-
1
-
-
0034890863
-
Hematologic malignancies
-
Gilliland DG (2001) Hematologic malignancies. Curr Opin Hematol 8: 189-191.
-
(2001)
Curr Opin Hematol
, vol.8
, pp. 189-191
-
-
Gilliland, D.G.1
-
2
-
-
27244452986
-
Genetics of myeloid malignancies: Pathogenetic and clinical implications
-
Frohling S, Scholl C, Gilliland DG, Levine RL (2005) Genetics of myeloid malignancies: pathogenetic and clinical implications. J Clin Oncol 23: 6285-6295.
-
(2005)
J Clin Oncol
, vol.23
, pp. 6285-6295
-
-
Frohling, S.1
Scholl, C.2
Gilliland, D.G.3
Levine, R.L.4
-
3
-
-
18544364773
-
Cancer epigenetics and methylation
-
discussion 1807-1808
-
Esteller M, Fraga MF, Paz MF, Campo E, Colomer D, et al. (2002) Cancer epigenetics and methylation. Science 297: 1807-1808; discussion 1807-1808.
-
(2002)
Science
, vol.297
, pp. 1807-1808
-
-
Esteller, M.1
Fraga, M.F.2
Paz, M.F.3
Campo, E.4
Colomer, D.5
-
4
-
-
33847065486
-
The epigenomics of cancer
-
Jones PA, Baylin SB (2007) The epigenomics of cancer. Cell 128: 683-692.
-
(2007)
Cell
, vol.128
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
5
-
-
30844462355
-
The fundamental role of epigenetics in hematopoietic malignancies
-
Galm O, Herman JG, Baylin SB (2006) The fundamental role of epigenetics in hematopoietic malignancies. Blood Rev 20: 1-13.
-
(2006)
Blood Rev
, vol.20
, pp. 1-13
-
-
Galm, O.1
Herman, J.G.2
Baylin, S.B.3
-
6
-
-
0035353188
-
Methylation profiling in acute myeloid leukemia
-
Toyota M, Kopecky KJ, Toyota MO, Jair KW, Willman CL, et al. (2001) Methylation profiling in acute myeloid leukemia. Blood 97: 2823-2829.
-
(2001)
Blood
, vol.97
, pp. 2823-2829
-
-
Toyota, M.1
Kopecky, K.J.2
Toyota, M.O.3
Jair, K.W.4
Willman, C.L.5
-
7
-
-
51649122312
-
Aberrant CpG island methylation in acute myeloid leukemia is accentuated at relapse
-
Kroeger H, Jelinek J, Estecio MR, He R, Kondo K, et al. (2008) Aberrant CpG island methylation in acute myeloid leukemia is accentuated at relapse. Blood 112: 1366-1373.
-
(2008)
Blood
, vol.112
, pp. 1366-1373
-
-
Kroeger, H.1
Jelinek, J.2
Estecio, M.R.3
He, R.4
Kondo, K.5
-
8
-
-
77449157068
-
Quantitative DNA methylation predicts survival in adult acute myeloid leukemia
-
Bullinger L, Ehrich M, Dohner K, Schlenk RF, Dohner H, et al. (2010) Quantitative DNA methylation predicts survival in adult acute myeloid leukemia. Blood 115: 636-642.
-
(2010)
Blood
, vol.115
, pp. 636-642
-
-
Bullinger, L.1
Ehrich, M.2
Dohner, K.3
Schlenk, R.F.4
Dohner, H.5
-
9
-
-
73649110641
-
DNA Methylation Signatures Identify Biologically Distinct Subtypes in Acute Myeloid Leukemia
-
Figueroa ME, Lugthart S, Li Y, Erpelinck-Verschueren C, Deng X, et al. (2010) DNA Methylation Signatures Identify Biologically Distinct Subtypes in Acute Myeloid Leukemia. Cancer Cell.
