-
1
-
-
0021058380
-
Operational models of pharmacological agonism
-
Black JW and Leff P (1983) Operational models of pharmacological agonism. Proc R Soc Lond B 220:141-162.
-
(1983)
Proc R Soc Lond B
, vol.220
, pp. 141-162
-
-
Black, J.W.1
Leff, P.2
-
2
-
-
0019790028
-
Conformational changes and drug action
-
Burgen AS (1981) Conformational changes and drug action. Fed Proc 40:2723-2728.
-
(1981)
Fed Proc
, vol.40
, pp. 2723-2728
-
-
Burgen, A.S.1
-
3
-
-
0009196548
-
Quantification of allosteric interactions at G protein-coupled receptors using radioligand binding assays
-
(Enna SJ ed), John Wiley & Sons, Inc., New York
-
Christopoulos A (2000) Quantification of allosteric interactions at G protein-coupled receptors using radioligand binding assays, in Current Protocols in Pharmacology (Enna SJ ed), John Wiley & Sons, Inc., New York.
-
(2000)
Current Protocols in Pharmacology
-
-
Christopoulos, A.1
-
4
-
-
0036490942
-
Allosteric binding sites on cell-surface receptors: Novel targets for drug discovery
-
Christopoulos A (2002) Allosteric binding sites on cell-surface receptors: novel targets for drug discovery. Nat Rev Drug Discov 1:198-210.
-
(2002)
Nat Rev Drug Discov
, vol.1
, pp. 198-210
-
-
Christopoulos, A.1
-
5
-
-
0017105216
-
The inhibitory effect of gallamine on muscarinic receptors
-
Clark AL and Mitchelson F (1976) The inhibitory effect of gallamine on muscarinic receptors. Br J Pharmacol 58:323-331.
-
(1976)
Br J Pharmacol
, vol.58
, pp. 323-331
-
-
Clark, A.L.1
Mitchelson, F.2
-
6
-
-
0022541659
-
Inverse agonists', cooperativity and drug action at benzodiazepine receptors
-
Ehlert FJ (1986) 'Inverse agonists', cooperativity and drug action at benzodiazepine receptors. Trends Pharmacol Sci 7:28-32.
-
(1986)
Trends Pharmacol Sci
, vol.7
, pp. 28-32
-
-
Ehlert, F.J.1
-
7
-
-
0023958554
-
Estimation of the affinities of allosteric ligands using radioligand binding and pharmacological null methods
-
Ehlert FJ (1988a) Estimation of the affinities of allosteric ligands using radioligand binding and pharmacological null methods. Mol Pharmacol 33:187-194.
-
(1988)
Mol Pharmacol
, vol.33
, pp. 187-194
-
-
Ehlert, F.J.1
-
8
-
-
0023794328
-
Gallamine allosterically antagonizes muscarinic receptor-mediated inhibition of adenylate cyclase activity in the rat myocardium
-
Ehlert FJ (1988b) Gallamine allosterically antagonizes muscarinic receptor-mediated inhibition of adenylate cyclase activity in the rat myocardium. J Pharmacol Exp Ther 247:596-602.
-
(1988)
J Pharmacol Exp Ther
, vol.247
, pp. 596-602
-
-
Ehlert, F.J.1
-
9
-
-
27144508201
-
Ternary complex model
-
Christopoulos A ed CRC Press, Boca Raton, FL
-
Ehlert FJ (2000) Ternary complex model, in Biomedical Applications of Computer Modeling (Christopoulos A ed) pp 21-85, CRC Press, Boca Raton, FL.
-
(2000)
Biomedical Applications of Computer Modeling
, pp. 21-85
-
-
Ehlert, F.J.1
-
10
-
-
27144552759
-
Estimation of agonist activity and relative efficacy at G protein-coupled receptors: Mutational analysis and characterization of receptor subtypes
-
Ehlert FJ and Griffin MT (2001) Estimation of agonist activity and relative efficacy at G protein-coupled receptors: mutational analysis and characterization of receptor subtypes. Anal Pharmacol 2:34-48.
-
(2001)
Anal Pharmacol
, vol.2
, pp. 34-48
-
-
Ehlert, F.J.1
Griffin, M.T.2
-
12
-
-
0002355204
-
The use of b-haloalkylamines in the differentiation of receptors and in the determination of dissociation constants of receptor-agonist complexes
-
Furchgott RF (1966) The use of b-haloalkylamines in the differentiation of receptors and in the determination of dissociation constants of receptor-agonist complexes. Adv Drug Res 3:21-55.
