메뉴 건너뛰기




Volumn 7, Issue 8, 2012, Pages

Macrophage inhibitory cytokine-1 (MIC-1/GDF15) slows cancer development but increases metastases in TRAMP prostate cancer prone mice

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH DIFFERENTIATION FACTOR 15;

EID: 84865421888     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0043833     Document Type: Article
Times cited : (58)

References (57)
  • 2
    • 12644256640 scopus 로고    scopus 로고
    • MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-beta superfamily
    • Bootcov MR, Bauskin AR, Valenzuela SM, Moore AG, Bansal M, et al. (1997) MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-beta superfamily. Proc Natl Acad Sci U S A 94: 11514-11519.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 11514-11519
    • Bootcov, M.R.1    Bauskin, A.R.2    Valenzuela, S.M.3    Moore, A.G.4    Bansal, M.5
  • 3
    • 33744960940 scopus 로고    scopus 로고
    • Role of macrophage inhibitory cytokine-1 in tumorigenesis and diagnosis of cancer
    • Bauskin AR, Brown DA, Kuffner T, Johnen H, Luo XW, et al. (2006) Role of macrophage inhibitory cytokine-1 in tumorigenesis and diagnosis of cancer. Cancer Res 66: 4983-4986.
    • (2006) Cancer Res , vol.66 , pp. 4983-4986
    • Bauskin, A.R.1    Brown, D.A.2    Kuffner, T.3    Johnen, H.4    Luo, X.W.5
  • 4
    • 80052907593 scopus 로고    scopus 로고
    • The TGF-beta superfamily cytokine, MIC-1/GDF15: a pleotrophic cytokine with roles in inflammation, cancer and metabolism
    • Breit SN, Johnen H, Cook AD, Tsai VW, Mohammad MG, et al. (2011) The TGF-beta superfamily cytokine, MIC-1/GDF15: a pleotrophic cytokine with roles in inflammation, cancer and metabolism. Growth Factors 29: 187-195.
    • (2011) Growth Factors , vol.29 , pp. 187-195
    • Breit, S.N.1    Johnen, H.2    Cook, A.D.3    Tsai, V.W.4    Mohammad, M.G.5
  • 5
    • 0037452997 scopus 로고    scopus 로고
    • Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum
    • Welsh JB, Sapinoso LM, Kern SG, Brown DA, Liu T, et al. (2003) Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum. Proc Natl Acad Sci U S A 100: 3410-3415.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 3410-3415
    • Welsh, J.B.1    Sapinoso, L.M.2    Kern, S.G.3    Brown, D.A.4    Liu, T.5
  • 6
    • 80655149123 scopus 로고    scopus 로고
    • Developing point of care and high-throughput biological assays for determining absorbed radiation dose
    • Joiner MC, Thomas RA, Grever WE, Smolinski JM, Divine GW, et al. (2011) Developing point of care and high-throughput biological assays for determining absorbed radiation dose. Radiother Oncol 101: 233-236.
    • (2011) Radiother Oncol , vol.101 , pp. 233-236
    • Joiner, M.C.1    Thomas, R.A.2    Grever, W.E.3    Smolinski, J.M.4    Divine, G.W.5
  • 7
    • 33645070534 scopus 로고    scopus 로고
    • Pharmacogenomic identification of novel determinants of response to chemotherapy in colon cancer
    • Boyer J, Allen WL, McLean EG, Wilson PM, McCulla A, et al. (2006) Pharmacogenomic identification of novel determinants of response to chemotherapy in colon cancer. Cancer Res 66: 2765-2777.
    • (2006) Cancer Res , vol.66 , pp. 2765-2777
    • Boyer, J.1    Allen, W.L.2    McLean, E.G.3    Wilson, P.M.4    McCulla, A.5
  • 8
    • 5144229762 scopus 로고    scopus 로고
    • Immediate gene expression changes after the first course of neoadjuvant chemotherapy in patients with primary breast cancer disease
    • Modlich O, Prisack HB, Munnes M, Audretsch W, Bojar H, (2004) Immediate gene expression changes after the first course of neoadjuvant chemotherapy in patients with primary breast cancer disease. Clin Cancer Res 10: 6418-6431.
