The short- and long-term effects of Seprafilm® on peripheral nerves: A histological and functional study

Journal of Reconstructive Microsurgery

Volumn 25, Issue 6, 2009, Pages 345-354

  Magill, Christina Kenney ^a   Tuffaha, Sami H ^a   Yee, Andrew ^a   Luciano, Janina P ^a   Hunter, Daniel A ^a   Mackinnon, Susan E ^a   Borschel, Gregory H ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adhesions; Carboxymethycellulose hyaluronate; Peripheral nerve; Scar reduction; Seprafilm

Indexed keywords

BIOMATERIAL; CARBOXYMETHYLCELLULOSE; HYALURONIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FUNCTIONAL ASSESSMENT; MALE; NERVE REGENERATION; NEUROLYSIS; NONHUMAN; OUTCOME ASSESSMENT; PERIPHERAL NERVE INJURY; PRIORITY JOURNAL; RAT; SAFETY; SCAR; SCIATIC NERVE;

ANIMALS; CICATRIX; DISEASE MODELS, ANIMAL; HYALURONIC ACID; MALE; MEMBRANES, ARTIFICIAL; MICROSURGERY; NERVE REGENERATION; PERIPHERAL NERVOUS SYSTEM DISEASES; RATS; RATS, INBRED LEW; SCIATIC NERVE; TISSUE ADHESIONS;

EID: 70049093180     PISSN: 0743684X     EISSN: 10988947     Source Type: Journal    
DOI: 10.1055/s-0029-1215526     Document Type: Article

References (35)

