메뉴 건너뛰기




Volumn 55, Issue 4, 2011, Pages 1403-1413

Human immunodeficiency virus type 1 resistance or cross-resistance to nonnucleoside reverse transcriptase inhibitors currently under development as microbicides

Author keywords

[No Author keywords available]

Indexed keywords

ABACAVIR; AMPRENAVIR; ATAZANAVIR; DAPIVIRINE; DARUNAVIR; DELAVIRDINE; DIDANOSINE; EFAVIRENZ; EMTRICITABINE; ETRAVIRINE; INDINAVIR; LAMIVUDINE; LERSIVIRINE; LOPINAVIR; MICROBICIDE; MIV 160; MIV 170; N [4 CHLORO 3 (3 METHYL 2 BUTENYLOXY)PHENYL] 2 METHYL 3 FURANCARBOTHIOAMIDE; NELFINAVIR; NEVIRAPINE; NONNUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR; RALTEGRAVIR; RECOMBINANT PROTEIN; RITONAVIR; SAQUINAVIR; STAVUDINE; TENOFOVIR; THIOCARBOXANILIDE; TIPRANAVIR; UNCLASSIFIED DRUG; UNINDEXED DRUG; ZIDOVUDINE;

EID: 79953049919     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01426-10     Document Type: Article
Times cited : (27)

References (89)
  • 2
    • 9644291579 scopus 로고    scopus 로고
    • TMC125, a novel next-generation nonnucleoside reverse transcriptase inhibitor active against nonnucleoside reverse transcriptase inhibitor-resistant human immunodeficiency virus type 1
    • Andries, K., et al. 2004. TMC125, a novel next-generation nonnucleoside reverse transcriptase inhibitor active against nonnucleoside reverse transcriptase inhibitor-resistant human immunodeficiency virus type 1. Antimicrob. Agents Chemother. 48:4680-4686.
    • (2004) Antimicrob. Agents Chemother. , vol.48 , pp. 4680-4686
    • Andries, K.1
  • 3
    • 0033863784 scopus 로고    scopus 로고
    • Mutants of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase resistant to nonnucleoside reverse transcriptase inhibitors demonstrate altered rates of RNase H cleavage that correlate with HIV-1 replication fitness in cell culture
    • DOI 10.1128/JVI.74.18.8390-8401.2000
    • Archer, R. H., et al. 2000. Mutants of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase resistant to nonnucleoside reverse transcriptase inhibitors demonstrate altered rates of RNase H cleavage that correlate with HIV-1 replication fitness in cell culture. J. Virol. 74:8390-8401. (Pubitemid 30666690)
    • (2000) Journal of Virology , vol.74 , Issue.18 , pp. 8390-8401
    • Archer, R.H.1    Dykes, C.2    Gerondelis, P.3    Lloyd, A.4    Fay, P.5    Reichman, R.C.6    Bambara, R.A.7    Demeter, L.M.8
  • 4
    • 79953178767 scopus 로고    scopus 로고
    • In vitro selection of novel etravirine-associated resistance mutations in B and non-B HIV-1 subtypes
    • Asahchop, E. L., et al. 2010. In vitro selection of novel etravirine-associated resistance mutations in B and non-B HIV-1 subtypes. Antivir. Ther. 15:A134.
    • (2010) Antivir. Ther. , vol.15
    • Asahchop, E.L.1
  • 5
    • 75749118495 scopus 로고    scopus 로고
    • TMC278, a next-generation nonnucleoside reverse transcriptase inhibitor (NNRTI), active against wild-type and NNRTI-resistant HIV-1
    • Azijn, H., et al. 2010. TMC278, a next-generation nonnucleoside reverse transcriptase inhibitor (NNRTI), active against wild-type and NNRTI-resistant HIV-1. Antimicrob. Agents Chemother. 54:718-727.
    • (2010) Antimicrob. Agents Chemother. , vol.54 , pp. 718-727
    • Azijn, H.1
  • 6
    • 21744462601 scopus 로고    scopus 로고
    • Intravaginal and intrarectal microbicides to prevent HIV infection
    • Balzarini, J., and L. Van Damme. 2005. Intravaginal and intrarectal microbicides to prevent HIV infection. CMAJ 172:461-464.
    • (2005) CMAJ , vol.172 , pp. 461-464
    • Balzarini, J.1    Van Damme, L.2
  • 7
    • 33847390394 scopus 로고    scopus 로고
    • Microbicide drug candidates to prevent HIV infection
    • DOI 10.1016/S0140-6736(07)60202-5, PII S0140673607602025
    • Balzarini, J., and L. Van Damme. 2007. Microbicide drug candidates to prevent HIV infection. Lancet 369:787-797. (Pubitemid 46335821)
    • (2007) Lancet , vol.369 , Issue.9563 , pp. 787-797
    • Balzarini, J.1    Van Damme, L.2
  • 9
  • 10
    • 8244226649 scopus 로고    scopus 로고
    • Highly potent oxathiin carboxanilide derivatives with efficacy against nonnucleoside reverse transcriptase inhibitorresistant human immunodeficiency virus isolates
    • Buckheit, R. W., Jr., et al. 1997. Highly potent oxathiin carboxanilide derivatives with efficacy against nonnucleoside reverse transcriptase inhibitorresistant human immunodeficiency virus isolates. Antimicrob. Agents Chemother. 41:831-837.
