Curcumin Acts as a Pro-Oxidant Inducing Apoptosis Via JNKs in the Isolated Perfused Rana ridibunda Heart

Journal of Experimental Zoology Part A: Ecological Genetics and Physiology

Volumn 319, Issue 6, 2013, Pages 328-339

  Aggeli, Ioanna Katerina ^a   Koustas, Evaggelos ^a   Gaitanaki, Catherine ^a   Beis, Isidoros ^a  

^a UNIVERSITY OF ATHENS   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; CURCUMIN; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL; APOPTOSIS; ARTICLE; DRUG EFFECT; HEART; METABOLISM; ORGAN CULTURE TECHNIQUE; OXIDATION REDUCTION REACTION; PELOPHYLAX RIDIBUNDUS; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CURCUMIN; HEART; JNK MITOGEN-ACTIVATED PROTEIN KINASES; ORGAN CULTURE TECHNIQUES; OXIDATION-REDUCTION; PHOSPHORYLATION; RANA RIDIBUNDA; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

AMPHIBIA; MAMMALIA; RANA RIDIBUNDA;

EID: 84878993616     PISSN: 19325223     EISSN: 19325231     Source Type: Journal    
DOI: 10.1002/jez.1797     Document Type: Article

References (60)

1. Aggeli IK, Gaitanaki C, Lazou A, Beis I. 2001. Activation of multiple MAPK pathways (ERKs, JNKs, p38-MAPK) by diverse stimuli in the amphibian heart. Mol Cell Bioch 221:63-69.
2. Ali MS, Mudagal MP, Goli D. 2009. Cardioprotective effect of tetrahydrocurcumin and rutin on lipid peroxides and antioxidants in experimentally induced myocardial infarction in rats. Pharmazie 64:132-136.
3. Anand P, Thomas SG, Kunnumakkara AB, et al. 2008. Biological activities of curcumin and its analogues (Congeners) made by man and mother nature. Biochem Pharmacol 76:1590-1611.
4. Barzegar A, Moosavi-Movahedi AA. 2011. Intracellular ROS protection efficiency and free radical-scavenging activity of curcumin. PLoS ONE 6:e26012.
5. Bogoyevitch MA. 2000. Signalling via stress-activated mitogen-activated protein kinases in the cardiovascular system. Cardiovasc Res 45:826-842.
6. +. FEBS J 272:4576-4589.
7. Cain CC, Murphy RF. 1988. A chloroquine-resistant Swiss 3T3 cell line with a defect in late endocytic acidification. J Cell Biol 106:269-277.
8. Chen YR, Meyer CF, Tan TH. 1996. Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in gamma radiation-induced apoptosis. J Biol Chem 271:631-634.
9. Chen Q, Wang Y, Xu K, et al. 2010. Curcumin induces apoptosis in human lung adenocarcinoma A549 cells through a reactive oxygen species-dependent mitochondrial signaling pathway. Oncol Rep 23:397-403.
10. Concannon CG, Gorman AM, Samall A. 2003. On the role of Hsp27 in regulating apoptosis. Apoptosis 8:61-70.
11. Cuvillier O, Pirianov G, Kleuser B, et al. 1996. Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate. Nature 381:800-803.
12. Duan W, Yang Y, Yan J, et al. 2012. The effects of curcumin post-treatment against myocardial ischemia and reperfusion by activation of the JAK2/STAT3 signaling pathway. Basic Res Cardiol 107:263-274.
13. 2, semiquinones, and quinones. Free Radic Biol Med 51:2319-2327.
14. Fiorillo C, Becatti M, Pensalfini A, et al. 2008. Curcumin protects cardiac cells against ischemia-reperfusion injury: effects on oxidative stress, NF-kappaB, and JNK pathways. Free Radic Biol Med 45:839-846.
15. França MB, Panek AD, Eleutherio EC. 2007. Oxidative stress and its effects during dehydration. Comp Biochem Physiol A Mol Integr Physiol 146:621-631.
16. Fridovich I. 1999. Fundamental aspects of reactive oxygen species, or what's the matter with oxygen? Ann N Y Acad Sci 893:13-18.
17. Fumarola C, Guidotti GG. 2004. Stress-induced apoptosis: toward a symmetry with receptor-mediated cell death. Apoptosis 9:77-82.
18. Gaitanaki C, Stathopoulou K, Stavridou C, Beis I. 2003. Oxidative stress stimulates multiple MAPK signalling pathways and phosphorylation of the small HSP27 in the perfused amphibian heart. J Exp Biol 206:2759-2769.
