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Volumn 10, Issue 8, 2013, Pages 995-1002

Overexpression of integrin-linked kinase promotes lung cancer cell migration and invasion via NF-κB-mediated upregulation of matrix metalloproteinase-9

Author keywords

Integrin linked kinase; Invasion; Lung cancer cell; Matrix metalloproteinase 9; Migration; Nuclear factor B

Indexed keywords

GELATINASE B; I KAPPA B BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTEGRIN LINKED KINASE; TRANSCRIPTION FACTOR RELA;

EID: 84879286351     PISSN: 14491907     EISSN: None     Source Type: Journal    
DOI: 10.7150/ijms.5963     Document Type: Article
Times cited : (32)

References (41)
  • 1
    • 0030026679 scopus 로고    scopus 로고
    • Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase
    • doi:10.1038/379091a0
    • Hannigan GE, Leung-Hagesteijn C, Fitz-Gibbon L, Coppolino MG, Radeva G, Filmus J, et al. Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase. Nature. 1996; 379: 91-6. doi:10.1038/379091a0.
    • (1996) Nature , vol.379 , pp. 91-96
    • Hannigan, G.E.1    Leung-Hagesteijn, C.2    Fitz-Gibbon, L.3    Coppolino, M.G.4    Radeva, G.5    Filmus, J.6
  • 2
    • 0035969233 scopus 로고    scopus 로고
    • Integrin-linked kinase (ILK) and its interactors: A new paradigm for the coupling of extracellular matrix to actin cytoskeleton and signaling complexes
    • doi:10.1083/jcb.200108077. jcb.200108077 [pii]
    • Wu C, Dedhar S. Integrin-linked kinase (ILK) and its interactors: a new paradigm for the coupling of extracellular matrix to actin cytoskeleton and signaling complexes. J Cell Biol. 2001; 155: 505-10. doi:10.1083/jcb.200108077. jcb.200108077 [pii].
    • (2001) J Cell Biol , vol.155 , pp. 505-510
    • Wu, C.1    Dedhar, S.2
  • 3
    • 33644848599 scopus 로고    scopus 로고
    • ILK, PINCH and parvin: The tIPP of integrin signalling
    • doi:nrm1789 [pii] 10.1038/nrm1789
    • Legate KR, Montanez E, Kudlacek O, Fassler R. ILK, PINCH and parvin: the tIPP of integrin signalling. Nat Rev Mol Cell Biol. 2006; 7: 20-31. doi:nrm1789 [pii] 10.1038/nrm1789.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 20-31
    • Legate, K.R.1    Montanez, E.2    Kudlacek, O.3    Fassler, R.4
  • 4
    • 0037666792 scopus 로고    scopus 로고
    • Conditional knock-out of integrin-linked kinase demonstrates an essential role in protein kinase B/Akt activation
    • doi:10.1074/jbc.M303083200 M303083200 [pii]
    • Troussard AA, Mawji NM, Ong C, Mui A, St -Arnaud R, Dedhar S. Conditional knock-out of integrin-linked kinase demonstrates an essential role in protein kinase B/Akt activation. J Biol Chem. 2003; 278: 22374-8. doi:10.1074/jbc.M303083200 M303083200 [pii].
    • (2003) J Biol Chem , vol.278 , pp. 22374-22378
    • Troussard, A.A.1    Mawji, N.M.2    Ong, C.3    Mui, A.4    Starnaud, R.5    Dedhar, S.6
  • 5
    • 11144225205 scopus 로고    scopus 로고
    • Integrin-linked kinase: A cancer therapeutic target unique among its ILK
    • doi:nrc1524 [pii] 10.1038/nrc1524
    • Hannigan G, Troussard AA, Dedhar S. Integrin-linked kinase: a cancer therapeutic target unique among its ILK. Nat Rev Cancer. 2005; 5: 51-63. doi:nrc1524 [pii] 10.1038/nrc1524.
