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Volumn 54, Issue 7, 2013, Pages 1988-1997

Gene expression in skeletal muscle after an acute intravenous GH bolus in human subjects: Identification of a mechanism regulating ANGPTL4

Author keywords

Angiopoietin related protein like 4; Growth hormone; Human gene array; Lipid metabolism

Indexed keywords

ANGIOPOIETIN; ANGIOPOIETIN RELATED PROTEIN LIKE 4; CYTOKINE INDUCIBLE SH2 CONTAINING PROTEIN; FATTY ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN 1A; INSULIN; JANUS KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE CLASS 2B; PROTEIN SH2; RECOMBINANT GROWTH HORMONE; STAT5 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 1; SUPPRESSOR OF CYTOKINE SIGNALING 2; SUPPRESSOR OF CYTOKINE SIGNALING 3; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 84878997435     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.P034520     Document Type: Article
Times cited : (19)

References (47)
  • 1
    • 65249171425 scopus 로고    scopus 로고
    • Effects of growth hormone on glucose, lipid, and protein metabolism in human subjects
    • Møller, N., and J. O. Jørgensen. 2009. Effects of growth hormone on glucose, lipid, and protein metabolism in human subjects. Endocr. Rev. 30: 152-177.
    • (2009) Endocr. Rev. , vol.30 , pp. 152-177
    • Møller, N.1    Jørgensen, J.O.2
  • 3
    • 0036906508 scopus 로고    scopus 로고
    • Lipoprotein lipase: Genetics, lipid uptake, and regulation
    • DOI 10.1194/jlr.R200015-JLR200
    • Merkel, M., R. H. Eckel, and I. J. Goldberg. 2002. Lipoprotein lipase: genetics, lipid uptake, and regulation. J. Lipid Res. 43: 1997-2006. (Pubitemid 35471065)
    • (2002) Journal of Lipid Research , vol.43 , Issue.12 , pp. 1997-2006
    • Merkel, M.1    Eckel, R.H.2    Goldberg, I.J.3
  • 4
    • 0034235093 scopus 로고    scopus 로고
    • Regulation of lipoprotein lipase and hormone-sensitive lipase activity and gene expression in adipose and muscle tissue by growth hormone treatment during weight loss in obese patients
    • DOI 10.1053/meta.2000.6738
    • Richelsen, B., S. B. Pedersen, K. Kristensen, J. D. Børglum, H. Nørrelund, J. S. Christiansen, and J. O. Jørgensen. 2000. Regulation of lipoprotein lipase and hormone-sensitive lipase activity and gene expression in adipose and muscle tissue by growth hormone treatment during weight loss in obese patients. Metabolism. 49: 906-911. (Pubitemid 30483445)
    • (2000) Metabolism: Clinical and Experimental , vol.49 , Issue.7 , pp. 906-911
    • Richelsen, B.1    Pedersen, S.B.2    Kristensen, K.3    Borglum, J.D.4    Norrelund, H.5    Christiansen, J.S.6    Jorgensen, J.O.L.7
  • 5
    • 0016823460 scopus 로고
    • Serum lipids in acromegaly
    • Nikkila, E. A., and R. Pelkonen. 1975. Serum lipids in acromegaly. Metabolism. 24: 829-838.
