메뉴 건너뛰기




Volumn 232, Issue 2, 2007, Pages 323-335

Iron and copper toxicity in diseases of aging, particularly atherosclerosis and Alzheimer's disease

Author keywords

Alzheimer's disease; Atherosclerosis; Copper; Iron

Indexed keywords

COPPER; IRON; REACTIVE OXYGEN METABOLITE;

EID: 33846782816     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (195)

References (136)
  • 1
    • 0033941827 scopus 로고    scopus 로고
    • Association of age, sex, and race with body iron stores in adults: Analysis of NHANES III data
    • Zacharski LR, Ornstein DL, Woloshin S, Schwartz LM. Association of age, sex, and race with body iron stores in adults: analysis of NHANES III data. Am Heart J 140:98-104, 2000.
    • (2000) Am Heart J , vol.140 , pp. 98-104
    • Zacharski, L.R.1    Ornstein, D.L.2    Woloshin, S.3    Schwartz, L.M.4
  • 2
    • 77049308856 scopus 로고
    • Aging: A theory based on free radical and radiation chemistry
    • Harman D. Aging: a theory based on free radical and radiation chemistry. J Gerontol 11:298-300, 1956.
    • (1956) J Gerontol , vol.11 , pp. 298-300
    • Harman, D.1
  • 3
    • 0014558234 scopus 로고
    • Prolongation of life: Role of free radical reactions in aging
    • Harman D. Prolongation of life: role of free radical reactions in aging. J Am Geriatr Soc 17:721-735, 1969.
    • (1969) J Am Geriatr Soc , vol.17 , pp. 721-735
    • Harman, D.1
  • 5
    • 0036591849 scopus 로고    scopus 로고
    • Lipid peroxidation and protein oxidation in Alzheimer's disease brain: Potential causes and consequences involving amyloid beta-peptide-associated free radical oxidative stress
    • Butterfield DA, Lauderback CM. Lipid peroxidation and protein oxidation in Alzheimer's disease brain: potential causes and consequences involving amyloid beta-peptide-associated free radical oxidative stress. Free Radic Biol Med 32:1050-1060, 2002.
    • (2002) Free Radic Biol Med , vol.32 , pp. 1050-1060
    • Butterfield, D.A.1    Lauderback, C.M.2
  • 6
    • 0035880007 scopus 로고    scopus 로고
    • Brain protein oxidation in age-related neurodegenerative disorders that are associated with aggregated proteins
    • Butterfield DA, Kanski J. Brain protein oxidation in age-related neurodegenerative disorders that are associated with aggregated proteins. Mech Ageing Dev 122:945-962, 2001.
    • (2001) Mech Ageing Dev , vol.122 , pp. 945-962
    • Butterfield, D.A.1    Kanski, J.2
  • 7
    • 8744276616 scopus 로고    scopus 로고
    • Amyloid beta-peptide(1-42) contributes to the oxidative stress and neurodegeneration found in Alzheimer disease brain
    • Butterfield DA, Boyd-Kimball D. Amyloid beta-peptide(1-42) contributes to the oxidative stress and neurodegeneration found in Alzheimer disease brain. Brain Pathol 14:426-432, 2004.
    • (2004) Brain Pathol , vol.14 , pp. 426-432
    • Butterfield, D.A.1    Boyd-Kimball, D.2
  • 8
    • 1842505677 scopus 로고    scopus 로고
    • Proteomics: A new approach to investigate oxidative stress in Alzheimer's disease brain
    • Butterfield DA. Proteomics: a new approach to investigate oxidative stress in Alzheimer's disease brain. Brain Res 1000:1-7, 2004.
    • (2004) Brain Res , vol.1000 , pp. 1-7
    • Butterfield, D.A.1
  • 11
    • 0642368399 scopus 로고    scopus 로고
    • High serum ferritin is not identical to high iron stores [comment]
    • Hallberg L, Hulthen L. High serum ferritin is not identical to high iron stores [comment]. Am J Clin Nutr 78:1225-1226, 2003.
    • (2003) Am J Clin Nutr , vol.78 , pp. 1225-1226
    • Hallberg, L.1    Hulthen, L.2
  • 12
    • 0036569986 scopus 로고    scopus 로고
    • Molecular bases of cellular iron toxicity
    • Eaton JW, Qian M. Molecular bases of cellular iron toxicity. Free Radic Biol Med 32:833-840, 2002.
    • (2002) Free Radic Biol Med , vol.32 , pp. 833-840
    • Eaton, J.W.1    Qian, M.2
  • 13
    • 0142200240 scopus 로고    scopus 로고
    • Iron as the malignant spirit in successful ageing
    • Polla AS, Polla LL, Polla BS. Iron as the malignant spirit in successful ageing. Ageing Res Rev 2:25-37, 2003.
    • (2003) Ageing Res Rev , vol.2 , pp. 25-37
    • Polla, A.S.1    Polla, L.L.2    Polla, B.S.3
  • 14
    • 1242340476 scopus 로고    scopus 로고
    • Iron and peripheral arterial disease: Revisiting the iron hypothesis in a different light [see comment]
    • Ramakrishna G, Rooke TW, Cooper LT. Iron and peripheral arterial disease: revisiting the iron hypothesis in a different light [see comment]. Vasc Med 8:203-210, 2003.