    • (2005) Nat Rev Cancer , vol.5 , pp. 51-63
    • Hannigan, G.1    Troussard, A.A.2    Dedhar, S.3
  • 6
    • 0032530482 scopus 로고    scopus 로고
    • Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase
    • Delcommenne M, Tan C, Gray V, Rue L, Woodgett J, Dedhar S. Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase. Proc Natl Acad Sci U S A. 1998; 95: 11211-6.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 11211-11216
    • Delcommenne, M.1    Tan, C.2    Gray, V.3    Rue, L.4    Woodgett, J.5    Dedhar, S.6
  • 7
    • 0034724443 scopus 로고    scopus 로고
    • Inhibition of integrin-linked kinase (ILK) suppresses activation of protein kinase B/Akt and induces cell cycle arrest and apoptosis of PTEN-mutant prostate cancer cells
    • doi:10.1073/pnas.060579697 060579697 [pii]
    • Persad S, Attwell S, Gray V, Delcommenne M, Troussard A, Sanghera J, et al. Inhibition of integrin-linked kinase (ILK) suppresses activation of protein kinase B/Akt and induces cell cycle arrest and apoptosis of PTEN-mutant prostate cancer cells. Proc Natl Acad Sci U S A. 2000; 97: 3207-12. doi:10.1073/pnas.060579697 060579697 [pii].
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 3207-3212
    • Persad, S.1    Attwell, S.2    Gray, V.3    Delcommenne, M.4    Troussard, A.5    Sanghera, J.6
  • 8
    • 0842308778 scopus 로고    scopus 로고
    • Integrin-linked kinase (ILK) expression in human colon cancer
    • doi:10.1038/sj.bjc.6601482 6601482 [pii]
    • Bravou V, Klironomos G, Papadaki E, Stefanou D, Varakis J. Integrin-linked kinase (ILK) expression in human colon cancer. Br J Cancer. 2003; 89: 2340-1. doi:10.1038/sj.bjc.6601482 6601482 [pii].
    • (2003) Br J Cancer , vol.89 , pp. 2340-2341
    • Bravou, V.1    Klironomos, G.2    Papadaki, E.3    Stefanou, D.4    Varakis, J.5
  • 9
    • 84878558950 scopus 로고    scopus 로고
    • Overexpression of integrin-linked kinase (ILK) is associated with tumor progression and an unfavorable prognosis in patients with colorectal cancer
    • doi:10.1007/s10735-012-9463-6
    • Li R, Liu B, Yin H, Sun W, Yin J, Su Q. Overexpression of integrin-linked kinase (ILK) is associated with tumor progression and an unfavorable prognosis in patients with colorectal cancer. J Mol Histol. 2012. doi:10.1007/s10735-012-9463-6.
    • (2012) J Mol Histol
    • Li, R.1    Liu, B.2    Yin, H.3    Sun, W.4    Yin, J.5    Su, Q.6
  • 10
    • 0037295608 scopus 로고    scopus 로고
    • Expression of integrin-linked kinase is closely correlated with invasion and metastasis of gastric carcinoma
    • doi:10.1007/s00428-002-0718-6
    • Ito R, Oue N, Zhu X, Yoshida K, Nakayama H, Yokozaki H, et al. Expression of integrin-linked kinase is closely correlated with invasion and metastasis of gastric carcinoma. Virchows Arch. 2003; 442: 118-23. doi:10.1007/s00428-002-0718-6.
    • (2003) Virchows Arch , vol.442 , pp. 118-123
    • Ito, R.1    Oue, N.2    Zhu, X.3    Yoshida, K.4    Nakayama, H.5    Yokozaki, H.6
  • 12
    • 0141995796 scopus 로고    scopus 로고
    • Integrin-linked kinase expression increases with ovarian tumour grade and is sustained by peritoneal tumour fluid
    • doi:10.1002/path.1441
    • Ahmed N, Riley C, Oliva K, Stutt E, Rice GE, Quinn MA. Integrin-linked kinase expression increases with ovarian tumour grade and is sustained by peritoneal tumour fluid. J Pathol. 2003; 201: 229-37. doi:10.1002/path.1441.
