Resistance Mutations outside the Integrase Coding Region Have an Effect on Human Immunodeficiency Virus Replicative Fitness but Do Not Affect Its Susceptibility to Integrase Strand Transfer Inhibitors

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Weber, Jan ^a   Rose, Justine D ^b   Vazquez, Ana C ^c   Winner, Dane ^d   Margot, Nicolas ^e   McColl, Damian J ^e   Miller, Michael D ^e   Quiñones Mateu, Miguel E ^b,d  

^a INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

^c KENT STATE UNIVERSITY   (United States)

^d UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

^e GILEAD SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABACAVIR; AMPRENAVIR; DARUNAVIR; DELAVIRDINE; DIDANOSINE; DOLUTEGRAVIR; ELVITEGRAVIR; EMTRICITABINE; GAG PROTEIN; HUMAN IMMUNODEFICIENCY VIRUS PROTEIN; INDINAVIR; INTEGRASE; INTEGRASE INHIBITOR; INTEGRASE STRAND TRANSFER INHIBITOR; LAMIVUDINE; LOPINAVIR; NELFINAVIR; PROTEIN NCP7; PROTEIN P1; PROTEIN P2; PROTEIN P6; PROTEINASE; RALTEGRAVIR; RITONAVIR; RNA DIRECTED DNA POLYMERASE; SAQUINAVIR; STAVUDINE; TENOFOVIR DISOPROXIL; UNCLASSIFIED DRUG; UNINDEXED DRUG; ZIDOVUDINE;

ANTIVIRAL SUSCEPTIBILITY; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG RESISTANCE; DRUG TREATMENT FAILURE; GROUP SPECIFIC ANTIGEN GENE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; NONHUMAN; PHENOTYPE; REPRODUCTIVE FITNESS; SITE DIRECTED MUTAGENESIS; VIRUS CHARACTERIZATION; VIRUS GENE; VIRUS MUTANT; VIRUS MUTATION; VIRUS RECOMBINANT; VIRUS REPLICATION; VIRUS RESISTANCE;

ANTI-RETROVIRAL AGENTS; CELL LINE; HETEROCYCLIC COMPOUNDS, 3-RING; HIV INTEGRASE INHIBITORS; HIV-1; HUMANS; INTEGRASES; MUTATION; PYRROLIDINONES; QUINOLONES;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 84878915307     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0065631     Document Type: Article

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