    • (2003) Vasc Med , vol.8 , pp. 203-210
    • Ramakrishna, G.1    Rooke, T.W.2    Cooper, L.T.3
  • 15
    • 3042658542 scopus 로고    scopus 로고
    • Brain iron deposition and the free radical-mitochondrial theory of ageing
    • Schipper HM. Brain iron deposition and the free radical-mitochondrial theory of ageing. Ageing Res Rev 3:265-301, 2004.
    • (2004) Ageing Res Rev , vol.3 , pp. 265-301
    • Schipper, H.M.1
  • 16
    • 0019434645 scopus 로고
    • Iron and the sex difference in heart disease risk
    • Sullivan JL. Iron and the sex difference in heart disease risk. Lancet 1: 1293-1294, 1981.
    • (1981) Lancet 1 , vol.1293-1294
    • Sullivan, J.L.1
  • 17
    • 0037326156 scopus 로고    scopus 로고
    • Are menstruating women protected from heart disease because of, or in spite of, estrogen? Relevance to the iron hypothesis
    • Sullivan JL. Are menstruating women protected from heart disease because of, or in spite of, estrogen? Relevance to the iron hypothesis. Am Heart J 145:190-194, 2003.
    • (2003) Am Heart J , vol.145 , pp. 190-194
    • Sullivan, J.L.1
  • 18
    • 10944231116 scopus 로고    scopus 로고
    • Is stored iron safe?
    • Sullivan JL. Is stored iron safe? J Lab Clin Med 144:280-284, 2004.
    • (2004) J Lab Clin Med , vol.144 , pp. 280-284
    • Sullivan, J.L.1
  • 20
  • 22
    • 0032547326 scopus 로고    scopus 로고
    • Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group [see comment]
    • Hulley S, Grady D, Bush T, Furberg C, Herrington D, Riggs B, Vittinghoff E. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group [see comment]. JAMA 280:605-613, 1998.
    • (1998) JAMA , vol.280 , pp. 605-613
    • Hulley, S.1    Grady, D.2    Bush, T.3    Furberg, C.4    Herrington, D.5    Riggs, B.6    Vittinghoff, E.7
  • 23
    • 20444452107 scopus 로고    scopus 로고
    • Ferritin in atherosclerosis
    • You SA, Wang Q. Ferritin in atherosclerosis. Clin Chim Acta 357:1-16, 2005.
    • (2005) Clin Chim Acta , vol.357 , pp. 1-16
    • You, S.A.1    Wang, Q.2
  • 24
    • 1642319251 scopus 로고    scopus 로고
    • Serum markers of stored body iron are not appropriate markers of health effects of iron: A focus on serum ferritin
    • Lee DH, Jacobs DR. Serum markers of stored body iron are not appropriate markers of health effects of iron: a focus on serum ferritin. Med Hypotheses 62:442-445, 2004.
    • (2004) Med Hypotheses , vol.62 , pp. 442-445
    • Lee, D.H.1    Jacobs, D.R.2
  • 27
    • 0033848148 scopus 로고    scopus 로고
    • The iron hypothesis: Does iron play a role in atherosclerosis?
    • Meyers DG. The iron hypothesis: does iron play a role in atherosclerosis? Transfusion 40:1023-1029, 2000.
    • (2000) Transfusion , vol.40 , pp. 1023-1029
    • Meyers, D.G.1
  • 28
    • 0026649212 scopus 로고
    • Stimulation of lipid peroxidation and hydroxyl-radical generation by the contents of human atherosclerotic lesions
    • Smith C, Mitchinson MJ, Aruoma OI, Halliwell B. Stimulation of lipid peroxidation and hydroxyl-radical generation by the contents of human atherosclerotic lesions. Biochem J 286:901-905, 1992.
    • (1992) Biochem J , vol.286 , pp. 901-905
    • Smith, C.1    Mitchinson, M.J.2    Aruoma, O.I.3    Halliwell, B.4
  • 29
    • 0003714337 scopus 로고    scopus 로고
    • Elemental changes in atherosclerotic lesions using nuclear microscopy
    • Thong PS, Selley M, Watt F. Elemental changes in atherosclerotic lesions using nuclear microscopy. Cell Mol Biol (Noisy-le-grand) 42: 103-110, 1996.
    • (1996) Cell Mol Biol (Noisy-le-grand) , vol.42 , pp. 103-110
    • Thong, P.S.1    Selley, M.2    Watt, F.3
  • 30
    • 0027946340 scopus 로고
    • Concentration of copper, zinc, chromium, iron and nickel in the abdominal aorta of patients deceased with coronary heart disease
    • Vlad M, Caseanu E, Uza G, Petrescu M. Concentration of copper, zinc, chromium, iron and nickel in the abdominal aorta of patients deceased with coronary heart disease. J Trace Elem Electrolytes Health Dis 8:111-114, 1994.
    • (1994) J Trace Elem Electrolytes Health Dis , vol.8 , pp. 111-114
    • Vlad, M.1    Caseanu, E.2    Uza, G.3    Petrescu, M.4
  • 31
    • 0029095698 scopus 로고
    • Prooxidant iron and copper, with ferroxidase and xanthine oxidase activities in human atherosclerotic material
    • Swain J, Gutteridge JM. Prooxidant iron and copper, with ferroxidase and xanthine oxidase activities in human atherosclerotic material. FEBS Lett 368:513-515, 1995.
