-
1
-
-
27244452986
-
Genetics of myeloid malignancies: Pathogenetic and clinical implications
-
Frohling S, Scholl C, Gilliland DG, Levine RL. Genetics of myeloid malignancies: pathogenetic and clinical implications. J Clin Oncol. 2005;23:6285-95.
-
(2005)
J Clin Oncol
, vol.23
, pp. 6285-6295
-
-
Frohling, S.1
Scholl, C.2
Gilliland, D.G.3
Levine, R.L.4
-
2
-
-
33751267902
-
Acute myeloid leukaemia
-
Estey E, Dohner H. Acute myeloid leukaemia. Lancet. 2006;368: 1894-907.
-
(2006)
Lancet
, vol.368
, pp. 1894-1907
-
-
Estey, E.1
Dohner, H.2
-
3
-
-
80052384568
-
Deregulated transcription factors in leukemia
-
Shima Y, Kitabayashi I. Deregulated transcription factors in leukemia. Int J Hematol. 2011;94:134-41.
-
(2011)
Int J Hematol
, vol.94
, pp. 134-141
-
-
Shima, Y.1
Kitabayashi, I.2
-
4
-
-
2942516037
-
The 8;21 translocation in leukemogenesis
-
Peterson LF, Zhang DE. The 8;21 translocation in leukemogenesis. Oncogene. 2004;23:4255-62.
-
(2004)
Oncogene
, vol.23
, pp. 4255-4262
-
-
Peterson, L.F.1
Zhang, D.E.2
-
5
-
-
19944431253
-
AML1-ETO and C-KIT mutation/overexpression in t(8;21) leukemia: Implication in stepwise leukemogenesis and response to Gleevec
-
Wang YY, Zhou GB, Yin T, Chen B, Shi JY, Liang WX, et al. AML1-ETO and C-KIT mutation/overexpression in t(8;21) leukemia: implication in stepwise leukemogenesis and response to Gleevec. Proc Natl Acad Sci USA. 2005;102:1104-9.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 1104-1109
-
-
Wang, Y.Y.1
Zhou, G.B.2
Yin, T.3
Chen, B.4
Shi, J.Y.5
Liang, W.X.6
-
6
-
-
0037062350
-
PML/RARalpha and FLT3-ITD induce an APL like disease in a mouse model
-
Kelly LM, Kutok JL, Williams IR, Boulton CL, Amaral SM, Curley DP, et al. PML/RARalpha and FLT3-ITD induce an AP Llike disease in a mouse model. Proc Natl Acad Sci USA. 2002;99: 8283-8.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 8283-8288
-
-
Kelly, L.M.1
Kutok, J.L.2
Williams, I.R.3
Boulton, C.L.4
Amaral, S.M.5
Curley, D.P.6
-
7
-
-
0036636857
-
Core-binding factors in haematopoiesis and leukaemia
-
Speck NA, Gilliland DG. Core-binding factors in haematopoiesis and leukaemia. Nat Rev Cancer. 2002;2:502-13.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 502-513
-
-
Speck, N.A.1
Gilliland, D.G.2
-
8
-
-
73949090504
-
AML1/RUNX1 mutations in 470 adult patients with de novo acute myeloid leukemia: Prognostic implication and interaction with other gene alterations
-
Tang JL, Hou HA, Chen CY, Liu CY, Chou WC, Tseng MH, et al. AML1/RUNX1 mutations in 470 adult patients with de novo acute myeloid leukemia: prognostic implication and interaction with other gene alterations. Blood. 2009;114:5352-61.
-
(2009)
Blood
, vol.114
, pp. 5352-5361
-
-
Tang, J.L.1
Hou, H.A.2
Chen, C.Y.3
Liu, C.Y.4
Chou, W.C.5
Tseng, M.H.6
-
9
-
-
63849241865
-
Double CEBPA mutations, but not single CEBPA mutations, define a subgroup of acute myeloid leukemia with a distinctive gene expression profile that is uniquely associated with a favorable outcome
-
Wouters BJ, Lowenberg B, Erpelinck-Verschueren CA, van Putten WL, Valk PJ, Delwel R. Double CEBPA mutations, but not single CEBPA mutations, define a subgroup of acute myeloid leukemia with a distinctive gene expression profile that is uniquely associated with a favorable outcome. Blood. 2009;113:3088-91.
-
(2009)
Blood
, vol.113
, pp. 3088-3091
-
-
Wouters, B.J.1
Lowenberg, B.2
Erpelinck-Verschueren, C.A.3
Van, P.W.L.4
Valk, P.J.5
Delwel, R.6
-
10
-
-
59149096563
-
Dysregulation of the C/EBPalpha differentiation pathway in human cancer
-
Koschmieder S, Halmos B, Levantini E, Tenen DG. Dysregulation of the C/EBPalpha differentiation pathway in human cancer. J Clin Oncol. 2009;27:619-28.
-
(2009)
J Clin Oncol
, vol.27
, pp. 619-628
-
-
Koschmieder, S.1
Halmos, B.2
Levantini, E.3
Tenen, D.G.4
-
11
-
-
79952092487
-
Molecular genetics of adult acute myeloid leukemia: Prognostic and therapeutic implications
-
Marcucci G, Haferlach T, Dohner H. Molecular genetics of adult acute myeloid leukemia: prognostic and therapeutic implications. J Clin Oncol. 2011;29:475-86.
-
(2011)
J Clin Oncol
, vol.29
, pp. 475-486
-
-
Marcucci, G.1
Haferlach, T.2
Dohner, H.3
-
12
-
-
0024990090
-
N-ras mutations in adult de novo acute myelogenous leukemia: Prevalence and clinical significance
-
Radich JP, Kopecky KJ, Willman CL, Weick J, Head D, Appelbaum F, et al. N-ras mutations in adult de novo acute myelogenous leukemia: prevalence and clinical significance. Blood. 1990;76:801-7.
-
(1990)
Blood
, vol.76
, pp. 801-807
-
-
Radich, J.P.1
Kopecky, K.J.2
Willman, C.L.3
Weick, J.4
Head, D.5
Appelbaum, F.6
-
13
-
-
0028214608
-
Prognostic importance of mutations in the ras proto-oncogenes in de novo acute myeloid leukemia
-
Neubauer A, Dodge RK, George SL, Davey FR, Silver RT, Schiffer CA, et al. Prognostic importance of mutations in the ras proto-oncogenes in de novo acute myeloid leukemia. Blood. 1994;83:1603-11.