1. Adanali G, Verdi M, Tuncel A, Erdogan B, Kargi E. Effects of hyaluronic acid-carboxymethylcellulose membrane on extraneural adhesion formation and peripheral nerve regeneration. J Reconstr Microsurg 2003;19:29-35 (Pubitemid 36176663)
2. Özgenel GY. Effects of hyaluronic acid on peripheral nerve scarring and regeneration in rats. Microsurgery 2003;23:575-581 (Pubitemid 38049967)
3. Sanders RJ, Hammond SL, Rao NM. Observations on the use of Seprafilm on the brachial plexus in 249 operations for neurogenic thoracic outlet syndrome. Hand 2007;2:179-183
4. Becker JM, Dayton MT, Fazio VW, et al. Prevention of postoperative abdominal adhesions by a sodium hyaluronate-based bioresorbable membrane: a prospective, randomized, double-blind multicenter study. J Am Coll Surg 1996;183:297-306 (Pubitemid 126751367)
5. Fazio VW, Cohen Z, Fleshman JW, et al. Reduction in adhesive small-bowel obstruction by Seprafilmadhesion barrier after intestinal resection. Dis Colon Rectum 2006;49:1-11 (Pubitemid 41830649)
6. Klinger PP, Floch N, Seelig M, et al. Seprafilm®-induced peritoneal inflammation: a previously unknown complication: report of a case. Dis Colon Rectum 1999;42:1639-1642 (Pubitemid 30007602)
7. Zeng Q, Yu Z, You J, Zhang Q. Efficacy and safety of Seprafilm for preventing postoperative abdominal adhesion: systematic review and meta-analysis. World J Surg 2007;31:2125-2131 (Pubitemid 47620247)
8. Kayaoglu HA, Ozkan N, Hazinedaroglu SM, Ersoy OF, Koseoglu RD. An assessment of the effects of two types of bioresorbable barriers to prevent postoperative intra-abdominal adhesions in rats. Surg Today 2005;35:946-950 (Pubitemid 41540064)
9. Brenner MJ, Moradzadeh A, Myckatyn TM, et al. Role of timing in assessment of nerve regeneration. Microsurgery 2008;28:265-272 (Pubitemid 351770170)
10. Gundersen HJ, Bagger P, Bendtsen TF, et al. The new stereological tools: disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis. APMIS 1988;96:857-881 (Pubitemid 18270672)
11. Hunter DA, Moradzadeh A, Whitlock EL, et al. Binary imaging analysis for comprehensive quantitative histomorphometry of peripheral nerve. J Neurosci Methods 2007;166:116-124 (Pubitemid 47374805)
12. Brown CJ, Mackinnon SE, Evans PJ, et al. Self-evaluation of walking-track measurement using a Sciatic Function Index. Microsurgery 1989;10:226-235
13. Sunderland S, Bradley KC. Endoneurial tube shrinkage in the distal segment of a severed nerve. J Comp Neurol 1950;93:411-420
14. Atkins S, Smith KG, Loescher AR, Boissonade FM, O'Kane S, Ferguson MW, Robinson PP. Scarring impedes regeneration at sites of peripheral nerve repair. Neuroreport 2006;17:1245-1249 (Pubitemid 44337060)
15. Nachemson AK, Lundborg G, Myrhage R, Rank F. Nerve regeneration after pharmacological suppression of the scar reaction at the suture site. An experimental study on the effect of estrogen-progesterone, methylprednisolone- acetate and cis-hydroxyproline in rat sciatic nerve. Scand J Plast Reconstr Surg 1985;19:255-260 (Pubitemid 16213124)
16. Wehling P, Pak M, Cleveland S, Nieper R. The influence of bacterial collagenase on regeneration of severed rat sciatic nerves. Acta Neurochir (Wien) 1992;119:121-127 (Pubitemid 23022781)
17. Nath RK, Kwon B, Mackinnon SE, Jensen JN, Reznik S, Boutros S. Antibody to transforming growth factor beta reduces collagen production in injured peripheral nerve. Plast Reconstr Surg 1998;102:1100-1106 (Pubitemid 128723396)
18. Davison SP, McCaffrey TV, Porter MN, Manders E. Improved nerve regeneration with neutralisation of transforming growth factor-beta 1. Laryngoscope 1999;109:631-635 (Pubitemid 29165917)
19. Rydevik M, Bergström F, Mitts C, Danielsen N. Locally-applied collagenase and regeneration of transsected and repaired rat sciatic nerves. Scand J Plast Reconstr Surg Hand Surg 2002;36:193-196 (Pubitemid 35177876)
20. Ozay R, Bekar A, Kocaeli H, Karli N, Filiz G, Ulus IH. Citicoline improves functional recovery, promotes nerve regeneration, and reduces postoperative scarring after peripheral nerve surgery in rats. Surg Neurol 2007;68:615-622 (Pubitemid 350160838)
21. Atkins S, Smith KG, Loescher AR, Boissonade FM, Ferguson MW, Robinson PP. The effect of antibodies to TGF-beta1 and TGF-beta2 at a site of sciatic nerve repair. J Peripher Nerv Syst 2006;11:286-293
22. Wang KK, Nemeth IR, Seckel BR, et al. Hyaluronic acid enhances peripheral nerve regeneration in vivo. Microsurgery 1998;18:270-275
23. Özgenel GY, Fílíz G. Combined application of human amniotic membrane wrapping and hyaluronic acid injection in epineurectomized rat sciatic nerve. J Reconstr Microsurg 2004;20:153-157 (Pubitemid 38264008)
24. Beck DE, Cohen Z, Fleshman JW, et al. A prospective, randomized, multicenter, controlled study of the safety of Seprafilm adhesion barrier in abdominopelvic surgery of the intestine. Dis Colon Rectum 2003;46:1310-1319 (Pubitemid 37267623)
25. Menderes A, Mola F, Tayfur V, Vayvada H, Barutçu A. Prevention of peritendinous adhesions following flexor tendon injury with seprafilm. Ann Plast Surg 2004;53:560-564 (Pubitemid 39565028)
26. Cohen Z, Senagore AJ, Dayton MT, et al. Prevention of postoperative abdominal adhesions by a novel, glycerol/sodium hyaluronate/ carboxymethycellulose-based bioresorbable membrane: a prospective, randomized, evaluator-blinded multicenter study. Dis Colon Rectum 2005;48:1130-1139 (Pubitemid 40897855)
27. Mohri Y, Uchida K, Araki T, et al. Hyaluronic acidcarboxycellulose membrane (Seprafilm) reduces early postoperative small bowel obstruction in gastrointestinal surgery. Am Surg 2005;71:861-863
28. Bristow RE, Santillan A, Diaz-Montes TP, Gardner GJ, Giuntoli RL II, Peeler ST. Prevention of adhesion formation after radical hysterectomy using a sodium hyaluronate-carboxymethylcellulose (HA-CMC) barrier: a cost-effectiveness analysis. Gynecol Oncol 2007;104:739-746 (Pubitemid 46240248)
29. Caylan R, Bektas D. Preservation of the mastoid aeration and prevention of mastoid dimpling in chronic otitis media with cholesteatoma surgery using hyaluronate-based bioresorbable membrane (Seprafilm). Eur Arch Otorhinolaryngol 2007;264:377-380 (Pubitemid 46354900)
30. Konakçi E, Koyuncu M, Unal R, Tekat A, Uyar M. Repair of subtotal tympanic membrane perforations with Seprafilm. J Laryngol Otol 2004;118:862-865 (Pubitemid 39657143)
31. Sanger JR, Kolachalam R, Komorowski RA, Yousif NJ, Matloub HS. Short-term effect of silicone gel on peripheral nerves: a histologic study. Plast Reconstr Surg 1992;89:931-940
32. David M, Sarani B, Moid F, Tabbara S, Orkin BA. Paradoxical inflammatory reaction to Seprafilm: case report and review of the literature. South Med J 2005;98:1039-1041 (Pubitemid 41572211)
33. Klinger PP, Floch N, Seelig M, et al. Seprafilm®-induced peritoneal inflammation: a previously unknown complication: report of a case. Dis Colon Rectum 1999;42:1639-1642 (Pubitemid 30007602)
34. Remzi FH, Oncel M, Church JM, Senagore AJ, Delaney CP, Fazio VW. An unusual complication after hyaluronate-based bioresorbable membrane (Seprafilm) application. Am Surg 2003;69:356-357
35. Best TJ, Mackinnon SE, Midha R, Hunter DA, Evans PJ. Revascularization of peripheral nerve autografts and allografts. Plast Reconstr Surg 1999;104:152-160 (Pubitemid 29283204)