    • (1997) Antimicrob. Agents Chemother. , vol.41 , pp. 831-837
    • Buckheit Jr., R.W.1
  • 12
    • 50949097030 scopus 로고    scopus 로고
    • Prevention of SIV rectal transmission and priming of T cell responses in macaques after local pre-exposure application of tenofovir gel
    • Cranage, M., et al. 2008. Prevention of SIV rectal transmission and priming of T cell responses in macaques after local pre-exposure application of tenofovir gel. PLoS Med. 5:e157.
    • (2008) PLoS Med. , vol.5
    • Cranage, M.1
  • 13
    • 53949100884 scopus 로고    scopus 로고
    • Vaginal microbicides and the prevention of HIV transmission
    • Cutler, B., and J. Justman. 2008. Vaginal microbicides and the prevention of HIV transmission. Lancet Infect. Dis. 8:685-697.
    • (2008) Lancet Infect. Dis. , vol.8 , pp. 685-697
    • Cutler, B.1    Justman, J.2
  • 14
    • 32644438459 scopus 로고    scopus 로고
    • Dawn of non-nucleoside inhibitor-based anti-HIV microbicides
    • D'Cruz, O. J., and F. M. Uckun. 2006. Dawn of non-nucleoside inhibitor-based anti-HIV microbicides. J. Antimicrob. Chemother. 57:411-423.
    • (2006) J. Antimicrob. Chemother. , vol.57 , pp. 411-423
    • D'Cruz, O.J.1    Uckun, F.M.2
  • 15
    • 73549115378 scopus 로고    scopus 로고
    • Non-nucleoside reverse transcriptase inhibitors (NNRTIs), their discovery, development, and use in the treatment of HIV-1 infection: A review of the last 20 years (19892009)
    • de Bethune, M.-P. 2009. Non-nucleoside reverse transcriptase inhibitors (NNRTIs), their discovery, development, and use in the treatment of HIV-1 infection: a review of the last 20 years (1989-2009). Antiviral Res. 85:75-90.
    • (2009) Antiviral Res. , vol.85 , pp. 75-90
    • Bethune, M.-P.1
  • 16
    • 12844269825 scopus 로고    scopus 로고
    • Evidence for differences in the sexual transmission efficiency of HIV strains with distinct drug resistance genotypes
    • de Mendoza, C., et al. 2004. Evidence for differences in the sexual transmission efficiency of HIV strains with distinct drug resistance genotypes. Clin. Infect. Dis. 39:1231-1238.
    • (2004) Clin. Infect. Dis. , vol.39 , pp. 1231-1238
    • De Mendoza, C.1
  • 17
    • 0034867418 scopus 로고    scopus 로고
    • Replicative fitness in vivo of HIV-1 variants with multiple drug resistance-associated mutations
    • Devereux, H. L., V. C. Emery, M. A. Johnson, and C. Loveday. 2001. Replicative fitness in vivo of HIV-1 variants with multiple drug resistance-associated mutations. J. Med. Virol. 65:218-224.
    • (2001) J. Med. Virol. , vol.65 , pp. 218-224
    • Devereux, H.L.1    Emery, V.C.2    Johnson, M.A.3    Loveday, C.4
  • 18
    • 39049180393 scopus 로고    scopus 로고
    • Intracellular and plasma efavirenz concentrations in HIV-infected patients switching from successful protease inhibitor-based highly active antiretroviral therapy (HAART) to efavirenz-based HAART (SUSTIPHAR Study)
    • Djabarouti, S., et al. 2006. Intracellular and plasma efavirenz concentrations in HIV-infected patients switching from successful protease inhibitor-based highly active antiretroviral therapy (HAART) to efavirenz-based HAART (SUSTIPHAR Study). J. Antimicrob. Chemother. 58:1090-1093.
    • (2006) J. Antimicrob. Chemother. , vol.58 , pp. 1090-1093
    • Djabarouti, S.1
  • 19
    • 67651015445 scopus 로고    scopus 로고
    • A novel yeast-based recombination method to clone and propagate diverse HIV-1 isolates
    • Dudley, D. M., et al. 2009. A novel yeast-based recombination method to clone and propagate diverse HIV-1 isolates. Biotechniques 46:458-467.
    • (2009) Biotechniques , vol.46 , pp. 458-467
    • Dudley, D.M.1
  • 20
    • 0035811838 scopus 로고    scopus 로고
    • Impact of clinical reverse transcriptase sequences on the replication capacity of HIV-1 drug-resistant mutants
    • DOI 10.1006/viro.2001.0920
    • Dykes, C., et al. 2001. Impact of clinical reverse transcriptase sequences on the replication capacity of HIV-1 drug-resistant mutants. Virology 285:193-203. (Pubitemid 32641881)
    • (2001) Virology , vol.285 , Issue.2 , pp. 193-203
    • Dykes, C.1    Fox, K.2    Lloyd, A.3    Chiulli, M.4    Morse, E.5    Demeter, L.M.6
  • 21
    • 77956225829 scopus 로고    scopus 로고
    • Inhibition of HIV-1 by non-nucleoside reverse transcriptase inhibitors via an induced fit mechanism - Importance of slow dissociation and relaxation rates for antiviral efficacy
    • Elinder, M., et al. 2010. Inhibition of HIV-1 by non-nucleoside reverse transcriptase inhibitors via an induced fit mechanism - importance of slow dissociation and relaxation rates for antiviral efficacy. Biochem. Pharmacol. 80:1133-1140.