    • (2004) Clin Cancer Res , vol.10 , pp. 6418-6431
    • Modlich, O.1    Prisack, H.B.2    Munnes, M.3    Audretsch, W.4    Bojar, H.5
  • 9
    • 35348827924 scopus 로고    scopus 로고
    • Molecular alterations in prostate carcinomas that associate with in vivo exposure to chemotherapy: identification of a cytoprotective mechanism involving growth differentiation factor 15
    • Huang CY, Beer TM, Higano CS, True LD, Vessella R, et al. (2007) Molecular alterations in prostate carcinomas that associate with in vivo exposure to chemotherapy: identification of a cytoprotective mechanism involving growth differentiation factor 15. Clin Cancer Res 13: 5825-5833.
    • (2007) Clin Cancer Res , vol.13 , pp. 5825-5833
    • Huang, C.Y.1    Beer, T.M.2    Higano, C.S.3    True, L.D.4    Vessella, R.5
  • 10
    • 33646259501 scopus 로고    scopus 로고
    • Aberrant neuropeptide Y and macrophage inhibitory cytokine-1 expression are early events in prostate cancer development and are associated with poor prognosis
    • Rasiah KK, Kench JG, Gardiner-Garden M, Biankin AV, Golovsky D, et al. (2006) Aberrant neuropeptide Y and macrophage inhibitory cytokine-1 expression are early events in prostate cancer development and are associated with poor prognosis. Cancer Epidemiol Biomarkers Prev 15: 711-716.
    • (2006) Cancer Epidemiol Biomarkers Prev , vol.15 , pp. 711-716
    • Rasiah, K.K.1    Kench, J.G.2    Gardiner-Garden, M.3    Biankin, A.V.4    Golovsky, D.5
  • 11
    • 33947229008 scopus 로고    scopus 로고
    • Dynamics of expression of growth differentiation factor 15 in normal and PIN development in the mouse
    • Noorali S, Kurita T, Woolcock B, de Algara TR, Lo M, et al. (2007) Dynamics of expression of growth differentiation factor 15 in normal and PIN development in the mouse. Differentiation 75: 325-336.
    • (2007) Differentiation , vol.75 , pp. 325-336
    • Noorali, S.1    Kurita, T.2    Woolcock, B.3    de Algara, T.R.4    Lo, M.5
  • 12
    • 77953590551 scopus 로고    scopus 로고
    • The TGF-beta superfamily cytokine MIC-1/GDF15: secretory mechanisms facilitate creation of latent stromal stores
    • Bauskin AR, Jiang L, Luo XW, Wu L, Brown DA, et al. (2010) The TGF-beta superfamily cytokine MIC-1/GDF15: secretory mechanisms facilitate creation of latent stromal stores. J Interferon Cytokine Res 30: 389-397.
    • (2010) J Interferon Cytokine Res , vol.30 , pp. 389-397
    • Bauskin, A.R.1    Jiang, L.2    Luo, X.W.3    Wu, L.4    Brown, D.A.5
  • 13
    • 12444303172 scopus 로고    scopus 로고
    • MIC-1 serum level and genotype: associations with progress and prognosis of colorectal carcinoma
    • Brown DA, Ward RL, Buckhaults P, Liu T, Romans KE, et al. (2003) MIC-1 serum level and genotype: associations with progress and prognosis of colorectal carcinoma. Clin Cancer Res 9: 2642-2650.
    • (2003) Clin Cancer Res , vol.9 , pp. 2642-2650
    • Brown, D.A.1    Ward, R.L.2    Buckhaults, P.3    Liu, T.4    Romans, K.E.5
  • 14
    • 70350733627 scopus 로고    scopus 로고
    • Macrophage inhibitory cytokine 1: a new prognostic marker in prostate cancer
    • Brown DA, Lindmark F, Stattin P, Balter K, Adami HO, et al. (2009) Macrophage inhibitory cytokine 1: a new prognostic marker in prostate cancer. Clin Cancer Res 15: 6658-6664.