-
(1966)
Adv Drug Res
, vol.3
, pp. 21-55
-
-
Furchgott, R.F.1
-
13
-
-
0033669603
-
Modeling the functional effects of allosteric modulators at pharmacological receptors: An extension of the two-state model of receptor activation
-
Hall DA (2000) Modeling the functional effects of allosteric modulators at pharmacological receptors: an extension of the two-state model of receptor activation. Mol Pharmacol 58:1412-1423.
-
(2000)
Mol Pharmacol
, vol.58
, pp. 1412-1423
-
-
Hall, D.A.1
-
14
-
-
0022469652
-
Binding profile of a novel cardioselective muscarine receptor antagonist, AF-DX 116, to membranes of peripheral tissues and brain in the rat
-
Hammer R, Giraldo E, Schiavi GB, Monferini E, and Ladinsky H (1986) Binding profile of a novel cardioselective muscarine receptor antagonist, AF-DX 116, to membranes of peripheral tissues and brain in the rat. Life Sci 38:1653-1662.
-
(1986)
Life Sci
, vol.38
, pp. 1653-1662
-
-
Hammer, R.1
Giraldo, E.2
Schiavi, G.B.3
Monferini, E.4
Ladinsky, H.5
-
16
-
-
0020042463
-
In vitro studies on the cardiac activity of prenalterol with reference to use in congestive heart failure
-
Kenakin TP and Beek D (1982) In vitro studies on the cardiac activity of prenalterol with reference to use in congestive heart failure. J Pharmacol Exp Ther 220:77-85.
-
(1982)
J Pharmacol Exp Ther
, vol.220
, pp. 77-85
-
-
Kenakin, T.P.1
Beek, D.2
-
17
-
-
0029126526
-
Detection, quantitation and verification of allosteric interactions of agents with labeled and unlabeled ligands at G protein-coupled receptors: Interactions of strychnine and acetylcholine at muscarinic receptors
-
Lazareno S and Birdsall NJ (1995) Detection, quantitation and verification of allosteric interactions of agents with labeled and unlabeled ligands at G protein-coupled receptors: interactions of strychnine and acetylcholine at muscarinic receptors. Mol Pharmacol 48:362-378.
-
(1995)
Mol Pharmacol
, vol.48
, pp. 362-378
-
-
Lazareno, S.1
Birdsall, N.J.2
-
18
-
-
0019430370
-
An analysis of functional antagonism and synergism
-
Mackay D (1981) An analysis of functional antagonism and synergism. Br J Pharmacol 73:127-134.
-
(1981)
Br J Pharmacol
, vol.73
, pp. 127-134
-
-
Mackay, D.1
-
19
-
-
0001004352
-
The pharmacology of Flaxedil, with observations on certain analogs
-
Riker WF Jr and Wescoe WC (1951) The pharmacology of Flaxedil, with observations on certain analogs. Ann NY Acad Sci 54:373-394.
-
(1951)
Ann NY Acad Sci
, vol.54
, pp. 373-394
-
-
Riker Jr., W.F.1
Wescoe, W.C.2
-
20
-
-
0010673662
-
A modification of receptor theory
-
Stephenson RP (1956) A modification of receptor theory. Br J Pharmacol 11:379-393.
-
(1956)
Br J Pharmacol
, vol.11
, pp. 379-393
-
-
Stephenson, R.P.1
-
21
-
-
0020533362
-
Modification of the binding properties of muscarinic receptors by gallamine
-
Stockton JM, Birdsall NJ, Burgen AS, and Hulme EC (1983) Modification of the binding properties of muscarinic receptors by gallamine. Mol Pharmacol 23:551-557.
-
(1983)
Mol Pharmacol
, vol.23
, pp. 551-557
-
-
Stockton, J.M.1
Birdsall, N.J.2
Burgen, A.S.3
Hulme, E.C.4
-
22
-
-
27144538712
-
Flaxedil, a new curarizing agent
-
Walton FA (1950) Flaxedil, a new curarizing agent. Can Med Assoc J 63:123-129.
-
(1950)
Can Med Assoc J
, vol.63
, pp. 123-129
-
-
Walton, F.A.1
|