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Volumn 169, Issue 6, 2013, Pages 1189-1202

Mechanistic analysis of the function of agonists and allosteric modulators: Reconciling two-state and operational models

Author keywords

agonist efficacy; G protein coupled receptors; mathematical modelling; model fitting; negative allosteric modulators; operational model of agonism; operational model of allosterism; parameter estimation; positive allosteric modulators; two state receptor model

Indexed keywords

AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; DRUG; RECEPTOR; RECEPTOR AGONIST; UNCLASSIFIED DRUG;

EID: 84879339183     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12231     Document Type: Review
Times cited : (23)

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