Effect of hyperpolarization-activated current If on robustness of sinoatrial node pacemaking: Theoretical study on influence of intracellular Na+ concentration

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 304, Issue 10, 2013, Pages

  Kurata, Yasutaka ^a   Hisatome, Ichiro ^b   Tanida, Mamoru ^a   Shibamoto, Toshishige ^a  

^a KANAZAWA MEDICAL UNIVERSITY   (Japan)

^b TOTTORI UNIVERSITY   (Japan)

Author keywords

Bifurcation analysis; Computer simulation; Hyperpolarizing load; Mathematical model; Nonlinear dynamics

Indexed keywords

CALCIUM CHANNEL L TYPE; POTASSIUM CHANNEL; SODIUM ION;

ARTICLE; CALCIUM CONDUCTANCE; CONCEPTUAL FRAMEWORK; CONTROLLED STUDY; HYPERPOLARIZATION; INHIBITION KINETICS; MATHEMATICAL MODEL; MEMBRANE POTENTIAL; MOLECULAR DYNAMICS; OSCILLATION; POTASSIUM CURRENT; PRIORITY JOURNAL; SINUS NODE; SODIUM CURRENT;

BIFURCATION ANALYSIS; COMPUTER SIMULATION; HYPERPOLARIZING LOAD; MATHEMATICAL MODEL; NONLINEAR DYNAMICS;

ACETYLCHOLINE; ALGORITHMS; ANIMALS; BIOLOGICAL CLOCKS; CALCIUM CHANNELS, L-TYPE; CELLS, CULTURED; CYCLIC NUCLEOTIDE-GATED CATION CHANNELS; ELECTROPHYSIOLOGICAL PHENOMENA; HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNELS; MEMBRANE POTENTIALS; MODELS, STATISTICAL; POTASSIUM CHANNELS; RABBITS; SINOATRIAL NODE; SODIUM;

EID: 84878618238     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00777.2012     Document Type: Article

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