    • (2010) Biochem. Pharmacol. , vol.80 , pp. 1133-1140
    • Elinder, M.1
  • 22
    • 33845997440 scopus 로고    scopus 로고
    • Carrageenan/MIV-150 (PC-815), a combination microbicide
    • Fernández-Romero, J. A., et al. 2007. Carrageenan/MIV-150 (PC-815), a combination microbicide. Sex. Transm. Dis. 34:9-14.
    • (2007) Sex. Transm. Dis. , vol.34 , pp. 9-14
    • Fernández-Romero, J.A.1
  • 23
    • 59749098155 scopus 로고    scopus 로고
    • Inhibition of human immunodeficiency virus type 1 infection by the candidate microbicide dapivirine, a nonnucleoside reverse transcriptase inhibitor
    • Fletcher, P., et al. 2009. Inhibition of human immunodeficiency virus type 1 infection by the candidate microbicide dapivirine, a nonnucleoside reverse transcriptase inhibitor. Antimicrob. Agents Chemother. 53:487-495.
    • (2009) Antimicrob. Agents Chemother. , vol.53 , pp. 487-495
    • Fletcher, P.1
  • 24
    • 77951022974 scopus 로고    scopus 로고
    • Development of an in vitro dual-chamber model of the female genital tract as a screening tool for epithelial toxicity
    • Gali, Y., et al. 2010. Development of an in vitro dual-chamber model of the female genital tract as a screening tool for epithelial toxicity. J. Virol. Methods 165:186-197.
    • (2010) J. Virol. Methods , vol.165 , pp. 186-197
    • Gali, Y.1
  • 25
    • 30044431689 scopus 로고    scopus 로고
    • Mutations other than 103N in human immunodeficiency virus type 1 reverse transcriptase (RT) emerge from K103R polymorphism under non-nucleoside RT inhibitor pressure
    • DOI 10.1016/j.virol.2005.09.005, PII S0042682205005660
    • Gatanaga, H., A. Hachiya, S. Kimura, and S. Oka. 2006. Mutations other than 103N in human immunodeficiency virus type 1 reverse transcriptase (RT) emerge from K103R polymorphism under non-nucleoside RT inhibitor pressure. Virology 344:354-362. (Pubitemid 43049623)
    • (2006) Virology , vol.344 , Issue.2 , pp. 354-362
    • Gatanaga, H.1    Hachiya, A.2    Kimura, S.3    Oka, S.4
  • 28
    • 77951213245 scopus 로고    scopus 로고
    • Combinations of mutations in the connection domain of human immunodeficiency virus type 1 reverse transcriptase: Assessing the impact on nucleoside and nonnucleoside reverse transcriptase inhibitor resistance
    • Gupta, S., et al. 2010. Combinations of mutations in the connection domain of human immunodeficiency virus type 1 reverse transcriptase: assessing the impact on nucleoside and nonnucleoside reverse transcriptase inhibitor resistance. Antimicrob. Agents Chemother. 54:1973-1980.
    • (2010) Antimicrob. Agents Chemother. , vol.54 , pp. 1973-1980
    • Gupta, S.1
  • 29
    • 79953671162 scopus 로고    scopus 로고
    • Urea-PETT compounds as a new class of HIV-1 reverse transcriptase inhibitors. 3. Synthesis and further structure-activity relationship studies of PETT analogues
    • Högberg, M., et al. 1999. Urea-PETT compounds as a new class of HIV-1 reverse transcriptase inhibitors. 3. Synthesis and further structure-activity relationship studies of PETT analogues. J. Med. Chem. 43:304.
    • (1999) J. Med. Chem. , vol.43 , pp. 304
    • Högberg, M.1
  • 30
    • 33646173910 scopus 로고    scopus 로고
    • In vitro microbicidal activity of the nonnucleoside reverse transcriptase inhibitor (NNRTI) UC781 against NNRTI-resistant human immunodeficiency virus type 1
    • Hossain, M. M., and M. A. Parniak. 2006. In vitro microbicidal activity of the nonnucleoside reverse transcriptase inhibitor (NNRTI) UC781 against NNRTI-resistant human immunodeficiency virus type 1. J. Virol. 80:4440-4446.
    • (2006) J. Virol. , vol.80 , pp. 4440-4446
    • Hossain, M.M.1    Parniak, M.A.2
  • 31
    • 0036135710 scopus 로고    scopus 로고
    • In vitro analysis of human immunodeficiency virus type 1 resistance to nevirapine and fitness determination of resistant variants
    • Iglesias-Ussel, M. D., C. Casado, E. Yuste, I. Olivares, and C. Lopez-Galindez. 2002. In vitro analysis of human immunodeficiency virus type 1 resistance to nevirapine and fitness determination of resistant variants. J. Gen. Virol. 83:93-101.
    • (2002) J. Gen. Virol. , vol.83 , pp. 93-101
    • Iglesias-Ussel, M.D.1    Casado, C.2    Yuste, E.3    Olivares, I.4    Lopez-Galindez, C.5
  • 32
    • 67650034266 scopus 로고    scopus 로고
    • Virological response to highly active antiretroviral therapy in patients infected with human immunodeficiency virus type 2 (HIV-2) and in patients dually infected with HIV-1 and HIV-2 in the Gambia and emergence of drug-resistant variants
    • Jallow, S., et al. 2009. Virological response to highly active antiretroviral therapy in patients infected with human immunodeficiency virus type 2 (HIV-2) and in patients dually infected with HIV-1 and HIV-2 in the Gambia and emergence of drug-resistant variants. J. Clin. Microbiol. 47:2200-2208.