    • (2009) Clin Cancer Res , vol.15 , pp. 6658-6664
    • Brown, D.A.1    Lindmark, F.2    Stattin, P.3    Balter, K.4    Adami, H.O.5
  • 15
    • 31544440475 scopus 로고    scopus 로고
    • Measurement of serum levels of macrophage inhibitory cytokine 1 combined with prostate-specific antigen improves prostate cancer diagnosis
    • Brown DA, Stephan C, Ward RL, Law M, Hunter M, et al. (2006) Measurement of serum levels of macrophage inhibitory cytokine 1 combined with prostate-specific antigen improves prostate cancer diagnosis. Clin Cancer Res 12: 89-96.
    • (2006) Clin Cancer Res , vol.12 , pp. 89-96
    • Brown, D.A.1    Stephan, C.2    Ward, R.L.3    Law, M.4    Hunter, M.5
  • 16
    • 0042134847 scopus 로고    scopus 로고
    • Macrophage inhibitory cytokine-1 induces the invasiveness of gastric cancer cells by up-regulating the urokinase-type plasminogen activator system
    • Lee DH, Yang Y, Lee SJ, Kim KY, Koo TH, et al. (2003) Macrophage inhibitory cytokine-1 induces the invasiveness of gastric cancer cells by up-regulating the urokinase-type plasminogen activator system. Cancer Res 63: 4648-4655.
    • (2003) Cancer Res , vol.63 , pp. 4648-4655
    • Lee, D.H.1    Yang, Y.2    Lee, S.J.3    Kim, K.Y.4    Koo, T.H.5
  • 17
    • 0038076012 scopus 로고    scopus 로고
    • Quantitative analysis of macrophage inhibitory cytokine-1 (MIC-1) gene expression in human prostatic tissues
    • Nakamura T, Scorilas A, Stephan C, Yousef GM, Kristiansen G, et al. (2003) Quantitative analysis of macrophage inhibitory cytokine-1 (MIC-1) gene expression in human prostatic tissues. Br J Cancer 88: 1101-1104.
    • (2003) Br J Cancer , vol.88 , pp. 1101-1104
    • Nakamura, T.1    Scorilas, A.2    Stephan, C.3    Yousef, G.M.4    Kristiansen, G.5
  • 18
    • 4344567388 scopus 로고    scopus 로고
    • Protein profiling of microdissected prostate tissue links growth differentiation factor 15 to prostate carcinogenesis
    • Cheung PK, Woolcock B, Adomat H, Sutcliffe M, Bainbridge TC, et al. (2004) Protein profiling of microdissected prostate tissue links growth differentiation factor 15 to prostate carcinogenesis. Cancer Res 64: 5929-5933.
    • (2004) Cancer Res , vol.64 , pp. 5929-5933
    • Cheung, P.K.1    Woolcock, B.2    Adomat, H.3    Sutcliffe, M.4    Bainbridge, T.C.5
  • 19
    • 11144353917 scopus 로고    scopus 로고
    • Serum macrophage inhibitory cytokine 1 as a marker of pancreatic and other periampullary cancers
    • Koopmann J, Buckhaults P, Brown DA, Zahurak ML, Sato N, et al. (2004) Serum macrophage inhibitory cytokine 1 as a marker of pancreatic and other periampullary cancers. Clin Cancer Res 10: 2386-2392.
    • (2004) Clin Cancer Res , vol.10 , pp. 2386-2392
    • Koopmann, J.1    Buckhaults, P.2    Brown, D.A.3    Zahurak, M.L.4    Sato, N.5
  • 20
    • 34047209514 scopus 로고    scopus 로고
    • Prostate-derived factor as a paracrine and autocrine factor for the proliferation of androgen receptor-positive human prostate cancer cells
    • Chen SJ, Karan D, Johansson SL, Lin FF, Zeckser J, et al. (2007) Prostate-derived factor as a paracrine and autocrine factor for the proliferation of androgen receptor-positive human prostate cancer cells. Prostate 67: 557-571.