-
(1994)
Blood
, vol.83
, pp. 1603-1611
-
-
Neubauer, A.1
Dodge, R.K.2
George, S.L.3
Davey, F.R.4
Silver, R.T.5
Schiffer, C.A.6
-
14
-
-
0030451722
-
Internal tandem duplication of the FLT3 gene found in acute myeloid leukemia
-
Nakao M, Yokota S, Iwai T, Kaneko H, Horiike S, Kashima K, et al. Internal tandem duplication of the FLT3 gene found in acute myeloid leukemia. Leukemia. 1996;10:1911-8.
-
(1996)
Leukemia
, vol.10
, pp. 1911-1918
-
-
Nakao, M.1
Yokota, S.2
Iwai, T.3
Kaneko, H.4
Horiike, S.5
Kashima, K.6
-
15
-
-
0033134792
-
Prognostic implication of FLT3 and N-RAS gene mutations in acute myeloid leukemia
-
Kiyoi H, Naoe T, Nakano Y, Yokota S, Minami S, Miyawaki S, et al. Prognostic implication of FLT3 and N-RAS gene mutations in acute myeloid leukemia. Blood. 1999;93:3074-80.
-
(1999)
Blood
, vol.93
, pp. 3074-3080
-
-
Kiyoi, H.1
Naoe, T.2
Nakano, Y.3
Yokota, S.4
Minami, S.5
Miyawaki, S.6
-
16
-
-
0035871889
-
Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies
-
Yamamoto Y, Kiyoi H, Nakano Y, Suzuki R, Kodera Y, Miyawaki S, et al. Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies. Blood. 2001;97:2434-9.
-
(2001)
Blood
, vol.97
, pp. 2434-2439
-
-
Yamamoto, Y.1
Kiyoi, H.2
Nakano, Y.3
Suzuki, R.4
Kodera, Y.5
Miyawaki, S.6
-
17
-
-
48749121814
-
Core binding factor acute myeloid leukemia
-
Paschka P. Core binding factor acute myeloid leukemia. Semin Oncol. 2008;35:410-7.
-
(2008)
Semin Oncol
, vol.35
, pp. 410-417
-
-
Paschka, P.1
-
18
-
-
0034650957
-
C-kit mutations in core binding factor leukemias
-
Beghini A, Peterlongo P, Ripamonti CB, Larizza L, Cairoli R, Morra E, et al. C-kit mutations in core binding factor leukemias. Blood. 2000;95:726-7.
-
(2000)
Blood
, vol.95
, pp. 726-727
-
-
Beghini, A.1
Peterlongo, P.2
Ripamonti, C.B.3
Larizza, L.4
Cairoli, R.5
Morra, E.6
-
19
-
-
0038170400
-
Incidence and prognosis of c-KIT and FLT3 mutations in core binding factor (CBF) acute myeloid leukaemias
-
Care RS, Valk PJ, Goodeve AC, Abu-Duhier FM, Geertsma-Kleinekoort WM, Wilson GA, et al. Incidence and prognosis of c-KIT and FLT3 mutations in core binding factor (CBF) acute myeloid leukaemias. Br J Haematol. 2003;121:775-7.
-
(2003)
Br J Haematol
, vol.121
, pp. 775-777
-
-
Care, R.S.1
Valk, P.J.2
Goodeve, A.C.3
Abu-Duhier, F.M.4
Geertsma-Kleinekoort, W.M.5
Wilson, G.A.6
-
20
-
-
33646432204
-
Prognostic impact of c-KIT mutations in core binding factor leukemias: An Italian retrospective study
-
Cairoli R, Beghini A, Grillo G, Nadali G, Elice F, Ripamonti CB, et al. Prognostic impact of c-KIT mutations in core binding factor leukemias: An Italian retrospective study. Blood. 2006;107: 3463-8.
-
(2006)
Blood
, vol.107
, pp. 3463-3468
-
-
Cairoli, R.1
Beghini, A.2
Grillo, G.3
Nadali, G.4
Elice, F.5
Ripamonti, C.B.6
-
21
-
-
0036093475
-
FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model
-
Kelly LM, Liu Q, Kutok JL, Williams IR, Boulton CL, Gilliland DG. FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model. Blood. 2002;99:310-8.
-
(2002)
Blood
, vol.99
, pp. 310-318
-
-
Kelly, L.M.1
Liu, Q.2
Kutok, J.L.3
Williams, I.R.4
Boulton, C.L.5
Gilliland, D.G.6
-
22
-
-
0033043084
-
Molecular evolution of acute myeloid leukaemia in relapse: Unstable N-ras and FLT3 genes compared with p53 gene
-
Nakano Y, Kiyoi H, Miyawaki S, Asou N, Ohno R, Saito H, et al. Molecular evolution of acute myeloid leukaemia in relapse: unstable N-ras and FLT3 genes compared with p53 gene. Br J Haematol. 1999;104:659-64.
-
(1999)
Br J Haematol
, vol.104
, pp. 659-664
-
-
Nakano, Y.1
Kiyoi, H.2
Miyawaki, S.3
Asou, N.4
Ohno, R.5
Saito, H.6
-
23
-
-
77957810002
-
High-frequency type I/II mutational shifts between diagnosis and relapse are associated with outcome in pediatric AML: Implications for personalized medicine
-
Bachas C, Schuurhuis GJ, Hollink IH, Kwidama ZJ, Goemans BF, Zwaan CM, et al. High-frequency type I/II mutational shifts between diagnosis and relapse are associated with outcome in pediatric AML: implications for personalized medicine. Blood. 2010;116:2752-8.
-
(2010)
Blood
, vol.116
, pp. 2752-2758
-
-
Bachas, C.1
Schuurhuis, G.J.2
Hollink, I.H.3
Kwidama, Z.J.4
Goemans, B.F.5
Zwaan, C.M.6
-
24
-
-
33745198953
-
Stability and prognostic influence of FLT3 mutations in paired initial and relapsed AML samples
-
Cloos J, Goemans BF, Hess CJ, van Oostveen JW, Waisfisz Q, Corthals S, et al. Stability and prognostic influence of FLT3 mutations in paired initial and relapsed AML samples. Leukemia. 2006;20:1217-20.
