Constant and intermittent high glucose enhances endothelial cell apoptosis through mitochondrial superoxide overproduction

Diabetes/Metabolism Research and Reviews

Volumn 22, Issue 3, 2006, Pages 198-203

  Piconi, Ludovica ^a   Quagliaro, Lisa ^a   Assaloni, Roberta ^b   Da Ros, Roberto ^b   Maier, Amabile ^b   Zuodar, Gianni ^b   Ceriello, Antonio ^b  

^a Morpurgo Hofman Research Laboratory on Aging   (Italy)

^b UNIVERSITY OF UDINE   (Italy)

Author keywords

Apoptosis; Endothelium; Intermittent glucose; Mitochondria; Oxidative stress

Indexed keywords

3 NITROTYROSINE; 8 HYDROXYDEOXYGUANOSINE; CASPASE 3; COPPER ZINC SUPEROXIDE DISMUTASE; FREE RADICAL; GLUCOSE; MANGANESE TETRAKIS(4 BENZOIC ACID)PORPHYRIN CHLORIDE; PORPHYRIN DERIVATIVE; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; THENOYLTRIFLUOROACETONE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL DEATH; CONTROLLED STUDY; CULTURE MEDIUM; DIABETES MELLITUS; ENDOTHELIUM CELL; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HYPERGLYCEMIA; MEMBRANE TRANSPORT; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; OSCILLATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

APOPTOSIS; CASPASE 3; CASPASES; CELL CULTURE TECHNIQUES; ENDOTHELIUM, VASCULAR; ENZYME-LINKED IMMUNOSORBENT ASSAY; GLUCOSE; HUMANS; MITOCHONDRIA; PROTO-ONCOGENE PROTEINS C-BCL-2; SUPEROXIDES; UMBILICAL VEINS;

EID: 33744473330     PISSN: 15207552     EISSN: 15207560     Source Type: Journal    
DOI: 10.1002/dmrr.613     Document Type: Article

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