메뉴 건너뛰기




Volumn 305, Issue 1, 2013, Pages

Pathogenic and protective role of macrophages in kidney disease

Author keywords

Cell therapy; Kidney disease; Macrophages

Indexed keywords

CYTOKINE; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 4;

EID: 84879591473     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00122.2013     Document Type: Review
Times cited : (66)

References (104)
  • 2
    • 80054728443 scopus 로고    scopus 로고
    • Renal microenvironments and macrophage phenotypes determine progression or resolution of renal inflammation and fibrosis
    • Anders HJ, Ryu M. Renal microenvironments and macrophage phenotypes determine progression or resolution of renal inflammation and fibrosis. Kidney Int 80: 915-925, 2011.
    • (2011) Kidney Int , vol.80 , pp. 915-925
    • Anders, H.J.1    Ryu, M.2
  • 3
    • 0017104730 scopus 로고
    • The macrophagen in human rapidly progressive glomerulonephritis
    • Atkins RC, Holdsworth SR, Glasgow EF, Matthews FE. The macrophagen in human rapidly progressive glomerulonephritis. Lancet 1: 830-832, 1976.
    • (1976) Lancet , vol.1 , pp. 830-832
    • Atkins, R.C.1    Holdsworth, S.R.2    Glasgow, E.F.3    Matthews, F.E.4
  • 6
    • 77952998952 scopus 로고    scopus 로고
    • IL-10/TGFβ-modified macrophages induce regulatory T cells and protect against murine ariamycin nephrosis
    • Cao Q, Wang Y, Zheng D, Sun Y, Wang Y, LeeVW, Alexander SI, Harris DC. IL-10/TGFβ-modified macrophages induce regulatory T cells and protect against murine ariamycin nephrosis. J Am Soc Nephrol 21: 933-942, 2010.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 933-942
    • Cao, Q.1    Wang, Y.2    Zheng, D.3    Sun, Y.4    Wang, Y.5    Lee, V.W.6    Alexander, S.I.7    Harris, D.C.8
  • 7
    • 77956095621 scopus 로고    scopus 로고
    • Macrophages and dendritic cells for treating kidney disease
    • Cao Q, Zheng D, Wang YP, Harris DC. Macrophages and dendritic cells for treating kidney disease. Nephron Exp Nephrol 117: 47-52, 2011.
    • (2011) Nephron Exp Nephrol , vol.117 , pp. 47-52
    • Cao, Q.1    Zheng, D.2    Wang, Y.P.3    Harris, D.C.4
  • 9
    • 59649093518 scopus 로고    scopus 로고
    • Cisplatin primes murine peritoneal macrophages for enhanced expression of nitric oxide, proinflammatory cytokines, TLRs, transcription factors and activation of MAP kinases upon co-incubation with L929 cells
    • Chauhan P, Sodhi A, Shrivastava A. Cisplatin primes murine peritoneal macrophages for enhanced expression of nitric oxide, proinflammatory cytokines, TLRs, transcription factors and activation of MAP kinases upon co-incubation with L929 cells. Immunobiology 214: 197-209, 2009.
    • (2009) Immunobiology , vol.214 , pp. 197-209
    • Chauhan, P.1    Sodhi, A.2    Shrivastava, A.3
  • 10
    • 84859060783 scopus 로고    scopus 로고
    • Rapamycin ameliorates kidney fibrosis by inhibiting the activation of mTOR signaling in interstitial macrophages and myofibroblasts
    • Chen G, Chen H, Wang C, Peng Y, Sun L, Liu H, Liu F. Rapamycin ameliorates kidney fibrosis by inhibiting the activation of mTOR signaling in interstitial macrophages and myofibroblasts. PLos One 7: e33626, 2012.
    • (2012) PLos One , vol.7
    • Chen, G.1    Chen, H.2    Wang, C.3    Peng, Y.4    Sun, L.5    Liu, H.6    Liu, F.7
  • 11
    • 66749135260 scopus 로고    scopus 로고
    • Ccl2/Mcp-1 blockade reduces glomerular and interstitial macrophages but does not ameliorate renal pathology in collagen4A3-deficient mice with autosomal recessive Alport nephropathy
    • Clauss S, Gross O, Kulkarni O, Avila-Ferrufino A, Radomska E, Segerer S, Eulberg D, Klussmann S, Anders HJ. Ccl2/Mcp-1 blockade reduces glomerular and interstitial macrophages but does not ameliorate renal pathology in collagen4A3-deficient mice with autosomal recessive Alport nephropathy. J Pathol 218: 40-47, 2009.