    • (2007) Prostate , vol.67 , pp. 557-571
    • Chen, S.J.1    Karan, D.2    Johansson, S.L.3    Lin, F.F.4    Zeckser, J.5
  • 21
    • 34047253916 scopus 로고    scopus 로고
    • Serum macrophage inhibitory cytokine-1 concentrations correlate with the presence of prostate cancer bone metastases
    • Selander KS, Brown DA, Sequeiros GB, Hunter M, Desmond R, et al. (2007) Serum macrophage inhibitory cytokine-1 concentrations correlate with the presence of prostate cancer bone metastases. Cancer Epidemiol Biomarkers Prev 16: 532-537.
    • (2007) Cancer Epidemiol Biomarkers Prev , vol.16 , pp. 532-537
    • Selander, K.S.1    Brown, D.A.2    Sequeiros, G.B.3    Hunter, M.4    Desmond, R.5
  • 22
    • 58549108814 scopus 로고    scopus 로고
    • Upregulation and secretion of macrophage inhibitory cytokine-1 (MIC-1) in gastric cancers
    • Baek KE, Yoon SR, Kim JT, Kim KS, Kang SH, et al. (2009) Upregulation and secretion of macrophage inhibitory cytokine-1 (MIC-1) in gastric cancers. Clin Chim Acta 401: 128-133.
    • (2009) Clin Chim Acta , vol.401 , pp. 128-133
    • Baek, K.E.1    Yoon, S.R.2    Kim, J.T.3    Kim, K.S.4    Kang, S.H.5
  • 23
    • 70350712285 scopus 로고    scopus 로고
    • Elevated levels of MIC-1/GDF15 in the cerebrospinal fluid of patients are associated with glioblastoma and worse outcome
    • Shnaper S, Desbaillets I, Brown DA, Murat A, Migliavacca E, et al. (2009) Elevated levels of MIC-1/GDF15 in the cerebrospinal fluid of patients are associated with glioblastoma and worse outcome. Int J Cancer 125: 2624-2630.
    • (2009) Int J Cancer , vol.125 , pp. 2624-2630
    • Shnaper, S.1    Desbaillets, I.2    Brown, D.A.3    Murat, A.4    Migliavacca, E.5
  • 24
    • 70350225568 scopus 로고    scopus 로고
    • Identification of candidate biomarkers of therapeutic response to docetaxel by proteomic profiling
    • Zhao L, Lee BY, Brown DA, Molloy MP, Marx GM, et al. (2009) Identification of candidate biomarkers of therapeutic response to docetaxel by proteomic profiling. Cancer Res 69: 7696-7703.
    • (2009) Cancer Res , vol.69 , pp. 7696-7703
    • Zhao, L.1    Lee, B.Y.2    Brown, D.A.3    Molloy, M.P.4    Marx, G.M.5
  • 25
    • 79955810854 scopus 로고    scopus 로고
    • Growth differentiation factor 15: a prognostic marker for recurrence in colorectal cancer
    • Wallin U, Glimelius B, Jirstrom K, Darmanis S, Nong RY, et al. (2011) Growth differentiation factor 15: a prognostic marker for recurrence in colorectal cancer. Br J Cancer 104: 1619-1627.
    • (2011) Br J Cancer , vol.104 , pp. 1619-1627
    • Wallin, U.1    Glimelius, B.2    Jirstrom, K.3    Darmanis, S.4    Nong, R.Y.5
  • 26
    • 77955555369 scopus 로고    scopus 로고
    • Growth differentiation factor-15 as a prognostic biomarker in ovarian cancer
    • Staff AC, Bock AJ, Becker C, Kempf T, Wollert KC, et al. (2010) Growth differentiation factor-15 as a prognostic biomarker in ovarian cancer. Gynecol Oncol 118: 237-243.
    • (2010) Gynecol Oncol , vol.118 , pp. 237-243
    • Staff, A.C.1    Bock, A.J.2    Becker, C.3    Kempf, T.4    Wollert, K.C.5
  • 27
    • 79960390271 scopus 로고    scopus 로고
    • Elevated plasma growth differentiation factor-15 correlates with lymph node metastases and poor survival in endometrial cancer
    • Staff AC, Trovik J, Eriksson AG, Wik E, Wollert KC, et al. (2011) Elevated plasma growth differentiation factor-15 correlates with lymph node metastases and poor survival in endometrial cancer. Clin Cancer Res 17: 4825-4833.
