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Volumn 8, Issue 6, 2013, Pages

Adaptive Induction of Growth Differentiation Factor 15 Attenuates Endothelial Cell Apoptosis in Response to High Glucose Stimulus

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUCOSE; GROWTH DIFFERENTIATION FACTOR 15; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE;

EID: 84879057716     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0065549     Document Type: Article
Times cited : (89)

References (53)
  • 1
    • 12644256640 scopus 로고    scopus 로고
    • MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-beta superfamily
    • Bootcov MR, Bauskin AR, Valenzuela SM, Moore AG, Bansal M, et al. (1997) MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-beta superfamily. Proc Natl Acad Sci U S A 94: 11514-11519.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 11514-11519
    • Bootcov, M.R.1    Bauskin, A.R.2    Valenzuela, S.M.3    Moore, A.G.4    Bansal, M.5
  • 2
    • 84865421888 scopus 로고    scopus 로고
    • Macrophage inhibitory cytokine-1 (MIC-1/GDF15) slows cancer development but increases metastases in TRAMP prostate cancer prone mice
    • Husaini Y, Qiu MR, Lockwood GP, Luo XW, Shang P, et al. (2012) Macrophage inhibitory cytokine-1 (MIC-1/GDF15) slows cancer development but increases metastases in TRAMP prostate cancer prone mice. PLoS One 7: e43833.
    • (2012) PLoS One , vol.7
    • Husaini, Y.1    Qiu, M.R.2    Lockwood, G.P.3    Luo, X.W.4    Shang, P.5
  • 3
    • 0030716303 scopus 로고    scopus 로고
    • Identification of a novel member of the TGF-beta superfamily highly expressed in human placenta
    • Lawton LN, Bonaldo MF, Jelenc PC, Qiu L, Baumes SA, et al. (1997) Identification of a novel member of the TGF-beta superfamily highly expressed in human placenta. Gene 203: 17-26.
    • (1997) Gene , vol.203 , pp. 17-26
    • Lawton, L.N.1    Bonaldo, M.F.2    Jelenc, P.C.3    Qiu, L.4    Baumes, S.A.5
  • 4
    • 0030795033 scopus 로고    scopus 로고
    • Human cDNA encoding a novel TGF-beta superfamily protein highly expressed in placenta
    • Yokoyama-Kobayashi M, Saeki M, Sekine S, Kato S, (1997) Human cDNA encoding a novel TGF-beta superfamily protein highly expressed in placenta. J Biochem 122: 622-626.
    • (1997) J Biochem , vol.122 , pp. 622-626
    • Yokoyama-Kobayashi, M.1    Saeki, M.2    Sekine, S.3    Kato, S.4
  • 5
    • 0034602650 scopus 로고    scopus 로고
    • PTGF-beta, a type beta transforming growth factor (TGF-beta) superfamily member, is a p53 target gene that inhibits tumor cell growth via TGF-beta signaling pathway
    • Tan M, Wang Y, Guan K, Sun Y, (2000) PTGF-beta, a type beta transforming growth factor (TGF-beta) superfamily member, is a p53 target gene that inhibits tumor cell growth via TGF-beta signaling pathway. Proc Natl Acad Sci U S A 97: 109-114.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 109-114
    • Tan, M.1    Wang, Y.2    Guan, K.3    Sun, Y.4
  • 6
    • 15144351714 scopus 로고    scopus 로고
    • Cloning and characterization of a novel member of the transforming growth factor-beta/bone morphogenetic protein family
    • Paralkar VM, Vail AL, Grasser WA, Brown TA, Xu H, et al. (1998) Cloning and characterization of a novel member of the transforming growth factor-beta/bone morphogenetic protein family. J Biol Chem 273: 13760-13767.
    • (1998) J Biol Chem , vol.273 , pp. 13760-13767
    • Paralkar, V.M.1    Vail, A.L.2    Grasser, W.A.3    Brown, T.A.4    Xu, H.5
  • 8
    • 65549126847 scopus 로고    scopus 로고
    • PLAB induction in fenretinide-induced apoptosis of ovarian cancer cells occurs via a ROS-dependent mechanism involving ER stress and JNK activation
    • Appierto V, Tiberio P, Villani MG, Cavadini E, Formelli F, (2009) PLAB induction in fenretinide-induced apoptosis of ovarian cancer cells occurs via a ROS-dependent mechanism involving ER stress and JNK activation. Carcinogenesis 30: 824-831.
