Activity and crystal structure of human thymine DNA glycosylase mutant N140A with 5-carboxylcytosine DNA at low pH

DNA Repair

Volumn 12, Issue 7, 2013, Pages 535-540

  Hashimoto, Hideharu ^a   Zhang, Xing ^a   Cheng, Xiaodong ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

5 Carboxylcytosine; DNA 5mC oxidation; DNA modification; Epigenetic regulation; Thymine DNA glycosylase

Indexed keywords

5 CARBOXYLCYTOSINE; CYTOSINE; THYMINE DNA GLYCOSYLASE; UNCLASSIFIED DRUG;

ARTICLE; CRYSTAL STRUCTURE; DNA CONFORMATION; DNA STRUCTURE; ENZYME ACTIVITY; GENE MUTATION; MOLECULAR INTERACTION; PH; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; CYTOSINE; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; MOLECULAR DOCKING SIMULATION; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; SUBSTRATE SPECIFICITY; THYMINE DNA GLYCOSYLASE;

MAMMALIA;

EID: 84878667424     PISSN: 15687864     EISSN: 15687856     Source Type: Journal    
DOI: 10.1016/j.dnarep.2013.04.003     Document Type: Article

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