-
(2006)
Leukemia
, vol.20
, pp. 1217-1220
-
-
Cloos, J.1
Goemans, B.F.2
Hess, C.J.3
Van, O.J.W.4
Waisfisz, Q.5
Corthals, S.6
-
25
-
-
53249123632
-
-
4th ed., Lyon: WHO Press
-
Swerdlow S, Campo E, Harris N, Jaffe E, Pileri S, Stein H, et al. WHO classification of tumours of haematopoietic and lymphoid tissues. 4th ed. Lyon: WHO Press; 2008.
-
(2008)
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues
-
-
Swerdlow, S.1
Campo, E.2
Harris, N.3
Jaffe, E.4
Pileri, S.5
Stein, H.6
-
26
-
-
19944427850
-
Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype
-
Falini B, Mecucci C, Tiacci E, Alcalay M, Rosati R, Pasqualucci L, et al. Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype. N Engl J Med. 2005;352:254-66.
-
(2005)
N Engl J Med
, vol.352
, pp. 254-266
-
-
Falini, B.1
Mecucci, C.2
Tiacci, E.3
Alcalay, M.4
Rosati, R.5
Pasqualucci, L.6
-
27
-
-
24144494881
-
Clinical characteristics and prognostic implications of NPM1 mutations in acute myeloid leukemia
-
Suzuki T, Kiyoi H, Ozeki K, Tomita A, Yamaji S, Suzuki R, et al. Clinical characteristics and prognostic implications of NPM1 mutations in acute myeloid leukemia. Blood. 2005;106:2854-61.
-
(2005)
Blood
, vol.106
, pp. 2854-2861
-
-
Suzuki, T.1
Kiyoi, H.2
Ozeki, K.3
Tomita, A.4
Yamaji, S.5
Suzuki, R.6
-
28
-
-
0141465061
-
The role of FLT3 in haematopoietic malignancies
-
Stirewalt DL, Radich JP. The role of FLT3 in haematopoietic malignancies. Nat Rev Cancer. 2003;3:650-65.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 650-665
-
-
Stirewalt, D.L.1
Radich, J.P.2
-
29
-
-
33744455709
-
Biology, clinical relevance, and molecularly targeted therapy in acute leukemia with FLT3 mutation
-
Kiyoi H, Naoe T. Biology, clinical relevance, and molecularly targeted therapy in acute leukemia with FLT3 mutation. Int J Hematol. 2006;83:301-8.
-
(2006)
Int J Hematol
, vol.83
, pp. 301-308
-
-
Kiyoi, H.1
Naoe, T.2
-
30
-
-
0036020954
-
FLT3 in human hematologic malignancies
-
Kiyoi H, Naoe T. FLT3 in human hematologic malignancies. Leuk Lymphoma. 2002;43:1541-7.
-
(2002)
Leuk Lymphoma
, vol.43
, pp. 1541-1547
-
-
Kiyoi, H.1
Naoe, T.2
-
31
-
-
66249137734
-
Mutation in TET2 in myeloid cancers
-
Delhommeau F, Dupont S, Della Valle V, James C, Trannoy S, Masse A, et al. Mutation in TET2 in myeloid cancers. N Engl J Med. 2009;360:2289-301.
-
(2009)
N Engl J Med
, vol.360
, pp. 2289-2301
-
-
Delhommeau, F.1
Dupont, S.2
Della, V.V.3
James, C.4
Trannoy, S.5
Masse, A.6
-
32
-
-
67649876132
-
Acquired mutations in TET2 are common in myelodysplastic syndromes
-
Langemeijer SM, Kuiper RP, Berends M, Knops R, Aslanyan MG, Massop M, et al. Acquired mutations in TET2 are common in myelodysplastic syndromes. Nat Genet. 2009;41:838-42.
-
(2009)
Nat Genet
, vol.41
, pp. 838-842
-
-
Langemeijer, S.M.1
Kuiper, R.P.2
Berends, M.3
Knops, R.4
Aslanyan, M.G.5
Massop, M.6
-
33
-
-
70149093912
-
Recurring mutations found by sequencing an acute myeloid leukemia genome
-
Mardis ER, Ding L, Dooling DJ, Larson DE, McLellan MD, Chen K, et al. Recurring mutations found by sequencing an acute myeloid leukemia genome. N Engl J Med. 2009;361:1058-66.
-
(2009)
N Engl J Med
, vol.361
, pp. 1058-1066
-
-
Mardis, E.R.1
Ding, L.2
Dooling, D.J.3
Larson, D.E.4
McLellan, M.D.5
Chen, K.6
-
34
-
-
78649906060
-
DNMT3A mutations in acute myeloid leukemia
-
Ley TJ, Ding L, Walter MJ, McLellan MD, Lamprecht T, Larson DE, et al. DNMT3A mutations in acute myeloid leukemia. N Engl J Med. 2010;363:2424-33.
-
(2010)
N Engl J Med
, vol.363
, pp. 2424-2433
-
-
Ley, T.J.1
Ding, L.2
Walter, M.J.3
McLellan, M.D.4
Lamprecht, T.5
Larson, D.E.6
-
35
-
-
77955087290
-
Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes
-
Nikoloski G, Langemeijer SM, Kuiper RP, Knops R, Massop M, Tonnissen ER, et al. Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes. Nat Genet. 2010;42:665-7.
-
(2010)
Nat Genet
, vol.42
, pp. 665-667
-
-
Nikoloski, G.1
Langemeijer, S.M.2
Kuiper, R.P.3
Knops, R.4
Massop, M.5
Tonnissen, E.R.6
-
36
-
-
84866378702
-
The role of mutations in epigenetic regulators in myeloid malignancies
-
Shih AH, Abdel-Wahab O, Patel JP, Levine RL. The role of mutations in epigenetic regulators in myeloid malignancies. Nat Rev Cancer. 2012;12:599-612.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 599-612
-
-
Shih, A.H.1
Abdel-Wahab, O.2
Patel, J.P.3
Levine, R.L.4
-
37
-
-
78549279199
-
Distinct clinical and biological features of de novo acute myeloid leukemia with additional sex comb-like 1 (ASXL1) mutations
-
Chou WC, Huang HH, Hou HA, Chen CY, Tang JL, Yao M, et al. Distinct clinical and biological features of de novo acute myeloid leukemia with additional sex comb-like 1 (ASXL1) mutations. Blood. 2010;116:4086-94.
