The intrinsic stability of the human prion β-sheet region investigated by molecular dynamics

Journal of Biomolecular Structure and Dynamics

Volumn 31, Issue 5, 2013, Pages 441-452

  De Simonea, Alfonso ^a   Stanzione, Francesca ^b   Marasco, Daniela ^c   Vitagliano, Luigi ^b   Esposito, Luciana ^b  

^a Division of Molecular Biosciences   (United Kingdom)

^b CNR   (Italy)

^c UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Computer simulations; Neurodegenerative diseases; Prion peptide stability; Prion toxicity

Indexed keywords

PRION PROTEIN;

ARTICLE; BETA SHEET; CARBOXY TERMINAL SEQUENCE; COMPUTER SIMULATION; CYTOTOXICITY; DEGENERATIVE DISEASE; DIMERIZATION; HOMOZYGOSITY; HUMAN; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; POINT MUTATION; PRION DISEASE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STABILITY; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; HUMANS; HYDROGEN BONDING; MOLECULAR DYNAMICS SIMULATION; MUTATION, MISSENSE; PRIONS; PROTEIN STABILITY; PROTEIN STRUCTURE, SECONDARY; THERMODYNAMICS;

EID: 84879195454     PISSN: 07391102     EISSN: 15380254     Source Type: Journal    
DOI: 10.1080/07391102.2012.703070     Document Type: Article

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