Impairment of spermatogenesis in rats by mercuric chloride: Involvement of low 17β-estradiol level in induction of acute oxidative stress

Biological Trace Element Research

Volumn 142, Issue 3, 2011, Pages 598-610

  Boujbiha, Mohamed Ali Medali ^a   Hamden, Khaled ^a   Guermazi, Fadhel ^b   Bouslama, Ali ^c   Omezzine, Asma ^c   El Feki, Abdelfattah ^a  

^a Faculté des Sciences de Sfax   (Tunisia)

^b HABIB BOURGUIBA HOSPITAL   (Tunisia)

^c SAHLOUL UNIVERSITY HOSPITAL   (Tunisia)

Author keywords

17 estradiol; Catalase; Glutathione peroxidase; Hypospermatogenesis; Mercuric chloride; Oxidative stress; Reactive oxygen species; Superoxide dismutase

Indexed keywords

ALPHA FETOPROTEIN; CATALASE; CHORIONIC GONADOTROPIN; ESTRADIOL; GLUTATHIONE PEROXIDASE; LACTATE DEHYDROGENASE; MERCURIC CHLORIDE; SUPEROXIDE DISMUTASE; TESTOSTERONE;

ACUTE STRESS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; EPIDIDYMIS; ESTRADIOL BLOOD LEVEL; HISTOPATHOLOGY; HYPOSPERMATOGENESIS; LIPID PEROXIDATION; MALE; MALE INFERTILITY; NONHUMAN; OXIDATIVE STRESS; RAT; SEMINIFEROUS TUBULE; SPERMATID; SPERMATOGENESIS; SPERMATOZOON COUNT; SPERMATOZOON MATURATION; SPERMATOZOON MOTILITY; TESTOSTERONE BLOOD LEVEL;

ANIMALS; CATALASE; ESTRADIOL; GLUTATHIONE PEROXIDASE; LIPID PEROXIDATION; MALE; MERCURIC CHLORIDE; OXIDATIVE STRESS; RADIOIMMUNOASSAY; RATS; RATS, WISTAR; SPERM COUNT; SPERM MOTILITY; SPERMATOGENESIS; SUPEROXIDE DISMUTASE; TESTIS;

ANIMALIA; RATTUS;

EID: 80051793912     PISSN: 01634984     EISSN: 15590720     Source Type: Journal    
DOI: 10.1007/s12011-010-8774-2     Document Type: Article

References (49)

