Ablation of dihydroceramide desaturase 1, a therapeutic target for the treatment of metabolic diseases, simultaneously stimulates anabolic and catabolic signaling

Molecular and Cellular Biology

Volumn 33, Issue 11, 2013, Pages 2353-2369

  Siddique, Monowarul M ^a   Li, Ying ^a   Wang, Liping ^b   Ching, Jianhong ^a   Mal, Mainak ^a   Ilkayeva, Olga ^b   Wu, Ya Jun ^c   Bay, Boon Huat ^c   Summers, Scott A ^a,b  

^a DUKE NUS MEDICAL SCHOOL   (Singapore)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROCERAMIDE DESATURASE 1; ENZYME; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CATABOLISM; CONTROLLED STUDY; ELECTRON TRANSPORT; EMBRYO; ENZYME ACTIVATION; METABOLIC DISORDER; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ADENOSINE TRIPHOSPHATE; AMINO ACIDS; ANIMALS; APOPTOSIS; AUTOPHAGY; CELL PROLIFERATION; CERAMIDES; FIBROBLASTS; MEMBRANE PROTEINS; MICE; MICE, MUTANT STRAINS; MITOCHONDRIA; OXIDOREDUCTASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; SPHINGOLIPIDS;

EID: 84878993976     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00226-13     Document Type: Article

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