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Volumn 10, Issue 2, 2013, Pages 170-176

Targeted overexpression of CKI-insensitive cyclin-dependent kinase 4 increases functional β-cell number through enhanced self-replication in zebrafish

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR; INSULIN; ZEBRAFISH PROTEIN;

EID: 84878861446     PISSN: 15458547     EISSN: None     Source Type: Journal    
DOI: 10.1089/zeb.2012.0816     Document Type: Article
Times cited : (7)

References (45)
  • 2
    • 53549094111 scopus 로고    scopus 로고
    • Relationship between beta-cell mass and diabetes onset
    • Matveyenko AV, Butler PC. Relationship between beta-cell mass and diabetes onset. Diabetes Obes Metab 2008;10: 23-31.
    • (2008) Diabetes Obes Metab , vol.10 , pp. 23-31
    • Matveyenko, A.V.1    Butler, P.C.2
  • 3
    • 24944591025 scopus 로고    scopus 로고
    • New sources of pancreatic betacells
    • Bonner-Weir S, Weir GC. New sources of pancreatic betacells. Nat Biotechnol 2005;23:857-861.
    • (2005) Nat Biotechnol , vol.23 , pp. 857-861
    • Bonner-Weir, S.1    Weir, G.C.2
  • 5
    • 53349178722 scopus 로고    scopus 로고
    • In vivo reprogramming of adult pancreatic exocrine cells to beta-cells
    • Zhou Q, Brown J, Kanarek A, Rajagopal J, Melton DA. In vivo reprogramming of adult pancreatic exocrine cells to beta-cells. Nature 2008;455:627-632.
    • (2008) Nature , vol.455 , pp. 627-632
    • Zhou, Q.1    Brown, J.2    Kanarek, A.3    Rajagopal, J.4    Melton, D.A.5
  • 6
    • 38749108893 scopus 로고    scopus 로고
    • Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas
    • Xu X, D'Hoker J, Stange G, et al. Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas. Cell 2008;132:197-207.
    • (2008) Cell , vol.132 , pp. 197-207
    • Xu, X.1    D'Hoker, J.2    Stange, G.3
  • 8
    • 33845513370 scopus 로고    scopus 로고
    • P27 Regulates the transition of betacells from quiescence to proliferation
    • Georgia S, Bhushan A. p27 Regulates the transition of betacells from quiescence to proliferation. Diabetes 2006;55: 2950-2956.
    • (2006) Diabetes , vol.55 , pp. 2950-2956
    • Georgia, S.1    Bhushan, A.2
  • 9
    • 34247644369 scopus 로고    scopus 로고
    • Growth and regeneration of adult beta cells does not involve specialized progenitors
    • Teta M, Rankin MM, Long SY, Stein GM, Kushner JA. Growth and regeneration of adult beta cells does not involve specialized progenitors. Dev Cell 2007;12:817-826.
    • (2007) Dev Cell , vol.12 , pp. 817-826
    • Teta, M.1    Rankin, M.M.2    Long, S.Y.3    Stein, G.M.4    Kushner, J.A.5
  • 10
    • 0030903840 scopus 로고    scopus 로고
    • Apoptosis participates in the remodeling of the endocrine pancreas in the neonatal rat
    • Scaglia L, Cahill CJ, Finegood DT, Bonner-Weir S. Apoptosis participates in the remodeling of the endocrine pancreas in the neonatal rat. Endocrinology 1997;138: 1736-1741.
    • (1997) Endocrinology , vol.138 , pp. 1736-1741
    • Scaglia, L.1    Cahill, C.J.2    Finegood, D.T.3    Bonner-Weir, S.4
  • 11
    • 77952668617 scopus 로고    scopus 로고
    • Validation of different replication markers for the detection of beta-cell proliferation in human pancreatic tissue
    • Kohler CU, Kreuter A, Rozynkowski MC, et al. Validation of different replication markers for the detection of beta-cell proliferation in human pancreatic tissue. Regul Pept 2010; 162:115-121.
    • (2010) Regul Pept , vol.162 , pp. 115-121
    • Kohler, C.U.1    Kreuter, A.2    Rozynkowski, M.C.3
  • 13
    • 0028987251 scopus 로고
    • Dynamics of betacell mass in the growing rat pancreas. Estimation with a simple mathematical model
    • Finegood DT, Scaglia L, Bonner-Weir S. Dynamics of betacell mass in the growing rat pancreas. Estimation with a simple mathematical model. Diabetes 1995;44:249-256.