    • (2011) Clin Cancer Res , vol.17 , pp. 4825-4833
    • Staff, A.C.1    Trovik, J.2    Eriksson, A.G.3    Wik, E.4    Wollert, K.C.5
  • 28
    • 58449129853 scopus 로고    scopus 로고
    • Macrophage inhibitory cytokine-1 is overexpressed in malignant melanoma and is associated with tumorigenicity
    • Boyle GM, Pedley J, Martyn AC, Banducci KJ, Strutton GM, et al. (2009) Macrophage inhibitory cytokine-1 is overexpressed in malignant melanoma and is associated with tumorigenicity. J Invest Dermatol 129: 383-391.
    • (2009) J Invest Dermatol , vol.129 , pp. 383-391
    • Boyle, G.M.1    Pedley, J.2    Martyn, A.C.3    Banducci, K.J.4    Strutton, G.M.5
  • 30
    • 31544450588 scopus 로고    scopus 로고
    • Serum markers in patients with resectable pancreatic adenocarcinoma: macrophage inhibitory cytokine 1 versus CA19-9
    • Koopmann J, Rosenzweig CN, Zhang Z, Canto MI, Brown DA, et al. (2006) Serum markers in patients with resectable pancreatic adenocarcinoma: macrophage inhibitory cytokine 1 versus CA19-9. Clin Cancer Res 12: 442-446.
    • (2006) Clin Cancer Res , vol.12 , pp. 442-446
    • Koopmann, J.1    Rosenzweig, C.N.2    Zhang, Z.3    Canto, M.I.4    Brown, D.A.5
  • 31
    • 21044448035 scopus 로고    scopus 로고
    • Genetic classification of benign and malignant thyroid follicular neoplasia based on a three-gene combination
    • Weber F, Shen L, Aldred MA, Morrison CD, Frilling A, et al. (2005) Genetic classification of benign and malignant thyroid follicular neoplasia based on a three-gene combination. J Clin Endocrinol Metab 90: 2512-2521.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 2512-2521
    • Weber, F.1    Shen, L.2    Aldred, M.A.3    Morrison, C.D.4    Frilling, A.5
  • 32
    • 33645474441 scopus 로고    scopus 로고
    • Gene expression in poorly differentiated papillary thyroid carcinomas
    • Fluge O, Bruland O, Akslen LA, Lillehaug JR, Varhaug JE, (2006) Gene expression in poorly differentiated papillary thyroid carcinomas. Thyroid 16: 161-175.
    • (2006) Thyroid , vol.16 , pp. 161-175
    • Fluge, O.1    Bruland, O.2    Akslen, L.A.3    Lillehaug, J.R.4    Varhaug, J.E.5
  • 33
    • 35948981520 scopus 로고    scopus 로고
    • Tumor-induced anorexia and weight loss are mediated by the TGF-beta superfamily cytokine MIC-1
    • Johnen H, Lin S, Kuffner T, Brown DA, Tsai VW, et al. (2007) Tumor-induced anorexia and weight loss are mediated by the TGF-beta superfamily cytokine MIC-1. Nat Med 13: 1333-1340.
    • (2007) Nat Med , vol.13 , pp. 1333-1340
    • Johnen, H.1    Lin, S.2    Kuffner, T.3    Brown, D.A.4    Tsai, V.W.5
  • 34
    • 20144389237 scopus 로고    scopus 로고
    • The propeptide mediates formation of stromal stores of PROMIC-1: role in determining prostate cancer outcome
    • Bauskin AR, Brown DA, Junankar S, Rasiah KK, Eggleton S, et al. (2005) The propeptide mediates formation of stromal stores of PROMIC-1: role in determining prostate cancer outcome. Cancer Res 65: 2330-2336.