    • (2009) Carcinogenesis , vol.30 , pp. 824-831
    • Appierto, V.1    Tiberio, P.2    Villani, M.G.3    Cavadini, E.4    Formelli, F.5
  • 9
    • 10644274362 scopus 로고    scopus 로고
    • 15-Hydroxyprostaglandin dehydrogenase, a COX-2 oncogene antagonist, is a TGF-beta-induced suppressor of human gastrointestinal cancers
    • Yan M, Rerko RM, Platzer P, Dawson D, Willis J, et al. (2004) 15-Hydroxyprostaglandin dehydrogenase, a COX-2 oncogene antagonist, is a TGF-beta-induced suppressor of human gastrointestinal cancers. Proc Natl Acad Sci U S A 101: 17468-17473.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 17468-17473
    • Yan, M.1    Rerko, R.M.2    Platzer, P.3    Dawson, D.4    Willis, J.5
  • 10
    • 31644433902 scopus 로고    scopus 로고
    • Changes in gene expression contribute to cancer prevention by COX inhibitors
    • Baek SJ, Eling TE, (2006) Changes in gene expression contribute to cancer prevention by COX inhibitors. Prog Lipid Res 45: 1-16.
    • (2006) Prog Lipid Res , vol.45 , pp. 1-16
    • Baek, S.J.1    Eling, T.E.2
  • 11
    • 18844398312 scopus 로고    scopus 로고
    • PL74, a novel member of the transforming growth factor-beta superfamily, is overexpressed in preeclampsia and causes apoptosis in trophoblast cells
    • Li H, Dakour J, Guilbert LJ, Winkler-Lowen B, Lyall F, et al. (2005) PL74, a novel member of the transforming growth factor-beta superfamily, is overexpressed in preeclampsia and causes apoptosis in trophoblast cells. J Clin Endocrinol Metab 90: 3045-3053.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 3045-3053
    • Li, H.1    Dakour, J.2    Guilbert, L.J.3    Winkler-Lowen, B.4    Lyall, F.5
  • 12
    • 33646795684 scopus 로고    scopus 로고
    • GDF15, a cardioprotective TGF-beta superfamily protein
    • Ago T, Sadoshima J, (2006) GDF15, a cardioprotective TGF-beta superfamily protein. Circ Res 98: 294-297.
    • (2006) Circ Res , vol.98 , pp. 294-297
    • Ago, T.1    Sadoshima, J.2
  • 13
    • 33744960940 scopus 로고    scopus 로고
    • Role of macrophage inhibitory cytokine-1 in tumorigenesis and diagnosis of cancer
    • Bauskin AR, Brown DA, Kuffner T, Johnen H, Luo XW, et al. (2006) Role of macrophage inhibitory cytokine-1 in tumorigenesis and diagnosis of cancer. Cancer Res 66: 4983-4986.
    • (2006) Cancer Res , vol.66 , pp. 4983-4986
    • Bauskin, A.R.1    Brown, D.A.2    Kuffner, T.3    Johnen, H.4    Luo, X.W.5
  • 14
    • 33646076691 scopus 로고    scopus 로고
    • The transforming growth factor-beta superfamily member growth-differentiation factor-15 protects the heart from ischemia/reperfusion injury
    • Kempf T, Eden M, Strelau J, Naguib M, Willenbockel C, et al. (2006) The transforming growth factor-beta superfamily member growth-differentiation factor-15 protects the heart from ischemia/reperfusion injury. Circ Res 98: 351-360.
    • (2006) Circ Res , vol.98 , pp. 351-360
    • Kempf, T.1    Eden, M.2    Strelau, J.3    Naguib, M.4    Willenbockel, C.5
  • 15
    • 33646076196 scopus 로고    scopus 로고
    • GDF15/MIC-1 functions as a protective and antihypertrophic factor released from the myocardium in association with SMAD protein activation
    • Xu J, Kimball TR, Lorenz JN, Brown DA, Bauskin AR, et al. (2006) GDF15/MIC-1 functions as a protective and antihypertrophic factor released from the myocardium in association with SMAD protein activation. Circ Res 98: 342-350.
    • (2006) Circ Res , vol.98 , pp. 342-350
    • Xu, J.1    Kimball, T.R.2    Lorenz, J.N.3    Brown, D.A.4    Bauskin, A.R.5
  • 16
    • 77954377464 scopus 로고    scopus 로고
    • Biomarkers in acute myocardial infarction
    • Chan D, Ng LL, (2010) Biomarkers in acute myocardial infarction. BMC Med 8: 34.
