Apoptosis signal-regulating kinase 1 mediates cellular senescence induced by high glucose in endothelial cells

Diabetes

Volumn 55, Issue 6, 2006, Pages 1660-1665

  Yokoi, Toyohiko ^a   Fukuo, Keisuke ^b   Yasuda, Osamu ^a   Hotta, Mizuo ^a   Miyazaki, Junichi ^a   Takemura, Yukihiro ^a   Kawamoto, Hidenobu ^a   Ichijo, Hidenori ^c   Ogihara, Toshio ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b MUKOGAWA WOMEN'S UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

ASK1, apoptosis signal regulating kinase 1; CA ASK1, constitutively active form of ASK1; DN ASK1, dominant negative form of ASK1; HUVEC, human umbilical vein endothelial cell; MAP, mitogen activated protein; PAI 1, plasminogen activator inhibitor 1

Indexed keywords

APOPTOSIS SIGNAL REGULATING KINASE 1; GLUCOSE; PLASMINOGEN ACTIVATOR INHIBITOR 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL AGING; CONTROLLED STUDY; DIABETES MELLITUS; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME MECHANISM; HUMAN; HUMAN CELL; HYPERGLYCEMIA; NONHUMAN; PRIORITY JOURNAL; SENESCENCE; UPREGULATION; WESTERN BLOTTING;

ADENOVIRIDAE; ANALYSIS OF VARIANCE; ANIMALS; BLOTTING, WESTERN; CELL AGING; CELL LINE; DIABETES MELLITUS, EXPERIMENTAL; ENDOTHELIAL CELLS; ENZYME ACTIVATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GLUCOSE; HUMANS; MAP KINASE KINASE KINASE 5; MICE; MICE, KNOCKOUT; PLASMINOGEN ACTIVATOR INHIBITOR 1; SIGNAL TRANSDUCTION; STREPTOZOCIN; TIME FACTORS; TRANSFECTION;

EID: 33748308777     PISSN: 00121797     EISSN: 00121797     Source Type: Journal    
DOI: 10.2337/db05-1607     Document Type: Article

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