    • (2005) Cancer Res , vol.65 , pp. 2330-2336
    • Bauskin, A.R.1    Brown, D.A.2    Junankar, S.3    Rasiah, K.K.4    Eggleton, S.5
  • 35
    • 0035060429 scopus 로고    scopus 로고
    • Cyclooxygenase inhibitors regulate the expression of a TGF-beta superfamily member that has proapoptotic and antitumorigenic activities
    • Baek SJ, Kim KS, Nixon JB, Wilson LC, Eling TE, (2001) Cyclooxygenase inhibitors regulate the expression of a TGF-beta superfamily member that has proapoptotic and antitumorigenic activities. Mol Pharmacol 59: 901-908.
    • (2001) Mol Pharmacol , vol.59 , pp. 901-908
    • Baek, S.J.1    Kim, K.S.2    Nixon, J.B.3    Wilson, L.C.4    Eling, T.E.5
  • 36
    • 0043016358 scopus 로고    scopus 로고
    • Macrophage inhibitory cytokine 1 reduces cell adhesion and induces apoptosis in prostate cancer cells
    • Liu T, Bauskin AR, Zaunders J, Brown DA, Pankhurst S, et al. (2003) Macrophage inhibitory cytokine 1 reduces cell adhesion and induces apoptosis in prostate cancer cells. Cancer Res 63: 5034-5040.
    • (2003) Cancer Res , vol.63 , pp. 5034-5040
    • Liu, T.1    Bauskin, A.R.2    Zaunders, J.3    Brown, D.A.4    Pankhurst, S.5
  • 37
    • 15944422900 scopus 로고    scopus 로고
    • The conventional nonsteroidal anti-inflammatory drug sulindac sulfide arrests ovarian cancer cell growth via the expression of NAG-1/MIC-1/GDF-15
    • Kim JS, Baek SJ, Sali T, Eling TE, (2005) The conventional nonsteroidal anti-inflammatory drug sulindac sulfide arrests ovarian cancer cell growth via the expression of NAG-1/MIC-1/GDF-15. Mol Cancer Ther 4: 487-493.
    • (2005) Mol Cancer Ther , vol.4 , pp. 487-493
    • Kim, J.S.1    Baek, S.J.2    Sali, T.3    Eling, T.E.4
  • 38
    • 34247623111 scopus 로고    scopus 로고
    • Celecoxib induces apoptosis in COX-2 deficient human gastric cancer cells through Akt/GSK3beta/NAG-1 pathway
    • Pang RP, Zhou JG, Zeng ZR, Li XY, Chen W, et al. (2007) Celecoxib induces apoptosis in COX-2 deficient human gastric cancer cells through Akt/GSK3beta/NAG-1 pathway. Cancer Lett 251: 268-277.
    • (2007) Cancer Lett , vol.251 , pp. 268-277
    • Pang, R.P.1    Zhou, J.G.2    Zeng, Z.R.3    Li, X.Y.4    Chen, W.5
  • 39
    • 12844260806 scopus 로고    scopus 로고
    • Indole-3-carbinol and 3,3'-diindolylmethane induce expression of NAG-1 in a p53-independent manner
    • Lee SH, Kim JS, Yamaguchi K, Eling TE, Baek SJ, (2005) Indole-3-carbinol and 3,3'-diindolylmethane induce expression of NAG-1 in a p53-independent manner. Biochem Biophys Res Commun 328: 63-69.
    • (2005) Biochem Biophys Res Commun , vol.328 , pp. 63-69
    • Lee, S.H.1    Kim, J.S.2    Yamaguchi, K.3    Eling, T.E.4    Baek, S.J.5
  • 40
    • 41849104687 scopus 로고    scopus 로고
    • Macrophage inhibitory cytokine-1 activates AKT and ERK-1/2 via the transactivation of ErbB2 in human breast and gastric cancer cells
    • Kim KK, Lee JJ, Yang Y, You KH, Lee JH, (2008) Macrophage inhibitory cytokine-1 activates AKT and ERK-1/2 via the transactivation of ErbB2 in human breast and gastric cancer cells. Carcinogenesis 29: 704-712.