-
(2010)
Cancer Cell
-
-
Figueroa, M.E.1
Lugthart, S.2
Li, Y.3
Erpelinck-Verschueren, C.4
Deng, X.5
-
10
-
-
77449149371
-
DNA methylation predicts survival and response to therapy in patients with myelodysplastic syndromes
-
Shen L, Kantarjian H, Guo Y, Lin E, Shan J, et al. (2010) DNA methylation predicts survival and response to therapy in patients with myelodysplastic syndromes. J Clin Oncol 28: 605-613.
-
(2010)
J Clin Oncol
, vol.28
, pp. 605-613
-
-
Shen, L.1
Kantarjian, H.2
Guo, Y.3
Lin, E.4
Shan, J.5
-
11
-
-
34249982046
-
Gene silencing by DNA methylation in haematological malignancies
-
Boultwood J, Wainscoat JS (2007) Gene silencing by DNA methylation in haematological malignancies. Br J Haematol 138: 3-11.
-
(2007)
Br J Haematol
, vol.138
, pp. 3-11
-
-
Boultwood, J.1
Wainscoat, J.S.2
-
12
-
-
19944431714
-
Differences in anti-apoptotic and multidrug resistance phenotypes in elderly and young acute myeloid leukemia patients are related to the maturation of blast cells
-
Suarez L, Vidriales MB, Moreno MJ, Lopez A, Garcia-Larana J, et al. (2005) Differences in anti-apoptotic and multidrug resistance phenotypes in elderly and young acute myeloid leukemia patients are related to the maturation of blast cells. Haematologica 90: 54-59.
-
(2005)
Haematologica
, vol.90
, pp. 54-59
-
-
Suarez, L.1
Vidriales, M.B.2
Moreno, M.J.3
Lopez, A.4
Garcia-Larana, J.5
-
13
-
-
44449151168
-
Microenvironment determines lineage fate in a human model of MLL-AF9 leukemia
-
Wei J, Wunderlich M, Fox C, Alvarez S, Cigudosa JC, et al. (2008) Microenvironment determines lineage fate in a human model of MLL-AF9 leukemia. Cancer Cell 13: 483-495.
-
(2008)
Cancer Cell
, vol.13
, pp. 483-495
-
-
Wei, J.1
Wunderlich, M.2
Fox, C.3
Alvarez, S.4
Cigudosa, J.C.5
-
14
-
-
33644649616
-
High throughput DNA methylation profiling using universal bead arrays
-
Bibikova M, Lin Z, Zhou L, Chudin E, Garcia EW, et al. (2006) High throughput DNA methylation profiling using universal bead arrays. Genome Res 16: 383-393.
-
(2006)
Genome Res
, vol.16
, pp. 383-393
-
-
Bibikova, M.1
Lin, Z.2
Zhou, L.3
Chudin, E.4
Garcia, E.W.5
-
15
-
-
2442667212
-
Highly parallel SNP genotyping
-
Fan JB, Oliphant A, Shen R, Kermani BG, Garcia F, et al. (2003) Highly parallel SNP genotyping. Cold Spring Harb Symp Quant Biol 68: 69-78.
-
(2003)
Cold Spring Harb Symp Quant Biol
, vol.68
, pp. 69-78
-
-
Fan, J.B.1
Oliphant, A.2
Shen, R.3
Kermani, B.G.4
Garcia, F.5
-
16
-
-
64049094683
-
New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling
-
Martin-Subero JI, Kreuz M, Bibikova M, Bentink S, Ammerpohl O, et al. (2009) New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling. Blood 113: 2488-2497.
-
(2009)
Blood
, vol.113
, pp. 2488-2497
-
-
Martin-Subero, J.I.1
Kreuz, M.2
Bibikova, M.3
Bentink, S.4
Ammerpohl, O.5
-
17
-
-
70349185569
-
A comprehensive microarray-based DNA methylation study of 367 hematological neoplasms
-
Martin-Subero JI, Ammerpohl O, Bibikova M, Wickham-Garcia E, Agirre X, et al. (2009) A comprehensive microarray-based DNA methylation study of 367 hematological neoplasms. PLoS ONE 4: e6986.