1. Weinbauer GF, Wessels J (1999) Pararcrine control of spermatogenesis. Androlo 31:294-262
2. Carreau S, Delalande C, Silandre D, Bourguiba S, Lambard S (2006) Aromatase and estrogen receptor in male reproduction. Mol Cell Endocrinol 246:65-68 (Pubitemid 43238398)
3. Vételé F, Carreau S, Bourguiba S, Selva J, Benhamed M (2003) Récepteurs aux oestrogènes et spermatogenèse. Reprod Hum Horm 16:407-420
4. Rao MV (1997) Mercury and its effects on mammalian systems-a critical review. Indian J Environ Toxicol 7:3-11
5. Keck C, Bergman M, Ernst E, Mooler C, Klinsch S, Nieschlag E (1993) Autometallographic detection of mercury in testicular tissue of an infertile men exposed to mercury vapour. Reprod Toxicol 7:469-475
6. Mandava VR, Sharma PSN (2001) Protective effect of vitamin E against mercuric chloride reproductive toxicity in male mice. Reprod Toxicol 15:705-712
7. BoujbihaMA, Hamden K, Guermazi F, Bousslama A, Omezine A, Kammoun A, El Feki A (2009) Testicular toxicity in mercuric chloride treated rats: association with oxidative stress. Reprod Toxicol 28:81-89
8. Khan AT, Atkinson A, Graham TC, Thompson SJ, Ali S, Shireen KF (2004) Effects of inorganic mercury on reproductive performance of mice. Food Chem Toxicol 42:571-577 (Pubitemid 38314827)
9. Agarwal A, Said TM (2006) Role of sperm chromatin abnormalities and DNA damage in male infertility. Hum Reprod Update 9:331-345
10. Aitken RJ, Baker MA, Sawyer D (2003) Oxidative stress in the male germ line and its role in the aetiologie of male infertility and genetic disease. Reprod Biomed Online 7:65-70 (Pubitemid 36874408)
11. Sener G, Sehirli O, Tozan A, Velioglu-Ovunc A, Gedik N, Omurtag GZ (2007) Ginkgo biloba extract protects against mercury(II)-induced oxidative tissue damage in rats. Food Chem Toxicol 45:543-550 (Pubitemid 46209456)
12. Sharma AK, Kapadia AG, Fransis P, Rao MV (1996) Reversible effects of mercuric chloride on reproductive organs of the male mouse. Reprod Toxicol 10:153-159
13. Valko M, Rhodes CJ, Moncol J, Izakovic M, Mazur M (2006) Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chem Biol Interac 160:1-40 (Pubitemid 43227479)
14. Su L, Wang M, Yin ST, Wang HL, Chen L, Sun LG, Ruan DY (2008) The interaction of selenium and mercury in the accumulations and oxidative stress of rat tissues. Ecotoxicol Environ Saf 70:438-489
15. Tatjana SK, Silvana AA, Desanka M, Radmila ZK (2000) Inhibitory effects of stress-activated nitric oxide on antioxidant enzymes and testicular steroidogenesis. J Steroid Biochem Mol Biol 75:299-306
16. Debnath D, Mandal TK (2000) Study of quinalphos (an environmental oestrogenic insecticide) formulation (Ekalux 25 E.C)-induced damage of the testicular tissues and antioxidant defense systems in Sprague-Dawley albino rats. J Appl Toxicol 20:197-204 (Pubitemid 30234906)
17. Carreau S, Lambard S, Delalande C, Denis-Galeraud I, Bilinska B, Bourguiba S (2003) Aromatase expression and role of estrogens in male gonads: a review. Reprod Biol Endocrinol 1:35-40
18. Prokai L, Prokai-Tatrai K, Perjési P, Simpkins JW (2006) Mechanistic insights into the direct antioxidant effects of estrogens. Drug Dev Res 66:118-125 (Pubitemid 43363965)
19. Vina J, Borras C, Gomez-Cabrera MC, Orr WC (2006) Part of the series: from dietary antioxidants to regulators in cellular signalling and gene expression. Role of reactive oxygen species and (phyto) oestrogens in the modulation of adaptive response to stress. Free Radic Res 40:111-119 (Pubitemid 43050872)
20. ShinyashikiM,KumagaiY, Nakajima H, Nagafune J, Homma-Takeda S, Sagai M, ShimojoN(1998)Differential changes in rat brain nitric oxide synthase in vivo and in vitro by methylmercury. Brain Res 798:147-155 (Pubitemid 28342030)
21. Yokoi K, Uthus EO, Nielsen FH (2003) Nickel deficiency diminishes sperm quantity and movement in rats. Biol Trace Elem Res 93:141-153 (Pubitemid 36920875)
22. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193:265-275
23. Essterbauer H, Gebicki J, Puhl H, Jurgens G (1992) The role of lipid peroxidation and antioxidants in oxidative modification of LDL. Free Radic Biol Med 13:341
24. Asada K, Takahashi M, Nagate M (1974) Assay and inhibitors of spinach superoxide dismutase.Agric. Biol Chem 38:471-473
25. Aebi H (ed) (1974) Methods of enzymatic analysis. HU Bergmeyer Academic Press, New York