19. Gaitanaki C, Papatriantafyllou M, Stathopoulou K, Beis I. 2006. Effects of various oxidants and antioxidants on the p38-MAPK signalling pathway in the perfused amphibian heart. Mol Cell Bioch 291:107-117.
20. 2 induces protective events via the p38-MAPK signalling pathway and ANP in the perfused amphibian heart. J Exp Biol 210:2267-2277.
21. Gaitanaki C, Mastri M, Aggeli IK, Beis I. 2008. Differential roles of p38-MAPK and JNKs in mediating early protection or apoptosis in the hyperthermic perfused amphibian heart. J Exp Biol 211:2524-2532.
22. Giordano FJ. 2005. Oxygen, oxidative stress, hypoxia, and heart failure. J Clin Invest 115:500-508.
23. Griendling KK, Sorescu D, Ushio-Fukai M. 2000. NAD(P)H oxidase: role in cardiovascular biology and disease. Circ Res 86:494-501.
24. Guay J, Lambert H, Gingras-Breton G, Lavoie JN, Huot J, Landry J. 1997. Regulation of actin filament dynamics by p38 map kinase-mediated phosphorylation of heat shock protein 27. J Cell Sci 110:357-368.
25. Han X, Xu B, Beevers CS, et al. 2012. Curcumin inhibits protein phosphatases 2A and 5, leading to activation of mitogen-activated protein kinases and death in tumor cells. Carcinogenesis 33:868-875.
26. Hilchie AL, Furlong SJ, Sutton K, et al. 2010. Curcumin-induced apoptosis in PC3 prostate carcinoma cells is caspase-independent and involves cellular ceramide accumulation and damage to mitochondria. Nutr Cancer 62:379-389.
27. Hua WF, Fu YS, Liao YJ, et al. 2010. Curcumin induces down-regulation of EZH2 expression through the MAPK pathway in MDA-MB-435 human breast cancer cells. Eur J Pharmacol 637:16-21.
28. Huot J, Houle F, Spitz DR, Laundry J. 1996. HSP27 phosphorylation-mediated resistance against actin fragmentation and cell death induced by oxidative stress. Cancer Res 56:273-279.
29. Karmakar S, Banik NL, Patel SJ, Ray SK. 2006. Curcumin activated both receptor-mediated and mitochondria-mediated proteolytic pathways for apoptosis in human glioblastoma T98G cells. Neurosci Lett 407:53-58.
30. Kelly MR, Xu J, Alexander KE, Loo G. 2001. Disparate effects of similar phenolic phytochemicals as inhibitors of oxidative damage to cellular DNA. Mutat Res 485:309-318.
31. Khan S, Heikkila JJ. 2011. Curcumin-induced inhibition of proteasomal activity, enhanced HSP accumulation and the acquisition of thermotolerance in Xenopus laevis A6 cells. Comp Biochem Physiol A Mol Integr Physiol 158:566-576.
32. Kim JH, Park JM, Kim EK, et al. 2010. Curcumin stimulates glucose uptake through AMPK-p38 MAPK pathways in L6 myotube cells. J Cell Physiol 223:771-778.
33. Kourie JI. 1998. Interaction of reactive oxygen species with ion transport mechanisms. Am J Physiol 275:C1-C24.
34. Kyriakis JM, Avruch J. 2001. Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol Rev 81:807-869.
35. Lavoie JN, Lambert H, Hickey E, Weber LA, Landry J. 1995. Modulation of cellular thermoresistance and actin filament stability accompanies phosphorylation-induced changes in the oligomeric structure of heat shock protein 27. Mol Cell Biol 15:505-516.
36. Lee YJ, Kim NY, Suh YA, Lee C. 2011. Involvement of ROS in Curcumin-induced Autophagic Cell Death. Korean J Physiol Pharmacol 15:1-7.
37. Ligeret H, Barthelemy S, Zini R, Tillement JP, Labidalle S, Morin D. 2004. Effects of curcumin and curcumin derivatives on mitochondrial permeability transition pore. Free Radic Biol Med 36:919-929.
38. Liu C, Hong J, Yang H, et al. 2010. Frog skins keep redox homeostasis by antioxidant peptides with rapid radical scavenging ability. Free Radic Biol Med 48:1173-1181.