    • (2003) J Pathol , vol.201 , pp. 229-237
    • Ahmed, N.1    Riley, C.2    Oliva, K.3    Stutt, E.4    Rice, G.E.5    Quinn, M.A.6
  • 13
    • 0141891463 scopus 로고    scopus 로고
    • Increased expression of integrin-linked kinase is correlated with melanoma progression and poor patient survival
    • Dai DL, Makretsov N, Campos EI, Huang C, Zhou Y, Huntsman D, et al. Increased expression of integrin-linked kinase is correlated with melanoma progression and poor patient survival. Clin Cancer Res. 2003; 9: 4409-14.
    • (2003) Clin Cancer Res , vol.9 , pp. 4409-4414
    • Dai, D.L.1    Makretsov, N.2    Campos, E.I.3    Huang, C.4    Zhou, Y.5    Huntsman, D.6
  • 14
    • 78751569979 scopus 로고    scopus 로고
    • Integrin-linked kinase, phosphorylated AKT and the prognosis of malignant pleural mesothelioma
    • doi:S1010-7940(10)00444-6 [pii] 10.1016/j.ejcts.2010.05.007
    • Watzka SB, Setinek U, Stubenberger EB, Totsch M, Dekan G, Marcher M, et al. Integrin-linked kinase, phosphorylated AKT and the prognosis of malignant pleural mesothelioma. Eur J Cardiothorac Surg. 2011; 39: 180-4. doi:S1010-7940(10)00444-6 [pii] 10.1016/j.ejcts.2010.05.007.
    • (2011) Eur J Cardiothorac Surg , vol.39 , pp. 180-184
    • Watzka, S.B.1    Setinek, U.2    Stubenberger, E.B.3    Totsch, M.4    Dekan, G.5    Marcher, M.6
  • 15
    • 13144302939 scopus 로고    scopus 로고
    • Increased expression of integrin-linked kinase is associated with shorter survival in non-small cell lung cancer
    • doi:1471-2407-5-1 [pii] 10.1186/1471-2407-5-1
    • Takanami I. Increased expression of integrin-linked kinase is associated with shorter survival in non-small cell lung cancer. BMC Cancer. 2005; 5: 1. doi:1471-2407-5-1 [pii] 10.1186/1471-2407-5-1.
    • (2005) BMC Cancer , vol.5 , pp. 1
    • Takanami, I.1
  • 16
    • 77955923601 scopus 로고    scopus 로고
    • Immunoreactivity of integrin-linked kinase in primary non-small-cell lung cancer and survival after curative resection
    • doi:S1010-7940(10)00136-3 [pii] 10.1016/j.ejcts.2010.02.006
    • Watzka SB, Rauscher-Potsch I, Stubenberger E, Getman V, Setinek U, Totsch M, et al. Immunoreactivity of integrin-linked kinase in primary non-small-cell lung cancer and survival after curative resection. Eur J Cardiothorac Surg. 2010; 38: 254-9. doi:S1010-7940(10)00136-3 [pii] 10.1016/j.ejcts.2010.02.006.
    • (2010) Eur J Cardiothorac Surg , vol.38 , pp. 254-259
    • Watzka, S.B.1    Rauscher-Potsch, I.2    Stubenberger, E.3    Getman, V.4    Setinek, U.5    Totsch, M.6
  • 17
    • 78651273473 scopus 로고    scopus 로고
    • Expression of integrin-linked kinase in lung squamous cell carcinoma and adenocarcinoma: Correlation with E-cadherin expression, tumor microvessel density and clinical outcome
    • doi:10.1007/s00428-010-1016-3
    • Yu J, Shi R, Zhang D, Wang E, Qiu X. Expression of integrin-linked kinase in lung squamous cell carcinoma and adenocarcinoma: correlation with E-cadherin expression, tumor microvessel density and clinical outcome. Virchows Arch. 2011; 458: 99-107. doi:10.1007/s00428-010-1016-3.