-
(2010)
Blood
, vol.116
, pp. 4086-4094
-
-
Chou, W.C.1
Huang, H.H.2
Hou, H.A.3
Chen, C.Y.4
Tang, J.L.5
Yao, M.6
-
38
-
-
83055161507
-
Whole-exome sequencing identifies somatic mutations of BCOR in acute myeloid leukemia with normal karyotype
-
Grossmann V, Tiacci E, Holmes AB, Kohlmann A, Martelli MP, Kern W, et al. Whole-exome sequencing identifies somatic mutations of BCOR in acute myeloid leukemia with normal karyotype. Blood. 2011;118:6153-63.
-
(2011)
Blood
, vol.118
, pp. 6153-6163
-
-
Grossmann, V.1
Tiacci, E.2
Holmes, A.B.3
Kohlmann, A.4
Martelli, M.P.5
Kern, W.6
-
39
-
-
82155183257
-
Somatic mutations in the transcriptional corepressor gene BCORL1 in adult acute myelogenous leukemia
-
Li M, Collins R, Jiao Y, Ouillette P, Bixby D, Erba H, et al. Somatic mutations in the transcriptional corepressor gene BCORL1 in adult acute myelogenous leukemia. Blood. 2011; 118:5914-7.
-
(2011)
Blood
, vol.118
, pp. 5914-5917
-
-
Li, M.1
Collins, R.2
Jiao, Y.3
Ouillette, P.4
Bixby, D.5
Erba, H.6
-
40
-
-
84864255882
-
The origin and evolution of mutations in acute myeloid leukemia
-
Welch JS, Ley TJ, Link DC, Miller CA, Larson DE, Koboldt DC, et al. The origin and evolution of mutations in acute myeloid leukemia. Cell. 2012;150:264-78.
-
(2012)
Cell
, vol.150
, pp. 264-278
-
-
Welch, J.S.1
Ley, T.J.2
Link, D.C.3
Miller, C.A.4
Larson, D.E.5
Koboldt, D.C.6
-
41
-
-
84868148842
-
Splicing factor mutations in myelodysplasia
-
Ogawa S. Splicing factor mutations in myelodysplasia. Int J Hematol. 2012;96:438-42.
-
(2012)
Int J Hematol
, vol.96
, pp. 438-442
-
-
Ogawa, S.1
-
42
-
-
84868091622
-
SF3B1 haploinsufficiency leads to formation of ring sideroblasts in myelodysplastic syndromes
-
Visconte V, Rogers HJ, Singh J, Barnard J, Bupathi M, Traina F, et al. SF3B1 haploinsufficiency leads to formation of ring sideroblasts in myelodysplastic syndromes. Blood. 2012;120: 3173-86.
-
(2012)
Blood
, vol.120
, pp. 3173-3186
-
-
Visconte, V.1
Rogers, H.J.2
Singh, J.3
Barnard, J.4
Bupathi, M.5
Traina, F.6
-
43
-
-
79955538247
-
Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain
-
Guo JU, Su Y, Zhong C, Ming GL, Song H. Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain. Cell. 2011;145:423-34.
-
(2011)
Cell
, vol.145
, pp. 423-434
-
-
Guo, J.U.1
Su, Y.2
Zhong, C.3
Ming, G.L.4
Song, H.5
-
44
-
-
66149146320
-
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
-
Tahiliani M, Koh KP, Shen Y, Pastor WA, Bandukwala H, Brudno Y, et al. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science. 2009;324:930-5.
-
(2009)
Science
, vol.324
, pp. 930-935
-
-
Tahiliani, M.1
Koh, K.P.2
Shen, Y.3
Pastor, W.A.4
Bandukwala, H.5
Brudno, Y.6
-
45
-
-
78650175023
-
Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2
-
Ko M, Huang Y, Jankowska AM, Pape UJ, Tahiliani M, Bandukwala HS, et al. Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2. Nature. 2010;468:839-43.
-
(2010)
Nature
, vol.468
, pp. 839-843
-
-
Ko, M.1
Huang, Y.2
Jankowska, A.M.3
Pape, U.J.4
Tahiliani, M.5
Bandukwala, H.S.6
-
46
-
-
67651065502
-
Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies
-
Abdel-Wahab O, Mullally A, Hedvat C, Garcia-Manero G, Patel J, Wadleigh M, et al. Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies. Blood. 2009;114: 144-7.
-
(2009)
Blood
, vol.114
, pp. 144-147
-
-
Abdel-Wahab, O.1
Mullally, A.2
Hedvat, C.3
Garcia-Manero, G.4
Patel, J.5
Wadleigh, M.6
-
47
-
-
79954428737
-
TET2 mutations improve the new European Leukemia Net risk classification of acute myeloid leukemia: A Cancer and Leukemia Group B study
-
Metzeler KH, Maharry K, Radmacher MD, Mrozek K, Margeson D, Becker H, et al. TET2 mutations improve the new European Leukemia Net risk classification of acute myeloid leukemia: A Cancer and Leukemia Group B study. J Clin Oncol. 2011;29: 1373-81.
-
(2011)
J Clin Oncol
, vol.29
, pp. 1373-1381
-
-
Metzeler, K.H.1
Maharry, K.2
Radmacher, M.D.3
Mrozek, K.4
Margeson, D.5
Becker, H.6
-
48
-
-
84862266735
-
TET2 mutations in acute myeloid leukemia (AML): Results from a comprehensive genetic and clinical analysis of the AML study group
-
Gaidzik VI, Paschka P, Spath D, Habdank M, Kohne CH, Germing U, et al. TET2 mutations in acute myeloid leukemia (AML): results from a comprehensive genetic and clinical analysis of the AML study group. J Clin Oncol. 2012;30:1350-7.
-
(2012)
J Clin Oncol
, vol.30
, pp. 1350-1357
-
-
Gaidzik, V.I.1
Paschka, P.2
Spath, D.3
Habdank, M.4
Kohne, C.H.5
Germing, U.6
-
49
-
-
80053620171
-
TET2 mutation is an unfavorable prognostic factor in acute myeloid leukemia patients with intermediate-risk cytogenetics
-
Chou WC, Chou SC, Liu CY, Chen CY, Hou HA, Kuo YY, et al. TET2 mutation is an unfavorable prognostic factor in acute myeloid leukemia patients with intermediate-risk cytogenetics. Blood. 2011;118:3803-10.