    • (1995) Diabetes , vol.44 , pp. 249-256
    • Finegood, D.T.1    Scaglia, L.2    Bonner-Weir, S.3
  • 14
    • 65249093055 scopus 로고    scopus 로고
    • Polycomb protein Ezh2 regulates pancreatic beta-cell Ink4a/Arf expression and regeneration in diabetes mellitus
    • Chen H, Gu X, Su IH, et al. Polycomb protein Ezh2 regulates pancreatic beta-cell Ink4a/Arf expression and regeneration in diabetes mellitus. Genes Dev 2009;23:975-985.
    • (2009) Genes Dev , vol.23 , pp. 975-985
    • Chen, H.1    Gu, X.2    Su, I.H.3
  • 15
    • 65249121864 scopus 로고    scopus 로고
    • Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation
    • Dhawan S, Tschen SI, Bhushan A. Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation. Genes Dev 2009;23:906-911.
    • (2009) Genes Dev , vol.23 , pp. 906-911
    • Dhawan, S.1    Tschen, S.I.2    Bhushan, A.3
  • 16
    • 66449093171 scopus 로고    scopus 로고
    • Minireview: Meeting the demand for insulin: Molecular mechanisms of adaptive postnatal beta-cell mass expansion
    • Sachdeva MM, Stoffers DA. Minireview: Meeting the demand for insulin: Molecular mechanisms of adaptive postnatal beta-cell mass expansion. Mol Endocrinol 2009;23: 747-758.
    • (2009) Mol Endocrinol , vol.23 , pp. 747-758
    • Sachdeva, M.M.1    Stoffers, D.A.2
  • 17
    • 12344323484 scopus 로고    scopus 로고
    • Type 2 diabetes - A matter of beta-cell life and death?
    • Rhodes CJ. Type 2 diabetes - A matter of beta-cell life and death? Science 2005;307:380-384.
    • (2005) Science , vol.307 , pp. 380-384
    • Rhodes, C.J.1
  • 18
    • 84866609793 scopus 로고    scopus 로고
    • Nutrient excess stimulates beta-cell neogenesis in zebrafish
    • Maddison LA, Chen W. Nutrient excess stimulates beta-cell neogenesis in zebrafish. Diabetes 2012;61:2517-2524.
    • (2012) Diabetes , vol.61 , pp. 2517-2524
    • Maddison, L.A.1    Chen, W.2
  • 19
    • 70349292206 scopus 로고    scopus 로고
    • Distinct populations of quiescent and proliferative pancreatic betacells identified by HOTcre mediated labeling
    • Hesselson D, Anderson RM, Beinat M, Stainier DY. Distinct populations of quiescent and proliferative pancreatic betacells identified by HOTcre mediated labeling. Proc Natl Acad Sci USA 2009;106:14896-14901.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 14896-14901
    • Hesselson, D.1    Anderson, R.M.2    Beinat, M.3    Stainier, D.Y.4
  • 22
    • 84862001481 scopus 로고    scopus 로고
    • Adenosine signaling promotes regeneration of pancreatic beta cells in vivo
    • Andersson O, Adams BA, Yoo D, et al. Adenosine signaling promotes regeneration of pancreatic beta cells in vivo. Cell Metab 2012;15:885-894.
    • (2012) Cell Metab , vol.15 , pp. 885-894
    • Andersson, O.1    Adams, B.A.2    Yoo, D.3
  • 23
    • 79955430577 scopus 로고    scopus 로고
    • Suppression of Ptf1a activity induces acinar-to-endocrine conversion
    • Hesselson D, Anderson RM, Stainier DY. Suppression of Ptf1a activity induces acinar-to-endocrine conversion. Curr Biol 2011;21:712-717.
    • (2011) Curr Biol , vol.21 , pp. 712-717
    • Hesselson, D.1    Anderson, R.M.2    Stainier, D.Y.3
  • 25
    • 80055118585 scopus 로고    scopus 로고
    • Endocrine pancreas development in zebrafish
    • Tehrani Z, Lin S. Endocrine pancreas development in zebrafish. Cell Cycle 2011;10:3466-3472.