    • (2009) J Pathol , vol.218 , pp. 40-47
    • Clauss, S.1    Gross, O.2    Kulkarni, O.3    Avila-Ferrufino, A.4    Radomska, E.5    Segerer, S.6    Eulberg, D.7    Klussmann, S.8    Anders, H.J.9
  • 13
    • 0032916214 scopus 로고    scopus 로고
    • Macrophage depletion by albumin microencapsulated clodronate: Attenuation of cytokine release in macrophage-dependent glomerulonephritis
    • D'Souza MJ, Oettinger CW, Shah A, Tipping PG, Huang XR, Milton GV. Macrophage depletion by albumin microencapsulated clodronate: attenuation of cytokine release in macrophage-dependent glomerulonephritis. Drug Dev Ind Pharm 25: 591-596, 1999.
    • (1999) Drug Dev Ind Pharm , vol.25 , pp. 591-596
    • D'Souza, M.J.1    Oettinger, C.W.2    Shah, A.3    Tipping, P.G.4    Huang, X.R.5    Milton, G.V.6
  • 14
    • 15044346796 scopus 로고    scopus 로고
    • Renal ischemiareperfusion injury and adenosine 2A receptor-mediated tissue protection: Role of macrophages
    • Day YJ, Huang L, Ye H, Linden J, Okusa MD. Renal ischemiareperfusion injury and adenosine 2A receptor-mediated tissue protection: role of macrophages. Am J Physiol Renal Physiol 288: F722-F731, 2005.
    • (2005) Am J Physiol Renal Physiol , vol.288
    • Day, Y.J.1    Huang, L.2    Ye, H.3    Linden, J.4    Okusa, M.D.5
  • 15
    • 77953881058 scopus 로고    scopus 로고
    • Macrophages and immunologic inflammation of the kidney
    • Duffield JS. Macrophages and immunologic inflammation of the kidney. Semin Nephrol 30: 234-254, 2010.
    • (2010) Semin Nephrol , vol.30 , pp. 234-254
    • Duffield, J.S.1
  • 18
    • 0028931661 scopus 로고
    • Interstitial macrophages as mediators of renal fibrosis
    • Eddy AA. Interstitial macrophages as mediators of renal fibrosis. Exp Nephrol 3: 76-79, 1995.
    • (1995) Exp Nephrol , vol.3 , pp. 76-79
    • Eddy, A.A.1
  • 19
    • 48649109505 scopus 로고    scopus 로고
    • Macrophages and hypoxia in human chronic kidney disease
    • Erwig LP. Macrophages and hypoxia in human chronic kidney disease. Kidney Int 74: 405-406, 2008.
    • (2008) Kidney Int , vol.74 , pp. 405-406
    • Erwig, L.P.1
  • 21
    • 84869017379 scopus 로고    scopus 로고
    • The interferon signature and STAT1 expression in rheumatoid arthritis synovial fluid macrophages are induced by tumor necrosis factor alpha and counter-regulated by the synovial fluid microenvironment
    • Gordon RA, Grigoriev G, Lee A, Kalliolias GD, Ivashkiv LB. The interferon signature and STAT1 expression in rheumatoid arthritis synovial fluid macrophages are induced by tumor necrosis factor alpha and counter-regulated by the synovial fluid microenvironment. Arthritis Rheum 64: 3119-3128, 2012.
    • (2012) Arthritis Rheum , vol.64 , pp. 3119-3128
    • Gordon, R.A.1    Grigoriev, G.2    Lee, A.3    Kalliolias, G.D.4    Ivashkiv, L.B.5
  • 22
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • Gordon S. Alternative activation of macrophages. Nat Rev Immunol 3: 23-35, 2003.
    • (2003) Nat Rev Immunol , vol.3 , pp. 23-35
    • Gordon, S.1
  • 23
    • 28544446111 scopus 로고    scopus 로고
    • Monocyte and macrophage heterogeneity
    • Gordon S, Taylor PR. Monocyte and macrophage heterogeneity. Nat Rev Immunol 5: 953-964, 2005.
