SCOPUS 정보 검색 플랫폼

Volumn 66, Issue , 2013, Pages 221-227

Exploring 4-substituted-2-thiazolylhydrazones from 2-, 3-, and 4-acetylpyridine as selective and reversible hMAO-B inhibitors

(9) Chimenti, Paola a Petzer, Anél b Carradori, Simone a D'Ascenzio, Melissa a Silvestri, Romano a Alcaro, Stefano c Ortuso, Francesco c Petzer, Jacobus P b Secci, Daniela a

a SAPIENZA UNIVERSITY OF ROME (Italy)

b NORTH WEST UNIVERSITY (South Africa)

c UNIVERSITY MAGNA GRAECIA OF CATANZARO (Italy)

Author keywords

Acetylpyridine; Molecular modelling; Monoamine oxidase; Reversibility; Thiazole

Indexed keywords

4 METHYL 2 [2 [1 (PYRIDIN 2 YL)ETHYLIDENE]HYDRAZINYL]THIAZOLE; 4 METHYL 2 [2 [1 (PYRIDIN 3 YL)ETHYLIDENE]HYDRAZINYL]THIAZOLE; 4 METHYL 2 [2 [1 (PYRIDIN 4 YL)ETHYLIDENE]HYDRAZINYL]THIAZOLE; 4 PHENYL 2 [2 [1 (PYRIDIN 2 YL)ETHYLIDENE]HYDRAZINYL]THIAZOLE; 4 PHENYL 2 [2 [1 (PYRIDIN 3 YL)ETHYLIDINE]HYDRAZINYL]THIAZOLE; 4 PHENYL 2 [2 [1 (PYRIDIN 4 YL)ETHYLIDENE]HYDRAZINYL]THIAZOLE; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; HYDRAZONE DERIVATIVE; MONOAMINE OXIDASE INHIBITOR; UNCLASSIFIED DRUG; 4 PHENYL 2 [2 [1 (PYRIDIN 3 YL)ETHYLIDENE]HYDRAZINYL]THIAZOLE; HYDROGEN; PYRIDINE DERIVATIVE; RECOMBINANT ENZYME; THIAZOLE DERIVATIVE;

ARTICLE; ENZYME INHIBITION; IC 50; STEREOSPECIFICITY; ANIMAL CELL; BINDING AFFINITY; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG BINDING SITE; DRUG POTENCY; DRUG STABILITY; DRUG SYNTHESIS; ENZYME ACTIVE SITE; ENZYME ACTIVITY; HUMAN; HYDROGEN BOND; IC50; IN VITRO STUDY; INCUBATION TIME; INSECT CELL; MOLECULAR DYNAMICS; MOLECULAR RECOGNITION; NONHUMAN; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION; THIN LAYER CHROMATOGRAPHY;

EID: 84879467536 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2013.05.032 Document Type: Article

Times cited : (26)

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