-
(2009)
PLoS ONE
, vol.4
-
-
Martin-Subero, J.I.1
Ammerpohl, O.2
Bibikova, M.3
Wickham-Garcia, E.4
Agirre, X.5
-
18
-
-
0037133565
-
Comprehensive analysis of CpG islands in human chromosomes 21 and 22
-
Takai D, Jones PA (2002) Comprehensive analysis of CpG islands in human chromosomes 21 and 22. Proc Natl Acad Sci USA 99: 3740-3745.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 3740-3745
-
-
Takai, D.1
Jones, P.A.2
-
19
-
-
33745130696
-
Downregulation of DBC1 expression in acute lymphoblastic leukaemia is mediated by aberrant methylation of its promoter
-
San Jose-Eneriz E, Agirre X, Roman-Gomez J, Cordeu L, Garate L, et al. (2006) Downregulation of DBC1 expression in acute lymphoblastic leukaemia is mediated by aberrant methylation of its promoter. Br J Haematol 134: 137-144.
-
(2006)
Br J Haematol
, vol.134
, pp. 137-144
-
-
San Jose-Eneriz, E.1
Agirre, X.2
Roman-Gomez, J.3
Cordeu, L.4
Garate, L.5
-
20
-
-
23044514669
-
Epigenetic differences arise during the lifetime of monozygotic twins
-
Fraga MF, Ballestar E, Paz MF, Ropero S, Setien F, et al. (2005) Epigenetic differences arise during the lifetime of monozygotic twins. Proc Natl Acad Sci USA 102: 10604-10609.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 10604-10609
-
-
Fraga, M.F.1
Ballestar, E.2
Paz, M.F.3
Ropero, S.4
Setien, F.5
-
21
-
-
40549140112
-
SignS: A parallelized, open-source, freely available, web based tool for gene selection and molecular signatures for survival and censored data
-
Diaz-Uriarte R (2008) SignS: a parallelized, open-source, freely available, web based tool for gene selection and molecular signatures for survival and censored data. BMC Bioinformatics 9: 30.
-
(2008)
BMC Bioinformatics
, vol.9
, pp. 30
-
-
Diaz-Uriarte, R.1
-
22
-
-
44949231424
-
Analyzing real-time PCR data by the comparative C(T) method
-
Schmittgen TD, Livak KJ (2008) Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc 3: 1101-1108.
-
(2008)
Nat Protoc
, vol.3
, pp. 1101-1108
-
-
Schmittgen, T.D.1
Livak, K.J.2
-
23
-
-
77957904102
-
Epigenetic Regulation of Non-Canonical Wnt Pathway in Acute Myeloid Leukemia
-
Martin V, Valencia A, Agirre X, Cervera J, Jose-Eneriz ES, et al. (2009) Epigenetic Regulation of Non-Canonical Wnt Pathway in Acute Myeloid Leukemia. Cancer Sci.
-
(2009)
Cancer Sci
-
-
Martin, V.1
Valencia, A.2
Agirre, X.3
Cervera, J.4
Jose-Eneriz, E.S.5
-
24
-
-
70349311852
-
Wnt signaling pathway is epigenetically regulated by methylation of Wnt antagonists in acute myeloid leukemia
-
Valencia A, Roman-Gomez J, Cervera J, Such E, Barragan E, et al. (2009) Wnt signaling pathway is epigenetically regulated by methylation of Wnt antagonists in acute myeloid leukemia. Leukemia 23: 1658-1666.
-
(2009)
Leukemia
, vol.23
, pp. 1658-1666
-
-
Valencia, A.1
Roman-Gomez, J.2
Cervera, J.3
Such, E.4
Barragan, E.5
-
25
-
-
34848812553
-
CpG island methylation in a mouse model of lymphoma is driven by the genetic configuration of tumor cells
-
Opavsky R, Wang SH, Trikha P, Raval A, Huang Y, et al. (2007) CpG island methylation in a mouse model of lymphoma is driven by the genetic configuration of tumor cells. PLoS Genet 3: 1757-1769.