    • (2005) Nat Rev Immunol , vol.5 , pp. 953-964
    • Gordon, S.1    Taylor, P.R.2
  • 24
    • 79959758089 scopus 로고    scopus 로고
    • C-fms blockade reverses glomerular macrophage infiltration and halts development of crescentic anti-GBM glomerulonephritis in the rat
    • Han Y, Ma FY, Tesch GH, Manthey CL, Nikolic-Paterson DJ. C-fms blockade reverses glomerular macrophage infiltration and halts development of crescentic anti-GBM glomerulonephritis in the rat. Lab Invest 91: 978-991, 2011.
    • (2011) Lab Invest , vol.91 , pp. 978-991
    • Han, Y.1    Ma, F.Y.2    Tesch, G.H.3    Manthey, C.L.4    Nikolic-Paterson, D.J.5
  • 25
    • 0035188299 scopus 로고    scopus 로고
    • Predictive power of the second renal biopsy in lupus nephritis: Significance of macrophages
    • Hill GS, Delahousse M, Nochy D, Remy P, Mignon F, Mery JP, Bariety J. Predictive power of the second renal biopsy in lupus nephritis: significance of macrophages. Kidney Int 59: 304-316, 2001.
    • (2001) Kidney Int , vol.59 , pp. 304-316
    • Hill, G.S.1    Delahousse, M.2    Nochy, D.3    Remy, P.4    Mignon, F.5    Mery, J.P.6    Bariety, J.7
  • 26
    • 0021241184 scopus 로고
    • Macrophage-induced glomerular injury. Cell transfer studies in passive autologous antiglomerular basement membrane antibody-initiated experimental glomerulonephritis
    • Holdsworth SR, Neale TJ. Macrophage-induced glomerular injury. Cell transfer studies in passive autologous antiglomerular basement membrane antibody-initiated experimental glomerulonephritis. Lab Invest 51: 172-180, 1984.
    • (1984) Lab Invest , vol.51 , pp. 172-180
    • Holdsworth, S.R.1    Neale, T.J.2
  • 27
    • 0019371079 scopus 로고
    • Abrogation of macrophagedependent injury in experimental glomerulonephritis in the rabbit. Use of an antimacrophage serum
    • Holdsworth SR, Neale TJ, Wilson CB. Abrogation of macrophagedependent injury in experimental glomerulonephritis in the rabbit. Use of an antimacrophage serum. J Clin Invest 68: 686-698, 1981.
    • (1981) J Clin Invest , vol.68 , pp. 686-698
    • Holdsworth, S.R.1    Neale, T.J.2    Wilson, C.B.3
  • 30
    • 0037378759 scopus 로고    scopus 로고
    • Interferon-gamma augments acute macrophage-mediated renal injury via a glucocorticoidsensitive mechanism
    • Ikezumi Y, Atkins RC, Nikolic-Paterson DJ. Interferon-gamma augments acute macrophage-mediated renal injury via a glucocorticoidsensitive mechanism. J Am Soc Nephrol 14: 888-898, 2003.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 888-898
    • Ikezumi, Y.1    Atkins, R.C.2    Nikolic-Paterson, D.J.3
  • 31
    • 3042628478 scopus 로고    scopus 로고
    • Macrophagemediated renal injury is dependent on signaling via the JNK pathway
    • Ikezumi Y, Hurst L, Atkins RC, Nikolic-Paterson DJ. Macrophagemediated renal injury is dependent on signaling via the JNK pathway. J Am Soc Nephrol 15: 1775-1784, 2004.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 1775-1784
    • Ikezumi, Y.1    Hurst, L.2    Atkins, R.C.3    Nikolic-Paterson, D.J.4
  • 32
    • 0037213079 scopus 로고    scopus 로고
    • Adoptive transfer studies demonstrate that macrophages can induce proteinuria and mesangial cell proliferation
    • Ikezumi Y, Hurst LA, Masaki T, Atkins RC, Nikolic-Paterson DJ. Adoptive transfer studies demonstrate that macrophages can induce proteinuria and mesangial cell proliferation. Kidney Int 63: 83-95, 2003.
    • (2003) Kidney Int , vol.63 , pp. 83-95
    • Ikezumi, Y.1    Hurst, L.A.2    Masaki, T.3    Atkins, R.C.4    Nikolic-Paterson, D.J.5
  • 34
    • 84874206502 scopus 로고    scopus 로고
    • Translating tolerogenic therapies to the clinic: Where do we stand?
