Bisphenol A impairs insulin signaling and glucose homeostasis and decreases steroidogenesis in rat testis: An in vivo and in silico study

Food and Chemical Toxicology

Volumn 50, Issue 3-4, 2012, Pages 1124-1133

  D'Cruz, Shereen Cynthia ^a   Jubendradass, Rajamanickam ^a   Jayakanthan, Mannu ^a   Rani, Sivaraj Judith Amala ^a   Mathur, Premendu Prakash ^a  

^a PONDICHERRY UNIVERSITY   (India)

Author keywords

Bisphenol A; Glucose transporter 2; Insulin signaling; Steroidogenesis; Testis

Indexed keywords

3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; 4,4' ISOPROPYLIDENEDIPHENOL; CYTOCHALASIN B; ESTRADIOL; GLUCOSE; GLUCOSE TRANSPORTER; GLUCOSE TRANSPORTER 2; GLUCOSE TRANSPORTER 8; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; PHOSPHATIDYLINOSITOL 3 KINASE; STEROIDOGENIC ACUTE REGULATORY PROTEIN; TESTOSTERONE; TESTOSTERONE 17BETA DEHYDROGENASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; COMPUTER MODEL; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOWN REGULATION; GLUCOSE HOMEOSTASIS; GLUCOSE TRANSPORT; IN VIVO STUDY; MALE; MOLECULAR DOCKING; MOLECULAR MODEL; NONHUMAN; RAT; REPRODUCTIVE TOXICITY; SIGNAL TRANSDUCTION; STEROIDOGENESIS; TESTIS DISEASE; TESTIS FUNCTION;

ANIMALS; CATALASE; GLUCOSE; GLUCOSE TRANSPORT PROTEINS, FACILITATIVE; GLUCOSE TRANSPORTER TYPE 2; HOMEOSTASIS; INSULIN; LIPID PEROXIDATION; MALE; PHENOLS; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; STEROIDS; SUPEROXIDE DISMUTASE; TESTIS;

RATTUS;

EID: 84856473551     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2011.11.041     Document Type: Article

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