Quantitative analysis reveals multiple mechanisms of allosteric modulation of the mGlu5 receptor in rat astroglia

Molecular Pharmacology

Volumn 79, Issue 5, 2011, Pages 874-885

  Bradley, Sophie J ^a   Langmead, Christopher J ^b   Watson, Jeannette M ^c   Challiss, R A John ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b Heptares Therapeutics Ltd   (United Kingdom)

^c GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; 3,5 DIHYDROXYPHENYLGLYCINE; INOSITOL PHOSPHATE; METABOTROPIC RECEPTOR 5; QUISQUALIC ACID;

ALLOSTERISM; ANIMAL CELL; ARTICLE; BINDING ASSAY; CALCIUM SIGNALING; CONTROLLED STUDY; MACROGLIA; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; RECEPTOR AFFINITY; RECEPTOR BINDING;

ALLOSTERIC REGULATION; ANIMALS; ASTROCYTES; EXCITATORY AMINO ACID ANTAGONISTS; PYRIDINES; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; RECEPTORS, METABOTROPIC GLUTAMATE;

EID: 79954988501     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.110.068882     Document Type: Article

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