    • Issa F, Wood KJ. Translating tolerogenic therapies to the clinic: where do we stand? Front Immunol 3: 254, 2012.
    • (2012) Front Immunol , vol.3 , pp. 254
    • Issa, F.1    Wood, K.J.2
  • 35
    • 33646201785 scopus 로고    scopus 로고
    • Macrophages contribute to the initiation of ischaemic acute renal failure in rats
    • Jo SK, Sung SA, Cho WY, Go KJ, Kim HK. Macrophages contribute to the initiation of ischaemic acute renal failure in rats. Nephrol Dial Transplant 21: 1231-1239, 2006.
    • (2006) Nephrol Dial Transplant , vol.21 , pp. 1231-1239
    • Jo, S.K.1    Sung, S.A.2    Cho, W.Y.3    Go, K.J.4    Kim, H.K.5
  • 38
    • 77956254268 scopus 로고    scopus 로고
    • Depletion of kidney CD11c+ F4/80+ cells impairs the recovery process in ischaemia/reperfusion-induced acute kidney injury
    • Kim MG, Boo CS, Ko YS, Lee HY, Cho WY, Kim HK, Jo SK. Depletion of kidney CD11c+ F4/80+ cells impairs the recovery process in ischaemia/reperfusion-induced acute kidney injury. Nephrol Dial Transplant 25: 2908-2921, 2010.
    • (2010) Nephrol Dial Transplant , vol.25 , pp. 2908-2921
    • Kim, M.G.1    Boo, C.S.2    Ko, Y.S.3    Lee, H.Y.4    Cho, W.Y.5    Kim, H.K.6    Jo, S.K.7
  • 41
    • 0035313470 scopus 로고    scopus 로고
    • Macrophages transfected with adenovirus to express IL-4 reduce inflammation in experimental glomerulonephritis
    • Kluth DC, Ainslie CV, Pearce WP, Finlay S, Clarke D, Anegon I, Rees AJ. Macrophages transfected with adenovirus to express IL-4 reduce inflammation in experimental glomerulonephritis. J Immunol 166: 4728-4736, 2001.
    • (2001) J Immunol , vol.166 , pp. 4728-4736
    • Kluth, D.C.1    Ainslie, C.V.2    Pearce, W.P.3    Finlay, S.4    Clarke, D.5    Anegon, I.6    Rees, A.J.7
  • 42
    • 3242776999 scopus 로고    scopus 로고
    • Multiple facets of macrophages in renal injury
    • Kluth DC, Erwig LP, Rees AJ. Multiple facets of macrophages in renal injury. Kidney Int 66: 542-557, 2004.
    • (2004) Kidney Int , vol.66 , pp. 542-557
    • Kluth, D.C.1    Erwig, L.P.2    Rees, A.J.3
  • 43
    • 42449105787 scopus 로고    scopus 로고
    • Macrophages contribute to the development of renal fibrosis following ischaemia/reperfusion-induced acute kidney injury
    • Ko GJ, Boo CS, Jo SK, Cho WY, Kim HK. Macrophages contribute to the development of renal fibrosis following ischaemia/reperfusion-induced acute kidney injury. Nephrol Dial Transplant 23: 842-852, 2008.
    • (2008) Nephrol Dial Transplant , vol.23 , pp. 842-852
    • Ko, G.J.1    Boo, C.S.2    Jo, S.K.3    Cho, W.Y.4    Kim, H.K.5
  • 45
    • 0032427023 scopus 로고    scopus 로고
    • Cellular interactions in the pathogenesis of lupus nephritis: The role of T cells and macrophages in the amplification of the inflammatory process in the kidney
    • Kuroiwa T, Lee EG. Cellular interactions in the pathogenesis of lupus nephritis: the role of T cells and macrophages in the amplification of the inflammatory process in the kidney. Lupus 7: 597-603, 1998.
    • (1998) Lupus , vol.7 , pp. 597-603
    • Kuroiwa, T.1    Lee, E.G.2
  • 46
    • 80355146399 scopus 로고    scopus 로고
    • Transcriptional regulation of macrophage polarization: Enabling diversity with identity
    • Lawrence T, Natoli G. Transcriptional regulation of macrophage polarization: enabling diversity with identity. Nat Rev Immunol 11: 750-761, 2011.