    • (2009) J. Clin. Microbiol. , vol.47 , pp. 2200-2208
    • Jallow, S.1
  • 33
    • 34248571285 scopus 로고    scopus 로고
    • Development and evaluation of an oligonucleotide ligation assay for detection of drug resistance-associated mutations in the human immunodeficiency virus type 2 pol gene
    • Jallow, S., et al. 2007. Development and evaluation of an oligonucleotide ligation assay for detection of drug resistance-associated mutations in the human immunodeficiency virus type 2 pol gene. J. Clin. Microbiol. 45:1565-1571.
    • (2007) J. Clin. Microbiol. , vol.45 , pp. 1565-1571
    • Jallow, S.1
  • 34
    • 20844451906 scopus 로고    scopus 로고
    • Emergence of drug-resistant HIV-1 after intrapartum administration of single-dose nevirapine is substantially underestimated
    • Johnson, J. A., et al. 2005. Emergence of drug-resistant HIV-1 after intrapartum administration of single-dose nevirapine is substantially underestimated. J. Infect. Dis. 192:16-23.
    • (2005) J. Infect. Dis. , vol.192 , pp. 16-23
    • Johnson, J.A.1
  • 35
    • 77955930318 scopus 로고    scopus 로고
    • Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women
    • Karim, Q. A., et al. 2010. Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women. Science 329:1168-1174.
    • (2010) Science , vol.329 , pp. 1168-1174
    • Karim, Q.A.1
  • 36
    • 58149133691 scopus 로고    scopus 로고
    • Prevalence of nevirapine-associated resistance mutations after single dose prophylactic treatment among antenatal clinic attendees in North Rift Kenya
    • Kiptoo, M., et al. 2008. Prevalence of nevirapine-associated resistance mutations after single dose prophylactic treatment among antenatal clinic attendees in North Rift Kenya. AIDS Res. Hum. Retroviruses 24:1555-1559.
    • (2008) AIDS Res. Hum. Retroviruses , vol.24 , pp. 1555-1559
    • Kiptoo, M.1
  • 37
    • 33747888022 scopus 로고    scopus 로고
    • Relative replication fitness of efavirenz-resistant mutants of HIV-1: Correlation with frequency during clinical therapy and evidence of compensation for the reduced fitness of K103N + L100I by the nucleoside resistance mutation L74V
    • Koval, C. E., C. Dykes, J. Wang, and L. M. Demeter. 2006. Relative replication fitness of efavirenz-resistant mutants of HIV-1: correlation with frequency during clinical therapy and evidence of compensation for the reduced fitness of K103N + L100I by the nucleoside resistance mutation L74V. Virology 353:184-192.
    • (2006) Virology , vol.353 , pp. 184-192
    • Koval, C.E.1    Dykes, C.2    Wang, J.3    Demeter, L.M.4
  • 38
    • 78049262493 scopus 로고    scopus 로고
    • Distinct mutation pathways of non-subtype B HIV-1 during in vitro resistance selection with nonnucleoside reverse transcriptase inhibitors
    • Lai, M.-T., et al. 2010. Distinct mutation pathways of non-subtype B HIV-1 during in vitro resistance selection with nonnucleoside reverse transcriptase inhibitors. Antimicrob. Agents Chemother. 54:4812-4824.
    • (2010) Antimicrob. Agents Chemother. , vol.54 , pp. 4812-4824
    • Lai, M.-T.1
  • 39
    • 33646342770 scopus 로고    scopus 로고
    • Microbicides and other topical strategies to prevent vaginal transmission of HIV
    • Lederman, M. M., R. E. Offord, and O. Hartley. 2006. Microbicides and other topical strategies to prevent vaginal transmission of HIV. Nat. Rev. Immunol. 6:371-382.
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 371-382
    • Lederman, M.M.1    Offord, R.E.2    Hartley, O.3
  • 40
    • 29744461100 scopus 로고    scopus 로고
    • Prioritizing prevention of HIV and sexually transmitted infections: First-generation vaginal microbicides
    • Madan, R. P., M. J. Keller, and B. C. Herold. 2006. Prioritizing prevention of HIV and sexually transmitted infections: first-generation vaginal microbicides. Curr. Opin. Infect. Dis. 19:49-54.
    • (2006) Curr. Opin. Infect. Dis. , vol.19 , pp. 49-54
    • Madan, R.P.1    Keller, M.J.2    Herold, B.C.3
  • 41
    • 75749098448 scopus 로고    scopus 로고
    • Resistance-associated mutations to etravirine (TMC-125) in Antiretroviral-naive patients infected with non-B HIV-1 subtypes
    • Maiga, A. I., et al. 2009. Resistance-associated mutations to etravirine (TMC-125) in Antiretroviral-naive patients infected with non-B HIV-1 subtypes. Antimicrob. Agents Chemother. 54:728-733.
    • (2009) Antimicrob. Agents Chemother. , vol.54 , pp. 728-733
    • Maiga, A.I.1
  • 42
    • 33747137566 scopus 로고    scopus 로고
    • Is HIV drug resistance a limiting factor in the development of anti-HIV NNRTI and NRTI-based vaginal microbicide strategies?
    • Martinez, J., P. Coplan, and M. A. Wainberg. 2006. Is HIV drug resistance a limiting factor in the development of anti-HIV NNRTI and NRTI-based vaginal microbicide strategies? Antiviral Res. 71:343-350.