    • (2010) BMC Med , vol.8 , pp. 34
    • Chan, D.1    Ng, L.L.2
  • 17
    • 0037157611 scopus 로고    scopus 로고
    • Concentration in plasma of macrophage inhibitory cytokine-1 and risk of cardiovascular events in women: a nested case-control study
    • Brown DA, Breit SN, Buring J, Fairlie WD, Bauskin AR, et al. (2002) Concentration in plasma of macrophage inhibitory cytokine-1 and risk of cardiovascular events in women: a nested case-control study. Lancet 359: 2159-2163.
    • (2002) Lancet , vol.359 , pp. 2159-2163
    • Brown, D.A.1    Breit, S.N.2    Buring, J.3    Fairlie, W.D.4    Bauskin, A.R.5
  • 18
    • 77952522577 scopus 로고    scopus 로고
    • Growth differentiation factor 15 acts anti-apoptotic and pro-hypertrophic in adult cardiomyocytes
    • Heger J, Schiegnitz E, von Waldthausen D, Anwar MM, Piper HM, et al. (2010) Growth differentiation factor 15 acts anti-apoptotic and pro-hypertrophic in adult cardiomyocytes. J Cell Physiol 224: 120-126.
    • (2010) J Cell Physiol , vol.224 , pp. 120-126
    • Heger, J.1    Schiegnitz, E.2    von Waldthausen, D.3    Anwar, M.M.4    Piper, H.M.5
  • 19
    • 79955668213 scopus 로고    scopus 로고
    • GDF-15 is abundantly expressed in plexiform lesions in patients with pulmonary arterial hypertension and affects proliferation and apoptosis of pulmonary endothelial cells
    • Nickel N, Jonigk D, Kempf T, Bockmeyer CL, Maegel L, et al. (2011) GDF-15 is abundantly expressed in plexiform lesions in patients with pulmonary arterial hypertension and affects proliferation and apoptosis of pulmonary endothelial cells. Respir Res 12: 62.
    • (2011) Respir Res , vol.12 , pp. 62
    • Nickel, N.1    Jonigk, D.2    Kempf, T.3    Bockmeyer, C.L.4    Maegel, L.5
  • 20
    • 84866239730 scopus 로고    scopus 로고
    • Hyperglycemia and endothelial dysfunction in atherosclerosis: lessons from type 1 diabetes
    • Funk SD, Yurdagul A Jr, Orr AW, (2012) Hyperglycemia and endothelial dysfunction in atherosclerosis: lessons from type 1 diabetes. Int J Vasc Med 2012: 569654.
    • (2012) Int J Vasc Med , vol.2012 , pp. 569654
    • Funk, S.D.1    Yurdagul Jr., A.2    Orr, A.W.3
  • 22
    • 0034634281 scopus 로고    scopus 로고
    • Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress
    • Cai H, Harrison DG, (2000) Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ Res 87: 840-844.
    • (2000) Circ Res , vol.87 , pp. 840-844
    • Cai, H.1    Harrison, D.G.2
  • 23
    • 79953763364 scopus 로고    scopus 로고
    • Signaling of reactive oxygen and nitrogen species in Diabetes mellitus
    • Afanas'ev I, (2010) Signaling of reactive oxygen and nitrogen species in Diabetes mellitus. Oxid Med Cell Longev 3: 361-373.
    • (2010) Oxid Med Cell Longev , vol.3 , pp. 361-373
    • Afanas'ev, I.1
  • 24
    • 38149142583 scopus 로고    scopus 로고
    • Endothelial dysfunction in diabetes mellitus
    • Hadi HA, Suwaidi JA, (2007) Endothelial dysfunction in diabetes mellitus. Vasc Health Risk Manag 3: 853-876.
    • (2007) Vasc Health Risk Manag , vol.3 , pp. 853-876
    • Hadi, H.A.1    Suwaidi, J.A.2
  • 25
    • 27844593740 scopus 로고    scopus 로고
    • High glucose-induced apoptosis in human vascular endothelial cells is mediated through NF-kappaB and c-Jun NH2-terminal kinase pathway and prevented by PI3K/Akt/eNOS pathway
    • Ho FM, Lin WW, Chen BC, Chao CM, Yang CR, et al. (2006) High glucose-induced apoptosis in human vascular endothelial cells is mediated through NF-kappaB and c-Jun NH2-terminal kinase pathway and prevented by PI3K/Akt/eNOS pathway. Cell Signal 18: 391-399.
