Diverse effects on the native β-sheet of the human prion protein due to disease-associated mutations

Biochemistry

Volumn 49, Issue 45, 2010, Pages 9874-9881

  Chen, Wei ^a   Van Der Kamp, Marc W ^a   Daggett, Valerie ^a  

^a University of Washington   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIFFERENT EFFECTS; DYNAMIC EFFECTS; GENETIC MUTATIONS; HUMAN PRION PROTEIN; MISFOLDING; NEURODEGENERATIVE DISORDERS; POINT MUTATIONS; PRION DISEASE; PRION PROTEIN; SIDE CHAINS; SIDE-CHAIN INTERACTIONS; WILD TYPES;

SCANDIUM;

MOLECULAR DYNAMICS;

PRION PROTEIN;

ARTICLE; BETA SHEET; DISEASE ASSOCIATION; GENE MUTATION; HUMAN; MOLECULAR DYNAMICS; MUTATIONAL ANALYSIS; POINT MUTATION; PRION DISEASE; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN INTERACTION; WILD TYPE;

AMINO ACID SEQUENCE; COMPUTER SIMULATION; HUMANS; HYDROGEN BONDING; MODELS, MOLECULAR; MUTATION; PRION DISEASES; PRIONS; PROTEIN CONFORMATION; PROTEIN FOLDING; PRPC PROTEINS;

EID: 78149436073     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi101449f     Document Type: Article

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