-
(2011)
Blood
, vol.118
, pp. 3803-3810
-
-
Chou, W.C.1
Chou, S.C.2
Liu, C.Y.3
Chen, C.Y.4
Hou, H.A.5
Kuo, Y.Y.6
-
50
-
-
84863393263
-
Prognostic relevance of integrated genetic profiling in acute myeloid leukemia
-
Patel JP, Gonen M, Figueroa ME, Fernandez H, Sun Z, Racevskis J, et al. Prognostic relevance of integrated genetic profiling in acute myeloid leukemia. N Engl J Med. 2012;366:1079-89.
-
(2012)
N Engl J Med
, vol.366
, pp. 1079-1089
-
-
Patel, J.P.1
Gonen, M.2
Figueroa, M.E.3
Fernandez, H.4
Sun, Z.5
Racevskis, J.6
-
51
-
-
80052495940
-
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA
-
He YF, Li BZ, Li Z, Liu P, Wang Y, Tang Q, et al. Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. Science. 2011;333:1303-7.
-
(2011)
Science
, vol.333
, pp. 1303-1307
-
-
He, Y.F.1
Li, B.Z.2
Li, Z.3
Liu, P.4
Wang, Y.5
Tang, Q.6
-
52
-
-
79954457998
-
Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells
-
Wu H, D'Alessio AC, Ito S, Wang Z, Cui K, Zhao K, et al. Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells. Genes Dev. 2011;25:679-84.
-
(2011)
Genes Dev
, vol.25
, pp. 679-684
-
-
Wu, H.1
D'Alessio, A.C.2
Ito, S.3
Wang, Z.4
Cui, K.5
Zhao, K.6
-
53
-
-
79956323623
-
Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation
-
Ficz G, Branco MR, Seisenberger S, Santos F, Krueger F, Hore TA, et al. Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation. Nature. 2011;473: 398-402.
-
(2011)
Nature
, vol.473
, pp. 398-402
-
-
Ficz, G.1
Branco, M.R.2
Seisenberger, S.3
Santos, F.4
Krueger, F.5
Hore, T.A.6
-
54
-
-
79960064353
-
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation
-
Moran-Crusio K, Reavie L, Shih A, Abdel-Wahab O, Ndiaye- Lobry D, Lobry C, et al. Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation. Cancer Cell. 2011;20:11-24.
-
(2011)
Cancer Cell
, vol.20
, pp. 11-24
-
-
Moran-Crusio, K.1
Reavie, L.2
Shih, A.3
Abdel-Wahab, O.4
Ndiaye-Lobry, D.5
Lobry, C.6
-
55
-
-
79955059411
-
The DNMT3 family of mammalian de novo DNA methyltransferases
-
Chedin F. The DNMT3 family of mammalian de novo DNA methyltransferases. Prog Mol Biol Transl Sci. 2011;101:255-85.
-
(2011)
Prog Mol Biol Transl Sci
, vol.101
, pp. 255-285
-
-
Chedin, F.1
-
56
-
-
79960735923
-
Incidence and prognostic influence of DNMT3A mutations in acute myeloid leukemia
-
Thol F, Damm F, Ludeking A, Winschel C, Wagner K, Morgan M, et al. Incidence and prognostic influence of DNMT3A mutations in acute myeloid leukemia. J Clin Oncol. 2011;29:2889-96.
-
(2011)
J Clin Oncol
, vol.29
, pp. 2889-2896
-
-
Thol, F.1
Damm, F.2
Ludeking, A.3
Winschel, C.4
Wagner, K.5
Morgan, M.6
-
57
-
-
79953176952
-
Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia
-
Yan XJ, Xu J, Gu ZH, Pan CM, Lu G, Shen Y, et al. Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia. Nat Genet. 2011;43:309-15.
-
(2011)
Nat Genet
, vol.43
, pp. 309-315
-
-
Yan, X.J.1
Xu, J.2
Gu, Z.H.3
Pan, C.M.4
Lu, G.5
Shen, Y.6
-
58
-
-
84856477048
-
Frequency, onset and clinical impact of somatic DNMT3A mutations in therapy-related and secondary acute myeloid leukemia
-
Fried I, Bodner C, Pichler MM, Lind K, Beham-Schmid C, Quehenberger F, et al. Frequency, onset and clinical impact of somatic DNMT3A mutations in therapy-related and secondary acute myeloid leukemia. Haematologica. 2012;97:246-50.
-
(2012)
Haematologica
, vol.97
, pp. 246-250
-
-
Fried, I.1
Bodner, C.2
Pichler, M.M.3
Lind, K.4
Beham-Schmid, C.5
Quehenberger, F.6
-
59
-
-
34547725157
-
DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA
-
Ooi SK, Qiu C, Bernstein E, Li K, Jia D, Yang Z, et al. DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA. Nature. 2007;448:714-7.
-
(2007)
Nature
, vol.448
, pp. 714-717
-
-
Ooi, S.K.1
Qiu, C.2
Bernstein, E.3
Li, K.4
Jia, D.5
Yang, Z.6
-
60
-
-
34247337999
-
De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells
-
Tadokoro Y, Ema H, Okano M, Li E, Nakauchi H. De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells. J Exp Med. 2007;204:715-22.
-
(2007)
J Exp Med
, vol.204
, pp. 715-722
-
-
Tadokoro, Y.1
Ema, H.2
Okano, M.3
Li, E.4
Nakauchi, H.5
-
61
-
-
84555207349
-
DNMT3A is essential for hematopoietic stem cell differentiation
-
Challen GA, Sun D, Jeong M, Luo M, Jelinek J, Berg JS, et al. DNMT3A is essential for hematopoietic stem cell differentiation. Nat Genet. 2012;44:23-31.
-
(2012)
Nat Genet
, vol.44
, pp. 23-31
-
-
Challen, G.A.1
Sun, D.2
Jeong, M.3
Luo, M.4
Jelinek, J.5
Berg, J.S.6
-
62
-
-
78751662908
-
The Polycomb complex PRC2 and its mark in life
-
Margueron R, Reinberg D. The Polycomb complex PRC2 and its mark in life. Nature. 2011;469:343-9.