    • (2006) Antiviral Res. , vol.71 , pp. 343-350
    • Martinez, J.1    Coplan, P.2    Wainberg, M.A.3
  • 43
    • 22344443325 scopus 로고    scopus 로고
    • Nevirapine plasma concentrations are still detectable after more than 2 weeks in the majority of women receiving single-dose nevirapine: Implications for intervention studies
    • Muro, E. P., et al. 2005. Nevirapine plasma concentrations are still detectable after more than 2 weeks in the majority of women receiving single-dose nevirapine: implications for intervention studies. J. Acquir. Immune Defic. Syndr. 39:419-421.
    • (2005) J. Acquir. Immune Defic. Syndr. , vol.39 , pp. 419-421
    • Muro, E.P.1
  • 44
    • 68049121905 scopus 로고    scopus 로고
    • Safety and pharmacokinetics of dapivirine delivery from matrix and reservoir intravaginal rings to HIV-negative women
    • Nel, A., et al. 2009. Safety and pharmacokinetics of dapivirine delivery from matrix and reservoir intravaginal rings to HIV-negative women. J. Acquir. Immune Defic. Syndr. 51:416-423.
    • (2009) J. Acquir. Immune Defic. Syndr. , vol.51 , pp. 416-423
    • Nel, A.1
  • 45
    • 33746930841 scopus 로고    scopus 로고
    • The predominance of human immunodeficiency virus type 1 (HIV-1) circulating recombinant form 02 (CRF02-AG) in West Central Africa may be related to its replicative fitness
    • Njai, H. F., et al. 2006. The predominance of human immunodeficiency virus type 1 (HIV-1) circulating recombinant form 02 (CRF02-AG) in West Central Africa may be related to its replicative fitness. Retrovirology 3:40.
    • (2006) Retrovirology , vol.3 , pp. 40
    • Njai, H.F.1
  • 46
    • 40549106089 scopus 로고    scopus 로고
    • Concentrations of dapivirine in the rhesus macaque and rabbit following once daily intravaginal administration of a gel formulation of [14C]dapivirine for 7 days
    • Nuttall, J. P., et al. 2008. Concentrations of dapivirine in the rhesus macaque and rabbit following once daily intravaginal administration of a gel formulation of [14C]dapivirine for 7 days. Antimicrob. Agents Chemother. 52:909-914.
    • (2008) Antimicrob. Agents Chemother. , vol.52 , pp. 909-914
    • Nuttall, J.P.1
  • 47
    • 34248384307 scopus 로고    scopus 로고
    • Preclinical safety assessments of UC781 antihuman immunodeficiency virus topical microbicide formulations
    • Patton, D. L., et al. 2007. Preclinical safety assessments of UC781 antihuman immunodeficiency virus topical microbicide formulations. Antimicrob. Agents Chemother. 51:1608-1615.
    • (2007) Antimicrob. Agents Chemother. , vol.51 , pp. 1608-1615
    • Patton, D.L.1
  • 49
    • 67649177436 scopus 로고    scopus 로고
    • Plasma efavirenz concentrations and the association with CYP2B6-516G>T polymorphism in HIV-infected Thai children
    • Puthanakit, T., P. Tanpaiboon, L. Aurpibul, T. R. Cressey, and V. Sirisanthana. 2009. Plasma efavirenz concentrations and the association with CYP2B6-516G>T polymorphism in HIV-infected Thai children. Antivir. Ther. 14:315-320.
    • (2009) Antivir. Ther. , vol.14 , pp. 315-320
    • Puthanakit, T.1    Tanpaiboon, P.2    Aurpibul, L.3    Cressey, T.R.4    Sirisanthana, V.5
  • 50
    • 0036971250 scopus 로고    scopus 로고
    • Fitness of drug resistant HIV-1: Methodology and clinical implications
    • Quinones-Mateu, M. E., and E. J. Arts. 2002. Fitness of drug resistant HIV-1: methodology and clinical implications. Drug Resist. Updat. 5:224-233.
    • (2002) Drug Resist. Updat. , vol.5 , pp. 224-233
    • Quinones-Mateu, M.E.1    Arts, E.J.2
  • 51
    • 30644462096 scopus 로고    scopus 로고
    • Virus fitness: Concept, quantification, and application to HIV population dynamics
    • Quinones-Mateu, M. E., and E. J. Arts. 2006. Virus fitness: concept, quantification, and application to HIV population dynamics. Curr. Top. Microbiol. Immunol. 299:83-140.
    • (2006) Curr. Top. Microbiol. Immunol. , vol.299 , pp. 83-140
    • Quinones-Mateu, M.E.1    Arts, E.J.2
  • 52
    • 0001769435 scopus 로고    scopus 로고
    • HIV-1 fitness: Implications for drug resistance, disease progression, and global epidemic evolution
    • C. Kuiken et al. (ed.), Biology and Biophysics Group, Los Alamos National Laboratory, Los Alamos, NM
    • Quiñones-Mateu, M. E., and E. J. Arts. 2001. HIV-1 fitness: implications for drug resistance, disease progression, and global epidemic evolution, p. 134-170. In C. Kuiken et al. (ed.), HIV sequence compendium. Biology and Biophysics Group, Los Alamos National Laboratory, Los Alamos, NM.
    • (2001) HIV Sequence Compendium , pp. 134-170
    • Quiñones-Mateu, M.E.1    Arts, E.J.2
  • 53
    • 0033803642 scopus 로고    scopus 로고
    • A dual infection/competition assay shows a correlation between ex vivo human immunodeficiency virus type 1 fitness and disease progression
    • Quinones-Mateu, M. E., et al. 2000. A dual infection/competition assay shows a correlation between ex vivo human immunodeficiency virus type 1 fitness and disease progression. J. Virol. 74:9222-9233.
