Targeting testis-specific proteins to inhibit spermatogenesis: Lesson from endocrine disrupting chemicals

Expert Opinion on Therapeutic Targets

Volumn 17, Issue 7, 2013, Pages 839-855

  Wan, H T ^a   Mruk, Dolores D ^a   Wong, Chris Kc ^b   Cheng, C Yan ^a  

^a POPULATION COUNCIL   (United States)

^b HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

Author keywords

Blood testis barrier; Endocrine disrupting chemicals; Spermatogenesis; Steroidogenesis; Testis; Testis specific proteins

Indexed keywords

ANDROGEN BINDING PROTEIN; AROMATASE; CADMIUM; DESMOGLEIN 2; ENDOCRINE DISRUPTOR; GONADOTROPIN; HEAVY METAL; INHIBIN B; LIOTHYRONINE; METHYLMERCURY; MUELLERIAN INHIBITING FACTOR; MULTIDRUG RESISTANCE PROTEIN; OXYGEN DERIVATIVE; PEPTIDE HORMONE; PLASTICIZER; RETINOID X RECEPTOR; SURFACTANT; TESTOSTERONE;

ANDROGEN SYNTHESIS; APOPTOSIS; AROMATIZATION; BLOOD; DOWN REGULATION; ENDOPLASMIC RETICULUM; ESTROGEN RESPONSIVE ELEMENT; FEEDBACK SYSTEM; GENE EXPRESSION; GENETIC TRANSCRIPTION; GERM CELL; HALF LIFE TIME; HORMONAL REGULATION; HUMAN; LEYDIG CELL; MALE GENITAL SYSTEM; MALE INFERTILITY; MICROENVIRONMENT; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN TARGETING; REPRODUCTION; REPRODUCTIVE TOXICITY; REVIEW; SEMINIFEROUS TUBULE; SEMINIFEROUS TUBULE EPITHELIUM; SERTOLI CELL; SPERMATOGENESIS; SPERMATOZOON COUNT; STEROIDOGENESIS; TESTIS; TESTIS DEVELOPMENT; TESTIS FUNCTION; TESTOSTERONE BLOOD LEVEL; TESTOSTERONE SYNTHESIS; TIGHT JUNCTION;

ANIMALS; BLOOD-TESTIS BARRIER; ENDOCRINE DISRUPTORS; HUMANS; MALE; PROTEINS; REACTIVE OXYGEN SPECIES; SPERMATOGENESIS; TESTIS;

EID: 84879054260     PISSN: 14728222     EISSN: 17447631     Source Type: Journal    
DOI: 10.1517/14728222.2013.791679     Document Type: Review

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