Integrated energy and flux balance based multiobjective framework for large-scale metabolic networks

Annals of Biomedical Engineering

Volumn 35, Issue 6, 2007, Pages 863-885

  Nagrath, Deepak ^a,b   Avila Elchiver, Marco ^a,b   Berthiaume, Francois ^a,b   Tilles, Arno W ^a,b   Messac, Achille ^c   Yarmush, Martin L ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b SHRINERS HOSPITALS FOR CHILDREN   (United States)

^c RENSSELAER POLYTECHNIC INSTITUTE   (United States)

Author keywords

Bioartificial liver; Energy balance analysis; Flux balance analysis; Hepatocytes; Metabolic networks; Multi objective optimization; Pareto optimality

Indexed keywords

BIOLOGICAL ORGANS; COMPUTATIONAL METHODS; ENERGY BALANCE; PARETO PRINCIPLE; THERMODYNAMICS;

BIOARTIFICIAL LIVER; ENERGY BALANCE ANALYSIS; FLUX BALANCE ANALYSIS; HEPATOCYTES; METABOLIC NETWORKS; MULTI OBJECTIVE OPTIMIZATION;

METABOLISM;

GLUCOSE; MULTIENZYME COMPLEX; PROTEOME;

ALGORITHM; ANIMAL; ARTICLE; BIOLOGICAL MODEL; COMPUTER SIMULATION; ENERGY METABOLISM; EVALUATION; GLUCONEOGENESIS; GLYCOLYSIS; HUMAN; LIVER; LIVER CELL; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; SYSTEM ANALYSIS; THERMODYNAMICS;

ALGORITHMS; ANIMALS; COMPUTER SIMULATION; ENERGY METABOLISM; GLUCONEOGENESIS; GLUCOSE; GLYCOLYSIS; HEPATOCYTES; HUMANS; LIVER; MODELS, BIOLOGICAL; MULTIENZYME COMPLEXES; PROTEOME; SIGNAL TRANSDUCTION; SYSTEMS INTEGRATION; THERMODYNAMICS;

EID: 34249708861     PISSN: 00906964     EISSN: 15739686     Source Type: Journal    
DOI: 10.1007/s10439-007-9283-0     Document Type: Conference Paper

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