    • (2006) Cell Signal , vol.18 , pp. 391-399
    • Ho, F.M.1    Lin, W.W.2    Chen, B.C.3    Chao, C.M.4    Yang, C.R.5
  • 26
    • 0344850195 scopus 로고    scopus 로고
    • Generation of reactive oxygen intermediates, activation of NF-kappaB, and induction of apoptosis in human endothelial cells by glucose: role of nitric oxide synthase?
    • Du X, Stocklauser-Färber K, Rösen P, (1999) Generation of reactive oxygen intermediates, activation of NF-kappaB, and induction of apoptosis in human endothelial cells by glucose: role of nitric oxide synthase? Free Radic Biol Med 27: 752-763.
    • (1999) Free Radic Biol Med , vol.27 , pp. 752-763
    • Du, X.1    Stocklauser-Färber, K.2    Rösen, P.3
  • 27
    • 0034612261 scopus 로고    scopus 로고
    • High glucose-induced apoptosis in human endothelial cells is mediated by sequential activations of c-Jun NH(2)-terminal kinase and caspase-3
    • Ho FM, Liu SH, Liau CS, Huang PJ, Lin-Shiau SY, (2000) High glucose-induced apoptosis in human endothelial cells is mediated by sequential activations of c-Jun NH(2)-terminal kinase and caspase-3. Circulation 101: 2618-2624.
    • (2000) Circulation , vol.101 , pp. 2618-2624
    • Ho, F.M.1    Liu, S.H.2    Liau, C.S.3    Huang, P.J.4    Lin-Shiau, S.Y.5
  • 28
    • 0036095269 scopus 로고    scopus 로고
    • Hyperglycemia-induced apoptosis in human umbilical vein endothelial cells: inhibition by the AMP-activated protein kinase activation
    • Ido Y, Carling D, Ruderman N, (2002) Hyperglycemia-induced apoptosis in human umbilical vein endothelial cells: inhibition by the AMP-activated protein kinase activation. Diabetes 51: 159-167.
    • (2002) Diabetes , vol.51 , pp. 159-167
    • Ido, Y.1    Carling, D.2    Ruderman, N.3
  • 29
    • 33744473330 scopus 로고    scopus 로고
    • Constant and intermittent high glucose enhances endothelial cell apoptosis through mitochondrial superoxide overproduction
    • Piconi L, Quagliaro L, Assaloni R, Da Ros R, Maier A, et al. (2006) Constant and intermittent high glucose enhances endothelial cell apoptosis through mitochondrial superoxide overproduction. Diabetes Metab Res Rev 22: 198-203.
    • (2006) Diabetes Metab Res Rev , vol.22 , pp. 198-203
    • Piconi, L.1    Quagliaro, L.2    Assaloni, R.3    Da Ros, R.4    Maier, A.5
  • 30
    • 14644425394 scopus 로고    scopus 로고
    • High glucose induces human endothelial cell apoptosis through a phosphoinositide 3-kinase-regulated cyclooxygenase-2 pathway
    • Sheu ML, Ho FM, Yang RS, Chao KF, Lin WW, et al. (2005) High glucose induces human endothelial cell apoptosis through a phosphoinositide 3-kinase-regulated cyclooxygenase-2 pathway. Arterioscler Thromb Vasc Biol 25: 539-545.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 539-545
    • Sheu, M.L.1    Ho, F.M.2    Yang, R.S.3    Chao, K.F.4    Lin, W.W.5
  • 31
    • 38649101592 scopus 로고    scopus 로고
    • Inhibitory effects of fenofibrate on apoptosis and cell proliferation in human endothelial cells in high glucose
    • Zanetti M, Stocca A, Dapas B, Farra R, Uxa L, et al. (2008) Inhibitory effects of fenofibrate on apoptosis and cell proliferation in human endothelial cells in high glucose. J Mol Med (Berl) 86: 185-195.
    • (2008) J Mol Med (Berl) , vol.86 , pp. 185-195
    • Zanetti, M.1    Stocca, A.2    Dapas, B.3    Farra, R.4    Uxa, L.5
  • 33
    • 33748308777 scopus 로고    scopus 로고
    • Apoptosis signal-regulating kinase 1 mediates cellular senescence induced by high glucose in endothelial cells
    • Yokoi T, Fukuo K, Yasuda O, Hotta M, Miyazaki J, et al. (2006) Apoptosis signal-regulating kinase 1 mediates cellular senescence induced by high glucose in endothelial cells. Diabetes 55: 1660-1665.