    • (2011) Nat Rev Immunol , vol.11 , pp. 750-761
    • Lawrence, T.1    Natoli, G.2
  • 47
    • 78349309119 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells attenuate cisplatin-induced nephrotoxicity in mice
    • Lee H, Nho D, Chung HS, Shin MK, Kim SH, Bae H. CD4+CD25+ regulatory T cells attenuate cisplatin-induced nephrotoxicity in mice. Kidney Int 78: 1100-1109, 2010.
    • (2010) Kidney Int , vol.78 , pp. 1100-1109
    • Lee, H.1    Nho, D.2    Chung, H.S.3    Shin, M.K.4    Kim, S.H.5    Bae, H.6
  • 50
    • 77953890977 scopus 로고    scopus 로고
    • Macrophages, dendritic cells, and kidney ischemiareperfusion injury
    • Li L, Okusa MD. Macrophages, dendritic cells, and kidney ischemiareperfusion injury. Semin Nephrol 30: 268-277, 2010.
    • (2010) Semin Nephrol , vol.30 , pp. 268-277
    • Li, L.1    Okusa, M.D.2
  • 51
    • 84866122642 scopus 로고    scopus 로고
    • Inflammation in diabetic nephropathy
    • Lim AK, Tesch GH. Inflammation in diabetic nephropathy. Mediators Inflamm 2012: 146154, 2012.
    • (2012) Mediators Inflamm , vol.2012 , pp. 146154
    • Lim, A.K.1    Tesch, G.H.2
  • 53
    • 44449140105 scopus 로고    scopus 로고
    • Unique expression of suppressor of cytokine signaling 3 is essential for classical macrophage activation in rodents in vitro and in vivo
    • Liu Y, Stewart KN, Bishop E, Marek CJ, Kluth DC, Rees AJ, Wilson HM. Unique expression of suppressor of cytokine signaling 3 is essential for classical macrophage activation in rodents in vitro and in vivo. J Immunol 180: 6270-6278, 2008.
    • (2008) J Immunol , vol.180 , pp. 6270-6278
    • Liu, Y.1    Stewart, K.N.2    Bishop, E.3    Marek, C.J.4    Kluth, D.C.5    Rees, A.J.6    Wilson, H.M.7
  • 54
    • 37349035351 scopus 로고    scopus 로고
    • Increased macrophage infiltration and fractalkine expression in cisplatininduced acute renal failure in mice
    • Lu LH, Oh DJ, Dursun B, He Z, Hoke TS, Faubel S, Edelstein CL. Increased macrophage infiltration and fractalkine expression in cisplatininduced acute renal failure in mice. J Pharmacol Exp Ther 324: 111-117, 2008.
    • (2008) J Pharmacol Exp Ther , vol.324 , pp. 111-117
    • Lu, L.H.1    Oh, D.J.2    Dursun, B.3    He, Z.4    Hoke, T.S.5    Faubel, S.6    Edelstein, C.L.7
  • 55
    • 63449084230 scopus 로고    scopus 로고
    • Blockade of the c-Jun amino terminal kinase prevents crescent formation and halts established anti-GBM glomerulonephritis in the rat
    • Ma FY, Flanc RS, Tesch GH, Bennett BL, Friedman GC, Nikolic-Paterson DJ. Blockade of the c-Jun amino terminal kinase prevents crescent formation and halts established anti-GBM glomerulonephritis in the rat. Lab Invest 89: 470-484, 2009.
    • (2009) Lab Invest , vol.89 , pp. 470-484
    • Ma, F.Y.1    Flanc, R.S.2    Tesch, G.H.3    Bennett, B.L.4    Friedman, G.C.5    Nikolic-Paterson, D.J.6
  • 56
    • 77953884129 scopus 로고    scopus 로고
    • Macrophage signaling pathways: A novel target in renal disease
    • Ma FY, Ikezumi Y, Nikolic-Paterson DJ. Macrophage signaling pathways: a novel target in renal disease. Semin Nephrol 30: 334-344, 2010.
    • (2010) Semin Nephrol , vol.30 , pp. 334-344
    • Ma, F.Y.1    Ikezumi, Y.2    Nikolic-Paterson, D.J.3
  • 60
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • Mosser DM, Edwards JP. Exploring the full spectrum of macrophage activation. Nat Rev Immunol 8: 958-969, 2008.