    • (1975) Metabolism , vol.24 , pp. 829-838
    • Nikkila, E.A.1    Pelkonen, R.2
  • 7
    • 0035491321 scopus 로고    scopus 로고
    • Pharmacological Antilipolysis Restores Insulin Sensitivity during Growth Hormone Exposure
    • Nielsen, S., N. Møller, J. S. Christiansen, and J. O. Jørgensen. 2001. Pharmacological antilipolysis restores insulin sensitivity during growth hormone exposure. Diabetes. 50: 2301-2308. (Pubitemid 33641915)
    • (2001) Diabetes , vol.50 , Issue.10 , pp. 2301-2308
    • Nielsen, S.1    Moller, N.2    Christiansen, J.S.3    Jorgensen, J.O.L.4
  • 8
    • 26044464801 scopus 로고    scopus 로고
    • Influence of the crosstalk between growth hormone and insulin signalling on the modulation of insulin sensitivity
    • DOI 10.1016/j.ghir.2005.07.001, PII S1096637405000754
    • Dominici, F. P., D. P. Argentino, M. C. Munoz, J. G. Miquet, A. I. Sotelo, and D. Turyn. 2005. Influence of the crosstalk between growth hormone and insulin signalling on the modulation of insulin sensitivity. Growth Horm. IGF Res. 15: 324-336. (Pubitemid 41403767)
    • (2005) Growth Hormone and IGF Research , vol.15 , Issue.5 , pp. 324-336
    • Dominici, F.P.1    Argentino, D.P.2    Munoz, M.C.3    Miquet, J.G.4    Sotelo, A.I.5    Turyn, D.6
  • 9
    • 34249656368 scopus 로고    scopus 로고
    • Growth hormone regulation of p85alpha expression and phosphoinositide 3-kinase activity in adipose tissue: Mechanism for growth hormone-mediated insulin resistance
    • DOI 10.2337/db06-0299
    • del Rincon, J. P., K. Iida, B. D. Gaylinn, C. E. McCurdy, J. W. Leitner, L. A. Barbour, J. J. Kopchick, J. E. Friedman, B. Draznin, and M. O. Thorner. 2007. Growth hormone regulation of p85alpha expression and phosphoinositide 3-kinase activity in adipose tissue: mechanism for growth hormone-mediated insulin resistance. Diabetes. 56: 1638-1646. (Pubitemid 46842597)
    • (2007) Diabetes , vol.56 , Issue.6 , pp. 1638-1646
    • Del, R.J.-P.1    Iida, K.2    Gaylinn, B.D.3    McCurdy, C.E.4    Leitner, J.W.5    Barbour, L.A.6    Kopchick, J.J.7    Friedman, J.E.8    Draznin, B.9    Thorner, M.O.10
  • 11
    • 47549084450 scopus 로고    scopus 로고
    • Growth hormone signaling in vivo in human muscle and adipose tissue: Impact of insulin, substrate background, and growth hormone receptor blockade
    • DOI 10.1210/jc.2007-2414
    • Nielsen, C., L. C. Gormsen, N. Jessen, S. B. Pedersen, N. Møller, S. Lund, and J. O. Jørgensen. 2008. Growth hormone signaling in vivo in human muscle and adipose tissue: impact of insulin, substrate background, and growth hormone receptor blockade. J. Clin. Endocrinol. Metab. 93: 2842-2850. (Pubitemid 352008560)
    • (2008) Journal of Clinical Endocrinology and Metabolism , vol.93 , Issue.7 , pp. 2842-2850
    • Nielsen, C.1    Gormsen, L.C.2    Jessen, N.3    Pedersen, S.B.4    Moller, N.5    Lund, S.6    Jorgensen, J.O.L.7
  • 15
    • 58149352421 scopus 로고    scopus 로고
    • Ghrelin infusion in humans induces acute insulin resistance and lipolysis independent of growth hormone signaling
    • Vestergaard, E. T., L. C. Gormsen, N. Jessen, S. Lund, T. K. Hansen, N. Møller, and J. O. Jørgensen. 2008. Ghrelin infusion in humans induces acute insulin resistance and lipolysis independent of growth hormone signaling. Diabetes. 57: 3205-3210.
    • (2008) Diabetes , vol.57 , pp. 3205-3210
    • Vestergaard, E.T.1    Gormsen, L.C.2    Jessen, N.3    Lund, S.4    Hansen, T.K.5    Møller, N.6    Jørgensen, J.O.7
  • 16
    • 77956587382 scopus 로고    scopus 로고
    • Exercise and fasting activate growth hormone-dependent myocellular signal transducer and activator of transcription-5b phosphorylation and insulin-like growth factor-I messenger ribonucleic acid expression in humans
    • Vendelbo, M. H., J. O. Jørgensen, S. B. Pedersen, L. C. Gormsen, S. Lund, O. Schmitz, N. Jessen, and N. Møller. 2010. Exercise and fasting activate growth hormone-dependent myocellular signal transducer and activator of transcription-5b phosphorylation and insulin-like growth factor-I messenger ribonucleic acid expression in humans. J. Clin. Endocrinol. Metab. 95: E64-E68.