    • (2006) Diabetes , vol.55 , pp. 1660-1665
    • Yokoi, T.1    Fukuo, K.2    Yasuda, O.3    Hotta, M.4    Miyazaki, J.5
  • 34
    • 79956216700 scopus 로고    scopus 로고
    • Dose-dependent modulatory effects of insulin on glucose-induced endothelial senescence in vitro and in vivo: a relationship between telomeres and nitric oxide
    • Matsui-Hirai H, Hayashi T, Yamamoto S, Ina K, Maeda M, et al. (2011) Dose-dependent modulatory effects of insulin on glucose-induced endothelial senescence in vitro and in vivo: a relationship between telomeres and nitric oxide. J Pharmacol Exp Ther 337: 591-599.
    • (2011) J Pharmacol Exp Ther , vol.337 , pp. 591-599
    • Matsui-Hirai, H.1    Hayashi, T.2    Yamamoto, S.3    Ina, K.4    Maeda, M.5
  • 36
    • 34548042300 scopus 로고    scopus 로고
    • Growth-differentiation factor-15 in cardiovascular disease: from bench to bedside, and back
    • Wollert KC, (2007) Growth-differentiation factor-15 in cardiovascular disease: from bench to bedside, and back. Basic Res Cardiol 102: 412-415.
    • (2007) Basic Res Cardiol , vol.102 , pp. 412-415
    • Wollert, K.C.1
  • 37
    • 35748983833 scopus 로고    scopus 로고
    • High glucose attenuates protein S-nitrosylation in endothelial cells: role of oxidative stress
    • Wadham C, Parker A, Wang L, Xia P, (2007) High glucose attenuates protein S-nitrosylation in endothelial cells: role of oxidative stress. Diabetes 56: 2715-2721.
    • (2007) Diabetes , vol.56 , pp. 2715-2721
    • Wadham, C.1    Parker, A.2    Wang, L.3    Xia, P.4
  • 38
    • 61849084730 scopus 로고    scopus 로고
    • p53 controls prostate-derived factor/macrophage inhibitory cytokine/NSAID-activated gene expression in response to cell density, DNA damage and hypoxia through diverse mechanisms
    • Kelly JA, Lucia MS, Lambert JR, (2009) p53 controls prostate-derived factor/macrophage inhibitory cytokine/NSAID-activated gene expression in response to cell density, DNA damage and hypoxia through diverse mechanisms. Cancer Lett 277: 38-47.
    • (2009) Cancer Lett , vol.277 , pp. 38-47
    • Kelly, J.A.1    Lucia, M.S.2    Lambert, J.R.3
  • 39
    • 67649440675 scopus 로고    scopus 로고
    • The antioxidant effects of quercetin metabolites on the prevention of high glucose-induced apoptosis of human umbilical vein endothelial cells
    • Chao CL, Hou YC, Chao PD, Weng CS, Ho FM, (2009) The antioxidant effects of quercetin metabolites on the prevention of high glucose-induced apoptosis of human umbilical vein endothelial cells. Br J Nutr 101: 1165-1170.
    • (2009) Br J Nutr , vol.101 , pp. 1165-1170
    • Chao, C.L.1    Hou, Y.C.2    Chao, P.D.3    Weng, C.S.4    Ho, F.M.5
  • 40
    • 70349254617 scopus 로고    scopus 로고
    • Increased serum concentrations of macrophage inhibitory cytokine-1 in patients with obesity and type 2 diabetes mellitus: the influence of very low calorie diet
    • Dostálová I, Roubícek T, Bártlová M, Mráz M, Lacinová Z, et al. (2009) Increased serum concentrations of macrophage inhibitory cytokine-1 in patients with obesity and type 2 diabetes mellitus: the influence of very low calorie diet. Eur J Endocrinol 161: 397-404.