    • (2008) Nat Rev Immunol , vol.8 , pp. 958-969
    • Mosser, D.M.1    Edwards, J.P.2
  • 61
    • 27744603002 scopus 로고    scopus 로고
    • Hypoxia regulates macrophage functions in inflammation
    • Murdoch C, Muthana M, Lewis CE. Hypoxia regulates macrophage functions in inflammation. J Immunol 175: 6257-6263, 2005.
    • (2005) J Immunol , vol.175 , pp. 6257-6263
    • Murdoch, C.1    Muthana, M.2    Lewis, C.E.3
  • 68
    • 33646191735 scopus 로고    scopus 로고
    • Effects of low molecular weight heparin in obstructed kidneys: Decrease of collagen, fibronectin and TGF-beta, and increase of chondroitin/dermatan sulfate proteoglycans and macrophage infiltration
    • Pecly IM, Goncalves RG, Rangel EP, Takiya CM, Taboada FS, Martinusso CA, Pavao MS, Leite M Jr. Effects of low molecular weight heparin in obstructed kidneys: decrease of collagen, fibronectin and TGF-beta, and increase of chondroitin/dermatan sulfate proteoglycans and macrophage infiltration. Nephrol Dial Transplant 21: 1212-1222, 2006.
    • (2006) Nephrol Dial Transplant , vol.21 , pp. 1212-1222
    • Pecly, I.M.1    Goncalves, R.G.2    Rangel, E.P.3    Takiya, C.M.4    Taboada, F.S.5    Martinusso, C.A.6    Pavao, M.S.7    Leite Jr., M.8
  • 70
    • 63149088164 scopus 로고    scopus 로고
    • Trophic macrophages in development and disease
    • Pollard JW. Trophic macrophages in development and disease. Nat Rev Immunol 9: 259-270, 2009.
    • (2009) Nat Rev Immunol , vol.9 , pp. 259-270
    • Pollard, J.W.1
  • 71
    • 84920506276 scopus 로고    scopus 로고
    • SOCS1 regulates the IFN but not NFkappaB pathway in TLR-stimulated human monocytes and macrophages
    • Prele CM, Woodward EA, Bisley J, Keith-Magee A, Nicholson SE, Hart PH. SOCS1 regulates the IFN but not NFkappaB pathway in TLR-stimulated human monocytes and macrophages. J Immunol 181: 8018-8026, 2008.
    • (2008) J Immunol , vol.181 , pp. 8018-8026
    • Prele, C.M.1    Woodward, E.A.2    Bisley, J.3    Keith-Magee, A.4    Nicholson, S.E.5    Hart, P.H.6
  • 72
    • 20844440200 scopus 로고    scopus 로고
    • p38 MAP kinase inhibition ameliorates cisplatin nephrotoxicity in mice
    • Ramesh G, Reeves WB. p38 MAP kinase inhibition ameliorates cisplatin nephrotoxicity in mice. Am J Physiol Renal Physiol 289: F166-F174, 2005.
    • (2005) Am J Physiol Renal Physiol , vol.289
    • Ramesh, G.1    Reeves, W.B.2
  • 73
    • 55849103960 scopus 로고    scopus 로고
    • Macrophage diversity in renal injury and repair
    • Ricardo SD, van Goor H, Eddy AA. Macrophage diversity in renal injury and repair. J Clin Invest 118: 3522-3530, 2008.
    • (2008) J Clin Invest , vol.118 , pp. 3522-3530
    • Ricardo, S.D.1    van Goor, H.2    Eddy, A.A.3
  • 74
    • 78650880591 scopus 로고    scopus 로고
    • Bacterial CpG-DNA accelerates Alport glomerulosclerosis by inducing an M1 macrophage phenotype and tumor necrosis factor-alpha-mediated podocyte loss
    • Ryu M, Kulkarni OP, Radomska E, Miosge N, Gross O, Anders HJ. Bacterial CpG-DNA accelerates Alport glomerulosclerosis by inducing an M1 macrophage phenotype and tumor necrosis factor-alpha-mediated podocyte loss. Kidney Int 79: 189-198, 2011.
    • (2011) Kidney Int , vol.79 , pp. 189-198
    • Ryu, M.1    Kulkarni, O.P.2    Radomska, E.3    Miosge, N.4    Gross, O.5    Anders, H.J.6
  • 77
    • 26944492287 scopus 로고    scopus 로고
    • Macrophages and progressive tubulointerstitial disease
    • Sean Eardley K, Cockwell P. Macrophages and progressive tubulointerstitial disease. Kidney Int 68: 437-455, 2005.