    • (1995) FEBS Lett , vol.368 , pp. 513-515
    • Swain, J.1    Gutteridge, J.M.2
  • 32
    • 2442563696 scopus 로고    scopus 로고
    • Direct detection and quantification of transition metal ions in human atherosclerotic plaques: Evidence for the presence of elevated levels of iron and copper
    • Stadler N, Lindner RA, Davies MJ. Direct detection and quantification of transition metal ions in human atherosclerotic plaques: evidence for the presence of elevated levels of iron and copper. Arterioscler Thromb Vasc Biol 24:949-954, 2004.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 949-954
    • Stadler, N.1    Lindner, R.A.2    Davies, M.J.3
  • 34
    • 0032102148 scopus 로고    scopus 로고
    • Colocalization of iron and ceroid in human atherosclerotic lesions
    • Lee FY, Lee TS, Pan CC, Huang AL, Chau LY. Colocalization of iron and ceroid in human atherosclerotic lesions. Atherosclerosis 138:281-288, 1998.
    • (1998) Atherosclerosis , vol.138 , pp. 281-288
    • Lee, F.Y.1    Lee, T.S.2    Pan, C.C.3    Huang, A.L.4    Chau, L.Y.5
  • 35
    • 0029941609 scopus 로고    scopus 로고
    • Yuan XM, Anders WL, Olsson AG, Brunk UT. Iron in human atheroma and LDL oxidation by macrophages following erythrophagocytosis. Atherosclerosis 124:61-73, 1996.
    • Yuan XM, Anders WL, Olsson AG, Brunk UT. Iron in human atheroma and LDL oxidation by macrophages following erythrophagocytosis. Atherosclerosis 124:61-73, 1996.
  • 36
    • 3242780850 scopus 로고    scopus 로고
    • The role of labile iron pool in cardiovascular diseases
    • Kruszewski M. The role of labile iron pool in cardiovascular diseases. Acta Biochim Pol 51:471-480, 2004.
    • (2004) Acta Biochim Pol , vol.51 , pp. 471-480
    • Kruszewski, M.1
  • 37
    • 0141526416 scopus 로고    scopus 로고
    • Serum ferritin concentration is associated with plasma levels of cholesterol oxidation products in man
    • Tuomainen TP, Diczfalusy U, Kaikkonen J, Nyyssonen K, Salonen JT. Serum ferritin concentration is associated with plasma levels of cholesterol oxidation products in man. Free Radic Biol Med 35:922-928, 2003.
    • (2003) Free Radic Biol Med , vol.35 , pp. 922-928
    • Tuomainen, T.P.1    Diczfalusy, U.2    Kaikkonen, J.3    Nyyssonen, K.4    Salonen, J.T.5
  • 38
    • 0028092229 scopus 로고
    • Homocysteine induces iron-catalyzed lipid peroxidation of low-density lipoprotein that is prevented by alpha-tocopherol
    • Hirano K, Ogihara T, Miki M, Yasuda H, Tamai H, Kawamura N, Mino M. Homocysteine induces iron-catalyzed lipid peroxidation of low-density lipoprotein that is prevented by alpha-tocopherol. Free Radic Res 21:267-276, 1994.
    • (1994) Free Radic Res , vol.21 , pp. 267-276
    • Hirano, K.1    Ogihara, T.2    Miki, M.3    Yasuda, H.4    Tamai, H.5    Kawamura, N.6    Mino, M.7
  • 41
    • 0033592398 scopus 로고    scopus 로고
    • Increased risk of acute myocardial infarction in carriers of the hemochromatosis gene Cys282Tyr mutation : A prospective cohort study in men in eastern Finland [see comment]
    • Tuomainen TP, Kontula K, Nyyssonen K, Lakka TA, Helio T, Salonen JT. Increased risk of acute myocardial infarction in carriers of the hemochromatosis gene Cys282Tyr mutation : a prospective cohort study in men in eastern Finland [see comment]. Circulation 100:1274-1279, 1999.
    • (1999) Circulation , vol.100 , pp. 1274-1279
    • Tuomainen, T.P.1    Kontula, K.2    Nyyssonen, K.3    Lakka, T.A.4    Helio, T.5    Salonen, J.T.6
  • 43
    • 0033840089 scopus 로고    scopus 로고
    • Iron overload and atherosclerosis [comment]
    • Niederau C. Iron overload and atherosclerosis [comment]. Hepatology 32:672-674, 2000.
    • (2000) Hepatology , vol.32 , pp. 672-674
    • Niederau, C.1
  • 49
    • 1842608817 scopus 로고    scopus 로고
    • Iron, atherosclerosis, and neurodegeneration: A key role for cholesterol in promoting iron-dependent oxidative damage?
    • Ong WY, Halliwell B. Iron, atherosclerosis, and neurodegeneration: a key role for cholesterol in promoting iron-dependent oxidative damage? Ann N Y Acad Sci 1012:51-64, 2004.
    • (2004) Ann N Y Acad Sci , vol.1012 , pp. 51-64
    • Ong, W.Y.1    Halliwell, B.2
  • 51
  • 53
    • 0031467468 scopus 로고    scopus 로고
    • Namekata K, Imagawa M, Terashi A, Ohta S, Oyama F, Ihara Y. Association of transferrin C2 allele with late-onset Alzheimer's disease. Hum Genet 101:126-129, 1997.
