Expression and anatomical distribution of TIM-containing molecules in Langerhans cell sarcoma

Journal of Molecular Histology

Volumn 44, Issue 2, 2013, Pages 213-220

  Li, Jingwei ^a   Cao, Dayan ^a   Guo, Guoning ^a   Wu, Yuzhang ^a   Chen, Yongwen ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

B7 superfamily; Immunohistochemistry; Langerhans cell sarcoma; Langerin; T cell immunoglobulin and mucin domain containing molecules

Indexed keywords

B7 H3 ANTIGEN; CD16 ANTIGEN; CD31 ANTIGEN; CD68 ANTIGEN; CYTOKERATIN 18; GLYCOPROTEIN P 15095; KIDNEY INJURY MOLECULE 1; LYMPHOCYTE ANTIGEN; PROGRAMMED DEATH 1 LIGAND 1; T CELL IMMUNOGLOBULIN AND MUCIN DOMAIN 2; T CELL IMMUNOGLOBULIN AND MUCIN DOMAIN 3; T CELL IMMUNOGLOBULIN AND MUCIN DOMAIN 4; UNCLASSIFIED DRUG; V SET DOMAIN CONTAINING T CELL ACTIVATION INHIBITOR 1; VIRUS RECEPTOR;

ARTICLE; CD3+ T LYMPHOCYTE; CELL TYPE; CONTROLLED STUDY; DENDRITIC CELL; DISEASE ASSOCIATION; EPITHELIUM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; LANGERHANS CELL SARCOMA; MACROPHAGE; NATURAL KILLER CELL; OUTCOME ASSESSMENT; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SARCOMA CELL;

EID: 84878596379     PISSN: 15672379     EISSN: 15672387     Source Type: Journal    
DOI: 10.1007/s10735-012-9475-2     Document Type: Article

References (26)

1. Anderson AC (2012) Tim-3, a negative regulator of anti-tumor immunity. Curr Opin Immunol 24(2):213-216
2. Chiba S, Baghdadi M, Akiba H et al (2012) Tumor-infiltrating DCs suppress nucleic acid-mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1. Nat Immunol 13(9):832-842
3. Freeman GJ, Casasnovas JM, Umetsu DT et al (2010) TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity. Immunol Rev 235(1):172-189
4. Hashiguchi M, Kobori H, Ritprajak P et al (2008) Triggering receptor expressed on myeloid cell-like transcript 2 (TLT-2) is a counter-receptor for B7-H3 and enhances T cell responses. Proc Natl Acad Sci USA 105(2008):10495- 10500
5. He W, Fang Z, Wang F et al (2010) Galectin-9 significantly prolongs the survival of fully mismatched cardiac allografts in mice. Transplantation 88(6):782-790
6. Huang X, Bai X, Cao Y et al (2010) Lymphoma endothelium preferentially expresses Tim-3 and facilitates the progression of lymphoma by mediating immune evasion. J Exp Med 207(3):505-520
7. Lau SK, Chu PG, Weiss LM (2008) Immunohistochemical expression of Langerin in Langerhans cell histiocytosis and non-Langerhans cell histiocytic disorders. Am J Surg Pathol 32(4):615-619
8. Li H, Wang C, Guo G et al (2012a) The characteristic expression of B7-associated proteins in Langerhans cell sarcoma. Acta Histochem 114(7):733-743
9. Li H, Wu K, Tao K et al (2012b) Tim-3/galectin-9 signaling pathway mediates T cell dysfunction and predicts poor prognosis in patients with HBV-associated hepatocellular carcinoma. Hepatology
10. Miyanishi M, Tada K, Koike M et al (2007) Identification of Tim4 as a phosphatidylserine receptor. Nature 450(7168):435-439
11. Monney L, Sabatos CA, Gaglia JL et al (2002) Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease. Nature 415(6871):536-541
12. Nakayama M, Akiba H, Takeda K et al (2009) Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation. Blood 113(16):3821-3830
13. Nakayama M, Takahashi K, Hori M et al (2010) Langerhans cell sarcoma of the cervical lymph node: a case report and literature review. Auris Nasus Larynx 37(6):750-753
14. Nozaki Y, Nikolic-Paterson DJ, Snelgrove SL et al (2012) Endogenous Tim-1 (Kim-1) promotes T-cell responses and cell-mediated injury in experimental crescentic glomerulonephritis. Kidney Int 81(9):844-855
15. Rennert PD (2011) Novel roles for TIM-1 in immunity and infection. Immunol Lett 141(1):28-35
16. Rodriguez-Manzanet R, DeKruyff R, Kuchroo VK et al (2009) The costimulatory role of TIM molecules. Immunol Rev 229(1):259-270
17. Rodriguez-Manzanet R, Sanjuan MA, Wu HY et al (2010) T and B cell hyperactivity and autoimmunity associated with niche-specific defects in apoptotic body clearance in TIM-4-deficient mice. Proc Natl Acad Sci USA 107(19):8706-8711
18. Sánchez-Fueyo A, Tian J, Picarella D et al (2003) Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance. Nat Immunol 4(11):1093-1101
19. Saresella M, Rainone V, Al-Daghri NM et al (2012) The PD-1/PD-L1 pathway in human pathology. Curr Mol Med 12(3):259-267
20. Seki M, Oomizu S, Sakata KM et al (2008) Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis. Clin Immunol 127(1):78-88
21. Sica GL, Choi IH, Zhu G et al (2003) B7-H4, a molecule of the B7 family, negatively regulates T cell immunity. Immunity 18(6):849-861
22. Sonar SS, Hsu YM, Conrad ML et al (2010) Antagonism of TIM-1 blocks the development of disease in a humanized mouse model of allergic asthma. J Clin Invest 120(8):2767-2781
23. Uchida K, Kobayashi S, Inukai T et al (2008) Langerhans cell sarcoma emanating from the upper arm skin: successful treatment by MAID regimen. J Orthop Sci 13:89-93
24. Wong K, Valdez PA, Tan C et al (2010) Phosphatidylserine receptor Tim-4 is essential for the maintenance of the homeostatic state of resident peritoneal macrophages. Proc Natl Acad Sci USA 107(19):8712-8717
25. Yang PC, Xing Z, Berin CM et al (2007) TIM-4 expressed by mucosal dendritic cells plays a critical role in food antigen-specific Th2 differentiation and intestinal allergy. Gastroenterology 133(5):1522-1533
26. Zhuang X, Zhang X, Xia X et al (2012) Ectopic expression of TIM-3 in lung cancers: a potential independent prognostic factor for patients with NSCLC. Am J Clin Pathol 137(6):978-985