-
(2011)
Nature
, vol.469
, pp. 343-349
-
-
Margueron, R.1
Reinberg, D.2
-
63
-
-
0033569427
-
Functional antagonism of the Polycomb- Group genes eed and Bmi1 in hemopoietic cell proliferation
-
Lessard J, Schumacher A, Thorsteinsdottir U, van Lohuizen M, Magnuson T, Sauvageau G. Functional antagonism of the Polycomb- Group genes eed and Bmi1 in hemopoietic cell proliferation. Genes Dev. 1999;13:2691-703.
-
(1999)
Genes Dev
, vol.13
, pp. 2691-2703
-
-
Lessard, J.1
Schumacher, A.2
Thorsteinsdottir, U.3
Van, L.M.4
Magnuson, T.5
Sauvageau, G.6
-
64
-
-
18644382388
-
The polycomb group protein EZH2 is involved in progression of prostate cancer
-
Varambally S, Dhanasekaran SM, Zhou M, Barrette TR, Kumar- Sinha C, Sanda MG, et al. The polycomb group protein EZH2 is involved in progression of prostate cancer. Nature. 2002;419: 624-9.
-
(2002)
Nature
, vol.419
, pp. 624-629
-
-
Varambally, S.1
Dhanasekaran, S.M.2
Zhou, M.3
Barrette, T.R.4
Kumar-Sinha, C.5
Sanda, M.G.6
-
65
-
-
75749124332
-
Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin
-
Morin RD, Johnson NA, Severson TM, Mungall AJ, An J, Goya R, et al. Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin. Nat Genet. 2010;42:181-5.
-
(2010)
Nat Genet
, vol.42
, pp. 181-185
-
-
Morin, R.D.1
Johnson, N.A.2
Severson, T.M.3
Mungall, A.J.4
An, J.5
Goya, R.6
-
66
-
-
84864567410
-
Ezh2 augments leukemogenicity by reinforcing differentiation blockage in acute myeloid leukemia
-
Tanaka S, Miyagi S, Sashida G, Chiba T, Yuan J, Mochizuki- Kashio M, et al. Ezh2 augments leukemogenicity by reinforcing differentiation blockage in acute myeloid leukemia. Blood. 2012;120:1107-17.
-
(2012)
Blood
, vol.120
, pp. 1107-1117
-
-
Tanaka, S.1
Miyagi, S.2
Sashida, G.3
Chiba, T.4
Yuan, J.5
Mochizuki-Kashio, M.6
-
67
-
-
77955085750
-
Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders
-
Ernst T, Chase AJ, Score J, Hidalgo-Curtis CE, Bryant C, Jones AV, et al. Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders. Nat Genet. 2010;42:722-6.
-
(2010)
Nat Genet
, vol.42
, pp. 722-726
-
-
Ernst, T.1
Chase, A.J.2
Score, J.3
Hidalgo-Curtis, C.E.4
Bryant, C.5
Jones, A.V.6
-
68
-
-
79960227474
-
Concomitant analysis of EZH2 and ASXL1 mutations in myelofibrosis, chronic myelomonocytic leukemia and blast-phase myeloproliferative neoplasms
-
Abdel-Wahab O, Pardanani A, Patel J, Wadleigh M, Lasho T, Heguy A, et al. Concomitant analysis of EZH2 and ASXL1 mutations in myelofibrosis, chronic myelomonocytic leukemia and blast-phase myeloproliferative neoplasms. Leukemia. 2011; 25:1200-2.
-
(2011)
Leukemia
, vol.25
, pp. 1200-1202
-
-
Abdel-Wahab, O.1
Pardanani, A.2
Patel, J.3
Wadleigh, M.4
Lasho, T.5
Heguy, A.6
-
69
-
-
0037320925
-
Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement
-
Su IH, Basavaraj A, Krutchinsky AN, Hobert O, Ullrich A, Chait BT, et al. Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement. Nat Immunol. 2003;4:124-31.
-
(2003)
Nat Immunol
, vol.4
, pp. 124-131
-
-
Su, I.H.1
Basavaraj, A.2
Krutchinsky, A.N.3
Hobert, O.4
Ullrich, A.5
Chait, B.T.6
-
70
-
-
77956265489
-
IDH mutations in glioma and acute myeloid leukemia
-
Dang L, Jin S, Su SM. IDH mutations in glioma and acute myeloid leukemia. Trends Mol Med. 2010;16:387-97.
-
(2010)
Trends Mol Med
, vol.16
, pp. 387-397
-
-
Dang, L.1
Jin, S.2
Su, S.M.3
-
71
-
-
77952536841
-
IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia: A Cancer and Leukemia Group B study
-
Marcucci G, Maharry K, Wu YZ, Radmacher MD, Mrozek K, Margeson D, et al. IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia: A Cancer and Leukemia Group B study. J Clin Oncol. 2010;28:2348-55.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2348-2355
-
-
Marcucci, G.1
Maharry, K.2
Wu, Y.Z.3
Radmacher, M.D.4
Mrozek, K.5
Margeson, D.6
-
72
-
-
77955907891
-
IDH1 and IDH2 mutations are frequent genetic alterations in acute myeloid leukemia and confer adverse prognosis in cytogenetically normal acute myeloid leukemia with NPM1 mutation without FLT3 internal tandem duplication
-
Paschka P, Schlenk RF, Gaidzik VI, Habdank M, Kronke J, Bullinger L, et al. IDH1 and IDH2 mutations are frequent genetic alterations in acute myeloid leukemia and confer adverse prognosis in cytogenetically normal acute myeloid leukemia with NPM1 mutation without FLT3 internal tandem duplication. J Clin Oncol. 2010;28:3636-43.
-
(2010)
J Clin Oncol
, vol.28
, pp. 3636-3643
-
-
Paschka, P.1
Schlenk, R.F.2
Gaidzik, V.I.3
Habdank, M.4
Kronke, J.5
Bullinger, L.6
-
73
-
-
77956050251
-
Prognostic impact of IDH2 mutations in cytogenetically normal acute myeloid leukemia
-
Thol F, Damm F, Wagner K, Gohring G, Schlegelberger B, Hoelzer D, et al. Prognostic impact of IDH2 mutations in cytogenetically normal acute myeloid leukemia. Blood. 2010;116: 614-6.