    • (2000) J. Virol. , vol.74 , pp. 9222-9233
    • Quinones-Mateu, M.E.1
  • 56
    • 79952115077 scopus 로고    scopus 로고
    • Efavirenz plasma concentrations did not predict cessation of therapy due to neuropsychiatric symptoms in a large randomized trial
    • Read, T. R. H., et al. 2009. Efavirenz plasma concentrations did not predict cessation of therapy due to neuropsychiatric symptoms in a large randomized trial. AIDS 23:2222-2223.
    • (2009) AIDS , vol.23 , pp. 2222-2223
    • Read, T.R.H.1
  • 57
    • 33745158157 scopus 로고
    • A simple method of estimating fifty percent endpoints
    • Lond.
    • Reed, L. J., and H. Muench. 1938. A simple method of estimating fifty percent endpoints. Am. J. Hyg. (Lond.) 27:493-497.
    • (1938) Am. J. Hyg. , vol.27 , pp. 493-497
    • Reed, L.J.1    Muench, H.2
  • 58
    • 77954184672 scopus 로고    scopus 로고
    • Constrained patterns of covariation and clustering of HIV-1 non-nucleoside reverse transcriptase inhibitor resistance mutations
    • Reuman, E. C., S.-Y. Rhee, S. P. Holmes, and R. W. Shafer. 2010. Constrained patterns of covariation and clustering of HIV-1 non-nucleoside reverse transcriptase inhibitor resistance mutations. J. Antimicrob. Chemother. 65:1477-1485.
    • (2010) J. Antimicrob. Chemother. , vol.65 , pp. 1477-1485
    • Reuman, E.C.1    Rhee, S.-Y.2    Holmes, S.P.3    Shafer, R.W.4
  • 60
    • 33751235598 scopus 로고    scopus 로고
    • Genotypic predictors of human immunodeficiency virus type 1 drug resistance
    • Rhee, S. Y., et al. 2006. Genotypic predictors of human immunodeficiency virus type 1 drug resistance. Proc. Natl. Acad. Sci. U. S. A. 103:17355.
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 17355
    • Rhee, S.Y.1
  • 61
    • 66149175684 scopus 로고    scopus 로고
    • Safety and availability of dapivirine (TMC120) delivered from an intravaginal ring
    • Romano, J., et al. 2009. Safety and availability of dapivirine (TMC120) delivered from an intravaginal ring. AIDS Res. Hum. Retroviruses 25:483-488.
    • (2009) AIDS Res. Hum. Retroviruses , vol.25 , pp. 483-488
    • Romano, J.1
  • 62
    • 44449115313 scopus 로고    scopus 로고
    • Development of non-nucleoside reverse transcriptase inhibitors for anti-HIV therapy
    • Sahlberg, C., and X.-X. Zhou. 2008. Development of non-nucleoside reverse transcriptase inhibitors for anti-HIV therapy. Antiinfect. Agents Med. Chem. 7:101-117.
    • (2008) Antiinfect. Agents Med. Chem. , vol.7 , pp. 101-117
    • Sahlberg, C.1    Zhou, X.-X.2
  • 63
    • 67650719145 scopus 로고    scopus 로고
    • Preliminary results from a pharmacokinetic study of the candidate vaginal microbicide agent 1% tenofovir gel
    • abstr. BO11-610
    • Schwartz, J., et al. 2008. Preliminary results from a pharmacokinetic study of the candidate vaginal microbicide agent 1% tenofovir gel, abstr. BO11-610. Microbicides 2008 Conference, New Dehli, India.
    • (2008) Microbicides 2008 Conference, New Dehli, India
    • Schwartz, J.1
  • 64
    • 41149175595 scopus 로고    scopus 로고
    • A randomized six-day safety study of an antiretroviral microbicide candidate UC781, a non-nucleoside reverse transcriptase inhibitor
    • Schwartz, J. L., et al. 2008. A randomized six-day safety study of an antiretroviral microbicide candidate UC781, a non-nucleoside reverse transcriptase inhibitor. Sex. Transm. Dis. 35:414-419.
    • (2008) Sex. Transm. Dis. , vol.35 , pp. 414-419
    • Schwartz, J.L.1
  • 65
    • 33748879209 scopus 로고    scopus 로고
    • Rationale and uses of a public HIV drug-resistance database
    • Shafer, R. W. 2006. Rationale and uses of a public HIV drug-resistance database. J. Infect. Dis. 194:S51-S58.
    • (2006) J. Infect. Dis. , vol.194
    • Shafer, R.W.1
  • 66
    • 38449091906 scopus 로고    scopus 로고
    • Antiretroviral (ARV) drug resistance in the developing world
    • Shekelle, P., et al. 2007. Antiretroviral (ARV) drug resistance in the developing world. Evid. Rep. Technol. Assess. (Full Rep.) 2007:1-74.
    • (2007) Evid. Rep. Technol. Assess. (Full Rep.) , vol.2007 , pp. 1-74
    • Shekelle, P.1
  • 67
    • 57049091723 scopus 로고    scopus 로고
    • Efficacy of Carraguard for prevention of HIV infection in women in South Africa: A randomised, double-blind, placebocontrolled trial
    • Skoler-Karpoff, S., et al. 2008. Efficacy of Carraguard for prevention of HIV infection in women in South Africa: a randomised, double-blind, placebocontrolled trial. Lancet 372:1977-1987.