    • (2011) Virchows Arch , vol.458 , pp. 99-107
    • Yu, J.1    Shi, R.2    Zhang, D.3    Wang, E.4    Qiu, X.5
  • 18
    • 84860390475 scopus 로고    scopus 로고
    • MicroRNA-mediated upregulation of integrin-linked kinase promotes Src-induced tumor progression
    • doi:onc2011367 [pii] 10.1038/onc.2011.367
    • Oneyama C, Morii E, Okuzaki D, Takahashi Y, Ikeda J, Wakabayashi N, et al. MicroRNA-mediated upregulation of integrin-linked kinase promotes Src-induced tumor progression. Oncogene. 2012; 31: 1623-35. doi:onc2011367 [pii] 10.1038/onc.2011.367.
    • (2012) Oncogene , vol.31 , pp. 1623-1635
    • Oneyama, C.1    Morii, E.2    Okuzaki, D.3    Takahashi, Y.4    Ikeda, J.5    Wakabayashi, N.6
  • 19
    • 18844363699 scopus 로고    scopus 로고
    • ILK mediates actin filament rearrangements and cell migration and invasion through PI3K/Akt/Rac1 signaling
    • doi:1208525 [pii] 10.1038/sj.onc.1208525
    • Qian Y, Zhong X, Flynn DC, Zheng JZ, Qiao M, Wu C, et al. ILK mediates actin filament rearrangements and cell migration and invasion through PI3K/Akt/Rac1 signaling. Oncogene. 2005; 24: 3154-65. doi:1208525 [pii] 10.1038/sj.onc.1208525.
    • (2005) Oncogene , vol.24 , pp. 3154-3165
    • Qian, Y.1    Zhong, X.2    Flynn, D.C.3    Zheng, J.Z.4    Qiao, M.5    Wu, C.6
  • 20
    • 33745605192 scopus 로고    scopus 로고
    • Integrin-linked kinase regulates osteopontin-dependent MMP-2 and uPA expression to convey metastatic function in murine mammary epithelial cancer cells
    • doi:bgi352 [pii] 10.1093/carcin/bgi352
    • Mi Z, Guo H, Wai PY, Gao C, Kuo PC. Integrin-linked kinase regulates osteopontin-dependent MMP-2 and uPA expression to convey metastatic function in murine mammary epithelial cancer cells. Carcinogenesis. 2006; 27: 1134-45. doi:bgi352 [pii] 10.1093/carcin/bgi352.
    • (2006) Carcinogenesis , vol.27 , pp. 1134-1145
    • Mi, Z.1    Guo, H.2    Wai, P.Y.3    Gao, C.4    Kuo, P.C.5
  • 21
    • 0025847582 scopus 로고
    • Matrix metalloproteinases and their inhibitors in connective tissue remodeling
    • Woessner JF, Jr. Matrix metalloproteinases and their inhibitors in connective tissue remodeling. FASEB J. 1991; 5: 2145-54.
    • (1991) FASEB J , vol.5 , pp. 2145-2154
    • Woessner, J.F.1
  • 22
    • 0345643514 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinase expression in tumor invasion
    • Westermarck J, Kahari VM. Regulation of matrix metalloproteinase expression in tumor invasion. FASEB J. 1999; 13: 781-92.
    • (1999) FASEB J , vol.13 , pp. 781-792
    • Westermarck, J.1    Kahari, V.M.2
  • 23
    • 2442662971 scopus 로고    scopus 로고
    • Novel inhibitors of urokinase-type plasminogen activator and matrix metalloproteinase expression in metastatic cancer cell lines
    • doi:10.1002/ijc.20135
    • Cakarovski K, Leung JY, Restall C, Carin-Carlson A, Yang E, Perlmutter P, et al. Novel inhibitors of urokinase-type plasminogen activator and matrix metalloproteinase expression in metastatic cancer cell lines. Int J Cancer. 2004; 110: 610-6. doi:10.1002/ijc.20135.