-
(2007)
PLoS Genet
, vol.3
, pp. 1757-1769
-
-
Opavsky, R.1
Wang, S.H.2
Trikha, P.3
Raval, A.4
Huang, Y.5
-
26
-
-
59149104026
-
Consistent deregulation of gene expression between human and murine MLL rearrangement leukemias
-
Li Z, Luo RT, Mi S, Sun M, Chen P, et al. (2009) Consistent deregulation of gene expression between human and murine MLL rearrangement leukemias. Cancer Res 69: 1109-1116.
-
(2009)
Cancer Res
, vol.69
, pp. 1109-1116
-
-
Li, Z.1
Luo, R.T.2
Mi, S.3
Sun, M.4
Chen, P.5
-
27
-
-
33751071630
-
The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages
-
Iwasaki H, Mizuno S, Arinobu Y, Ozawa H, Mori Y, et al. (2006) The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages. Genes Dev 20: 3010-3021.
-
(2006)
Genes Dev
, vol.20
, pp. 3010-3021
-
-
Iwasaki, H.1
Mizuno, S.2
Arinobu, Y.3
Ozawa, H.4
Mori, Y.5
-
28
-
-
2542455620
-
Stepwise reprogramming of B cells into macrophages
-
Xie H, Ye M, Feng R, Graf T (2004) Stepwise reprogramming of B cells into macrophages. Cell 117: 663-676.
-
(2004)
Cell
, vol.117
, pp. 663-676
-
-
Xie, H.1
Ye, M.2
Feng, R.3
Graf, T.4
-
29
-
-
0036095217
-
The AML1-ETO fusion protein promotes the expansion of human hematopoietic stem cells
-
Mulloy JC, Cammenga J, MacKenzie KL, Berguido FJ, Moore MA, et al. (2002) The AML1-ETO fusion protein promotes the expansion of human hematopoietic stem cells. Blood 99: 15-23.
-
(2002)
Blood
, vol.99
, pp. 15-23
-
-
Mulloy, J.C.1
Cammenga, J.2
Mackenzie, K.L.3
Berguido, F.J.4
Moore, M.A.5
-
30
-
-
33748176403
-
Human CD34+ cells expressing the inv(16) fusion protein exhibit a myelomonocytic phenotype with greatly enhanced proliferative ability
-
Wunderlich M, Krejci O, Wei J, Mulloy JC (2006) Human CD34+ cells expressing the inv(16) fusion protein exhibit a myelomonocytic phenotype with greatly enhanced proliferative ability. Blood 108: 1690-1697.
-
(2006)
Blood
, vol.108
, pp. 1690-1697
-
-
Wunderlich, M.1
Krejci, O.2
Wei, J.3
Mulloy, J.C.4
-
31
-
-
46749094288
-
Concurrent methylation of promoters from tumor associated genes predicts outcome in acute myeloid leukemia
-
Hess CJ, Errami A, Berkhof J, Denkers F, Ossenkoppele GJ, et al. (2008) Concurrent methylation of promoters from tumor associated genes predicts outcome in acute myeloid leukemia. Leuk Lymphoma 49: 1132-1141.
-
(2008)
Leuk Lymphoma
, vol.49
, pp. 1132-1141
-
-
Hess, C.J.1
Errami, A.2
Berkhof, J.3
Denkers, F.4
Ossenkoppele, G.J.5
-
32
-
-
0035942497
-
Negative regulation of G(1)/S transition by the candidate bladder tumour suppressor gene DBCCR1
-
Nishiyama H, Gill JH, Pitt E, Kennedy W, Knowles MA (2001) Negative regulation of G(1)/S transition by the candidate bladder tumour suppressor gene DBCCR1. Oncogene 20: 2956-2964.