    • Namekata K, Imagawa M, Terashi A, Ohta S, Oyama F, Ihara Y. Association of transferrin C2 allele with late-onset Alzheimer's disease. Hum Genet 101:126-129, 1997.
  • 56
    • 2442482592 scopus 로고    scopus 로고
    • Free radicals: Key to brain aging and heme oxygenase as a cellular response to oxidative stress
    • Poon HF, Calabrese V, Scapagnini G, Butterfield DA. Free radicals: key to brain aging and heme oxygenase as a cellular response to oxidative stress. J Gerontol A Biol Sci Med Sci 59:478-493, 2004.
    • (2004) J Gerontol A Biol Sci Med Sci , vol.59 , pp. 478-493
    • Poon, H.F.1    Calabrese, V.2    Scapagnini, G.3    Butterfield, D.A.4
  • 57
    • 3042613609 scopus 로고    scopus 로고
    • Heme, iron, and the mitochondrial decay of ageing
    • Atamna H. Heme, iron, and the mitochondrial decay of ageing. Ageing Res Rev 3:303-318, 2004.
    • (2004) Ageing Res Rev , vol.3 , pp. 303-318
    • Atamna, H.1
  • 58
    • 0027316214 scopus 로고
    • Inhibition of iron absorption prolongs the life span of Drosophila
    • Massie HR, Aiello VR, Williams TR. Inhibition of iron absorption prolongs the life span of Drosophila. Mech Ageing Dev 67:227-237, 1993.
    • (1993) Mech Ageing Dev , vol.67 , pp. 227-237
    • Massie, H.R.1    Aiello, V.R.2    Williams, T.R.3
  • 59
    • 0021319893 scopus 로고
    • Effects of diethyldithiocarbamate on life span, metabolic rate, superoxide dismutase, catalase, inorganic peroxides and glutathione in the adult male housefly, Musca domestica
    • Sohal RS, Farmer KJ, Allen RG, Ragland SS. Effects of diethyldithiocarbamate on life span, metabolic rate, superoxide dismutase, catalase, inorganic peroxides and glutathione in the adult male housefly, Musca domestica. Mech Ageing Dev 24:175-183, 1984.
    • (1984) Mech Ageing Dev , vol.24 , pp. 175-183
    • Sohal, R.S.1    Farmer, K.J.2    Allen, R.G.3    Ragland, S.S.4
  • 60
    • 2942631560 scopus 로고    scopus 로고
    • Elevated serum transferrin saturation and mortality
    • Mainous AG, Gill JM, Carek PJ. Elevated serum transferrin saturation and mortality. Ann Fam Med 2:133-138, 2004.
    • (2004) Ann Fam Med , vol.2 , pp. 133-138
    • Mainous, A.G.1    Gill, J.M.2    Carek, P.J.3
  • 61
    • 2942633772 scopus 로고    scopus 로고
    • The mortality risk of elevated serum transferrin saturation and consumption of dietary iron
    • Mainous AG, Wells B, Carek PJ, Gill JM, Geesey ME. The mortality risk of elevated serum transferrin saturation and consumption of dietary iron. Ann Fam Med 2:139-144, 2004.
    • (2004) Ann Fam Med , vol.2 , pp. 139-144
    • Mainous, A.G.1    Wells, B.2    Carek, P.J.3    Gill, J.M.4    Geesey, M.E.5
  • 62
    • 77049111333 scopus 로고    scopus 로고
    • Normal copper metabolism and lowering copper to subnormal levels for therapeutic purposes
    • Benhamou JP, Rizzetto M, Reichen J, Rodés J, Blei A, Eds, Oxford, England: Blackwell Publishing, Expected publication
    • Brewer GJ, Harris ED, Askari FK. Normal copper metabolism and lowering copper to subnormal levels for therapeutic purposes. In: Benhamou JP, Rizzetto M, Reichen J, Rodés J, Blei A, Eds. Textbook of Hepatology: From basic science to clinical practice. Oxford, England: Blackwell Publishing, Expected publication, 2006.
    • (2006) Textbook of Hepatology: From basic science to clinical practice
    • Brewer, G.J.1    Harris, E.D.2    Askari, F.K.3
  • 63
    • 0041920560 scopus 로고    scopus 로고
    • Myelopolyneuropathy and pancytopenia due to copper deficiency and high zinc levels of unknown origin: Further support for existence of a new zinc overload syndrome
    • Hedera P, Fink JK, Bockenstedt PL, Brewer GJ. Myelopolyneuropathy and pancytopenia due to copper deficiency and high zinc levels of unknown origin: further support for existence of a new zinc overload syndrome. Arch Neurol 60:1303-1306, 2003.
    • (2003) Arch Neurol , vol.60 , pp. 1303-1306
    • Hedera, P.1    Fink, J.K.2    Bockenstedt, P.L.3    Brewer, G.J.4
  • 64
    • 0026513619 scopus 로고
    • Trace element status in healthy subjects switching from a mixed to a lactovegetarian diet for 12 mo
    • Srikumar TS, Johansson GK, Ockerman PA, Gustafsson JA, Akesson B. Trace element status in healthy subjects switching from a mixed to a lactovegetarian diet for 12 mo. Am J Clin Nutr 55:885-890, 1992.