    • (2004) Int J Cancer , vol.110 , pp. 610-616
    • Cakarovski, K.1    Leung, J.Y.2    Restall, C.3    Carin-Carlson, A.4    Yang, E.5    Perlmutter, P.6
  • 24
    • 34548262577 scopus 로고    scopus 로고
    • Clinical significance of MMP-2 and MMP-9 in patients with oral cancer
    • doi:10.1002/hed.20561
    • Patel BP, Shah SV, Shukla SN, Shah PM, Patel PS. Clinical significance of MMP-2 and MMP-9 in patients with oral cancer. Head Neck. 2007; 29: 564-72. doi:10.1002/hed.20561.
    • (2007) Head Neck , vol.29 , pp. 564-572
    • Patel, B.P.1    Shah, S.V.2    Shukla, S.N.3    Shah, P.M.4    Patel, P.S.5
  • 25
    • 0033760493 scopus 로고    scopus 로고
    • Overexpression of matrix metalloproteinase 2 predicts unfavorable outcome in early-stage non-small cell lung cancer
    • Passlick B, Sienel W, Seen-Hibler R, Wockel W, Thetter O, Mutschler W, et al. Overexpression of matrix metalloproteinase 2 predicts unfavorable outcome in early-stage non-small cell lung cancer. Clin Cancer Res. 2000; 6: 3944-8.
    • (2000) Clin Cancer Res , vol.6 , pp. 3944-3948
    • Passlick, B.1    Sienel, W.2    Seen-Hibler, R.3    Wockel, W.4    Thetter, O.5    Mutschler, W.6
  • 26
    • 84859059272 scopus 로고    scopus 로고
    • Downregulation of integrin-linked kinase inhibits epithelial-to-mesenchymal transition and metastasis in bladder cancer cells
    • Zhu J, Pan X, Zhang Z, Gao J, Zhang L, Chen J. Downregulation of integrin-linked kinase inhibits epithelial-to-mesenchymal transition and metastasis in bladder cancer cells. Cell Signal. 2012; 24: 1323-32.
    • (2012) Cell Signal , vol.24 , pp. 1323-1332
    • Zhu, J.1    Pan, X.2    Zhang, Z.3    Gao, J.4    Zhang, L.5    Chen, J.6
  • 27
    • 82255175153 scopus 로고    scopus 로고
    • The importance of integrin-linked kinase in the regulation of bladder cancer invasion
    • doi:10.1002/ijc.26008
    • Matsui Y, Assi K, Ogawa O, Raven PA, Dedhar S, Gleave ME, et al. The importance of integrin-linked kinase in the regulation of bladder cancer invasion. Int J Cancer. 2012; 130: 521-31. doi:10.1002/ijc.26008.
    • (2012) Int J Cancer , vol.130 , pp. 521-531
    • Matsui, Y.1    Assi, K.2    Ogawa, O.3    Raven, P.A.4    Dedhar, S.5    Gleave, M.E.6
  • 28
    • 77955172248 scopus 로고    scopus 로고
    • Inhibition of integrin-linked kinase blocks podocyte epithelial-mesenchymal transition and ameliorates proteinuria
    • doi:ki2010137 [pii] 10.1038/ki.2010.137
    • Kang YS, Li Y, Dai C, Kiss LP, Wu C, Liu Y. Inhibition of integrin-linked kinase blocks podocyte epithelial-mesenchymal transition and ameliorates proteinuria. Kidney Int. 2010; 78: 363-73. doi:ki2010137 [pii] 10.1038/ki.2010.137.
    • (2010) Kidney Int , vol.78 , pp. 363-373
    • Kang, Y.S.1    Li, Y.2    Dai, C.3    Kiss, L.P.4    Wu, C.5    Liu, Y.6
  • 29
    • 84865110910 scopus 로고    scopus 로고
    • Suppressing effect of resveratrol on the migration and invasion of human metastatic lung and cervical cancer cells
    • doi:10.1007/s11033-012-1728-3
    • Kim YS, Sull JW, Sung HJ. Suppressing effect of resveratrol on the migration and invasion of human metastatic lung and cervical cancer cells. Mol Biol Rep. 2012; 39: 8709-16. doi:10.1007/s11033-012-1728-3.
