Alpha-lipoic acid induces adipose triglyceride lipase expression and decreases intracellular lipid accumulation in HepG2 cells

European Journal of Pharmacology

Volumn 692, Issue 1-3, 2012, Pages 10-18

  Kuo, Yung Ting ^a,b   Lin, Ting Han ^b   Chen, Wei Lu ^b   Lee, Horng Mo ^b,c  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c CENTRAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

Author keywords

5 AMP activated protein kinase (AMPK); Adipose triglyceride lipase (ATGL); Alpha lipoic acid (ALA); Forkhead box O1 (FOXO1)

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; 5' AMP ACTIVATED PROTEIN KINASE; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; METFORMIN; PALMITIC ACID; PALMITIC ACID DERIVATIVE; THIOCTIC ACID; TRANSCRIPTION FACTOR FKHR; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HEPG2; CONTROLLED STUDY; DRUG EFFICACY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; FATTY LIVER; HUMAN; HUMAN CELL; LIPID HYDROLYSIS; LIPID STORAGE; LIVER CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TREATMENT RESPONSE;

ACTIVE TRANSPORT, CELL NUCLEUS; AMP-ACTIVATED PROTEIN KINASES; CELL NUCLEUS; ENZYME ACTIVATION; FATTY LIVER; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUCOSE; HEP G2 CELLS; HUMANS; INSULIN; INTRACELLULAR SPACE; LIPASE; LIPID METABOLISM; PHOSPHORYLATION; SIGNAL TRANSDUCTION; SIRTUIN 1; THIOCTIC ACID;

EID: 84865865516     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.07.028     Document Type: Article

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