    • (2009) Eur J Endocrinol , vol.161 , pp. 397-404
    • Dostálová, I.1    Roubícek, T.2    Bártlová, M.3    Mráz, M.4    Lacinová, Z.5
  • 41
    • 84859733519 scopus 로고    scopus 로고
    • Macrophage inhibitory cytokine 1 (MIC-1/GDF15) decreases food intake, body weight and improves glucose tolerance in mice on normal & obesogenic diets
    • Macia L, Tsai VW, Nguyen AD, Johnen H, Kuffner T, et al. (2012) Macrophage inhibitory cytokine 1 (MIC-1/GDF15) decreases food intake, body weight and improves glucose tolerance in mice on normal & obesogenic diets. PLoS One 7: e34868.
    • (2012) PLoS One , vol.7
    • Macia, L.1    Tsai, V.W.2    Nguyen, A.D.3    Johnen, H.4    Kuffner, T.5
  • 42
    • 79953889861 scopus 로고    scopus 로고
    • The effect of very-low-calorie diet on mRNA expression of inflammation-related genes in subcutaneous adipose tissue and peripheral monocytes of obese patients with type 2 diabetes mellitus
    • Mraz M, Lacinova Z, Drapalova J, Haluzikova D, Horinek A, et al. (2011) The effect of very-low-calorie diet on mRNA expression of inflammation-related genes in subcutaneous adipose tissue and peripheral monocytes of obese patients with type 2 diabetes mellitus. J Clin Endocrinol Metab 96: E606-613.
    • (2011) J Clin Endocrinol Metab , vol.96
    • Mraz, M.1    Lacinova, Z.2    Drapalova, J.3    Haluzikova, D.4    Horinek, A.5
  • 43
    • 0037142612 scopus 로고    scopus 로고
    • Anoxia induces macrophage inhibitory cytokine-1 (MIC-1) in glioblastoma cells independently of p53 and HIF-1
    • Albertoni M, Shaw PH, Nozaki M, Godard S, Tenan M, et al. (2002) Anoxia induces macrophage inhibitory cytokine-1 (MIC-1) in glioblastoma cells independently of p53 and HIF-1. Oncogene 21: 4212-4219.
    • (2002) Oncogene , vol.21 , pp. 4212-4219
    • Albertoni, M.1    Shaw, P.H.2    Nozaki, M.3    Godard, S.4    Tenan, M.5
  • 44
    • 0035060429 scopus 로고    scopus 로고
    • Cyclooxygenase inhibitors regulate the expression of a TGF-beta superfamily member that has proapoptotic and antitumorigenic activities
    • Baek SJ, Kim KS, Nixon JB, Wilson LC, Eling TE, (2001) Cyclooxygenase inhibitors regulate the expression of a TGF-beta superfamily member that has proapoptotic and antitumorigenic activities. Mol Pharmacol 59: 901-908.
    • (2001) Mol Pharmacol , vol.59 , pp. 901-908
    • Baek, S.J.1    Kim, K.S.2    Nixon, J.B.3    Wilson, L.C.4    Eling, T.E.5
  • 45
    • 0043016358 scopus 로고    scopus 로고
    • Macrophage inhibitory cytokine 1 reduces cell adhesion and induces apoptosis in prostate cancer cells
    • Liu T, Bauskin AR, Zaunders J, Brown DA, Pankhurst S, et al. (2003) Macrophage inhibitory cytokine 1 reduces cell adhesion and induces apoptosis in prostate cancer cells. Cancer Res 63: 5034-5040.
    • (2003) Cancer Res , vol.63 , pp. 5034-5040
    • Liu, T.1    Bauskin, A.R.2    Zaunders, J.3    Brown, D.A.4    Pankhurst, S.5
  • 46
    • 15944422900 scopus 로고    scopus 로고
    • The conventional nonsteroidal anti-inflammatory drug sulindac sulfide arrests ovarian cancer cell growth via the expression of NAG-1/MIC-1/GDF-15
    • Kim JS, Baek SJ, Sali T, Eling TE, (2005) The conventional nonsteroidal anti-inflammatory drug sulindac sulfide arrests ovarian cancer cell growth via the expression of NAG-1/MIC-1/GDF-15. Mol Cancer Ther 4: 487-493.
    • (2005) Mol Cancer Ther , vol.4 , pp. 487-493
    • Kim, J.S.1    Baek, S.J.2    Sali, T.3    Eling, T.E.4
  • 47
    • 34247623111 scopus 로고    scopus 로고
    • Celecoxib induces apoptosis in COX-2 deficient human gastric cancer cells through Akt/GSK3beta/NAG-1 pathway
    • Pang RP, Zhou JG, Zeng ZR, Li XY, Chen W, et al. (2007) Celecoxib induces apoptosis in COX-2 deficient human gastric cancer cells through Akt/GSK3beta/NAG-1 pathway. Cancer Lett 251: 268-277.
