Distinct patterns of APP processing in the CNS in autosomal-dominant and sporadic Alzheimer disease

Acta Neuropathologica

Volumn 125, Issue 2, 2013, Pages 201-213

  Pera, Marta ^a,b   Alcolea, Daniel ^a,b   Sánchez Valle, Raquel ^c   Guardia Laguarta, Cristina ^a,b   Colom Cadena, Martí ^a,b   Badiola, Nahuai ^a,b   Suárez Calvet, Marc ^a,b   Lladó, Albert ^c   Barrera Ocampo, Alvaro A ^d,e   Sepulveda Falla, Diego ^d,e   Blesa, Rafael ^a,b   Molinuevo, José L ^c   Clarimón, Jordi ^a,b   Ferrer, Isidre ^b,f   Gelpi, Ellen ^g   Lleó, Alberto ^a,b  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED SOBRE ENFERMEDADES NEURODEGENERATIVAS CIBERNED   (Spain)

^c HOSPITAL CLÍNIC   (Spain)

^d UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^e UNIVERSIDAD DE ANTIOQUIA   (Colombia)

^f UNIVERSITY OF BARCELONA   (Spain)

^g INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

Author keywords

Amyloid; Site APP cleaving enzyme; Amyloid precursor protein; Autosomal dominant Alzheimer disease; Presenilin

Indexed keywords

AMYLOID PRECURSOR PROTEIN; AMYLOID PRECURSOR PROTEIN ALPHA; AMYLOID PRECURSOR PROTEIN BETA CARBOXY TERMINAL FRAGMENT; BETA SECRETASE; PRESENILIN 1; PROTEIN PRECURSOR; UNCLASSIFIED DRUG;

ADULT; AGED; ALZHEIMER DISEASE; AMYLOID PLAQUE; AMYLOID PRECURSOR GENE; ARTICLE; AUTOSOMAL DOMINANT ALZHEIMER DISEASE; BRAIN LEVEL; CARBOXY TERMINAL SEQUENCE; CENTRAL NERVOUS SYSTEM; CEREBROSPINAL FLUID EXAMINATION; CLINICAL ARTICLE; CONTROLLED STUDY; DYSTROPHY; ENZYME ACTIVITY; FEMALE; GENE MUTATION; HETEROZYGOTE; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; MALE; MOLECULAR PATHOLOGY; NEURITE; PRESENILIN 1 GENE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROCESSING; PROTEIN SYNTHESIS; SPORADIC ALZHEIMER DISEASE;

ADULT; AGED; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; APOLIPOPROTEINS E; ASPARTIC ACID ENDOPEPTIDASES; BLOTTING, WESTERN; CENTRAL NERVOUS SYSTEM; FEMALE; HETEROZYGOTE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MUTATION; NEURITES; PRESENILIN-1;

EID: 84878840263     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-012-1062-9     Document Type: Article

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