-
(2010)
Blood
, vol.116
, pp. 614-616
-
-
Thol, F.1
Damm, F.2
Wagner, K.3
Gohring, G.4
Schlegelberger, B.5
Hoelzer, D.6
-
74
-
-
77952481300
-
Impact of IDH1 R132 mutations and an IDH1 single nucleotide polymorphism in cytogenetically normal acute myeloid leukemia: SNP rs11554137 is an adverse prognostic factor
-
Wagner K, Damm F, Gohring G, Gorlich K, Heuser M, Schafer I, et al. Impact of IDH1 R132 mutations and an IDH1 single nucleotide polymorphism in cytogenetically normal acute myeloid leukemia: SNP rs11554137 is an adverse prognostic factor. J Clin Oncol. 2010;28:2356-64.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2356-2364
-
-
Wagner, K.1
Damm, F.2
Gohring, G.3
Gorlich, K.4
Heuser, M.5
Schafer, I.6
-
75
-
-
77649305610
-
The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate
-
Ward PS, Patel J, Wise DR, Abdel-Wahab O, Bennett BD, Coller HA, et al. The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate. Cancer Cell. 2010;17: 225-34.
-
(2010)
Cancer Cell
, vol.17
, pp. 225-234
-
-
Ward, P.S.1
Patel, J.2
Wise, D.R.3
Abdel-Wahab, O.4
Bennett, B.D.5
Coller, H.A.6
-
76
-
-
72049125350
-
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
-
Dang L, White DW, Gross S, Bennett BD, Bittinger MA, Driggers EM, et al. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature. 2009;462:739-44.
-
(2009)
Nature
, vol.462
, pp. 739-744
-
-
Dang, L.1
White, D.W.2
Gross, S.3
Bennett, B.D.4
Bittinger, M.A.5
Driggers, E.M.6
-
77
-
-
64849098267
-
Gliomaderived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha
-
Zhao S, Lin Y, Xu W, Jiang W, Zha Z, Wang P, et al. Gliomaderived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha. Science. 2009;324:261-5.
-
(2009)
Science
, vol.324
, pp. 261-265
-
-
Zhao, S.1
Lin, Y.2
Xu, W.3
Jiang, W.4
Zha, Z.5
Wang, P.6
-
79
-
-
80053963323
-
CTCF, cohesin, and histone variants: Connecting the genome
-
Millau JF, Gaudreau L. CTCF, cohesin, and histone variants: connecting the genome. Biochem Cell Biol. 2011;89:505-13.
-
(2011)
Biochem Cell Biol
, vol.89
, pp. 505-513
-
-
Millau, J.F.1
Gaudreau, L.2
-
80
-
-
84868554484
-
Commonly altered genomic regions in acute myeloid leukemia are enriched for somatic mutations involved in chromatin-remodeling and splicing
-
Dolnik A, Engelmann JC, Scharfenberger-Schmeer M, Mauch J, Kelkenberg-Schade S, Haldemann B, et al. Commonly altered genomic regions in acute myeloid leukemia are enriched for somatic mutations involved in chromatin-remodeling and splicing. Blood. 2012;120:e83-e92.
-
(2012)
Blood
, vol.120
-
-
Dolnik, A.1
Engelmann, J.C.2
Scharfenberger-Schmeer, M.3
Mauch, J.4
Kelkenberg-Schade, S.5
Haldemann, B.6
-
81
-
-
84863337617
-
Clonal architecture of secondary acute myeloid leukemia
-
Walter MJ, Shen D, Ding L, Shao J, Koboldt DC, Chen K, et al. Clonal architecture of secondary acute myeloid leukemia. N Engl J Med. 2012;366:1090-8.
-
(2012)
N Engl J Med
, vol.366
, pp. 1090-1098
-
-
Walter, M.J.1
Shen, D.2
Ding, L.3
Shao, J.4
Koboldt, D.C.5
Chen, K.6
-
82
-
-
34447538496
-
A novel corepressor, BCoR-L1, represses transcription through an interaction with CtBP
-
Pagan JK, Arnold J, Hanchard KJ, Kumar R, Bruno T, Jones MJ, et al. A novel corepressor, BCoR-L1, represses transcription through an interaction with CtBP. J Biol Chem. 2007;282: 15248-57.
-
(2007)
J Biol Chem
, vol.282
, pp. 15248-15257
-
-
Pagan, J.K.1
Arnold, J.2
Hanchard, K.J.3
Kumar, R.4
Bruno, T.5
Jones, M.J.6
-
83
-
-
74949143986
-
Loss-of-function Additional sex combs like 1 mutations disrupt hematopoiesis but do not cause severe myelodysplasia or leukemia
-
Fisher CL, Pineault N, Brookes C, Helgason CD, Ohta H, Bodner C, et al. Loss-of-function Additional sex combs like 1 mutations disrupt hematopoiesis but do not cause severe myelodysplasia or leukemia. Blood. 2010;115:38-46.
-
(2010)
Blood
, vol.115
, pp. 38-46
-
-
Fisher, C.L.1
Pineault, N.2
Brookes, C.3
Helgason, C.D.4
Ohta, H.5
Bodner, C.6
-
84
-
-
0031946630
-
The Additional sex combs gene of drosophila encodes a chromatin protein that binds to shared and unique Polycomb group sites on polytene chromosomes
-
Sinclair DA, Milne TA, Hodgson JW, Shellard J, Salinas CA, Kyba M, et al. The Additional sex combs gene of Drosophila encodes a chromatin protein that binds to shared and unique Polycomb group sites on polytene chromosomes. Development. 1998;125:1207-16.
-
(1998)
Development
, vol.125
, pp. 1207-1216
-
-
Sinclair, D.A.1
Milne, T.A.2
Hodgson, J.W.3
Shellard, J.4
Salinas, C.A.5
Kyba, M.6
-
85
-
-
84865152223
-
ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression
-
Abdel-Wahab O, Adli M, Lafave LM, Gao J, Hricik T, Shih AH, et al. ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression. Cancer Cell. 2012;22: 180-93.
