Serum inhibin-b in fertile men is strongly correlated with low but not high sperm counts: A coordinated study of 1,797 European and US men

Fertility and Sterility

Volumn 94, Issue 6, 2010, Pages 2128-2134

  Jørgensen, Niels ^a   Liu, Fan ^b   Andersson, Anna Maria ^a   Vierula, Matti ^c   Irvine, D Stewart ^d   Auger, Jacques ^e   Brazil, Charlene K ^f   Drobnis, Erma Z ^g   Jensen, Tina K ^a   Jouannet, Pierre ^e   Overstreet, James W ^f   Redmon, J Bruce ^h   Sparks, Amy ⁱ   Toppari, Jorma ^c   Wang, Christina ^j   Skakkebæk, Niels E ^a   Swan, Shanna H ^b  

^a Rigshospitalet   (Denmark)

^b UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^c TURKU UNIVERSITY HOSPITAL   (Finland)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

^e UNIVERSITÉ PARIS DESCARTES   (France)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g University of Missouri   (United States)

^h UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

ⁱ UNIVERSITY OF IOWA   (United States)

^j HARBOR UCLA MEDICAL CENTER   (United States)

more..

Author keywords

fertile men; follicle stimulating hormone; Inhibin b; sperm concentration; total sperm count

Indexed keywords

BIOLOGICAL MARKER; FOLLITROPIN; INHIBIN B;

ARTICLE; BLOOD SAMPLING; HUMAN; HUMAN CELL; MALE; MALE FERTILITY; MORPHOLOGY; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SPERMATOGENESIS; SPERMATOZOON COUNT;

ADULT; BIOLOGICAL MARKERS; BLOOD SPECIMEN COLLECTION; CIRCADIAN RHYTHM; CROSS-SECTIONAL STUDIES; EUROPE; FERTILITY; HUMANS; INHIBINS; MALE; MIDDLE AGED; OLIGOSPERMIA; PREDICTIVE VALUE OF TESTS; SPERM COUNT; TIME FACTORS; UNITED STATES; YOUNG ADULT;

EID: 78049281395     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2009.12.051     Document Type: Article

References (17)

1. N. Groome, and M. O'Brien Immunoassays for inhibin and its subunits. Further applications of the synthetic peptide approach J Immunol Methods 165 1993 167 176
2. T.K. Jensen, A.M. Andersson, N.H. Hjollund, T. Scheike, H. Kolstad, and A. Giwercman Inhibin B as a serum marker of spermatogenesis: correlation to differences in sperm concentration and follicle-stimulating hormone levels. A study of 349 Danish men J Clin Endocrinol Metab 82 1997 4059 4063
3. A.M. Andersson, J.H. Petersen, N. Jorgensen, T.K. Jensen, and N.E. Skakkebaek Serum inhibin B and follicle-stimulating hormone levels as tools in the evaluation of infertile men: significance of adequate reference values from proven fertile men J Clin Endocrinol Metab 89 2004 2873 2879
4. F.H. Pierik, J.T. Vreeburg, T. Stijnen, F.H. De Jong, and R.F. Weber Serum inhibin B as a marker of spermatogenesis J Clin Endocrinol Metab 83 1998 3110 3114
5. J.D. Meeker, L. Godfrey-Bailey, and R. Hauser Relationships between serum hormone levels and semen quality among men from an infertility clinic J Androl 28 2007 397 406
6. E. Carlsen, C. Olsson, J.H. Petersen, A.M. Andersson, and N.E. Skakkebaek Diurnal rhythm in serum levels of inhibin B in normal men: relation to testicular steroids and gonadotropins J Clin Endocrinol Metab 84 1999 1664 1669
7. N. Jørgensen, A.G. Andersen, F. Eustache, D.S. Irvine, J. Suominen, and J.H. Petersen Regional differences in semen quality in Europe Hum Reprod 16 2001 1012 1019 (Pubitemid 32451842)
8. S.H. Swan, C. Brazil, E.Z. Drobnis, F. Liu, R.L. Kruse, and M. Hatch Geographic differences in semen quality of fertile U.S. males Environ Health Perspect 111 2003 414 420
9. World Health Organization WHO laboratory manual for the examination of human semen and sperm-cervical mucus interaction 1992 Cambridge University Press Cambridge
10. N. Jørgensen, J. Auger, A. Giwercman, D.S. Irvine, T.K. Jensen, and P. Jouannet Semen analysis performed by different laboratory teams: an intervariation study Int J Androl 20 1997 201 208
11. R. Menkveld, F.S. Stander, T.J. Kotze, T.F. Kruger, and J.A. van Zyl The evaluation of morphological characteristics of human spermatozoa according to stricter criteria Hum Reprod 5 1990 586 592
12. J.P. Bonde, E. Ernst, T.K. Jensen, N.H. Hjollund, H. Kolstad, and T.B. Henriksen Relation between semen quality and fertility: a population-based study of 430 first-pregnancy planners Lancet 352 1998 1172 1177
13. D.S. Guzick, J.W. Overstreet, P. Factor-Litvak, C.K. Brazil, S.T. Nakajima, and C. Coutifaris Sperm morphology, motility, and concentration in fertile and infertile men N Engl J Med 345 2001 1388 1393
14. R. Slama, F. Eustache, B. Ducot, T.K. Jensen, N. Jørgensen, and A. Horte Time to pregnancy and semen parameters: a cross-sectional study among fertile couples from four European cities Hum Reprod 17 2002 503 515
15. M.L. Uhler, M.J. Zinaman, C.C. Brown, and E.D. Clegg Relationship between sperm characteristics and hormonal parameters in normal couples Fertil Steril 79 Suppl 3 2003 1535 1542
16. A.M. Andersson, J. Müller, and N.E. Skakkebæk Different roles of prepubertal and postpubertal germ cells and Sertoli cells in the regulation of serum inhibin b levels J Clin Endocrinol Metab 83 1998 4451 4458
17. D.A. Adamopoulos, A. Pappa, E. Billa, S.C. Nicopoulou, E. Koukkou, and E. Venekai Seasonality in sperm parameters in normal men and dyspermic patients on medical entervention Andrologia 41 2009 118 124