Glial cell line-derived neurotrophic factor enhances axonal regeneration following sciatic nerve transection in adult rats

Brain Research

Volumn 902, Issue 2, 2001, Pages 272-276

  Chen, Zhe Yu ^a   Chai, Yan Feng ^a   Cao, Li ^a   Lu, Chang Lin ^a   He, Cheng ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Axonal regeneration; GAP 43; GDNF; Sciatic nerve

Indexed keywords

COLLAGEN GEL; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; HORSERADISH PEROXIDASE; NEUROMODULIN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CONVALESCENCE; GLIA CELL; MALE; MYELINATED NERVE; NERVE FIBER; NERVE FIBER TRANSECTION; NERVE REGENERATION; NERVE TRANSECTION; NEUROPATHY; NONHUMAN; PERIPHERAL NERVE INJURY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SCIATIC NERVE; SPINAL CORD MOTONEURON;

ANIMALS; AXONS; CELL SURVIVAL; COLLAGEN; GAP-43 PROTEIN; GELS; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; HORSERADISH PEROXIDASE; IMMUNOHISTOCHEMISTRY; MALE; MOTOR NEURONS; NERVE CRUSH; NERVE FIBERS, MYELINATED; NERVE GROWTH FACTORS; NERVE REGENERATION; NERVE TISSUE PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RECOVERY OF FUNCTION; SCIATIC NERVE; SPINAL CORD;

EID: 0035369277     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(01)02395-2     Document Type: Article

References (20)

1. Permanent rescue of lesioned neonatal motoneurons and enhanced axonal regeneration by adenovirus-mediated expression of glial cell-line-derived neurotrophic factor
2. Human glial cell line-derived neurotrophic factor: A structure-function analysis
3. Preparation of recombinant human GDNF by baculovirus expression system and analysis of its biological activities
4. Protective effect of exogenous glial cell line-derived neurotrophic factor on neurons after sciatic nerve injury in rats
5. Glial cell line-derived neurotrophic factor promotes survival and induces differentiation through the phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathway respectively in PC12 cells
6. Spinal cord contusion in the rat: Behavioral analysis of functional neurologic impairment
7. GDNF mRNA in Schwann cells and DRG satellite cells after chronic sciatic nerve injury
8. A quick and accurate line-sampling technique to quantify myelinated axons in peripheral nerve cross-sections
9. GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF
10. Elevated synthesis of an axonally transported protein correlates with axon outgrowth in normal and injured pyramidal tracts
11. GDNF: A glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons
12. Tetramethyl benzidine for horseradish peroxidase neurohistochemistry: A non-carcinogenic blue reaction product with superior sensitivity for visualizing neural afferents and efferents
13. Differential regulation of mRNAs for GDNF and its receptors Ret and GDNFR alpha after sciatic nerve lesion in the mouse
14. Receptors of the glial cell line-derived neurotrophic factor family of neurotrophic factors signal cell survival through the phosphatidylinositol 3-kinase pathway in spinal cord motoneurons
15. Axonal transport and localization of B-50/GAP-43-like immunoreactivity in regenerating sciatic and facial nerves of the rat
16. Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo
17. Laser or razor? A novel experimental peripheral nerve repair technique
18. Peripheral expression and biological activities of GDNF, a new neurotrophic factor for avian and mammalian peripheral neurons
19. In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons
20. Glial cell line-derived neurotrophic factor (GDNF) promotes the survival of axotomized retinal ganglion cells in adult rats: Comparison to and combination with brain-derived neurotrophic factor (BDNF)