    • (1992) Am J Clin Nutr , vol.55 , pp. 885-890
    • Srikumar, T.S.1    Johansson, G.K.2    Ockerman, P.A.3    Gustafsson, J.A.4    Akesson, B.5
  • 67
    • 0028267292 scopus 로고
    • Intact human ceruloplasmin oxidatively modifies low density lipoprotein
    • Ehrenwald E, Chisolm GM, Fox PL. Intact human ceruloplasmin oxidatively modifies low density lipoprotein. J Clin Invest 93:1493-1501, 1994.
    • (1994) J Clin Invest , vol.93 , pp. 1493-1501
    • Ehrenwald, E.1    Chisolm, G.M.2    Fox, P.L.3
  • 68
    • 0030851818 scopus 로고    scopus 로고
    • Identification of the prooxidant site of human ceruloplasmin: A model for oxidative damage by copper bound to protein surfaces
    • Mukhopadhyay CK, Mazumder B, Lindley PF, Fox PL. Identification of the prooxidant site of human ceruloplasmin: a model for oxidative damage by copper bound to protein surfaces. Proc Natl Acad Sci U S A 94:11546-11551, 1997.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 11546-11551
    • Mukhopadhyay, C.K.1    Mazumder, B.2    Lindley, P.F.3    Fox, P.L.4
  • 73
    • 0031033243 scopus 로고    scopus 로고
    • Epidemiologic study of trace elements and magnesium on risk of coronary artery disease in rural and urban Indian populations
    • Singh RB, Gupta UC, Mittal N, Niaz MA, Ghosh S, Rastogi V. Epidemiologic study of trace elements and magnesium on risk of coronary artery disease in rural and urban Indian populations. J Am Coll Nutr 16:62-67, 1997.
    • (1997) J Am Coll Nutr , vol.16 , pp. 62-67
    • Singh, R.B.1    Gupta, U.C.2    Mittal, N.3    Niaz, M.A.4    Ghosh, S.5    Rastogi, V.6
  • 74
    • 0025870212 scopus 로고
    • Interactions of serum copper, selenium, and low density lipoprotein cholesterol in atherogenesis
    • Salonen JT, Salonen R, Seppanen K, Kantola M, Suntioinen S, Korpela H. Interactions of serum copper, selenium, and low density lipoprotein cholesterol in atherogenesis. BMJ 302:756-760, 1991.
    • (1991) BMJ , vol.302 , pp. 756-760
    • Salonen, J.T.1    Salonen, R.2    Seppanen, K.3    Kantola, M.4    Suntioinen, S.5    Korpela, H.6
  • 75
    • 0033936128 scopus 로고    scopus 로고
    • Serum copper concentration and coronary heart disease among US adults
    • Ford ES. Serum copper concentration and coronary heart disease among US adults. Am J Epidemiol 151:1182-1188, 2000.
    • (2000) Am J Epidemiol , vol.151 , pp. 1182-1188
    • Ford, E.S.1
  • 79
    • 0029084859 scopus 로고
    • Elevated plasma ceruloplasmin in insulin-dependent diabetes mellitus: Evidence for increased oxidative stress as a variable complication
    • Cunningham J, Leffell M, Mearkle P, Harmatz P. Elevated plasma ceruloplasmin in insulin-dependent diabetes mellitus: evidence for increased oxidative stress as a variable complication. Metabolism 44: 996-999, 1995.
    • (1995) Metabolism , vol.44 , pp. 996-999
    • Cunningham, J.1    Leffell, M.2    Mearkle, P.3    Harmatz, P.4
  • 80
    • 0023199095 scopus 로고
    • Acute phase proteins in patients with abdominal aortic aneurysms
    • Powell JT, Muller BR, Greenhalgh RM. Acute phase proteins in patients with abdominal aortic aneurysms. J Cardiovasc Surg 28:528-530, 1987.
    • (1987) J Cardiovasc Surg , vol.28 , pp. 528-530
    • Powell, J.T.1    Muller, B.R.2    Greenhalgh, R.M.3
  • 81
    • 0026747821 scopus 로고
    • Antioxidant status in relation to free radical production during stable and unstable anginal syndromes
    • Jayakumari N, Ambikakumari V, Balakrishnan KG, Iyer KS. Antioxidant status in relation to free radical production during stable and unstable anginal syndromes. Atherosclerosis 94:183-190, 1992.
    • (1992) Atherosclerosis , vol.94 , pp. 183-190
    • Jayakumari, N.1    Ambikakumari, V.2    Balakrishnan, K.G.3    Iyer, K.S.4
  • 83
    • 0034814441 scopus 로고    scopus 로고
    • The activity of cholesterol esterase and ceruloplasmin are inversely related in the serum of men with atherosclerosis obliterans
    • Piorunska-Stolzmann M, Iskra M, Majewski W. The activity of cholesterol esterase and ceruloplasmin are inversely related in the serum of men with atherosclerosis obliterans. Med Sci Monit 7:940-945, 2001.
    • (2001) Med Sci Monit , vol.7 , pp. 940-945
    • Piorunska-Stolzmann, M.1    Iskra, M.2    Majewski, W.3
  • 84
    • 0030956673 scopus 로고    scopus 로고
    • Ridker PM, Cushman M, Stampfer MJ, Tracy RP, Hennekens CH. Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men [see comment][erratum appears in N Engl J Med 337:356, 1997]. N Engl J Med 336:973-979, 1997.
    • Ridker PM, Cushman M, Stampfer MJ, Tracy RP, Hennekens CH. Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men [see comment][erratum appears in N Engl J Med 337:356, 1997]. N Engl J Med 336:973-979, 1997.
