Ablation of Dihydroceramide Desaturase Confers Resistance to Etoposide-Induced Apoptosis In Vitro

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Siddique, Monowarul M ^a   Bikman, Benjamin T ^a,b   Wang, Liping ^c   Ying, Li ^a   Reinhardt, Erin ^a   Shui, Guanghou ^d   Wenk, Markus R ^d   Summers, Scott A ^a,c  

^a DUKE NUS MEDICAL SCHOOL   (Singapore)

^b BRIGHAM YOUNG UNIVERSITY   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

CERAMIDE; DIHYDROCERAMIDE DESATURASE 1; MITOGEN ACTIVATED PROTEIN KINASE; SPHINGOLIPID; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL PROTECTION; CELL SURVIVAL; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; IN VITRO STUDY; LIPIDOMICS; MOUSE; NONHUMAN; PROTEIN DEPLETION; SIGNAL TRANSDUCTION; WILD TYPE;

ANIMALS; APOPTOSIS; CELL SURVIVAL; CERAMIDES; CYTOPROTECTION; DOWN-REGULATION; EMBRYO, MAMMALIAN; ENZYME ACTIVATION; ETOPOSIDE; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLASTS; GENE DELETION; MAP KINASE SIGNALING SYSTEM; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, INBRED C57BL; MODELS, BIOLOGICAL; OXIDOREDUCTASES; PROTEIN PHOSPHATASE 2; PROTO-ONCOGENE PROTEINS C-AKT; SPHINGOLIPIDS;

EID: 84866270544     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0044042     Document Type: Article

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