scopus 로고    scopus 로고
    • Functional role of melanoma inhibitory activity in regulating invasion and metastasis of malignant melanoma cells in vivo
    • Bosserhoff, A.K., Echtenacher, B., Hein, R. & Buettner, R. Functional role of melanoma inhibitory activity in regulating invasion and metastasis of malignant melanoma cells in vivo. Melanoma Res. 11, 417-421 (2001).
    • (2001) Melanoma Res. , vol.11 , pp. 417-421
    • Bosserhoff, A.K.1    Echtenacher, B.2    Hein, R.3    Buettner, R.4
  • 42
    • 0242413754 scopus 로고    scopus 로고
    • Active detachment involves inhibition of cell-matrix contacts of malignant melanoma cells by secretion of melanoma inhibitory activity
    • Bosserhoff, A.K. et al. Active detachment involves inhibition of cell-matrix contacts of malignant melanoma cells by secretion of melanoma inhibitory activity. Lab. Invest. 83, 1583-1594 (2003).
    • (2003) Lab. Invest. , vol.83 , pp. 1583-1594
    • Bosserhoff, A.K.1
  • 43
    • 0033765663 scopus 로고    scopus 로고
    • Overexpression of melanoma inhibitory activity (MIA) enhances extravasation and metastasis of A-mel 3 melanoma cells in vivo
    • Guba, M. et al. Overexpression of melanoma inhibitory activity (MIA) enhances extravasation and metastasis of A-mel 3 melanoma cells in vivo. Br. J. Cancer 83, 1216-1222 (2000).
    • (2000) Br. J. Cancer , vol.83 , pp. 1216-1222
    • Guba, M.1
  • 44
    • 0034450654 scopus 로고    scopus 로고
    • MIA as a reliable tumor marker in the serum of patients with malignant melanoma
    • Stahlecker, J. et al. MIA as a reliable tumor marker in the serum of patients with malignant melanoma. Anticancer Res. 20, 5041-5044 (2000).
    • (2000) Anticancer Res. , vol.20 , pp. 5041-5044
    • Stahlecker, J.1
  • 45
    • 33847271696 scopus 로고    scopus 로고
    • The imprinted H19 noncoding RNA is a primary microRNA precursor
    • Cai, X. & Cullen, B.R. The imprinted H19 noncoding RNA is a primary microRNA precursor. RNA 13, 313-316 (2007).
    • (2007) RNA , vol.13 , pp. 313-316
    • Cai, X.1    Cullen, B.R.2
  • 46
    • 77950881915 scopus 로고    scopus 로고
    • Oncofetal H19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer
    • Tsang, W.P. et al. Oncofetal H19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer. Carcinogenesis 31, 350-358 (2010).
    • (2010) Carcinogenesis , vol.31 , pp. 350-358
    • Tsang, W.P.1
  • 47
    • 77950486542 scopus 로고    scopus 로고
    • Dissecting the unique role of the retinoblastoma tumor suppressor during cellular senescence
    • Chicas, A. et al. Dissecting the unique role of the retinoblastoma tumor suppressor during cellular senescence. Cancer Cell 17, 376-387 (2010).
    • (2010) Cancer Cell , vol.17 , pp. 376-387
    • Chicas, A.1
  • 48
    • 79551675502 scopus 로고    scopus 로고
    • E2f binding-deficient Rb1 protein suppresses prostate tumor progression in vivo
    • Sun, H. et al. E2f binding-deficient Rb1 protein suppresses prostate tumor progression in vivo. Proc. Natl. Acad. Sci. USA 108, 704-709 (2011).
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 704-709
    • Sun, H.1
  • 49
    • 84879671701 scopus 로고    scopus 로고
    • A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation therapy resistance in prostate cancer
    • published online; doi:10.1038/ng.2650 (2 June)
    • Lunardi, A. et al. A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation therapy resistance in prostate cancer. Nat. Genet. published online; doi:10.1038/ng.2650 (2 June 2013).
    • (2013) Nat. Genet.
    • Lunardi, A.1
  • 50
    • 0036143004 scopus 로고    scopus 로고
    • Gene expression analysis of prostate cancers
    • Luo, J.H. et al. Gene expression analysis of prostate cancers. Mol. Carcinog. 33, 25-35 (2002).
    • (2002) Mol. Carcinog. , vol.33 , pp. 25-35
    • Luo, J.H.1
  • 51
    • 33646256321 scopus 로고    scopus 로고
    • Sex-determining region y box 4 is a transforming oncogene in human prostate cancer cells
    • Liu, P. et al. Sex-determining region Y box 4 is a transforming oncogene in human prostate cancer cells. Cancer Res. 66, 4011-4019 (2006).
    • (2006) Cancer Res. , vol.66 , pp. 4011-4019
    • Liu, P.1
  • 52
    • 0036682002 scopus 로고    scopus 로고
    • Comprehensive gene expression analysis of prostate cancer reveals distinct transcriptional programs associated with metastatic disease
    • LaTulippe, E. et al. Comprehensive gene expression analysis of prostate cancer reveals distinct transcriptional programs associated with metastatic disease. Cancer Res. 62, 4499-4506 (2002).