    • (2005) Kidney Int , vol.68 , pp. 437-455
    • Sean Eardley, K.1    Cockwell, P.2
  • 78
    • 34248172324 scopus 로고    scopus 로고
    • Altered macrophage differentiation and immune dysfunction in tumor development
    • Sica A, Bronte V. Altered macrophage differentiation and immune dysfunction in tumor development. J Clin Invest 117: 1155-1166, 2007.
    • (2007) J Clin Invest , vol.117 , pp. 1155-1166
    • Sica, A.1    Bronte, V.2
  • 79
    • 33845734736 scopus 로고    scopus 로고
    • Reduction of renal fibrosis as a result of liposome encapsulated clodronate induced macrophage depletion after unilateral ureteral obstruction in rats
    • Sung SA, Jo SK, Cho WY, Won NH, Kim HK. Reduction of renal fibrosis as a result of liposome encapsulated clodronate induced macrophage depletion after unilateral ureteral obstruction in rats. Nephron Exp Nephrol 105: 1-9, 2007.
    • (2007) Nephron Exp Nephrol , vol.105 , pp. 1-9
    • Sung, S.A.1    Jo, S.K.2    Cho, W.Y.3    Won, N.H.4    Kim, H.K.5
  • 80
    • 77749291745 scopus 로고    scopus 로고
    • Macrophage matrix metalloproteinase-9 mediates epithelial-mesenchymal transition in vitro in murine renal tubular cells
    • Tan TK, Zheng G, Hsu TT, Wang Y, Lee VW, Tian X, Cao Q, Harris DC. Macrophage matrix metalloproteinase-9 mediates epithelial-mesenchymal transition in vitro in murine renal tubular cells. Am J Pathol 176: 1256-1270, 2010.
    • (2010) Am J Pathol , vol.176 , pp. 1256-1270
    • Tan, T.K.1    Zheng, G.2    Hsu, T.T.3    Wang, Y.4    Lee, V.W.5    Tian, X.6    Cao, Q.7    Harris, D.C.8
  • 81
    • 34447504865 scopus 로고    scopus 로고
    • Differential expression of Toll-like receptors in murine peritoneal macrophages in vitro on treatment with cisplatin
    • Tarang S, Sodhi A, Chauhan P. Differential expression of Toll-like receptors in murine peritoneal macrophages in vitro on treatment with cisplatin. Int Immunol 19: 635-643, 2007.
    • (2007) Int Immunol , vol.19 , pp. 635-643
    • Tarang, S.1    Sodhi, A.2    Chauhan, P.3
  • 84
    • 38049042218 scopus 로고    scopus 로고
    • Macrophage involvement in the kidney repair phase after ischaemia/ reperfusion injury
    • Vinuesa E, Hotter G, Jung M, Herrero-Fresneda I, Torras J, Sola A. Macrophage involvement in the kidney repair phase after ischaemia/ reperfusion injury. J Pathol 214: 104-113, 2008.
    • (2008) J Pathol , vol.214 , pp. 104-113
    • Vinuesa, E.1    Hotter, G.2    Jung, M.3    Herrero-Fresneda, I.4    Torras, J.5    Sola, A.6
  • 87
    • 78651398351 scopus 로고    scopus 로고
    • Macrophages in renal disease
    • Wang Y, Harris DC. Macrophages in renal disease. J Am Soc Nephrol 22: 21-27, 2011.
    • (2011) J Am Soc Nephrol , vol.22 , pp. 21-27
    • Wang, Y.1    Harris, D.C.2
  • 91
    • 21244475215 scopus 로고    scopus 로고
    • Inhibition of macrophage nuclear factor-kappaB leads to a dominant anti-inflammatory phenotype that attenuates glomerular inflammation in vivo
    • Wilson HM, Chettibi S, Jobin C, Walbaum D, Rees AJ, Kluth DC. Inhibition of macrophage nuclear factor-kappaB leads to a dominant anti-inflammatory phenotype that attenuates glomerular inflammation in vivo. Am J Pathol 167: 27-37, 2005.