    • (2012) Mol Biol Rep , vol.39 , pp. 8709-8716
    • Kim, Y.S.1    Sull, J.W.2    Sung, H.J.3
  • 30
    • 84860511960 scopus 로고    scopus 로고
    • Osthole inhibits the invasive ability of human lung adenocarcinoma cells via suppression of NF-kappaB-mediated matrix metalloproteinase-9 expression
    • doi:S0041-008X(12)00123-8 [pii] 10.1016/j.taap.2012.03.020
    • Kao SJ, Su JL, Chen CK, Yu MC, Bai KJ, Chang JH, et al. Osthole inhibits the invasive ability of human lung adenocarcinoma cells via suppression of NF-kappaB-mediated matrix metalloproteinase-9 expression. Toxicol Appl Pharmacol. 2012; 261: 105-15. doi:S0041-008X(12)00123-8 [pii] 10.1016/j.taap.2012.03.020.
    • (2012) Toxicol Appl Pharmacol , vol.261 , pp. 105-115
    • Kao, S.J.1    Su, J.L.2    Chen, C.K.3    Yu, M.C.4    Bai, K.J.5    Chang, J.H.6
  • 31
    • 84862818300 scopus 로고    scopus 로고
    • Propofol reduces MMPs expression by inhibiting NF-kappaB activity in human MDA-MB-231 cells
    • doi:S0753-3322(11)00178-8 [pii] 10.1016/j.biopha.2011.10.006
    • Li Q, Zhang L, Han Y, Jiang Z, Wang Q. Propofol reduces MMPs expression by inhibiting NF-kappaB activity in human MDA-MB-231 cells. Biomed Pharmacother. 2012; 66: 52-6. doi:S0753-3322(11)00178-8 [pii] 10.1016/j.biopha.2011.10.006.
    • (2012) Biomed Pharmacother , vol.66 , pp. 52-56
    • Li, Q.1    Zhang, L.2    Han, Y.3    Jiang, Z.4    Wang, Q.5
  • 32
    • 79958789624 scopus 로고    scopus 로고
    • Integrin-linked kinase regulates melanoma angiogenesis by activating NF-kappaB/interleukin-6 signaling pathway
    • doi:onc2010644 [pii] 10.1038/onc.2010.644
    • Wani AA, Jafarnejad SM, Zhou J, Li G. Integrin-linked kinase regulates melanoma angiogenesis by activating NF-kappaB/interleukin-6 signaling pathway. Oncogene. 2011; 30: 2778-88. doi:onc2010644 [pii] 10.1038/onc.2010.644.
    • (2011) Oncogene , vol.30 , pp. 2778-2788
    • Wani, A.A.1    Jafarnejad, S.M.2    Zhou, J.3    Li, G.4
  • 33
    • 84872412469 scopus 로고    scopus 로고
    • Overexpression of integrin-linked kinase correlates with malignant phenotype in non-small cell lung cancer and promotes lung cancer cell invasion and migration via regulating epithelial-mesenchymal transition (EMT)-related genes
    • doi: S0065-1281(12)00076-1[pii] 10.1016/j.acthis.2012.05.004
    • Chen D, Zhang Y, Zhang X, Li J, Han B, Liu S, et al. Overexpression of integrin-linked kinase correlates with malignant phenotype in non-small cell lung cancer and promotes lung cancer cell invasion and migration via regulating epithelial-mesenchymal transition (EMT)-related genes. Acta Histochem. 2012. doi: S0065-1281(12)00076-1[pii] 10.1016/j.acthis.2012.05.004.
    • (2012) Acta Histochem
    • Chen, D.1    Zhang, Y.2    Zhang, X.3    Li, J.4    Han, B.5    Liu, S.6
  • 34
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • doi:10.1006/meth.2001.1262 S1046-2023(01)91262-9 [pii]
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods. 2001; 25: 402-8. doi:10.1006/meth.2001.1262 S1046-2023(01)91262-9 [pii].