    • (2008) Carcinogenesis , vol.29 , pp. 704-712
    • Kim, K.K.1    Lee, J.J.2    Yang, Y.3    You, K.H.4    Lee, J.H.5
  • 41
    • 67549138951 scopus 로고    scopus 로고
    • Expression of growth differentiation factor 15 is positively correlated with histopathological malignant grade and in vitro cell proliferation in oral squamous cell carcinoma
    • Zhang L, Yang X, Pan HY, Zhou XJ, Li J, et al. (2009) Expression of growth differentiation factor 15 is positively correlated with histopathological malignant grade and in vitro cell proliferation in oral squamous cell carcinoma. Oral Oncol 45: 627-632.
    • (2009) Oral Oncol , vol.45 , pp. 627-632
    • Zhang, L.1    Yang, X.2    Pan, H.Y.3    Zhou, X.J.4    Li, J.5
  • 42
    • 77949267633 scopus 로고    scopus 로고
    • Overexpression of macrophage inhibitory cytokine-1 induces metastasis of human prostate cancer cells through the FAK-RhoA signaling pathway
    • Senapati S, Rachagani S, Chaudhary K, Johansson SL, Singh RK, et al. (2010) Overexpression of macrophage inhibitory cytokine-1 induces metastasis of human prostate cancer cells through the FAK-RhoA signaling pathway. Oncogene 29: 1293-1302.
    • (2010) Oncogene , vol.29 , pp. 1293-1302
    • Senapati, S.1    Rachagani, S.2    Chaudhary, K.3    Johansson, S.L.4    Singh, R.K.5
  • 43
    • 0037142612 scopus 로고    scopus 로고
    • Anoxia induces macrophage inhibitory cytokine-1 (MIC-1) in glioblastoma cells independently of p53 and HIF-1
    • Albertoni M, Shaw PH, Nozaki M, Godard S, Tenan M, et al. (2002) Anoxia induces macrophage inhibitory cytokine-1 (MIC-1) in glioblastoma cells independently of p53 and HIF-1. Oncogene 21: 4212-4219.
    • (2002) Oncogene , vol.21 , pp. 4212-4219
    • Albertoni, M.1    Shaw, P.H.2    Nozaki, M.3    Godard, S.4    Tenan, M.5
  • 48
    • 0030860498 scopus 로고    scopus 로고
    • Characterization of prostatic epithelial cell lines derived from transgenic adenocarcinoma of the mouse prostate (TRAMP) model
    • Foster BA, Gingrich JR, Kwon ED, Madias C, Greenberg NM, (1997) Characterization of prostatic epithelial cell lines derived from transgenic adenocarcinoma of the mouse prostate (TRAMP) model. Cancer Res 57: 3325-3330.
    • (1997) Cancer Res , vol.57 , pp. 3325-3330
    • Foster, B.A.1    Gingrich, J.R.2    Kwon, E.D.3    Madias, C.4    Greenberg, N.M.5
  • 49
    • 41849149009 scopus 로고    scopus 로고
    • Broadening of transgenic adenocarcinoma of the mouse prostate (TRAMP) model to represent late stage androgen depletion independent cancer
    • Jeet V, Ow K, Doherty E, Curley B, Russell PJ, et al. (2008) Broadening of transgenic adenocarcinoma of the mouse prostate (TRAMP) model to represent late stage androgen depletion independent cancer. Prostate 68: 548-562.
    • (2008) Prostate , vol.68 , pp. 548-562
    • Jeet, V.1    Ow, K.2    Doherty, E.3    Curley, B.4    Russell, P.J.5
  • 50
    • 2442701601 scopus 로고    scopus 로고
    • Macrophage inhibitory cytokine-1: a novel biomarker for p53 pathway activation
    • Yang H, Filipovic Z, Brown D, Breit SN, Vassilev LT, (2003) Macrophage inhibitory cytokine-1: a novel biomarker for p53 pathway activation. Mol Cancer Ther 2: 1023-1029.
    • (2003) Mol Cancer Ther , vol.2 , pp. 1023-1029
    • Yang, H.1    Filipovic, Z.2    Brown, D.3    Breit, S.N.4    Vassilev, L.T.5
  • 51
    • 29744437499 scopus 로고    scopus 로고
    • Growth differentiation factor-15: induction in liver injury through p53 and tumor necrosis factor-independent mechanisms
    • Zimmers TA, Jin X, Hsiao EC, Perez EA, Pierce RH, et al. (2006) Growth differentiation factor-15: induction in liver injury through p53 and tumor necrosis factor-independent mechanisms. J Surg Res 130: 45-51.