    • (2010) J. Clin. Endocrinol. Metab. , vol.95
    • Vendelbo, M.H.1    Jørgensen, J.O.2    Pedersen, S.B.3    Gormsen, L.C.4    Lund, S.5    Schmitz, O.6    Jessen, N.7    Møller, N.8
  • 18
    • 0034864326 scopus 로고    scopus 로고
    • GH regulation of IGF-I and suppressor of cytokine signaling gene expression in C2C12 skeletal muscle cells
    • DOI 10.1210/en.142.9.3890
    • Sadowski, C. L., T. T. Wheeler, L. H. Wang, and H. B. Sadowski. 2001. GH regulation of IGF-I and suppressor of cytokine signaling gene expression in C2C12 skeletal muscle cells. Endocrinology. 142: 3890-3900. (Pubitemid 32802661)
    • (2001) Endocrinology , vol.142 , Issue.9 , pp. 3890-3900
    • Sadowski, C.L.1    Wheeler, T.T.2    Wang, L.-H.3    Sadowski, H.B.4
  • 19
    • 0035827663 scopus 로고    scopus 로고
    • Insulin induction of SOCS-2 and SOCS-3 mRNA expression in C2C12 skeletal muscle cells is mediated by Stat5*
    • Sadowski, C. L., T. S. Choi, M. Le, T. T. Wheeler, L. H. Wang, and H. B. Sadowski. 2001. Insulin induction of SOCS-2 and SOCS-3 mRNA expression in C2C12 skeletal muscle cells is mediated by Stat5*. J. Biol. Chem. 276: 20703-20710.
    • (2001) J. Biol. Chem. , vol.276 , pp. 20703-20710
    • Sadowski, C.L.1    Choi, T.S.2    Le, M.3    Wheeler, T.T.4    Wang, L.H.5    Sadowski, H.B.6
  • 21
    • 0034967001 scopus 로고    scopus 로고
    • Microarray analysis of the in vivo effects of hypophysectomy and growth hormone treatment on gene expression in the rat
    • DOI 10.1210/en.142.7.3163
    • Flores-Morales, A., N. Stahlberg, P. Tollet-Egnell, J. Lundeberg, R. L. Malek, J. Quackenbush, N. H. Lee, and G. Norstedt. 2001. Microarray analysis of the in vivo effects of hypophysectomy and growth hormone treatment on gene expression in the rat. Endocrinology. 142: 3163-3176. (Pubitemid 32577105)
    • (2001) Endocrinology , vol.142 , Issue.7 , pp. 3163-3176
    • Flores-Morales, A.1    Stahlberg, N.2    Tollet-Egnell, P.3    Lundeberg, J.4    Malek, R.L.5    Quackenbush, J.6    Lee, N.H.7    Norstedt, G.8
  • 23
    • 0346457118 scopus 로고    scopus 로고
    • Oligomerization and Regulated Proteolytic Processing of Angiopoietin-like Protein 4
    • DOI 10.1074/jbc.M307583200
    • Ge, H., G. Yang, L. Huang, D. L. Motola, T. Pourbahrami, and C. Li. 2004. Oligomerization and regulated proteolytic processing of angiopoietin-like protein 4. J. Biol. Chem. 279: 2038-2045. (Pubitemid 38084475)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.3 , pp. 2038-2045
    • Ge, H.1    Yang, G.2    Huang, L.3    Motola, D.L.4    Pourbahrami, T.5    Li, C.6
  • 25
    • 76549112457 scopus 로고    scopus 로고
    • Modulation of plasma TG lipolysis by Angiopoietin-like proteins and GPIHBP1
    • Lichtenstein, L., and S. Kersten. 2010. Modulation of plasma TG lipolysis by Angiopoietin-like proteins and GPIHBP1. Biochim. Biophys. Acta. 1801: 415-420.
    • (2010) Biochim. Biophys. Acta , vol.1801 , pp. 415-420
    • Lichtenstein, L.1    Kersten, S.2
  • 26
    • 79957895547 scopus 로고    scopus 로고
    • Angptl4 deficiency decreases serum triglyceride levels in lowdensity lipoprotein receptor knockout mice and streptozotocininduced diabetic mice
    • Adachi, H., T. Kondo, G. Y. Koh, A. Nagy, Y. Oike, and E. Araki. 2011. Angptl4 deficiency decreases serum triglyceride levels in lowdensity lipoprotein receptor knockout mice and streptozotocininduced diabetic mice. Biochem. Biophys. Res. Commun. 409: 177-180.
