GH regulation of IGF-I and suppressor of cytokine signaling gene expression in C2C12 skeletal muscle cells

Endocrinology

Volumn 142, Issue 9, 2001, Pages 3890-3900

  Sadowski, Cynthia L ^a   Wheeler, Thomas T ^b   Wang, Lu Hai ^a   Sadowski, Henry B ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b RUAKURA RESEARCH CENTRE   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GROWTH HORMONE; GROWTH HORMONE RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN; PROTEIN KINASE B; SOMATOMEDIN C; STAT5 PROTEIN;

ANIMAL CELL; ARTICLE; CELL LINE; ENZYME ACTIVATION; GENE ACTIVATION; GENE CONTROL; GENE EXPRESSION; HORMONAL REGULATION; MUSCLE CELL; MYOBLAST; MYOTUBE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SKELETAL MUSCLE;

EID: 0034864326     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.142.9.8365     Document Type: Article

References (54)

1. Mode of action of pituitary growth hormone on target cells
2. Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase
3. Molecular mechanism of growth hormone action
4. Signaling via JAK tyrosine kinases: Growth hormone receptor as a model system
5. Growth-hormone-receptor and cytokine-receptor-family signaling
6. The role of STAT proteins in growth hormone signaling
7. STATs and gene regulation
8. Effect of growth hormone on carbohydrate and lipid metabolism
9. Growth hormone and prolactin stimulate tyrosine phosphorylation of insulin receptor substrate-1, -2, and -3, their association with p85 phosphatidylinositol 3-kinase (PI3-kinase), and concomitantly PI3-kinase activation via JAK2 kinase
10. Growth hormone stimulates the tyrosine kinase activity of JAK2 and induces tyrosine phosphorylation of insulin receptor substrates and Shc in rat tissues
11. Growth hormone, interferon-γ, and leukemia inhibitory factor promoted tyrosyl phosphorylation of insulin receptor substrate-1
12. Growth hormone, interferon-γ, and leukemia inhibitory factor utilize insulin receptor substrate-2 in intracellular signaling
13. Growth hormone-produced tyrosyl phosphorylation of SHC proteins and SHC association with Grb2
14. Requirement for phosphoinositide 3-OH kinase in growth hormone signalling to the mitogen-activated protein kinase and p70s6k pathways
15. Somatomedin: Proposed designation for sulphation factor
16. Growth hormone rapidly activates insulin-like growth factor I gene transcription in vivo
17. Mice carrying null mutations of the genes encoding insulin-like growth factor I (fgf-1) and type I IGF receptor (Igf1r)
18. Role of insulin-like growth factors in embryonic and postnatal growth
19. IGF-I is required for normal embryonic growth in mice
20. A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse)
21. Regulation of rat growth hormone receptor gene expression
22. Growth hormone stimulates longitudinal bone growth directly
23. Mechanism of the stimulatory effect of growth hormone on longitudinal bone growth
24. Normal growth and development in the absence of hepatic insulin-like growth factor I
25. Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice
26. Growth hormone regulates the level of insulin-like growth factor-I mRNA in rat skeletal muscle
27. Expression and regulation of insulin-like growth factor-I (IGF-I) and IGF-binding protein messenger ribonucleic acid levels in tissues of hypophysectomized rats infused with IGF-I and growth hormone
28. Growth hormone stimulates tyrosine phosphorylation of JAK2 and Stat5, but not insulin receptor substrate-1 or SHC proteins in liver and skeletal muscle of normal rats in vivo
29. Growth hormone-mediated regulation of insulin-like growth factor I promoter activity in C6 glioma cells
30. A family of cytokine-inducible inhibitors of signalling
31. Interaction of human suppressor of cytokine signaling (SOCS)-2 with the insulin-like growth factor-I receptor
32. Gigantism in mice lacking suppressor of cytokine signalling-2
33. Stat5 phosphorylation status and DNA-binding activity in the bovine and murine mammary glands
34. A common nuclear signal transduction pathway activated by growth factor and cytokine receptors
35. The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter
36. Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs
37. A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain
38. Developmental regulation of insulin-like growth factor-I and growth hormone receptor gene expression
39. Sex differences in the ultradian pattern of plasma growth hormone concentrations in mice
40. Growth hormone preferentially induces the rapid, transient expression of SOCS-3, a novel inhibitor of cytokine receptor signaling
41. Stat5b mediates the GH-induced expression of SOCS-2 and SOCS-3 mRNA in the liver
42. SOCS/CIS protein inhibition of growth hormone-stimulated STAT5 signaling by multiple mechanisms
43. Growth hormone regulation of SOCS-2, SOCS-3, and CIS messenger ribonucleic acid expression in the rat
44. Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses
45. Insulin-like growth factor I: Molecular biology and relevance to tissue-specific expression and action
46. Molecular regulation of insulin-like growth factor-I and its principal binding protein, IGFBP-3
47. Growth hormone and the insulin-like growth factor system in myogenesis
48. Sex change in cytochrome P-450 phenotype by growth hormone treatment of adult rat hepatocytes maintained in a culture system on matrigel
49. Matrigel treatment of primary hepatocytes following DNA transfection enhances responsiveness to extracellular stimuli
50. Stat5 as a target for regulation by extracellular matrix
51. Regulation of mammary differentiation by extracellular matrix involves protein-tyrosine phosphatases
52. Negative regulation of cytokine signaling: STAT-induced STAT inhibitor
53. +2-dependent calcineurin signalling pathway