Engineering physiologically controlled pacemaker cells with lentiviral HCN4 gene transfer

Journal of Gene Medicine

Volumn 10, Issue 5, 2008, Pages 487-497

  Boink, Gerard J J ^a,b   Verkerk, Arie O ^a   van Amersfoorth, Shirley C M ^a   Tasseron, Sara J ^a   van der Rijt, Roos ^a   Bakker, Diane ^a   Linnenbank, André C ^a   van der Meulen, Jan ^a   de Bakker, Jacques M T ^a,b   Seppen, Jurgen ^a   Tan, Hanno L ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b ROYAL NETHERLANDS ACADEMY OF ARTS AND SCIENCES   (Netherlands)

Author keywords

Autonomic modulation; Ion channels; Lentiviral vectors; Pacemakers

Indexed keywords

CATION CHANNEL; CYCLIC AMP; HYPERPOLARIZATION ACTIVATED CYCLIC NUCLEOTIDE GATED CHANNEL 4; LENTIVIRUS VECTOR;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ARTIFICIAL HEART PACEMAKER; AUTONOMIC INNERVATION; BIOENGINEERING; CARDIOVASCULAR GENE THERAPY; CARDIOVASCULAR RESPONSE; CONTROLLED STUDY; ELECTROCARDIOGRAM; GENE FUNCTION; GENE OVEREXPRESSION; GENETIC ENGINEERING; GENETIC TRANSDUCTION; HEART DEPOLARIZATION; HEART ELECTROPHYSIOLOGY; HEART MUSCLE CELL; HEART MUSCLE POTENTIAL; HEART RATE; HUMAN; HUMAN CELL; HUMAN TISSUE; LENTIVIRINAE; MONOLAYER CULTURE; NEWBORN; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; SINUS NODE MEMBRANE POTENTIAL; VIRAL GENE DELIVERY SYSTEM; VIRUS GENE;

ACTION POTENTIALS; ANIMALS; BIOLOGICAL CLOCKS; CELL LINE; CYCLIC NUCLEOTIDE-GATED CATION CHANNELS; ELECTROPHYSIOLOGY; GENETIC VECTORS; HUMANS; LENTIVIRUS; MUSCLE PROTEINS; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; RATS; TISSUE ENGINEERING; TRANSDUCTION, GENETIC;

RATTUS;

EID: 44449156318     PISSN: 1099498X     EISSN: 15212254     Source Type: Journal    
DOI: 10.1002/jgm.1172     Document Type: Article

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