    • (2011) Biochem. Biophys. Res. Commun. , vol.409 , pp. 177-180
    • Adachi, H.1    Kondo, T.2    Koh, G.Y.3    Nagy, A.4    Oike, Y.5    Araki, E.6
  • 27
    • 34047177395 scopus 로고    scopus 로고
    • Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL
    • DOI 10.1038/ng1984, PII NG1984
    • Romeo, S., L. A. Pennacchio, Y. Fu, E. Boerwinkle, A. Tybjaerg-Hansen, H. H. Hobbs, and J. C. Cohen. 2007. Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL. Nat. Genet. 39: 513-516. (Pubitemid 46514768)
    • (2007) Nature Genetics , vol.39 , Issue.4 , pp. 513-516
    • Romeo, S.1    Pennacchio, L.A.2    Fu, Y.3    Boerwinkle, E.4    Tybjaerg-Hansen, A.5    Hobbs, H.H.6    Cohen, J.C.7
  • 28
    • 71949101616 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) but not PPARalpha serves as a plasma free fatty acid sensor in liver
    • Sanderson, L. M., T. Degenhardt, A. Koppen, E. Kalkhoven, B. Desvergne, M. Muller, and S. Kersten. 2009. Peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) but not PPARalpha serves as a plasma free fatty acid sensor in liver. Mol. Cell. Biol. 29: 6257-6267.
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 6257-6267
    • Sanderson, L.M.1    Degenhardt, T.2    Koppen, A.3    Kalkhoven, E.4    Desvergne, B.5    Muller, M.6    Kersten, S.7
  • 29
    • 0343060983 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma target gene encoding a novel angiopoietin-related protein associated with adipose differentiation
    • DOI 10.1128/MCB.20.14.5343-5349.2000
    • Yoon, J. C., T. W. Chickering, E. D. Rosen, B. Dussault, Y. Qin, A. Soukas, J. M. Friedman, W. E. Holmes, and B. M. Spiegelman. 2000. Peroxisome proliferator-activated receptor gamma target gene encoding a novel angiopoietin-related protein associated with adipose differentiation. Mol. Cell. Biol. 20: 5343-5349. (Pubitemid 30431587)
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.14 , pp. 5343-5349
    • Cliff, Y.J.1    Chickering, T.W.2    Rosen, E.D.3    Dussault, B.4    Qin, Y.5    Soukas, A.6    Friedman, J.M.7    Holmes, W.E.8    Spiegelman, B.M.9
  • 30
    • 0034666157 scopus 로고    scopus 로고
    • Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target gene
    • Kersten, S., S. Mandard, N. S. Tan, P. Escher, D. Metzger, P. Chambon, F. J. Gonzalez, B. Desvergne, and W. Wahli. 2000. Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target gene. J. Biol. Chem. 275: 28488-28493.
    • (2000) J. Biol. Chem. , vol.275 , pp. 28488-28493
    • Kersten, S.1    Mandard, S.2    Tan, N.S.3    Escher, P.4    Metzger, D.5    Chambon, P.6    Gonzalez, F.J.7    Desvergne, B.8    Wahli, W.9
  • 32
    • 62749136195 scopus 로고    scopus 로고
    • Muscle-derived angiopoietin-like protein 4 is induced by fatty acids via peroxisome proliferator-activated receptor (PPAR)-delta and is of metabolic relevance in humans
    • Staiger, H., C. Haas, J. Machann, R. Werner, M. Weisser, F. Schick, F. Machicao, N. Stefan, A. Fritsche, and H. U. Haring. 2009. Muscle-derived angiopoietin-like protein 4 is induced by fatty acids via peroxisome proliferator-activated receptor (PPAR)-delta and is of metabolic relevance in humans. Diabetes. 58: 579-589.
