Lecithin cholesterol acyltransferase null mice are protected from diet-induced obesity and insulin resistance in a gender-specific manner through multiple pathways

Journal of Biological Chemistry

Volumn 286, Issue 20, 2011, Pages 17809-17820

  Li, Lixin ^a   Hossain, Mohammad A ^a   Sadat, Sabreena ^a   Hager, Lauren ^a   Liu, Lu ^a   Tam, Laetitia ^a   Schroer, Stephanie ^d   Huogen, Lu ^b,c   Fantus, I George ^b,c   Connelly, Philip W ^a   Woo, Minna ^a,d   Ng, Dominic S ^a  

^a ST MICHAEL'S HOSPITAL   (Canada)

^b MOUNT SINAI HOSPITAL   (Canada)

^c UNIVERSITY HEALTH NETWORK   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOCYTES; ADIPOGENESIS; DIET-INDUCED OBESITY; ENDOPLASMIC RETICULUM STRESS; INSULIN RESISTANCE; INSULIN SENSITIVITY; KNOCK OUTS; LECITHIN-CHOLESTEROL ACYLTRANSFERASE; METABOLIC PHENOTYPE; MRNA LEVEL; MULTIPLE PATHWAYS; SKELETAL MUSCLE; SKELETAL MUSCLE FIBERS; UNFOLDED PROTEIN RESPONSE; WHITE ADIPOSE TISSUES; WNT SIGNALING;

CHOLESTEROL; GENES; INSULIN; METABOLISM; MUSCLE; PHOSPHOLIPIDS; SUGAR (SUCROSE);

NUTRITION;

GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PHOSPHATIDYLCHOLINE STEROL ACYLTRANSFERASE; UNCOUPLING PROTEIN 1; UNCOUPLING PROTEIN 3; WNT PROTEIN;

ADIPOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BROWN ADIPOSE TISSUE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENERGY EXPENDITURE; FEMALE; INSULIN RESISTANCE; LIPID STORAGE; MALE; MARKER GENE; MOUSE; NONHUMAN; OBESITY; PHYSICAL ACTIVITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEX DIFFERENCE; SKELETAL MUSCLE; SUGAR INTAKE; UNFOLDED PROTEIN RESPONSE; UPREGULATION; WHITE ADIPOSE TISSUE;

ADIPOSE TISSUE, WHITE; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; DIET; DIETARY FATS; FEMALE; HEAT-SHOCK PROTEINS; INSULIN RESISTANCE; ION CHANNELS; LECITHIN ACYLTRANSFERASE DEFICIENCY; MALE; MICE; MICE, KNOCKOUT; MITOCHONDRIAL PROTEINS; MUSCLE, SKELETAL; OBESITY; PHOSPHATIDYLCHOLINE-STEROL O-ACYLTRANSFERASE; RECEPTORS, LDL; SEX CHARACTERISTICS; SUCROSE; SWEETENING AGENTS; TRANS-ACTIVATORS; TRANSCRIPTION FACTOR CHOP; UNFOLDED PROTEIN RESPONSE; WNT PROTEINS;

MUS;

EID: 79955947558     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.180893     Document Type: Article

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