    • (2002) Cancer Res. , vol.62 , pp. 4499-4506
    • Latulippe, E.1
  • 53
    • 77954255681 scopus 로고    scopus 로고
    • Integrative genomic profiling of human prostate cancer
    • Taylor, B.S. et al. Integrative genomic profiling of human prostate cancer. Cancer Cell 18, 11-22 (2010).
    • (2010) Cancer Cell , vol.18 , pp. 11-22
    • Taylor, B.S.1
  • 54
    • 84863723010 scopus 로고    scopus 로고
    • The mutational landscape of lethal castration-resistant prostate cancer
    • Grasso, C.S. et al. The mutational landscape of lethal castration-resistant prostate cancer. Nature 487, 239-243 (2012).
    • (2012) Nature , vol.487 , pp. 239-243
    • Grasso, C.S.1
  • 55
    • 22244447065 scopus 로고    scopus 로고
    • Integration of gene expression profiling and clinical variables to predict prostate carcinoma recurrence after radical prostatectomy
    • Stephenson, A.J. et al. Integration of gene expression profiling and clinical variables to predict prostate carcinoma recurrence after radical prostatectomy. Cancer 104, 290-298 (2005).
    • (2005) Cancer , vol.104 , pp. 290-298
    • Stephenson, A.J.1
  • 56
    • 9144251970 scopus 로고    scopus 로고
    • Gene expression profiling identifies clinically relevant subtypes of prostate cancer
    • Lapointe, J. et al. Gene expression profiling identifies clinically relevant subtypes of prostate cancer. Proc. Natl. Acad. Sci. USA 101, 811-816 (2004).
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 811-816
    • Lapointe, J.1
  • 57
    • 0043244946 scopus 로고    scopus 로고
    • Transcriptional silencing of zinc finger protein 185 identified by expression profiling is associated with prostate cancer progression
    • Vanaja, D.K., Cheville, J.C., Iturria, S.J. & Young, C.Y. Transcriptional silencing of zinc finger protein 185 identified by expression profiling is associated with prostate cancer progression. Cancer Res. 63, 3877-3882 (2003).
    • (2003) Cancer Res. , vol.63 , pp. 3877-3882
    • Vanaja, D.K.1    Cheville, J.C.2    Iturria, S.J.3    Young, C.Y.4
  • 58
    • 70349448674 scopus 로고    scopus 로고
    • Identification of the transcription factor single-minded homologue 2 as a potential biomarker and immunotherapy target in prostate cancer
    • Arredouani, M.S. et al. Identification of the transcription factor single-minded homologue 2 as a potential biomarker and immunotherapy target in prostate cancer. Clin. Cancer Res. 15, 5794-5802 (2009).
    • (2009) Clin. Cancer Res. , vol.15 , pp. 5794-5802
    • Arredouani, M.S.1
  • 59
    • 33845884027 scopus 로고    scopus 로고
    • Integrative molecular concept modeling of prostate cancer progression
    • Tomlins, S.A. et al. Integrative molecular concept modeling of prostate cancer progression. Nat. Genet. 39, 41-51 (2007).
    • (2007) Nat. Genet. , vol.39 , pp. 41-51
    • Tomlins, S.A.1
  • 60
    • 38849190111 scopus 로고    scopus 로고
    • Tumor immunobiological differences in prostate cancer between African-American and European-American men
    • Wallace, T.A. et al. Tumor immunobiological differences in prostate cancer between African-American and European-American men. Cancer Res. 68, 927-936 (2008).
    • (2008) Cancer Res. , vol.68 , pp. 927-936
    • Wallace, T.A.1
  • 61
    • 49749136970 scopus 로고    scopus 로고
    • The proto-oncogene LRF is under post-transcriptional control of MiR-20a: Implications for senescence
    • Poliseno, L. et al. The proto-oncogene LRF is under post-transcriptional control of MiR-20a: implications for senescence. PLoS ONE 3, e2542 (2008).
    • (2008) PLoS ONE , vol.3
    • Poliseno, L.1
  • 62
    • 77953948708 scopus 로고    scopus 로고
    • Identification of the miR-106b~25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation
    • Poliseno, L. et al. Identification of the miR-106b~25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation. Sci. Signal. 3, ra29 (2010).
    • (2010) Sci. Signal. , vol.3
    • Poliseno, L.1
  • 63
    • 33244474190 scopus 로고    scopus 로고
    • MCM7 amplification and overexpression are associated with prostate cancer progression
    • Ren, B. et al. MCM7 amplification and overexpression are associated with prostate cancer progression. Oncogene 25, 1090-1098 (2006).
    • (2006) Oncogene , vol.25 , pp. 1090-1098
    • Ren, B.1
  • 64
    • 0031945518 scopus 로고    scopus 로고
    • Negative regulation of DNA replication by the retinoblastoma protein is mediated by its association with MCM7
    • Sterner, J.M., Dew-Knight, S., Musahl, C., Kornbluth, S. & Horowitz, J.M. Negative regulation of DNA replication by the retinoblastoma protein is mediated by its association with MCM7. Mol. Cell Biol. 18, 2748-2757 (1998).