    • (2005) Am J Pathol , vol.167 , pp. 27-37
    • Wilson, H.M.1    Chettibi, S.2    Jobin, C.3    Walbaum, D.4    Rees, A.J.5    Kluth, D.C.6
  • 92
    • 25744441557 scopus 로고    scopus 로고
    • Targeting genetically modified macrophages to the glomerulus
    • Wilson HM, Kluth DC. Targeting genetically modified macrophages to the glomerulus. Nephron Exp Nephrol 94: 113-118, 2003.
    • (2003) Nephron Exp Nephrol , vol.94 , pp. 113-118
    • Wilson, H.M.1    Kluth, D.C.2
  • 93
    • 0036941189 scopus 로고    scopus 로고
    • Bone-marrow-derived macrophages genetically modified to produce IL-10 reduce injury in experimental glomerulonephritis
    • Wilson HM, Stewart KN, Brown PA, Anegon I, Chettibi S, Rees AJ, Kluth DC. Bone-marrow-derived macrophages genetically modified to produce IL-10 reduce injury in experimental glomerulonephritis. Mol Ther 6: 710-717, 2002.
    • (2002) Mol Ther , vol.6 , pp. 710-717
    • Wilson, H.M.1    Stewart, K.N.2    Brown, P.A.3    Anegon, I.4    Chettibi, S.5    Rees, A.J.6    Kluth, D.C.7
  • 94
    • 23044492777 scopus 로고    scopus 로고
    • DNA vaccination with naked DNA encoding MCP-1 and RANTES protects against renal injury in adriamycin nephropathy
    • Wu H, Wang Y, Tay YC, Zheng G, Zhang C, Alexander SI, Harris DC. DNA vaccination with naked DNA encoding MCP-1 and RANTES protects against renal injury in adriamycin nephropathy. Kidney Int 67: 2178-2186, 2005.
    • (2005) Kidney Int , vol.67 , pp. 2178-2186
    • Wu, H.1    Wang, Y.2    Tay, Y.C.3    Zheng, G.4    Zhang, C.5    Alexander, S.I.6    Harris, D.C.7
  • 97
    • 0035164441 scopus 로고    scopus 로고
    • Genetically modified bone marrow-derived vehicle cells site specifically deliver an anti-inflammatory cytokine to inflamed interstitium of obstructive nephropathy
    • Yamagishi H, Yokoo T, Imasawa T, Mitarai T, Kawamura T, Utsunomiya Y. Genetically modified bone marrow-derived vehicle cells site specifically deliver an anti-inflammatory cytokine to inflamed interstitium of obstructive nephropathy. J Immunol 166: 609-616, 2001.
    • (2001) J Immunol , vol.166 , pp. 609-616
    • Yamagishi, H.1    Yokoo, T.2    Imasawa, T.3    Mitarai, T.4    Kawamura, T.5    Utsunomiya, Y.6
  • 100
    • 0037406922 scopus 로고    scopus 로고
    • Urokinase receptor modulates cellular and angiogenic responses in obstructive nephropathy
    • Zhang G, Kim H, Cai X, Lopez-Guisa JM, Carmeliet P, Eddy AA. Urokinase receptor modulates cellular and angiogenic responses in obstructive nephropathy. J Am Soc Nephrol 14: 1234-1253, 2003.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 1234-1253
    • Zhang, G.1    Kim, H.2    Cai, X.3    Lopez-Guisa, J.M.4    Carmeliet, P.5    Eddy, A.A.6
  • 103
    • 68449094056 scopus 로고    scopus 로고
    • Disruption of E-cadherin by matrix metalloproteinase directly mediates epithelial-mesenchymal transition downstream of transforming growth factor-beta1 in renal tubular epithelial cells
    • Zheng G, Lyons JG, Tan TK, Wang Y, Hsu TT, Min D, Succar L, Rangan GK, Hu M, Henderson BR, Alexander SI, Harris DC. Disruption of E-cadherin by matrix metalloproteinase directly mediates epithelial-mesenchymal transition downstream of transforming growth factor-beta1 in renal tubular epithelial cells. Am J Pathol 175: 580-591, 2009.
    • (2009) Am J Pathol , vol.175 , pp. 580-591
    • Zheng, G.1    Lyons, J.G.2    Tan, T.K.3    Wang, Y.4    Hsu, T.T.5    Min, D.6    Succar, L.7    Rangan, G.K.8    Hu, M.9    Henderson, B.R.10    Alexander, S.I.11    Harris, D.C.12


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.