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 35
    • 2542449068 scopus 로고    scopus 로고
    • Enhanced chemosensitivity to irinotecan by RNA interference-mediated down-regulation of the nuclear factor-kappaB p65 subunit
    • doi:10.1158/1078-0432.CCR-03-0366 10/10/3333 [pii]
    • Guo J, Verma UN, Gaynor RB, Frenkel EP, Becerra CR. Enhanced chemosensitivity to irinotecan by RNA interference-mediated down-regulation of the nuclear factor-kappaB p65 subunit. Clin Cancer Res. 2004; 10: 3333-41. doi:10.1158/1078-0432.CCR-03-0366 10/10/3333 [pii].
    • (2004) Clin Cancer Res , vol.10 , pp. 3333-3341
    • Guo, J.1    Verma, U.N.2    Gaynor, R.B.3    Frenkel, E.P.4    Becerra, C.R.5
  • 36
    • 0037051090 scopus 로고    scopus 로고
    • Inhibition of cell proliferation, invasion, tumor growth and metastasis by an oral non-antimicrobial tetracycline analog (COL-3) in a metastatic prostate cancer model
    • doi:10.1002/ijc.10168 [pii]
    • Lokeshwar BL, Selzer MG, Zhu BQ, Block NL, Golub LM. Inhibition of cell proliferation, invasion, tumor growth and metastasis by an oral non-antimicrobial tetracycline analog (COL-3) in a metastatic prostate cancer model. Int J Cancer. 2002; 98: 297-309. doi:10.1002/ijc.10168 [pii].
    • (2002) Int J Cancer , vol.98 , pp. 297-309
    • Lokeshwar, B.L.1    Selzer, M.G.2    Zhu, B.Q.3    Block, N.L.4    Golub, L.M.5
  • 38
    • 0141720342 scopus 로고    scopus 로고
    • Role for integrin-linked kinase in mediating tubular epithelial to mesenchymal transition and renal interstitial fibrogenesis
    • doi:10.1172/JCI17913 112/4/503 [pii]
    • Li Y, Yang J, Dai C, Wu C, Liu Y. Role for integrin-linked kinase in mediating tubular epithelial to mesenchymal transition and renal interstitial fibrogenesis. J Clin Invest. 2003; 112: 503-16. doi:10.1172/JCI17913 112/4/503 [pii].
    • (2003) J Clin Invest , vol.112 , pp. 503-516
    • Li, Y.1    Yang, J.2    Dai, C.3    Wu, C.4    Liu, Y.5
  • 39
    • 0035137882 scopus 로고    scopus 로고
    • Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB
    • doi:10.1172/JCI11991
    • Baldwin AS. Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB. J Clin Invest. 2001; 107: 241-6. doi:10.1172/JCI11991.
    • (2001) J Clin Invest , vol.107 , pp. 241-246
    • Baldwin, A.S.1
  • 40
    • 78751571123 scopus 로고    scopus 로고
    • Culture of human breast cancer cell line (MDA-MB-231) on fibronectin-coated surface induces pro-matrix metalloproteinase-9 expression and activity
    • doi:10.1007/s13277-010-0106-9
    • Maity G, Choudhury PR, Sen T, Ganguly KK, Sil H, Chatterjee A. Culture of human breast cancer cell line (MDA-MB-231) on fibronectin-coated surface induces pro-matrix metalloproteinase-9 expression and activity. Tumour Biol. 2011; 32: 129-38. doi:10.1007/s13277-010-0106-9.
    • (2011) Tumour Biol , vol.32 , pp. 129-138
    • Maity, G.1    Choudhury, P.R.2    Sen, T.3    Ganguly, K.K.4    Sil, H.5    Chatterjee, A.6
  • 41
    • 78650878363 scopus 로고    scopus 로고
    • NF-kappaB, inflammation, and metabolic disease
    • doi:S1550-4131(10)00450-X [pii] 10.1016/j.cmet.2010.12.008
    • Baker RG, Hayden MS, Ghosh S. NF-kappaB, inflammation, and metabolic disease. Cell Metab. 2011; 13: 11-22. doi:S1550-4131(10)00450-X [pii] 10.1016/j.cmet.2010.12.008
    • (2011) Cell Metab , vol.13 , pp. 11-22
    • Baker, R.G.1    Hayden, M.S.2    Ghosh, S.3


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