    • (2006) J Surg Res , vol.130 , pp. 45-51
    • Zimmers, T.A.1    Jin, X.2    Hsiao, E.C.3    Perez, E.A.4    Pierce, R.H.5
  • 52
    • 61849084730 scopus 로고    scopus 로고
    • p53 controls prostate-derived factor/macrophage inhibitory cytokine/NSAID-activated gene expression in response to cell density, DNA damage and hypoxia through diverse mechanisms
    • Kelly JA, Lucia MS, Lambert JR, (2009) p53 controls prostate-derived factor/macrophage inhibitory cytokine/NSAID-activated gene expression in response to cell density, DNA damage and hypoxia through diverse mechanisms. Cancer Lett 277: 38-47.
    • (2009) Cancer Lett , vol.277 , pp. 38-47
    • Kelly, J.A.1    Lucia, M.S.2    Lambert, J.R.3
  • 53
    • 33947153891 scopus 로고    scopus 로고
    • Serum macrophage inhibitory cytokine 1 in rheumatoid arthritis: a potential marker of erosive joint destruction
    • Brown DA, Moore J, Johnen H, Smeets TJ, Bauskin AR, et al. (2007) Serum macrophage inhibitory cytokine 1 in rheumatoid arthritis: a potential marker of erosive joint destruction. Arthritis Rheum 56: 753-764.
    • (2007) Arthritis Rheum , vol.56 , pp. 753-764
    • Brown, D.A.1    Moore, J.2    Johnen, H.3    Smeets, T.J.4    Bauskin, A.R.5
  • 54
    • 33750736082 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drug-activated gene-1 over expression in transgenic mice suppresses intestinal neoplasia
    • Baek SJ, Okazaki R, Lee SH, Martinez J, Kim JS, et al. (2006) Nonsteroidal anti-inflammatory drug-activated gene-1 over expression in transgenic mice suppresses intestinal neoplasia. Gastroenterology 131: 1553-1560.
    • (2006) Gastroenterology , vol.131 , pp. 1553-1560
    • Baek, S.J.1    Okazaki, R.2    Lee, S.H.3    Martinez, J.4    Kim, J.S.5
  • 55
    • 77949264215 scopus 로고    scopus 로고
    • Loss of GDF-15 abolishes sulindac chemoprevention in the ApcMin/+ mouse model of intestinal cancer
    • Zimmers TA, Gutierrez JC, Koniaris LG, (2010) Loss of GDF-15 abolishes sulindac chemoprevention in the ApcMin/+ mouse model of intestinal cancer. J Cancer Res Clin Oncol 136: 571-576.
    • (2010) J Cancer Res Clin Oncol , vol.136 , pp. 571-576
    • Zimmers, T.A.1    Gutierrez, J.C.2    Koniaris, L.G.3
  • 56
    • 84863140892 scopus 로고    scopus 로고
    • Serum Macrophage Inhibitory Cytokine-1 (MIC-1/GDF15): A Potential Screening Tool for the Prevention of Colon Cancer?
    • Brown DA, Hance KW, Rogers CJ, Sansbury LB, Albert PS, et al. (2012) Serum Macrophage Inhibitory Cytokine-1 (MIC-1/GDF15): A Potential Screening Tool for the Prevention of Colon Cancer? Cancer Epidemiol Biomarkers Prev 21: 337-346.
    • (2012) Cancer Epidemiol Biomarkers Prev , vol.21 , pp. 337-346
    • Brown, D.A.1    Hance, K.W.2    Rogers, C.J.3    Sansbury, L.B.4    Albert, P.S.5
  • 57
    • 47549090432 scopus 로고    scopus 로고
    • TGFbeta in Cancer
    • Massague J, (2008) TGFbeta in Cancer. Cell 134: 215-230.
    • (2008) Cell , vol.134 , pp. 215-230
    • Massague, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.