C3′-endo-puckered pyrrolidine containing PNA has favorable geometry for RNA binding: Novel ethano locked PNA (ethano-PNA)

Bioorganic and Medicinal Chemistry

Volumn 21, Issue 14, 2013, Pages 4092-4101

  Banerjee, Anjan ^a   Kumar, Vaijayanti A ^a  

^a NATIONAL CHEMICAL LABORATORY   (India)

Author keywords

Antisense therapeutics; Conformationally constrained PNA; Diagnostics; Peptide nucleic acid (PNA)

Indexed keywords

COMPLEMENTARY DNA; ETHYL [N (N BOC PYRROLIDIN 3 YL 2 AMINOMETHYL) N (N1 THYMINYLACETYL)]GLYCINATE; ETHYL [N (N BOC PYRROLIDIN 3 YL 2 AMINOMETHYL) N (N1 THYMINYLACETYL)]GLYCINE; ETHYL [N (N BOC PYRROLIDIN 3 YL 2 AZIDOMETHYL) N (N1 THYMINYLACETYL)]GLYCINATE; ETHYL [N (N BOC PYRROLIDIN 3 YL 2 FMOC AMINOMETHYL) N (N1 THYMINYLACETYL)]GLYCINE; ETHYL [N (N BOC PYRROLIDIN 3 YL 2 HYDROXYMETHYL) N (N1 THYMINYLACETYL)]GLYCINATE; ETHYL [N (N BOC PYRROLIDIN 3 YL 2 O MESYL METHYL) N (N1 THYMINYLACETYL)]GLYCINATE; ETHYL [N (N BOC PYRROLIDIN 3 YL 2 O TBS METHYL) N (2 CHLOROACETYL)]GLYCINATE; ETHYL [N (N BOC PYRROLIDIN 3 YL 2 O TBS METHYL) N (N1 THYMINYLACETYL)]GLYCINE; ETHYL [N (N BOC PYRROLIDIN 3 YL) 2 O TBS METHYL]GLYCINATE; ETHYL [N (N BOC PYRROLIDIN 3 YL) N (2 CHLOROACETYL)]GLYCINATE; ETHYL [N (N BOC PYRROLIDIN 3 YL) N (N1 THYMINYLACETYL)]GLYCINATE; ETHYL [N (N BOC PYRROLIDIN 3 YL) N (N1 THYMINYLACETYL)]GLYCINE; ETHYL [N BOC PYRROLIDIN 3 YL]GLYCINATE; METHYL (N BOC 4 HYDROXYPYRROLIDINE) 2 CARBOXYLATE; METHYL (N BOC 4 O MESYL PYRROLIDINE) 2 CARBOXYLATE; MONOMER; N BOC 4 AMINO 2 O TBS PROLINOL; N BOC 4 AZIDO 2 O TBS PROLINOL; N BOC 4 AZIDO PROLINOL; N BOC 4 O MESYL PROLINOL; OLIGOMER; PEPTIDE NUCLEIC ACID; PYRROLIDINE DERIVATIVE; RNA; THYMINE; UNCLASSIFIED DRUG; ALCOHOL; PYRROLIDINE;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CONCENTRATION (PARAMETERS); CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DENATURATION; DNA BINDING; DNA DETERMINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NUCLEOTIDE SEQUENCE; PH MEASUREMENT; RNA BINDING; SEQUENCE ANALYSIS; SOLID PHASE SYNTHESIS; STRUCTURE ANALYSIS; TEMPERATURE MEASUREMENT; ULTRAVIOLET RADIATION; CHEMICAL STRUCTURE; CHEMISTRY; CIRCULAR DICHROISM; MASS SPECTROMETRY; METABOLISM;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIRCULAR DICHROISM; ETHANOL; MOLECULAR STRUCTURE; PEPTIDE NUCLEIC ACIDS; PYRROLIDINES; RNA; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 84879028164     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2013.05.015     Document Type: Article

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