    • (2008) Lancet , vol.372 , pp. 1977-1987
    • Skoler-Karpoff, S.1
  • 68
    • 15944368905 scopus 로고    scopus 로고
    • Evaluating the potential impact of vaginal microbicides to reduce the risk of acquiring HIV in female sex workers
    • Smith, R. J., E. N. Bodine, D. P. Wilson, and S. M. Blower. 2005. Evaluating the potential impact of vaginal microbicides to reduce the risk of acquiring HIV in female sex workers. AIDS 19:413-421.
    • (2005) AIDS , vol.19 , pp. 413-421
    • Smith, R.J.1    Bodine, E.N.2    Wilson, D.P.3    Blower, S.M.4
  • 69
    • 78751693777 scopus 로고    scopus 로고
    • In vitro selection and characterization of viruses resistant to R1206, a novel non-nucleoside reverse transcriptase inhibitor
    • Su, G., et al. 2007. In vitro selection and characterization of viruses resistant to R1206, a novel non-nucleoside reverse transcriptase inhibitor. Antivir. Ther. 12:S35.
    • (2007) Antivir. Ther. , vol.12 , pp. 35
    • Su, G.1
  • 70
    • 48749086467 scopus 로고    scopus 로고
    • Enhancement of HIV infection by cellulose sulfate
    • Tao, W., C. Richards, and D. Hamer. 2008. Enhancement of HIV infection by cellulose sulfate. AIDS Res. Hum. Retroviruses 24:925-929.
    • (2008) AIDS Res. Hum. Retroviruses , vol.24 , pp. 925-929
    • Tao, W.1    Richards, C.2    Hamer, D.3
  • 71
    • 34547480469 scopus 로고    scopus 로고
    • In vitro pre- and post-exposure prophylaxis using HIV inhibitors as microbicides against cell-free or cell-associated HIV-1 infection
    • Terrazas-Aranda, K., Y. Van Herrewege, P. J. Lewi, J. Van Roey, and G. Vanham. 2007. In vitro pre- and post-exposure prophylaxis using HIV inhibitors as microbicides against cell-free or cell-associated HIV-1 infection. Antivir. Chem. Chemother. 18:141-151.
    • (2007) Antivir. Chem. Chemother. , vol.18 , pp. 141-151
    • Terrazas-Aranda, K.1    Van Herrewege, Y.2    Lewi, P.J.3    Van Roey, J.4    Vanham, G.5
  • 72
    • 7544231718 scopus 로고    scopus 로고
    • Diminished representation of HIV-1 variants containing select drug resistance-conferring mutations in primary HIV-1 infection
    • Turner, D. M. D., et al. 2004. Diminished representation of HIV-1 variants containing select drug resistance-conferring mutations in primary HIV-1 infection. J. Acquir. Immune Defic. Syndr. 37:1627-1631.
    • (2004) J. Acquir. Immune Defic. Syndr. , vol.37 , pp. 1627-1631
    • Turner, D.M.D.1
  • 73
    • 77951065603 scopus 로고    scopus 로고
    • UNAIDS. UNAIDS/09.36E/JC1700E. UNAIDS, Geneva, Switzerland
    • UNAIDS. 2009. AIDS epidemic update: November 2009. UNAIDS/09.36E/JC1700E. UNAIDS, Geneva, Switzerland.
    • (2009) AIDS Epidemic Update: November 2009
  • 74
    • 48249154985 scopus 로고    scopus 로고
    • Lack of effectiveness of cellulose sulfate gel for the prevention of vaginal HIV transmission
    • Van Damme, L., et al. 2008. Lack of effectiveness of cellulose sulfate gel for the prevention of vaginal HIV transmission. N. Engl. J. Med. 359:463-472.
    • (2008) N. Engl. J. Med. , vol.359 , pp. 463-472
    • Van Damme, L.1
  • 75
    • 0347992022 scopus 로고    scopus 로고
    • In vitro evaluation of nonnucleoside reverse transcriptase inhibitors UC-781 and TMC120-R147681 as human immunodeficiency virus microbicides
    • Van Herrewege, Y., et al. 2004. In vitro evaluation of nonnucleoside reverse transcriptase inhibitors UC-781 and TMC120-R147681 as human immunodeficiency virus microbicides. Antimicrob. Agents Chemother. 48:337-339.
    • (2004) Antimicrob. Agents Chemother. , vol.48 , pp. 337-339
    • Van Herrewege, Y.1
  • 77
    • 0036470984 scopus 로고    scopus 로고
    • Resistance to antiretroviral treatment in Gabon: Need for implementation of guidelines on antiretroviral therapy use and HIV-1 drug resistance monitoring in developing countries
    • Vergne, L., et al. 2002. Resistance to antiretroviral treatment in Gabon: need for implementation of guidelines on antiretroviral therapy use and HIV-1 drug resistance monitoring in developing countries. J. Acquir. Immune Defic. Syndr. 29:165-168.
    • (2002) J. Acquir. Immune Defic. Syndr. , vol.29 , pp. 165-168
    • Vergne, L.1
  • 79
    • 77649254869 scopus 로고    scopus 로고
    • Resistance profile of etravirine: Combined analysis of baseline genotypic and phenotypic data from the randomized, controlled phase III clinical studies
    • Vingerhoets, J., et al. 2010. Resistance profile of etravirine: combined analysis of baseline genotypic and phenotypic data from the randomized, controlled phase III clinical studies. AIDS 24:503.