    • (2007) Cancer Lett , vol.251 , pp. 268-277
    • Pang, R.P.1    Zhou, J.G.2    Zeng, Z.R.3    Li, X.Y.4    Chen, W.5
  • 48
    • 12844260806 scopus 로고    scopus 로고
    • Indole-3-carbinol and 3,3′-diindolylmethane induce expression of NAG-1 in a p53-independent manner
    • Lee SH, Kim JS, Yamaguchi K, Eling TE, Baek SJ, (2005) Indole-3-carbinol and 3,3′-diindolylmethane induce expression of NAG-1 in a p53-independent manner. Biochem Biophys Res Commun 328: 63-69.
    • (2005) Biochem Biophys Res Commun , vol.328 , pp. 63-69
    • Lee, S.H.1    Kim, J.S.2    Yamaguchi, K.3    Eling, T.E.4    Baek, S.J.5
  • 49
    • 41849104687 scopus 로고    scopus 로고
    • Macrophage inhibitory cytokine-1 activates AKT and ERK-1/2 via the transactivation of ErbB2 in human breast and gastric cancer cells
    • Kim KK, Lee JJ, Yang Y, You KH, Lee JH, (2008) Macrophage inhibitory cytokine-1 activates AKT and ERK-1/2 via the transactivation of ErbB2 in human breast and gastric cancer cells. Carcinogenesis 29: 704-712.
    • (2008) Carcinogenesis , vol.29 , pp. 704-712
    • Kim, K.K.1    Lee, J.J.2    Yang, Y.3    You, K.H.4    Lee, J.H.5
  • 50
    • 67549138951 scopus 로고    scopus 로고
    • Expression of growth differentiation factor 15 is positively correlated with histopathological malignant grade and in vitro cell proliferation in oral squamous cell carcinoma
    • Zhang L, Yang X, Pan HY, Zhou XJ, Li J, et al. (2009) Expression of growth differentiation factor 15 is positively correlated with histopathological malignant grade and in vitro cell proliferation in oral squamous cell carcinoma. Oral Oncol 45: 627-632.
    • (2009) Oral Oncol , vol.45 , pp. 627-632
    • Zhang, L.1    Yang, X.2    Pan, H.Y.3    Zhou, X.J.4    Li, J.5
  • 51
    • 77949267633 scopus 로고    scopus 로고
    • Overexpression of macrophage inhibitory cytokine-1 induces metastasis of human prostate cancer cells through the FAK-RhoA signaling pathway
    • Senapati S, Rachagani S, Chaudhary K, Johansson SL, Singh RK, et al. (2010) Overexpression of macrophage inhibitory cytokine-1 induces metastasis of human prostate cancer cells through the FAK-RhoA signaling pathway. Oncogene 29: 1293-1302.
    • (2010) Oncogene , vol.29 , pp. 1293-1302
    • Senapati, S.1    Rachagani, S.2    Chaudhary, K.3    Johansson, S.L.4    Singh, R.K.5
  • 52
    • 70350398634 scopus 로고    scopus 로고
    • Growth/differentiation factor-15 inhibits differentiation into osteoclasts-a novel factor involved in control of osteoclast differentiation
    • Vanhara P, Lincová E, Kozubík A, Jurdic P, Soucek K, et al. (2009) Growth/differentiation factor-15 inhibits differentiation into osteoclasts-a novel factor involved in control of osteoclast differentiation. Differentiation 78: 213-222.
    • (2009) Differentiation , vol.78 , pp. 213-222
    • Vanhara, P.1    Lincová, E.2    Kozubík, A.3    Jurdic, P.4    Soucek, K.5
  • 53
    • 0037646520 scopus 로고    scopus 로고
    • Growth differentiation factor-15 prevents low potassium-induced cell death of cerebellar granule neurons by differential regulation of Akt and ERK pathways
    • Subramaniam S, Strelau J, Unsicker K, (2003) Growth differentiation factor-15 prevents low potassium-induced cell death of cerebellar granule neurons by differential regulation of Akt and ERK pathways. J Biol Chem 278: 8904-8912.
    • (2003) J Biol Chem , vol.278 , pp. 8904-8912
    • Subramaniam, S.1    Strelau, J.2    Unsicker, K.3


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