    • (1998) Mol. Cell Biol. , vol.18 , pp. 2748-2757
    • Sterner, J.M.1    Dew-Knight, S.2    Musahl, C.3    Kornbluth, S.4    Horowitz, J.M.5
  • 65
    • 27344451557 scopus 로고    scopus 로고
    • Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
    • Tomlins, S.A. et al. Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science 310, 644-648 (2005).
    • (2005) Science , vol.310 , pp. 644-648
    • Tomlins, S.A.1
  • 66
    • 70350109641 scopus 로고    scopus 로고
    • ETS gene fusions in prostate cancer
    • Clark, J.P. & Cooper, C.S. ETS gene fusions in prostate cancer. Nat. Rev. Urol. 6, 429-439 (2009).
    • (2009) Nat. Rev. Urol. , vol.6 , pp. 429-439
    • Clark, J.P.1    Cooper, C.S.2
  • 67
    • 67649425225 scopus 로고    scopus 로고
    • ETS gene fusions in prostate cancer: From discovery to daily clinical practice
    • Tomlins, S.A. et al. ETS gene fusions in prostate cancer: from discovery to daily clinical practice. Eur. Urol. 56, 275-286 (2009).
    • (2009) Eur. Urol. , vol.56 , pp. 275-286
    • Tomlins, S.A.1
  • 68
    • 0032876470 scopus 로고    scopus 로고
    • P53 mutations in prostate cancer bone metastases suggest that selected p53 mutants in the primary site define foci with metastatic potential
    • Navone, N.M. et al. p53 mutations in prostate cancer bone metastases suggest that selected p53 mutants in the primary site define foci with metastatic potential. J. Urol. 161, 304-308 (1999).
    • (1999) J. Urol. , vol.161 , pp. 304-308
    • Navone, N.M.1
  • 69
    • 0036141621 scopus 로고    scopus 로고
    • Loss of p53 and c-myc overrepresentation in stage T2-3N1-3M0 prostate cancer are potential markers for cancer progression
    • Qian, J. et al. Loss of p53 and c-myc overrepresentation in stage T2-3N1-3M0 prostate cancer are potential markers for cancer progression. Mod. Pathol. 15, 35-44 (2002).
    • (2002) Mod. Pathol. , vol.15 , pp. 35-44
    • Qian, J.1
  • 70
    • 66749188650 scopus 로고    scopus 로고
    • Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate
    • Carver, B.S. et al. Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate. Nat. Genet. 41, 619-624 (2009).
    • (2009) Nat. Genet. , vol.41 , pp. 619-624
    • Carver, B.S.1
  • 71
    • 66749100105 scopus 로고    scopus 로고
    • Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis
    • King, J.C. et al. Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis. Nat. Genet. 41, 524-526 (2009).
    • (2009) Nat. Genet. , vol.41 , pp. 524-526
    • King, J.C.1
  • 72
    • 0031796252 scopus 로고    scopus 로고
    • Direct interaction of SRY-related protein SOX9 and steroidogenic factor 1 regulates transcription of the human anti-Mullerian hormone gene
    • De Santa Barbara, P. et al. Direct interaction of SRY-related protein SOX9 and steroidogenic factor 1 regulates transcription of the human anti-Mullerian hormone gene. Mol. Cell Biol. 18, 6653-6665 (1998).
    • (1998) Mol. Cell Biol. , vol.18 , pp. 6653-6665
    • De Santa Barbara, P.1
  • 73
    • 33747794587 scopus 로고    scopus 로고
    • Genome-scale loss-of-function screening with a lentiviral RNAi library
    • Root, D.E., Hacohen, N., Hahn, W.C., Lander, E.S. & Sabatini, D.M. Genome-scale loss-of-function screening with a lentiviral RNAi library. Nat. Methods 3, 715-719 (2006).
    • (2006) Nat. Methods , vol.3 , pp. 715-719
    • Root, D.E.1    Hacohen, N.2    Hahn, W.C.3    Lander, E.S.4    Sabatini, D.M.5
  • 74
    • 70350061670 scopus 로고    scopus 로고
    • LRF is an essential downstream target of GATA1 in erythroid development and regulates BIM-dependent apoptosis
    • Maeda, T. et al. LRF is an essential downstream target of GATA1 in erythroid development and regulates BIM-dependent apoptosis. Dev. Cell 17, 527-540 (2009).
    • (2009) Dev. Cell , vol.17 , pp. 527-540
    • Maeda, T.1
  • 75
    • 0036173289 scopus 로고    scopus 로고
    • Quantitative HOX expression in chromosomally defined subsets of acute myelogenous leukemia
    • Drabkin, H.A. et al. Quantitative HOX expression in chromosomally defined subsets of acute myelogenous leukemia. Leukemia 16, 186-195 (2002).
    • (2002) Leukemia , vol.16 , pp. 186-195
    • Drabkin, H.A.1


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