-
(2001)
Oncogene
, vol.20
, pp. 2956-2964
-
-
Nishiyama, H.1
Gill, J.H.2
Pitt, E.3
Kennedy, W.4
Knowles, M.A.5
-
33
-
-
41949106988
-
P15Ink4b: Dual function in myelopoiesis and inactivation in myeloid disease
-
Rosu-Myles M, Wolff L (2008) p15Ink4b: dual function in myelopoiesis and inactivation in myeloid disease. Blood Cells Mol Dis 40: 406-409.
-
(2008)
Blood Cells Mol Dis
, vol.40
, pp. 406-409
-
-
Rosu-Myles, M.1
Wolff, L.2
-
34
-
-
0034654269
-
Aberrant p15 promoter methylation in adult and childhood acute leukemias of nearly all morphologic subtypes: Potential prognostic implications
-
Wong IH, Ng MH, Huang DP, Lee JC (2000) Aberrant p15 promoter methylation in adult and childhood acute leukemias of nearly all morphologic subtypes: potential prognostic implications. Blood 95: 1942-1949.
-
(2000)
Blood
, vol.95
, pp. 1942-1949
-
-
Wong, I.H.1
Ng, M.H.2
Huang, D.P.3
Lee, J.C.4
-
35
-
-
42549113460
-
Frequent hypermethylation of DBC1 in malignant lymphoproliferative neoplasms
-
Gronbaek K, Ralfkiaer U, Dahl C, Hother C, Burns JS, et al. (2008) Frequent hypermethylation of DBC1 in malignant lymphoproliferative neoplasms. Mod Pathol 21: 632-638.
-
(2008)
Mod Pathol
, vol.21
, pp. 632-638
-
-
Gronbaek, K.1
Ralfkiaer, U.2
Dahl, C.3
Hother, C.4
Burns, J.S.5
-
36
-
-
60849089645
-
Aberrant DNA methylation is a dominant mechanism in MDS progression to AML
-
Jiang Y, Dunbar A, Gondek LP, Mohan S, Rataul M, et al. (2009) Aberrant DNA methylation is a dominant mechanism in MDS progression to AML. Blood 113: 1315-1325.
-
(2009)
Blood
, vol.113
, pp. 1315-1325
-
-
Jiang, Y.1
Dunbar, A.2
Gondek, L.P.3
Mohan, S.4
Rataul, M.5
-
37
-
-
0032520902
-
Structure and methylation-based silencing of a gene (DBCCR1) within a candidate bladder cancer tumor suppressor region at 9q32-q33
-
Habuchi T, Luscombe M, Elder PA, Knowles MA (1998) Structure and methylation-based silencing of a gene (DBCCR1) within a candidate bladder cancer tumor suppressor region at 9q32-q33. Genomics 48: 277-288.
-
(1998)
Genomics
, vol.48
, pp. 277-288
-
-
Habuchi, T.1
Luscombe, M.2
Elder, P.A.3
Knowles, M.A.4
-
38
-
-
17744373486
-
Frequent silencing of DBC1 is by genetic or epigenetic mechanisms in non-small cell lung cancers
-
Izumi H, Inoue J, Yokoi S, Hosoda H, Shibata T, et al. (2005) Frequent silencing of DBC1 is by genetic or epigenetic mechanisms in non-small cell lung cancers. Hum Mol Genet 14: 997-1007.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 997-1007
-
-
Izumi, H.1
Inoue, J.2
Yokoi, S.3
Hosoda, H.4
Shibata, T.5
-
39
-
-
0037114753
-
Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: Results from Cancer and Leukemia Group B (CALGB 8461)
-
Byrd JC, Mrozek K, Dodge RK, Carroll AJ, Edwards CG, et al. (2002) Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461). Blood 100: 4325-4336.
-
(2002)
Blood
, vol.100
, pp. 4325-4336
-
-
Byrd, J.C.1
Mrozek, K.2
Dodge, R.K.3
Carroll, A.J.4
Edwards, C.G.5
|