    • (2011) Cell Cycle , vol.10 , pp. 3466-3472
    • Tehrani, Z.1    Lin, S.2
  • 26
    • 78649478117 scopus 로고    scopus 로고
    • Molecular regulation of pancreas development in zebrafish
    • Kimmel RA, Meyer D. Molecular regulation of pancreas development in zebrafish. Methods Cell Biol 2010;100: 261-280.
    • (2010) Methods Cell Biol , vol.100 , pp. 261-280
    • Kimmel, R.A.1    Meyer, D.2
  • 27
    • 0034903133 scopus 로고    scopus 로고
    • Zebrafish pdx1 morphant displays defects in pancreas development and digestive organ chirality, and potentially identifies a multipotent pancreas progenitor cell
    • Yee NS, Yusuff S, Pack M. Zebrafish pdx1 morphant displays defects in pancreas development and digestive organ chirality, and potentially identifies a multipotent pancreas progenitor cell. Genesis 2001;30:137-140.
    • (2001) Genesis , vol.30 , pp. 137-140
    • Yee, N.S.1    Yusuff, S.2    Pack, M.3
  • 29
    • 0029664339 scopus 로고    scopus 로고
    • Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma
    • Zuo L, Weger J, Yang Q, et al. Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma. Nat Genet 1996;12:97-99.
    • (1996) Nat Genet , vol.12 , pp. 97-99
    • Zuo, L.1    Weger, J.2    Yang, Q.3
  • 30
    • 0028978274 scopus 로고
    • A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma
    • Wolfel T, Hauer M, Schneider J, et al. A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma. Science 1995;269:1281-1284.
    • (1995) Science , vol.269 , pp. 1281-1284
    • Wolfel, T.1    Hauer, M.2    Schneider, J.3
  • 31
    • 0347383875 scopus 로고    scopus 로고
    • Characterization of the abnormal pancreatic development, reduced growth and infertility in Cdk4 mutant mice
    • Mettus RV, Rane SG. Characterization of the abnormal pancreatic development, reduced growth and infertility in Cdk4 mutant mice. Oncogene 2003;22:8413-8421.
    • (2003) Oncogene , vol.22 , pp. 8413-8421
    • Mettus, R.V.1    Rane, S.G.2
  • 32
    • 0032937751 scopus 로고    scopus 로고
    • Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia
    • Rane SG, Dubus P, Mettus RV, et al. Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia. Nat Genet 1999;22:44-52.
    • (1999) Nat Genet , vol.22 , pp. 44-52
    • Rane, S.G.1    Dubus, P.2    Mettus, R.V.3
  • 33
    • 79955557616 scopus 로고    scopus 로고
    • The Cdk4-E2f1 pathway regulates early pancreas development by targeting Pdx1 + progenitors and Ngn3 + endocrine precursors
    • Kim SY, Rane SG. The Cdk4-E2f1 pathway regulates early pancreas development by targeting Pdx1 + progenitors and Ngn3 + endocrine precursors. Development 2011;138:1903- 1912.
    • (2011) Development , vol.138 , pp. 1903-1912
    • Kim, S.Y.1    Rane, S.G.2
  • 34
    • 68249090581 scopus 로고    scopus 로고
    • The CDK4-pRBE2F1 pathway controls insulin secretion
    • Annicotte JS, Blanchet E, Chavey C, et al. The CDK4-pRBE2F1 pathway controls insulin secretion. Nat Cell Biol 2009; 11:1017-1023.
    • (2009) Nat Cell Biol , vol.11 , pp. 1017-1023
    • Annicotte, J.S.1    Blanchet, E.2    Chavey, C.3
  • 35
    • 10944261816 scopus 로고    scopus 로고
    • In vivo proliferation of differentiated pancreatic islet beta cells in transgenic mice expressing mutated cyclin-dependent kinase 4
    • Hino S, Yamaoka T, Yamashita Y, Yamada T, Hata J, Itakura M. In vivo proliferation of differentiated pancreatic islet beta cells in transgenic mice expressing mutated cyclin-dependent kinase 4. Diabetologia 2004;47:1819-1830.