39. Manikandan R, Thiagarajan R, Beulaja S, Sudhandiran G, Arumugam M. 2010. Curcumin prevents free radical-mediated cataractogenesis through modulations in lens calcium. Free Radic Biol Med 48:483-492.
40. Morsy MA, Abdalla AM, Mahmoud AM, Abdelwahab SA, Mahmoud ME. 2011. Protective effects of curcumin, α-lipoic acid, and N-acetylcysteine against carbon tetrachloride-induced liver fibrosis in rats. J Physiol Biochem 68:29-35.
41. Pearson G, Robinson F, Beers Gibson T, et al. 2001. Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. Endocrine Rev 22:153-183.
42. Pedersen SF, O'Donnell ME, Anderson SE, Cala PM. 2006. Physiology and pathophysiology of Na_/H_exchange and Na_-K_-2Cl_cotransport in the heart, brain, and blood. Am J Physiol Regul Integr Comp Physiol 291:R1-R25.
43. Pinder AW, Burggren WW. 1986. Ventilation and partitioning of oxygen uptake in the frog Rana pipiens: effects of hypoxia and activity. J Exp Biol 126:453-468.
44. Ravindran J, Prasad S, Aggarwal BB. 2009. Curcumin and cancer cells: how many ways can curry kill tumor cells selectively? AAPS J 11:495-510.
45. Rouse J, Cohen P, Trigon S, et al. 1994. A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins. Cell 78:1027-1037.
46. Sánchez Y, Simón GP, Calviño E, de Blas E, Aller P. 2010. Curcumin stimulates reactive oxygen species production and potentiates apoptosis induction by the antitumor drugs arsenic trioxide and lonidamine in human myeloid leukemia cell lines. J Pharmacol Exp Ther 335:114-123.
47. Scharstuhl A, Mutsaers HA, Pennings SW, Russel FG, Wagener FA. 2009. Involvement of VDAC, Bax and ceramides in the efflux of AIF from mitochondria during curcumin-induced apoptosis. PLoS ONE 4:e6688.
48. Schraufstatter E, Bernt H. 1949. Antibacterial action of curcumin and related compounds. Nature 164:456-457.
49. Sharma OP. 1976. Antioxidant activity of curcumin and related compounds. Biochem Pharmacol 25:1811-1812.
50. Singh N, Shrivastav A, Sharma RK. 2009. Curcumin induces caspase and calpain-dependent apoptosis in HT29 human colon cancer cells. Mol Med Report 2:627-631.
51. Srimal RC, Dhawan BN. 1973. Pharmacology of diferuloyl methane (curcumin), a nonsteroidal anti-inflammatory agent. J Pharm Pharmacol 25:447-452.
52. Stathopoulou K, Gaitanaki C, Beis I. 2006. Extracellular pH changes activate the p38-MAPK signalling pathway in the amphibian heart. J Exp Biol 209:1344-1354.
53. Stokoe D, Engel K, Campbell DG, Cohen P, Gaestel M. 1992. Identification of MAPKAP kinase 2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins. FEBS Lett 313:307-313.
54. Strasser A, O'Connor L, Dixit VM. 2000. Apoptosis signaling. Annu Rev Biochem 69:217-245.
55. Teiten MH, Reuter S, Schmucker S, Dicato M, Diederich M. 2009. Induction of heat shock response by curcumin in human leukemia cells. Cancer Lett 279:145-154.
56. Thannickal VJ, Fanburg BL. 2000. Reactive oxygen species in cell signaling. Am J Physiol Lung Cell Mol Physiol 279:L1005-L1028.
57. Weir NM, Selvendiran K, Kutala VK, et al. 2007. Curcumin induces G2/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by modulating Akt and p38 MAPK. Cancer Biol Ther 6:178-184.
58. Yeh CH, Chen TP, Wu YC, Lin YM, Jing Lin P. 2005. Inhibition of NFkappaB activation with curcumin attenuates plasma inflammatory cytokines surge and cardiomyocytic apoptosis following cardiac ischemia/reperfusion. J Surg Res 125:109-116.
59. Yucel AF, Kanter M, Pergel A, Erboga M, Guzel A. 2011. The role of curcumin on intestinal oxidative stress, cell proliferation and apoptosis after ischemia/reperfusion injury in rats. J Mol Histol 42:579-587.
60. Zanke BW, Boudreau K, Rubie E, et al. 1996. The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat. Curr Biol 6:606-613.