Nerve injury induces glial cell line-derived neurotrophic factor (GDNF) expression in schwann cells through purinergic signaling and the PKC-PKD pathway

GLIA

Volumn 61, Issue 7, 2013, Pages 1029-1040

  Xu, Pin ^a,b   Rosen, Kenneth M ^a,b   Hedstrom, Kristian ^a,b   Rey, Osvaldo ^c,d   Guha, Sushovan ^e   Hart, Courtney ^a   Corfas, Gabriel ^a,b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d Hospital de Clínicas José de San Martín   (Argentina)

^e UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Apyrase; GDNF; Nerve injury; Protein kinase D; Purinergic receptor; Schwann cell

Indexed keywords

GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; PROTEIN KINASE C; PROTEIN KINASE D; PURINERGIC RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; EX VIVO STUDY; IN VITRO STUDY; IN VIVO STUDY; MALE; NERVE CELL; NEUROPATHY; NONHUMAN; PERIPHERAL NERVE INJURY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SCHWANN CELL; SCIATIC NERVE; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; AXOTOMY; CELLS, CULTURED; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; MALE; PROTEIN KINASE C; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PURINERGIC; RNA, MESSENGER; SCHWANN CELLS; SCIATIC NEUROPATHY; SERINE; SIGNAL TRANSDUCTION; TIME FACTORS; UP-REGULATION;

EID: 84879600891     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.22491     Document Type: Article

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