    • (2010) AIDS , vol.24 , pp. 503
    • Vingerhoets, J.1
  • 80
    • 68649117176 scopus 로고    scopus 로고
    • Safety, tolerability, and systemic absorption of dapivirine vaginal microbicide gel in healthy, HIV-negative women
    • Vyankandondera, J., et al. 2009. Safety, tolerability, and systemic absorption of dapivirine vaginal microbicide gel in healthy, HIV-negative women. AIDS 23:1531-1538.
    • (2009) AIDS , vol.23 , pp. 1531-1538
    • Vyankandondera, J.1
  • 81
    • 0042405174 scopus 로고    scopus 로고
    • A novel TaqMan real-time PCR assay to estimate ex vivo human immunodeficiency virus type 1 fitness in the era of multi-target (pol and env) antiretroviral therapy
    • Weber, J., et al. 2003. A novel TaqMan real-time PCR assay to estimate ex vivo human immunodeficiency virus type 1 fitness in the era of multi-target (pol and env) antiretroviral therapy. J. Gen. Virol. 84:2217-2228.
    • (2003) J. Gen. Virol. , vol.84 , pp. 2217-2228
    • Weber, J.1
  • 82
    • 79953226066 scopus 로고    scopus 로고
    • Resistance analysis to maturation, protease, reverse transcriptase and integrase inhibitors based on 3′Gag(p2/p7/p1/p6)/PR/RT/INT-recombinant viruses: A useful tool in the multi-target era of antiretroviral drugs
    • Weber, J., et al. 2010. Resistance analysis to maturation, protease, reverse transcriptase and integrase inhibitors based on 3′Gag(p2/p7/p1/p6) /PR/RT/INT-recombinant viruses: a useful tool in the multi-target era of antiretroviral drugs. Antivir. Ther. 14:A127.
    • (2010) Antivir. Ther. , vol.14
    • Weber, J.1
  • 83
    • 79953188867 scopus 로고    scopus 로고
    • Resistance mutations in protease, reverse transcriptase, and integrase genes: Do they have an epistatic effect on drug susceptibility and/or HIV-1 replicative fitness?
    • Weber, J., et al. 2010. Resistance mutations in protease, reverse transcriptase, and integrase genes: do they have an epistatic effect on drug susceptibility and/or HIV-1 replicative fitness? Antivir. Ther. 15:A94.
    • (2010) Antivir. Ther. , vol.15
    • Weber, J.1
  • 84
    • 33745886803 scopus 로고    scopus 로고
    • Use of a novel assay based on intact recombinant viruses expressing green (EGFP) or red (DsRed2) fluorescent proteins to examine the contribution of pol and env genes to overall HIV-1 replicative fitness
    • DOI 10.1016/j.jviromet.2006.04.004, PII S0166093406001297
    • Weber, J., et al. 2006. Use of a novel assay based on intact recombinant viruses expressing green (EGFP) or red (DsRed2) fluorescent proteins to examine the contribution of pol and env genes to overall HIV-1 replicative fitness. J. Virol. Methods 136:102-117. (Pubitemid 44051582)
    • (2006) Journal of Virological Methods , vol.136 , Issue.1-2 , pp. 102-117
    • Weber, J.1    Weberova, J.2    Carobene, M.3    Mirza, M.4    Martinez-Picado, J.5    Kazanjian, P.6    Quinones-Mateu, M.E.7
  • 86
    • 47649123409 scopus 로고    scopus 로고
    • The paradoxical effects of using antiretroviral-based microbicides to control HIV epidemics
    • Wilson, D. P., P. M. Coplan, M. A. Wainberg, and S. M. Blower. 2008. The paradoxical effects of using antiretroviral-based microbicides to control HIV epidemics. Proc. Natl. Acad. Sci. U. S. A. 105:9835-9840.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 9835-9840
    • Wilson, D.P.1    Coplan, P.M.2    Wainberg, M.A.3    Blower, S.M.4
  • 87
    • 77952606637 scopus 로고    scopus 로고
    • The M230L nonnucleoside reverse transcriptase inhibitor resistance mutation in HIV-1 reverse transcriptase impairs enzymatic function and viral replicative capacity
    • Xu, H.-T., et al. 2010. The M230L nonnucleoside reverse transcriptase inhibitor resistance mutation in HIV-1 reverse transcriptase impairs enzymatic function and viral replicative capacity. Antimicrob. Agents Chemother. 54:2401-2408.
    • (2010) Antimicrob. Agents Chemother. , vol.54 , pp. 2401-2408
    • Xu, H.-T.1
  • 88
    • 3042734981 scopus 로고    scopus 로고
    • Infrequent transmission of HIV-1 drug-resistant variants
    • Yerly, S., et al. 2004. Infrequent transmission of HIV-1 drug-resistant variants. Antivir. Ther. 9:375-384.
    • (2004) Antivir. Ther. , vol.9 , pp. 375-384
    • Yerly, S.1
  • 89
    • 33846637261 scopus 로고    scopus 로고
    • A novel nonnucleoside analogue that inhibits human immunodeficiency virus type 1 isolates resistant to current nonnucleoside reverse transcriptase inhibitors
    • Zhang, Z., et al. 2007. A novel nonnucleoside analogue that inhibits human immunodeficiency virus type 1 isolates resistant to current nonnucleoside reverse transcriptase inhibitors. Antimicrob. Agents Chemother. 51:429-437.
    • (2007) Antimicrob. Agents Chemother. , vol.51 , pp. 429-437
    • Zhang, Z.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.