    • (2009) Diabetes , vol.58 , pp. 579-589
    • Staiger, H.1    Haas, C.2    Machann, J.3    Werner, R.4    Weisser, M.5    Schick, F.6    Machicao, F.7    Stefan, N.8    Fritsche, A.9    Haring, H.U.10
  • 34
    • 34447511610 scopus 로고    scopus 로고
    • Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: Potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation
    • DOI 10.1074/jbc.M611214200
    • Crunkhorn, S., F. Dearie, C. Mantzoros, H. Gami, W. S. da Silva, D. Espinoza, R. Faucette, K. Barry, A. C. Bianco, and M. E. Patti. 2007. Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation. J. Biol. Chem. 282: 15439-15450. (Pubitemid 47093279)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.21 , pp. 15439-15450
    • Crunkhorn, S.1    Dearie, F.2    Mantzoros, C.3    Gami, H.4    Da, S.W.S.5    Espinoza, D.6    Faucette, R.7    Barry, K.8    Bianco, A.C.9    Patti, M.E.10
  • 37
    • 33847684669 scopus 로고    scopus 로고
    • Growth hormone stimulates adipogenesis of 3T3-L1 cells through activation of the Stat5A/5B-PPARgamma pathway
    • DOI 10.1677/jme.1.02154
    • Kawai, M., N. Namba, S. Mushiake, Y. Etani, R. Nishimura, M. Makishima, and K. Ozono. 2007. Growth hormone stimulates adipogenesis of 3T3-L1 cells through activation of the Stat5A/5BPPARgamma pathway. J. Mol. Endocrinol. 38: 19-34. (Pubitemid 46351590)
    • (2007) Journal of Molecular Endocrinology , vol.38 , Issue.1-2 , pp. 19-34
    • Kawai, M.1    Namba, N.2    Mushiake, S.3    Etani, Y.4    Nishimura, R.5    Makishima, M.6    Ozono, K.7
  • 39
    • 0034657348 scopus 로고    scopus 로고
    • The role of STAT proteins in growth hormone signaling
    • Herrington, J., L. S. Smit, J. Schwartz, and C. Carter-Su. 2000. The role of STAT proteins in growth hormone signaling. Oncogene. 19: 2585-2597. (Pubitemid 30339214)
    • (2000) Oncogene , vol.19 , Issue.21 , pp. 2585-2597
    • Herrington, J.1    Smit, L.S.2    Schwartz, J.3    Carter-Su, C.4
  • 42
    • 0033544899 scopus 로고    scopus 로고
    • SOCS/CIS protein inhibition of growth hormone-stimulated STAT5 signaling by multiple mechanisms
    • Ram, P. A., and D. J. Waxman. 1999. SOCS/CIS protein inhibition of growth hormone-stimulated STAT5 signaling by multiple mechanisms. J. Biol. Chem. 274: 35553-35561. (Pubitemid 129512851)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.50 , pp. 35553-35561
    • Ram, P.A.1    Waxman, D.J.2
  • 44
    • 77957356185 scopus 로고    scopus 로고
    • Defining the epigenetic actions of growth hormone: Acute chromatin changes accompany GHactivated gene transcription
    • Chia, D. J., and P. Rotwein. 2010. Defining the epigenetic actions of growth hormone: acute chromatin changes accompany GHactivated gene transcription. Mol. Endocrinol. 24: 2038-2049.
    • (2010) Mol. Endocrinol. , vol.24 , pp. 2038-2049
    • Chia, D.J.1    Rotwein, P.2
  • 45
    • 84860206692 scopus 로고    scopus 로고
    • Regulation and cellular functions of class II phosphoinositide 3-kinases
    • Falasca, M., and T. Maffucci. 2012. Regulation and cellular functions of class II phosphoinositide 3-kinases. Biochem. J. 443: 587-601.
    • (2012) Biochem. J. , vol.443 , pp. 587-601
    • Falasca, M.1    Maffucci, T.2
  • 46
    • 79960089146 scopus 로고    scopus 로고
    • Identification of novel GH-regulated pathway of lipid metabolism in adipose tissue: A gene expression study in hypopituitary men
    • Zhao, J. T., M. J. Cowley, P. Lee, V. Birzniece, W. Kaplan, and K. K. Ho. 2011. Identification of novel GH-regulated pathway of lipid metabolism in adipose tissue: a gene expression study in hypopituitary men. J. Clin. Endocrinol. Metab. 96: E1188-E1196.
    • (2011) J. Clin. Endocrinol. Metab. , vol.96
    • Zhao, J.T.1    Cowley, M.J.2    Lee, P.3    Birzniece, V.4    Kaplan, W.5    Ho, K.K.6
  • 47
    • 21344434775 scopus 로고    scopus 로고
    • Diverging regulation of pyruvate dehydrogenase kinase isoform gene expression in cultured human muscle cells
    • DOI 10.1111/j.1742-4658.2005.04713.x
    • Abbot, E. L., J. G. McCormack, C. Reynet, D. G. Hassall, K. W. Buchan, and S. J. Yeaman. 2005. Diverging regulation of pyruvate dehydrogenase kinase isoform gene expression in cultured human muscle cells. FEBS J. 272: 3004-3014. (Pubitemid 40904688)
    • (2005) FEBS Journal , vol.272 , Issue.12 , pp. 3004-3014
    • Abbot, E.L.1    McCormack, J.G.2    Reynet, C.3    Hassall, D.G.4    Buchan, K.W.5    Yeaman, S.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.