  • 85
    • 0019417261 scopus 로고
    • Magnesium and trace metals: Risk factors for coronary heart disease? Association between blood levels and angiographic findings
    • Manthey J, Stoeppler M, Morgenstern W, Nussel E, Opherk D, Weintraut A, Wesch H, Kubler W. Magnesium and trace metals: risk factors for coronary heart disease? Association between blood levels and angiographic findings. Circulation 64:722-729, 1981.
    • (1981) Circulation , vol.64 , pp. 722-729
    • Manthey, J.1    Stoeppler, M.2    Morgenstern, W.3    Nussel, E.4    Opherk, D.5    Weintraut, A.6    Wesch, H.7    Kubler, W.8
  • 89
    • 0036655736 scopus 로고    scopus 로고
    • Neointima formation in the rat carotid artery is exacerbated by dietary copper deficiency
    • Dalle Lucca JJ, Saari JT, Falcone JC, Schuschke DA. Neointima formation in the rat carotid artery is exacerbated by dietary copper deficiency. Exp Biol Med (Maywood) 227:487-491, 2002.
    • (2002) Exp Biol Med (Maywood) , vol.227 , pp. 487-491
    • Dalle Lucca, J.J.1    Saari, J.T.2    Falcone, J.C.3    Schuschke, D.A.4
  • 90
    • 0032733673 scopus 로고    scopus 로고
    • Cardiovascular effects of dietary copper deficiency
    • Saari JT, Schuschke DA. Cardiovascular effects of dietary copper deficiency. Biofactors 10:359-375, 1999.
    • (1999) Biofactors , vol.10 , pp. 359-375
    • Saari, J.T.1    Schuschke, D.A.2
  • 91
    • 0036801785 scopus 로고    scopus 로고
    • Effect of dietary copper supplementation on cell composition and apoptosis in atherosclerotic lesions of cholesterol-fed rabbits
    • Lamb DJ, Avades TY, Allen MD, Anwar K, Kass GE, Ferns GA. Effect of dietary copper supplementation on cell composition and apoptosis in atherosclerotic lesions of cholesterol-fed rabbits. Atherosclerosis 164:229-236, 2002.
    • (2002) Atherosclerosis , vol.164 , pp. 229-236
    • Lamb, D.J.1    Avades, T.Y.2    Allen, M.D.3    Anwar, K.4    Kass, G.E.5    Ferns, G.A.6
  • 92
    • 0032803929 scopus 로고    scopus 로고
    • Dietary copper supplementation reduces atherosclerosis in the cholesterol-fed rabbit
    • Lamb DJ, Reeves GL, Taylor A, Ferns GA. Dietary copper supplementation reduces atherosclerosis in the cholesterol-fed rabbit. Atherosclerosis 146:33-43, 1999.
    • (1999) Atherosclerosis , vol.146 , pp. 33-43
    • Lamb, D.J.1    Reeves, G.L.2    Taylor, A.3    Ferns, G.A.4
  • 93
    • 0035569361 scopus 로고    scopus 로고
    • Biphasic modulation of atherosclerosis induced by graded dietary copper supplementation in the cholesterol-fed rabbit
    • Lamb DJ, Avades TY, Ferns GA. Biphasic modulation of atherosclerosis induced by graded dietary copper supplementation in the cholesterol-fed rabbit. Int J Exp Pathol 82:287-294, 2001.
    • (2001) Int J Exp Pathol , vol.82 , pp. 287-294
    • Lamb, D.J.1    Avades, T.Y.2    Ferns, G.A.3
  • 94
    • 18844375108 scopus 로고    scopus 로고
    • The receptor binding domain of apolipoprotein E is responsible for its antioxidant activity
    • Pham T, Kodvawala A, Hui DY. The receptor binding domain of apolipoprotein E is responsible for its antioxidant activity. Biochemistry 44:7577-7582, 2005.
    • (2005) Biochemistry , vol.44 , pp. 7577-7582
    • Pham, T.1    Kodvawala, A.2    Hui, D.Y.3
  • 95
    • 1642321899 scopus 로고    scopus 로고
    • Copper-mediated LDL oxidation by homocysteine and related compounds depends largely on copper ligation
    • Nakano E, Williamson MP, Williams NH, Powers HJ. Copper-mediated LDL oxidation by homocysteine and related compounds depends largely on copper ligation. Biochim Biophys Acta 1688:33-42, 2004.
    • (2004) Biochim Biophys Acta , vol.1688 , pp. 33-42
    • Nakano, E.1    Williamson, M.P.2    Williams, N.H.3    Powers, H.J.4
  • 97
    • 0022552919 scopus 로고
    • Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine
    • Starkebaum G, Harlan JM. Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine. J Clin Invest 77:1370-1376, 1986.
    • (1986) J Clin Invest , vol.77 , pp. 1370-1376
    • Starkebaum, G.1    Harlan, J.M.2
  • 98
    • 0030801910 scopus 로고    scopus 로고
    • The cell-damaging effects of low amounts of homocysteine and copper ions in human cell line cultures are caused by oxidative stress
    • Hultberg B, Andersson A, Isaksson A. The cell-damaging effects of low amounts of homocysteine and copper ions in human cell line cultures are caused by oxidative stress. Toxicology 123:33-40, 1997.