26. Flohe L, Gunzler WA (1984) Analysis of glutathione peroxidase. Methods Enzymol 105:114-121
27. Arti KS, Amita GK, Peter F, Mandava VR (1996) Reversible effects of mercuric chloride on reproductive organs of the male mouse. Reprod Toxicol 10:153-159
28. Mohamed MK, Burbacher TM, Mottet NK (1987) Effects of methyl mercury on testicular functions in Macaca fascicularis monkeys. Pharmacol Toxicol 60:29-36 (Pubitemid 17042682)
29. Pectasides D, Pectasides M, Farmakis D, Nikolaou M, Koumpou M, Kostopoulou V, Mylonakis N (2004) Testicular function in patients with testicular cancer treated with bleomycin-etoposide-carboplatin (BEC90) combination chemotherapy. Eur Urol 45:187-193 (Pubitemid 38147825)
30. Turner TT, Jones CE, Howards SS, Ewing LL, Zegeye B, Gunsalus GL (1984) On the androgen microenvironment of maturing spermatozoa. Endocrinol 115:1925-1932 (Pubitemid 15206616)
31. Maddoks S, Sharpe RM (1998) Interstitial fluid volume in the rat testis: androgen-dependent regulation by the seminierous tubules? J Endocrinol 120:215-228
32. Bergh A, Damber JE, Widmark A (1990) A physiological increase in LH may influence vascular permeability in the rat testis. J Reprod Fertil 89:23-31 (Pubitemid 20156201)
33. Sharpe RM, Bartlett JM, Allenby G (1991) Evidence for the control of testicular interstitial fluid volume in the rat by specific gem cell types. J Endocrinol 128:359-367
34. Homma-Takeda S, Kugenuma Y, Iwamuro T, Kumagai Y, Shimojo N (2001) Impairment of spermatogenesis in rats by methylmercury: involvement of stage- and cell-specific germ cell apoptosis. Toxicol 169:25-35 (Pubitemid 33033315)
35. Carreau S (2001) L'aromatase testiculaire. Reprod Hum Horm 8:553-560 (Pubitemid 33097829)
36. Carreau S (2003) Estrogens-male hormones? Folia Histochem Cytobiol 41:107-111
37. Carreau S, Genissel C, Bilinska B, Levallet J (1999) Sources of oestrogen in the testis and reproductive tract of the male. Int J Androl 22:211-223 (Pubitemid 29361234)
38. Janulis L, Bahr JM, Hess RA, Janssen S, Osawa Y, Bunick D (1998) Rat testicular germ cells and epididymal sperm contain active P450 aromatase. J Androl 19:65-71 (Pubitemid 28090861)
39. Luu-The V, Zhang Y, Poirier D, Labrie F (1995) Characteristics of human types 1, 2 and 3 17 betahydroxysteroid dehydrogenase activities: oxidation/reduction and inhibition. J Steroid Biochem Mol Biol 55:581-587 (Pubitemid 26019342)
40. Mindnich R, Deluca D, Adamski J (2004) Identification and characterization of 17beta-hydroxysteroid dehydrogenases in the zebrafish, Danio rerio. Mol Cell Endocrinol 215:19-30 (Pubitemid 38333239)
41. Oliveira M, Santos MA, Pacheco M (2004) glutathione protects heavy metal-induced inhibition of hpatic microsomal ethoxyresrufin O-dethylase activity in Dicentrarchus labrx L. Ecotoxicol Environ Saf 58:379-385 (Pubitemid 38833688)
42. Hornsby PJ (1980) J Biol Chem 255:4020-4027
43. Sanocka D, Kurpisz M (2004) Reactive oxygen species and sperm cells. Reprod Biol Endocrinol 2:1-7
44. Seppanen K, Soininen P, Salonen JT, Lotjonen S, Laatikainen R (2004) Does mercury promote lipid peroxidation? An in vitro study concerning mercury, copper, and iron in eroxidation of low-density lipoprotein. Biol Trace Elem Res 101:117-132 (Pubitemid 39578287)
45. Georgellis A, Tsirigotis M, Rydstrom J (1988) Generation of superoxide anion and lipid peroxidation in different cell types and subcellular fractions from rat testis. Toxicol Appl Pharmacol 94:362-373
46. Favier A (2003) Le stress oxydant : Intérět conceptuel et expérimental dans la compréhension des mécanismes des maladies et potentiel thérapeutique. L'actualité chimique 105-115
47. Sharma MK, Sharma A, Kumar A, Kumar M (2007) Spirulina fusiformis provides protection against mercuric chloride induced oxidative stress in Swiss albino mice. Food Chem Toxicol 45:2412-2419 (Pubitemid 47600450)
48. Hornsby PJ, Crivello JF (1983) The role of lipid peroxidation and biological antioxidants in the function of the adrenal cortex I: a background review. Mol Cell Endocrinol 30:1-20 (Pubitemid 13111068)
49. Borr?s C, Gambini J, G?mez-Cabrera MC, Sastre J, Pallard? FV, Mann GE, Vi?a J (2005) 17β- oestradiol up-regulates longevity-related, antioxidant enzyme expression via the ERK1 and ERK2[MAPK]/NF?B cascade. Aging Cell 4:113-118 (Pubitemid 41602744)