-
(2012)
Cancer Cell
, vol.22
, pp. 180-193
-
-
Abdel-Wahab, O.1
Adli, M.2
Lafave, L.M.3
Gao, J.4
Hricik, T.5
Shih, A.H.6
-
86
-
-
79959794787
-
Clinical effect of point mutations in myelodysplastic syndromes
-
Bejar R, Stevenson K, Abdel-Wahab O, Galili N, Nilsson B, Garcia-Manero G, et al. Clinical effect of point mutations in myelodysplastic syndromes. N Engl J Med. 2011;364:2496-506.
-
(2011)
N Engl J Med
, vol.364
, pp. 2496-2506
-
-
Bejar, R.1
Stevenson, K.2
Abdel-Wahab, O.3
Galili, N.4
Nilsson, B.5
Garcia-Manero, G.6
-
87
-
-
84255176496
-
ASXL1 mutations identify a high-risk subgroup of older patients with primary cytogenetically normal AML within the ELN favorable genetic category
-
Metzeler KH, Becker H, Maharry K, Radmacher MD, Kohlschmidt J, Mrozek K, et al. ASXL1 mutations identify a high-risk subgroup of older patients with primary cytogenetically normal AML within the ELN favorable genetic category. Blood. 2011; 118:6920-9.
-
(2011)
Blood
, vol.118
, pp. 6920-6929
-
-
Metzeler, K.H.1
Becker, H.2
Maharry, K.3
Radmacher, M.D.4
Kohlschmidt, J.5
Mrozek, K.6
-
88
-
-
84867806184
-
A novel hierarchical prognostic model of AML solely based on molecular mutations
-
Grossmann V, Schnittger S, Kohlmann A, Eder C, Roller A, Dicker F, et al. A novel hierarchical prognostic model of AML solely based on molecular mutations. Blood. 2012;120:2963-72.
-
(2012)
Blood
, vol.120
, pp. 2963-2972
-
-
Grossmann, V.1
Schnittger, S.2
Kohlmann, A.3
Eder, C.4
Roller, A.5
Dicker, F.6
-
89
-
-
80053629571
-
Disruption of the ASXL1 gene is frequent in primary, post-essential thrombocytosis and post-polycythemia vera myelofibrosis, but not essential thrombocytosis or polycythemia vera: Analysis of molecular genetics and clinical phenotypes
-
Stein BL, Williams DM, O'Keefe C, Rogers O, Ingersoll RG, Spivak JL, et al. Disruption of the ASXL1 gene is frequent in primary, post-essential thrombocytosis and post-polycythemia vera myelofibrosis, but not essential thrombocytosis or polycythemia vera: Analysis of molecular genetics and clinical phenotypes. Haematologica. 2011;96:1462-9.
-
(2011)
Haematologica
, vol.96
, pp. 1462-1469
-
-
Stein, B.L.1
Williams, D.M.2
O'Keefe, C.3
Rogers, O.4
Ingersoll, R.G.5
Spivak, J.L.6
-
90
-
-
84859595800
-
Mutations affecting mRNA splicing define distinct clinical phenotypes and correlate with patient outcome in myelodysplastic syndromes
-
Damm F, Kosmider O, Gelsi-Boyer V, Renneville A, Carbuccia N, Hidalgo-Curtis C, et al. Mutations affecting mRNA splicing define distinct clinical phenotypes and correlate with patient outcome in myelodysplastic syndromes. Blood. 2012;119:3211-8.
-
(2012)
Blood
, vol.119
, pp. 3211-3218
-
-
Damm, F.1
Kosmider, O.2
Gelsi-Boyer, V.3
Renneville, A.4
Carbuccia, N.5
Hidalgo-Curtis, C.6
-
91
-
-
84858600403
-
Mutations in ASXL1 are associated with poor prognosis across the spectrum of malignant myeloid diseases
-
Gelsi-Boyer V, Brecqueville M, Devillier R, Murati A, Mozziconacci MJ, Birnbaum D. Mutations in ASXL1 are associated with poor prognosis across the spectrum of malignant myeloid diseases. J Hematol Oncol. 2012;5:12.
-
(2012)
J Hematol Oncol
, vol.5
, pp. 12
-
-
Gelsi-Boyer, V.1
Brecqueville, M.2
Devillier, R.3
Murati, A.4
Mozziconacci, M.J.5
Birnbaum, D.6
-
92
-
-
84862012956
-
The role of minor subpopulations within the leukemic blast compartment of AML patients at initial diagnosis in the development of relapse
-
Bachas C, Schuurhuis GJ, Assaraf YG, Kwidama ZJ, Kelder A, Wouters F, et al. The role of minor subpopulations within the leukemic blast compartment of AML patients at initial diagnosis in the development of relapse. Leukemia. 2012;26:1313-20.
-
(2012)
Leukemia
, vol.26
, pp. 1313-1320
-
-
Bachas, C.1
Schuurhuis, G.J.2
Assaraf, Y.G.3
Kwidama, Z.J.4
Kelder, A.5
Wouters, F.6
-
93
-
-
84862776906
-
Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing
-
Ding L, Ley TJ, Larson DE, Miller CA, Koboldt DC, Welch JS, et al. Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing. Nature. 2012;481:506-10.
-
(2012)
Nature
, vol.481
, pp. 506-510
-
-
Ding, L.1
Ley, T.J.2
Larson, D.E.3
Miller, C.A.4
Koboldt, D.C.5
Welch, J.S.6
-
94
-
-
77955914238
-
Refinement of cytogenetic classification in acute myeloid leukemia: Determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom medical research council trials
-
Grimwade D, Hills RK, Moorman AV, Walker H, Chatters S, Goldstone AH, et al. Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials. Blood. 2010;116:354-65.
-
(2010)
Blood
, vol.116
, pp. 354-365
-
-
Grimwade, D.1
Hills, R.K.2
Moorman, A.V.3
Walker, H.4
Chatters, S.5
Goldstone, A.H.6
-
95
-
-
77449159028
-
Diagnosis and management of acute myeloid leukemia in adults: Recommendations from an international expert panel, on behalf of the European leukemia net
-
Dohner H, Estey EH, Amadori S, Appelbaum FR, Buchner T, Burnett AK, et al. Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European Leukemia Net. Blood. 2010;115:453-74.
-
(2010)
Blood
, vol.115
, pp. 453-474
-
-
Dohner, H.1
Estey, E.H.2
Amadori, S.3
Appelbaum, F.R.4
Buchner, T.5
Burnett, A.K.6
|