    • (1997) Toxicology , vol.123 , pp. 33-40
    • Hultberg, B.1    Andersson, A.2    Isaksson, A.3
  • 99
    • 0009715206 scopus 로고    scopus 로고
    • Investigation of the inhibitory effects of homocysteine and copper on nitric oxide-mediated relaxation of rat isolated aorta
    • Emsley AM, Jeremy JY, Gomes GN, Angelini GD, Plane F. Investigation of the inhibitory effects of homocysteine and copper on nitric oxide-mediated relaxation of rat isolated aorta. Br J Pharmacol 126:1034-1040, 1999.
    • (1999) Br J Pharmacol , vol.126 , pp. 1034-1040
    • Emsley, A.M.1    Jeremy, J.Y.2    Gomes, G.N.3    Angelini, G.D.4    Plane, F.5
  • 100
    • 0031021944 scopus 로고    scopus 로고
    • Mass spectrometric quantification of markers for protein oxidation by tyrosyl radical, copper, and hydroxyl radical in low density lipoprotein isolated from human atherosclerotic plaques
    • Leeuwenburgh C, Rasmussen JE, Hsu FF, Mueller DM, Pennathur S, Heinecke JW. Mass spectrometric quantification of markers for protein oxidation by tyrosyl radical, copper, and hydroxyl radical in low density lipoprotein isolated from human atherosclerotic plaques. J Biol Chem 272:3520-3526, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 3520-3526
    • Leeuwenburgh, C.1    Rasmussen, J.E.2    Hsu, F.F.3    Mueller, D.M.4    Pennathur, S.5    Heinecke, J.W.6
  • 101
    • 0030867360 scopus 로고    scopus 로고
    • The possible role of copper ions in atherogenesis: The Blue Janus [see comment]
    • Ferns GA, Lamb DJ, Taylor A. The possible role of copper ions in atherogenesis: the Blue Janus [see comment]. Atherosclerosis 133: 139-152, 1997.
    • (1997) Atherosclerosis , vol.133 , pp. 139-152
    • Ferns, G.A.1    Lamb, D.J.2    Taylor, A.3
  • 102
  • 105
    • 14844304305 scopus 로고    scopus 로고
    • Oxidation of cholesterol by amyloid precursor protein and beta-amyloid peptide
    • Nelson TJ, Alkon DL. Oxidation of cholesterol by amyloid precursor protein and beta-amyloid peptide. J Biol Chem 280:7377-7387, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 7377-7387
    • Nelson, T.J.1    Alkon, D.L.2
  • 107
    • 0033964859 scopus 로고    scopus 로고
    • In situ oxidative catalysis by neurofibrillary tangles and senile plaques in Alzheimer's disease: A central role for bound transition metals
    • Sayre LM, Perry G, Harris PL, Liu Y, Schubert KA, Smith MA. In situ oxidative catalysis by neurofibrillary tangles and senile plaques in Alzheimer's disease: a central role for bound transition metals. J Neurochem 74:270-279, 2000.
    • (2000) J Neurochem , vol.74 , pp. 270-279
    • Sayre, L.M.1    Perry, G.2    Harris, P.L.3    Liu, Y.4    Schubert, K.A.5    Smith, M.A.6
  • 108
    • 33645407628 scopus 로고    scopus 로고
    • Copper binding properties of a tau peptide associated with Alzheimer's disease studied by CD, NMR, and MALDI-TOF MS
    • Ma Q, Li Y, Du J, Liu H, Kanazawa K, Nemoto T, Nakanishi H, Zhao Y. Copper binding properties of a tau peptide associated with Alzheimer's disease studied by CD, NMR, and MALDI-TOF MS. Peptides 27:841-849, 2006.
    • (2006) Peptides , vol.27 , pp. 841-849
    • Ma, Q.1    Li, Y.2    Du, J.3    Liu, H.4    Kanazawa, K.5    Nemoto, T.6    Nakanishi, H.7    Zhao, Y.8
  • 110
    • 0029765553 scopus 로고    scopus 로고
    • Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides
    • Miyata M, Smith JD. Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides. Nat Genet 14:55-61, 1996.
    • (1996) Nat Genet , vol.14 , pp. 55-61
    • Miyata, M.1    Smith, J.D.2
  • 116
    • 16544362951 scopus 로고    scopus 로고
    • Cholesterol, copper, and accumulation of thioflavine S-reactive Alzheimer's-like amyloid beta in rabbit brain
    • Sparks L. Cholesterol, copper, and accumulation of thioflavine S-reactive Alzheimer's-like amyloid beta in rabbit brain. J Mol Neurosci 24:97-104, 2004.
    • (2004) J Mol Neurosci , vol.24 , pp. 97-104
    • Sparks, L.1
  • 122
    • 4243704850 scopus 로고    scopus 로고
    • Interactions of copper with glycated proteins: Possible involvement in the etiology of diabetic neuropathy
    • Eaton JW, Qian M. Interactions of copper with glycated proteins: possible involvement in the etiology of diabetic neuropathy. Mol Cell Biochem 234-235:135-142, 2002.
    • (2002) Mol Cell Biochem , vol.234-235 , pp. 135-142
    • Eaton, J.W.1    Qian, M.2
  • 123
    • 0037337399 scopus 로고    scopus 로고
    • Treatment of Wilson disease with ammonium tetrathiomolybdate: III. Initial therapy in a total of 55 neurologically affected patients and follow-up with zinc therapy
    • Brewer GJ, Hedera P, Kluin KJ, Carlson M, Askari F, Dick RB, Sitterly J, Fink JK. Treatment of Wilson disease with ammonium tetrathiomolybdate: III. Initial therapy in a total of 55 neurologically affected patients and follow-up with zinc therapy. Arch Neurol 60: 379-385, 2003.