    • (2004) Diabetologia , vol.47 , pp. 1819-1830
    • Hino, S.1    Yamaoka, T.2    Yamashita, Y.3    Yamada, T.4    Hata, J.5    Itakura, M.6
  • 37
    • 82555168325 scopus 로고    scopus 로고
    • Visualizing digestive organ morphology and function using differential fatty acid metabolism in live zebrafish
    • Carten JD, Bradford MK, Farber SA. Visualizing digestive organ morphology and function using differential fatty acid metabolism in live zebrafish. Dev Biol 2011;360:276-285.
    • (2011) Dev Biol , vol.360 , pp. 276-285
    • Carten, J.D.1    Bradford, M.K.2    Farber, S.A.3
  • 38
    • 0036118368 scopus 로고    scopus 로고
    • Enumeration of the simian virus 40 early region elements necessary for human cell transformation
    • Hahn WC, Dessain SK, Brooks MW, et al. Enumeration of the simian virus 40 early region elements necessary for human cell transformation. Mol Cell Biol 2002;22:2111-2123.
    • (2002) Mol Cell Biol , vol.22 , pp. 2111-2123
    • Hahn, W.C.1    Dessain, S.K.2    Brooks, M.W.3
  • 39
    • 36448963734 scopus 로고    scopus 로고
    • The Tol2kit: A multisite gateway-based construction kit for Tol2 transposon transgenesis constructs
    • Kwan KM, Fujimoto E, Grabher C, et al. The Tol2kit: A multisite gateway-based construction kit for Tol2 transposon transgenesis constructs. Dev Dyn 2007;236:3088-3099.
    • (2007) Dev Dyn , vol.236 , pp. 3088-3099
    • Kwan, K.M.1    Fujimoto, E.2    Grabher, C.3
  • 40
    • 33750433896 scopus 로고    scopus 로고
    • Functional dissection of the Tol2 transposable element identified the minimal cissequence and a highly repetitive sequence in the subterminal region essential for transposition
    • Urasaki A, Morvan G, Kawakami K. Functional dissection of the Tol2 transposable element identified the minimal cissequence and a highly repetitive sequence in the subterminal region essential for transposition. Genetics 2006;174:639-649.
    • (2006) Genetics , vol.174 , pp. 639-649
    • Urasaki, A.1    Morvan, G.2    Kawakami, K.3
  • 41
    • 0028080878 scopus 로고
    • Suppression of cyclin-dependent kinase 4 during induced differentiation of erythroleukemia cells
    • Kiyokawa H, Richon VM, Rifkind RA, Marks PA. Suppression of cyclin-dependent kinase 4 during induced differentiation of erythroleukemia cells. Mol Cell Biol 1994;14:7195-203.
    • (1994) Mol Cell Biol , vol.14 , pp. 7195-7203
    • Kiyokawa, H.1    Richon, V.M.2    Rifkind, R.A.3    Marks, P.A.4
  • 43
    • 77953646514 scopus 로고    scopus 로고
    • Blood sugar measurement in zebrafish reveals dynamics of glucose homeostasis
    • Eames SC, Philipson LH, Prince VE, Kinkel MD. Blood sugar measurement in zebrafish reveals dynamics of glucose homeostasis. Zebrafish 2010;7:205-213.
    • (2010) Zebrafish , vol.7 , pp. 205-213
    • Eames, S.C.1    Philipson, L.H.2    Prince, V.E.3    Kinkel, M.D.4
  • 44
    • 2342510386 scopus 로고    scopus 로고
    • Adult pancreatic beta-cells are formed by self-duplication rather than stemcell differentiation
    • Dor Y, Brown J, Martinez OI, Melton DA. Adult pancreatic beta-cells are formed by self-duplication rather than stemcell differentiation. Nature 2004;429:41-46.
    • (2004) Nature , vol.429 , pp. 41-46
    • Dor, Y.1    Brown, J.2    Martinez, O.I.3    Melton, D.A.4
  • 45
    • 27544453375 scopus 로고    scopus 로고
    • A network of genetic events sufficient to convert normal human cells to a tumorigenic state
    • Kendall SD, Linardic CM, Adam SJ, Counter CM. A network of genetic events sufficient to convert normal human cells to a tumorigenic state. Cancer Res 2005;65:9824-9828.
    • (2005) Cancer Res , vol.65 , pp. 9824-9828
    • Kendall, S.D.1    Linardic, C.M.2    Adam, S.J.3    Counter, C.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.