Overexpression of integrin-linked kinase correlates with malignant phenotype in non-small cell lung cancer and promotes lung cancer cell invasion and migration via regulating epithelial-mesenchymal transition (EMT)-related genes

Acta Histochemica

Volumn 115, Issue 2, 2013, Pages 128-136

  Chen, Donghong ^a   Zhang, Yibing ^b   Zhang, Xuhua ^a   Li, Jing ^a   Han, Bing ^a   Liu, Shuo ^a   Wang, Lingling ^a   Ling, Yuan ^a   Mao, Shitao ^a   Wang, Xiaoge ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b GENERAL HOSPITAL OF NORTHERN THEATER COMMAND   (China)

Author keywords

Epithelial mesenchymal transition; Integrin linked kinase; Invasion; Lung cancer; Migration; Nuclear factor B

Indexed keywords

COMPLEMENTARY DNA; FIBRONECTIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTEGRIN LINKED KINASE; MESSENGER RNA; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTOR SLUG; TRANSCRIPTION FACTOR SNAIL; UVOMORULIN; VIMENTIN;

ADULT; AGED; ARTICLE; CANCER CELL CULTURE; CANCER INVASION; CANCER STAGING; CELL MIGRATION; CELL STRUCTURE; DOWN REGULATION; ENZYME PHOSPHORYLATION; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LUNG CANCER; LUNG NON SMALL CELL CANCER; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; MALIGNANT NEOPLASTIC DISEASE; MONOLAYER CULTURE; PHENOTYPE; PHENOTYPIC VARIATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SMOKING; TUMOR CLASSIFICATION; TUMOR DIFFERENTIATION; UPREGULATION;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; CELL MOVEMENT; COLLAGEN; DRUG COMBINATIONS; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LAMININ; LUNG NEOPLASMS; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; NF-KAPPA B; PHENOTYPE; PLASMIDS; PROTEIN-SERINE-THREONINE KINASES; PROTEOGLYCANS; WOUND HEALING;

GASTROPODA;

EID: 84872412469     PISSN: 00651281     EISSN: 16180372     Source Type: Journal    
DOI: 10.1016/j.acthis.2012.05.004     Document Type: Article

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