    • (2003) Arch Neurol , vol.60 , pp. 379-385
    • Brewer, G.J.1    Hedera, P.2    Kluin, K.J.3    Carlson, M.4    Askari, F.5    Dick, R.B.6    Sitterly, J.7    Fink, J.K.8
  • 124
    • 18844458093 scopus 로고    scopus 로고
    • Copper lowering therapy with tetrathiomolybdate as an antiangiogenic strategy in cancer
    • Brewer GJ. Copper lowering therapy with tetrathiomolybdate as an antiangiogenic strategy in cancer. Curr Cancer Drug Targets 5:195-202, 2005.
    • (2005) Curr Cancer Drug Targets , vol.5 , pp. 195-202
    • Brewer, G.J.1
  • 125
    • 0037342259 scopus 로고    scopus 로고
    • Tetrathiomolybdate therapy protects against bleomycin-induced pulmonary fibrosis in mice
    • Brewer GJ, Ullenbruch MR, Dick RB, Olivarez L, Phan SH. Tetrathiomolybdate therapy protects against bleomycin-induced pulmonary fibrosis in mice. J Lab Clin Med 141:210-216, 2003.
    • (2003) J Lab Clin Med , vol.141 , pp. 210-216
    • Brewer, G.J.1    Ullenbruch, M.R.2    Dick, R.B.3    Olivarez, L.4    Phan, S.H.5
  • 126
    • 4444338573 scopus 로고    scopus 로고
    • Tetrathiomolybdate therapy protects against concanavalin A and carbon tetrachloride hepatic damage in mice
    • Askari FK, Dick RB, Mao M, Brewer GJ. Tetrathiomolybdate therapy protects against concanavalin A and carbon tetrachloride hepatic damage in mice. Exp Biol Med 229:857-863, 2004.
    • (2004) Exp Biol Med , vol.229 , pp. 857-863
    • Askari, F.K.1    Dick, R.B.2    Mao, M.3    Brewer, G.J.4
  • 127
    • 26844452252 scopus 로고    scopus 로고
    • Tetrathiomolybdate protects against cardiac damage by doxorubicin in mice
    • Hou G, Dick R, Abrams GD, Brewer GJ. Tetrathiomolybdate protects against cardiac damage by doxorubicin in mice. J Lab Clin Med 146: 299-303, 2005.
    • (2005) J Lab Clin Med , vol.146 , pp. 299-303
    • Hou, G.1    Dick, R.2    Abrams, G.D.3    Brewer, G.J.4
  • 128
    • 4644266563 scopus 로고    scopus 로고
    • Tetrathiomolybdate protects against liver injury from acetaminophen in mice
    • Ma S, Hou G, Dick RD, Brewer GJ. Tetrathiomolybdate protects against liver injury from acetaminophen in mice. J Appl Res Clin Exp Ther 4:419-426, 2004.
    • (2004) J Appl Res Clin Exp Ther , vol.4 , pp. 419-426
    • Ma, S.1    Hou, G.2    Dick, R.D.3    Brewer, G.J.4
  • 129
    • 33646134391 scopus 로고    scopus 로고
    • The use of tetrathiomolybdate in treating fibrotic, inflammatory, and autoimmune diseases, including the non-obese diabetic mouse model
    • Brewer GJ, Dick R, Zeng C, Hou G. The use of tetrathiomolybdate in treating fibrotic, inflammatory, and autoimmune diseases, including the non-obese diabetic mouse model. J Inorg Biochem 100:927-930, 2006.
    • (2006) J Inorg Biochem , vol.100 , pp. 927-930
    • Brewer, G.J.1    Dick, R.2    Zeng, C.3    Hou, G.4
  • 134
    • 0033981606 scopus 로고    scopus 로고
    • Cardiovascular disease from copper deficiency - a history
    • Klevay LM. Cardiovascular disease from copper deficiency - a history. J Nutr 130:489S-492S, 2000.
    • (2000) J Nutr , vol.130
    • Klevay, L.M.1
  • 135
    • 0015865834 scopus 로고
    • Hypercholesterolemia in rats produced by an increase in the ratio of zinc to copper ingested
    • Klevay LM. Hypercholesterolemia in rats produced by an increase in the ratio of zinc to copper ingested. Am J Clin Nutr 26:1060-1068, 1973.
    • (1973) Am J Clin Nutr , vol.26 , pp. 1060-1068
    • Klevay, L.M.1
  • 136
    • 0028239965 scopus 로고
    • Decreased high density lipoprotein cholesterol and apoprotein A-I in plasma and ultrastructural pathology in cardiac muscle of young pigs fed a diet high in zinc
    • Klevay LM, Pond WG, Medeiros DM. Decreased high density lipoprotein cholesterol and apoprotein A-I in plasma and ultrastructural pathology in cardiac muscle of young pigs fed a diet high in zinc. Nutr Res 14:1227-1239, 1994.
    • (1994) Nutr Res , vol.14 , pp. 1227-1239
    • Klevay, L.M.1    Pond, W.G.2    Medeiros, D.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.